Framework for identifying chemicals with structural features associated with the potential to act as developmental or reproductive toxicants

Chemical Research in Toxicology

Volumn 26, Issue 12, 2013, Pages 1840-1861

  Wu, Shengde ^a   Fisher, Joan ^a   Naciff, Jorge ^a   Laufersweiler, Michael ^a   Lester, Cathy ^a   Daston, George ^a   Blackburn, Karen ^a  

^a PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHOXYETHANOL; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3,7 DIMETHYL 9 (2,6,6 TRIMETHYLCYCLOHEX 1 ENYL)NONA 2,4,6,8 TETRAENOIC ACID; DIETHYLSTILBESTROL; FUNCTIONAL GROUP; GESTAGEN; HYDROCORTISONE; LAURIC ACID; ORGANIC COMPOUND; ORGANOPHOSPHATE; RETINOID DERIVATIVE; UNCLASSIFIED DRUG; VALPROIC ACID; AROMATIC HYDROCARBON RECEPTOR; PROSTAGLANDIN RECEPTOR; RETINOIC ACID RECEPTOR; STEROID RECEPTOR;

ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; CHEMICAL STRUCTURE; CHOLESTEROL SYNTHESIS; COMPUTER MODEL; DECISION TREE; DEVELOPMENTAL TOXICITY; EXPERT SYSTEM; HUMAN; IN VITRO STUDY; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RECEPTOR BINDING; REPRODUCTIVE TOXICITY; RISK ASSESSMENT; ANIMAL; CHEMISTRY; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; REPRODUCTION; TOXICITY; TOXICITY TESTING;

ANIMALS; DECISION TREES; GROWTH AND DEVELOPMENT; HUMANS; MOLECULAR STRUCTURE; ORGANIC CHEMICALS; RECEPTORS, ARYL HYDROCARBON; RECEPTORS, PROSTAGLANDIN; RECEPTORS, RETINOIC ACID; RECEPTORS, STEROID; REPRODUCTION; TOXICITY TESTS;

EID: 84890474514     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx400226u     Document Type: Article

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