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Volumn 71, Issue 5 SUPPL., 2000, Pages

Role of cholesterol in embryonic development

Author keywords

7 dehydrocholesterol; AY 9944; BM 15766; Cholesterol; Holoprosencephaly; Limb anomalies; Masculinization deficiency; Rats; Smith Lemli Opitz syndrome; Sonic hedgehog; Triparanol

Indexed keywords

7 DEHYDROCHOLESTEROL; CLOMIFENE; TRIPARANOL;

EID: 0034016536     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/71.5.1270s     Document Type: Conference Paper
Times cited : (119)

References (41)
  • 1
    • 0001534522 scopus 로고
    • Action tératogène du triparanol chez l'animal
    • in French
    • Roux C. Action tératogène du triparanol chez l'animal. (Teratogenic action of triparanol in animal.) Arch Fr Pediatr 1964;21:451-64 (in French).
    • (1964) Arch Fr Pediatr , vol.21 , pp. 451-464
    • Roux, C.1
  • 2
    • 17444439499 scopus 로고
    • Action tératogène chez le rat d'un inhibiteur de la synthèse du cholestérol, le AY9944
    • in French
    • Roux C, Aubry A. Action tératogène chez le rat d'un inhibiteur de la synthèse du cholestérol, le AY9944. (Teratogenic action of AY9944, an inhibitor of cholesterol synthesis, in rat.) C R Soc Biol 1966;160:1353-7 (in French).
    • (1966) C R Soc Biol , vol.160 , pp. 1353-1357
    • Roux, C.1    Aubry, A.2
  • 3
    • 0010274888 scopus 로고
    • Action tératogène d'un inhibiteur de la synthèse du cholestérol, le AY9944, sur différentes espèces animales
    • in French
    • Roux C, Aubry M, Dupuis R. Action tératogène d'un inhibiteur de la synthèse du cholestérol, le AY9944, sur différentes espèces animales. (Teratogenic action of AY9944, an inhibitor of cholesterol synthesis, in several animal species.) C R Soc Biol 1969;163:327-32 (in French).
    • (1969) C R Soc Biol , vol.163 , pp. 327-332
    • Roux, C.1    Aubry, M.2    Dupuis, R.3
  • 4
    • 0030664545 scopus 로고    scopus 로고
    • Cholesterol biosynthesis inhibited by BM15766 induces holoprosencephaly in the rat
    • Kolf M, Chevy F, Silliart B, et al. Cholesterol biosynthesis inhibited by BM15766 induces holoprosencephaly in the rat. Teratology 1997;56:188-200.
    • (1997) Teratology , vol.56 , pp. 188-200
    • Kolf, M.1    Chevy, F.2    Silliart, B.3
  • 5
    • 0000139419 scopus 로고
    • A newly recognized syndrome of multiple congenital anomalies
    • Smith DW, Lemli L, Opitz JM. A newly recognized syndrome of multiple congenital anomalies. J Pediatr 1964;64:210-7.
    • (1964) J Pediatr , vol.64 , pp. 210-217
    • Smith, D.W.1    Lemli, L.2    Opitz, J.M.3
  • 6
    • 85046045003 scopus 로고
    • Cholesterol defect in Smith-Lemli-Opitz syndrome
    • letter
    • Tint GS. Cholesterol defect in Smith-Lemli-Opitz syndrome. Am J Obstet Gynecol 1993;47:473-4 (letter).
    • (1993) Am J Obstet Gynecol , vol.47 , pp. 473-474
    • Tint, G.S.1
  • 7
    • 0029844192 scopus 로고    scopus 로고
    • Cholesterol modification of hedgehog signaling proteins in animal development
    • Porter JA, Young KE, Beachy PA. Cholesterol modification of hedgehog signaling proteins in animal development. Science 1996;274:255-9.
    • (1996) Science , vol.274 , pp. 255-259
    • Porter, J.A.1    Young, K.E.2    Beachy, P.A.3
  • 8
    • 0031044526 scopus 로고    scopus 로고
    • Pathogenesis of malformations in a rodent model for Smith-Lemli-Opitz syndrome
    • Dehart DB, Lanoue L, Tint GS, Sulik KK. Pathogenesis of malformations in a rodent model for Smith-Lemli-Opitz syndrome. Am J Med Genet 1997;68:328-37.
    • (1997) Am J Med Genet , vol.68 , pp. 328-337
    • Dehart, D.B.1    Lanoue, L.2    Tint, G.S.3    Sulik, K.K.4
  • 9
    • 0029939653 scopus 로고    scopus 로고
    • 7-reductase by novel 6-aza-B-homosteroids and other analogs of a presumptive carbocationic intermediate of the reduction reaction
    • 7-reductase by novel 6-aza-B-homosteroids and other analogs of a presumptive carbocationic intermediate of the reduction reaction. Biochemistry 1996;35:7069-76.
    • (1996) Biochemistry , vol.35 , pp. 7069-7076
    • Rahier, A.1    Taton, M.2
  • 10
    • 0019134397 scopus 로고
    • Teratogenic effect of an inhibitor of cholesterol synthesis (AY9944) in rats: Correlation with maternal cholesterolemia
    • Roux C, Dupuis R, Horvath C, Talbot JN. Teratogenic effect of an inhibitor of cholesterol synthesis (AY9944) in rats: correlation with maternal cholesterolemia. J Nutr 1980;110:2310-2.
    • (1980) J Nutr , vol.110 , pp. 2310-2312
    • Roux, C.1    Dupuis, R.2    Horvath, C.3    Talbot, J.N.4
  • 11
    • 0021189528 scopus 로고
    • Teratogenic effect of AY9944 in rats: Importance of day of administration and maternal cholesterolemia
    • Barbu V, Roux C, Dupuis R, Gardette J, Maziere JC. Teratogenic effect of AY9944 in rats: importance of day of administration and maternal cholesterolemia. Proc Soc Exp Biol Med 1984;176:54-9.
    • (1984) Proc Soc Exp Biol Med , vol.176 , pp. 54-59
    • Barbu, V.1    Roux, C.2    Dupuis, R.3    Gardette, J.4    Maziere, J.C.5
  • 12
    • 0018411725 scopus 로고
    • Teratogenic action and embryolethality of AY9944: Prevention by a hypercholesterolemia-provoking diet
    • Roux C, Horvath C, Dupuis R. Teratogenic action and embryolethality of AY9944: prevention by a hypercholesterolemia-provoking diet. Teratology 1979;19:35-8.
    • (1979) Teratology , vol.19 , pp. 35-38
    • Roux, C.1    Horvath, C.2    Dupuis, R.3
  • 13
    • 0343904157 scopus 로고    scopus 로고
    • Respective role of cholesterol shortage and precursor accumulation in the teratogenic effects of distal inhibition of cholesterol synthesis
    • 25th Conference of the European Teratology Society Cannes, 14-17 September 1997 abstr P51
    • Gaoua W, Haddadi K, Wolf C, et al. Respective role of cholesterol shortage and precursor accumulation in the teratogenic effects of distal inhibition of cholesterol synthesis. 25th Conference of the European Teratology Society. Cannes, 14-17 September 1997. Teratology 1997;56:398 (abstr P51).
    • (1997) Teratology , vol.56 , pp. 398
    • Gaoua, W.1    Haddadi, K.2    Wolf, C.3
  • 14
    • 0343032617 scopus 로고    scopus 로고
    • An animal model of Smith-Lemli-Opitz syndrome disorders of masculinization
    • 25th Conference of the European Teratology Society, Cannes, 14-17 September 1997. abstr P49
    • Haddadi K, Gaoua W, Wolf C, et al. An animal model of Smith-Lemli-Opitz syndrome disorders of masculinization. 25th Conference of the European Teratology Society, Cannes, 14-17 September 1997. Teratology 1997;56:398 (abstr P49).
    • (1997) Teratology , vol.56 , pp. 398
    • Haddadi, K.1    Gaoua, W.2    Wolf, C.3
  • 15
    • 0025605393 scopus 로고
    • Teratogenic effect of the cholesterol synthesis inhibitor AY9944 on rat embryos in vitro
    • Repetto M, Citadelle D, Dupuis R, et al. Teratogenic effect of the cholesterol synthesis inhibitor AY9944 on rat embryos in vitro. Teratology 1990;42:611-8.
    • (1990) Teratology , vol.42 , pp. 611-618
    • Repetto, M.1    Citadelle, D.2    Dupuis, R.3
  • 18
    • 0020040173 scopus 로고
    • Preimplantation mouse embryos synthesize membrane sterols
    • Pratt HPM. Preimplantation mouse embryos synthesize membrane sterols. Dev Biol 1982;89:101-10.
    • (1982) Dev Biol , vol.89 , pp. 101-110
    • Pratt, H.P.M.1
  • 19
    • 0343904156 scopus 로고    scopus 로고
    • Toxicity of cholesterol precursor and oxidized by-products accumulated in Smith-Lemli-Opitz syndrome
    • 25th Conference of the European Teratology Society, Cannes, 14-17 September 1997. abstr P50
    • Gaoua W, Wolf C, Chevy F, et al. Toxicity of cholesterol precursor and oxidized by-products accumulated in Smith-Lemli-Opitz syndrome. 25th Conference of the European Teratology Society, Cannes, 14-17 September 1997. Teratology 1997;56:398 (abstr P50).
    • (1997) Teratology , vol.56 , pp. 398
    • Gaoua, W.1    Wolf, C.2    Chevy, F.3
  • 20
    • 0021636508 scopus 로고
    • Effects of AY9944 on low density lipoprotein metabolism in cultured human fibroblasts
    • Maziere JC, Maziere C, Mora I. et al. Effects of AY9944 on low density lipoprotein metabolism in cultured human fibroblasts. Chem Biophys Res Commun 1984;122:955-9.
    • (1984) Chem Biophys Res Commun , vol.122 , pp. 955-959
    • Maziere, J.C.1    Maziere, C.2    Mora, I.3
  • 21
    • 0030458446 scopus 로고    scopus 로고
    • Holoprosencephaly in RSH/Smith-Lemli-Opitz syndrome: Does abnormal cholesterol metabolism affect the function of sonic hedgehog?
    • Kelley RI, Roessler E, Hennekam RCM, et al. Holoprosencephaly in RSH/Smith-Lemli-Opitz syndrome: does abnormal cholesterol metabolism affect the function of sonic hedgehog? Am J Med Genet 1996;66:478-84.
    • (1996) Am J Med Genet , vol.66 , pp. 478-484
    • Kelley, R.I.1    Roessler, E.2    Hennekam, R.C.M.3
  • 22
    • 0023851444 scopus 로고
    • Lethal acrodysgenital dwarfism: A severe lethal condition resembling Smith-Lemli-Opitz syndrome
    • Le Merrer M, Briard ML, Girard S, Mulliez N, Moraine C, Imbert MC. Lethal acrodysgenital dwarfism: a severe lethal condition resembling Smith-Lemli-Opitz syndrome. J Med Genet 1988;25:88-95.
    • (1988) J Med Genet , vol.25 , pp. 88-95
    • Le Merrer, M.1    Briard, M.L.2    Girard, S.3    Mulliez, N.4    Moraine, C.5    Imbert, M.C.6
  • 23
    • 0030716476 scopus 로고    scopus 로고
    • Limb, genital, CNS and facial malformations result from gene/environment-induced cholesterol deficiency: Further evidence for a link to sonic hedgehog
    • Lanouc L, Dehart DB, Hinsdale ME, Maeda N, Tint GS, Sulik KK. Limb, genital, CNS and facial malformations result from gene/environment-induced cholesterol deficiency: further evidence for a link to sonic hedgehog. Am J Med Genet 1997;73:24-31.
    • (1997) Am J Med Genet , vol.73 , pp. 24-31
    • Lanouc, L.1    Dehart, D.B.2    Hinsdale, M.E.3    Maeda, N.4    Tint, G.S.5    Sulik, K.K.6
  • 24
    • 0029933263 scopus 로고    scopus 로고
    • A novel function for apolipoprotein B: Lipoprotein synthesis in the yolk sac is critical for maternal-fetal lipid transport in mice
    • Farese RV, Cases S, Ruland SL, et al. A novel function for apolipoprotein B: lipoprotein synthesis in the yolk sac is critical for maternal-fetal lipid transport in mice. J Lipid Res 1996;37:347-60.
    • (1996) J Lipid Res , vol.37 , pp. 347-360
    • Farese, R.V.1    Cases, S.2    Ruland, S.L.3
  • 25
    • 0000727177 scopus 로고
    • Defective cholesterol biosynthesis associated with the Smith-Lemli-Opitz syndrome
    • Tint GS, Irons M, Elias ER, et al. Defective cholesterol biosynthesis associated with the Smith-Lemli-Opitz syndrome. N Engl J Med 1994;330:107-13.
    • (1994) N Engl J Med , vol.330 , pp. 107-113
    • Tint, G.S.1    Irons, M.2    Elias, E.R.3
  • 26
    • 8944258115 scopus 로고    scopus 로고
    • Abnormal cholesterol biosynthesis in the Smith-Lemli-Opitz and the lethal acrodysgenital syndromes
    • Cormier-Daire V, Wolf C, Le Merrer M, et al. Abnormal cholesterol biosynthesis in the Smith-Lemli-Opitz and the lethal acrodysgenital syndromes. Eur J Pediatr 1996;155:656-9.
    • (1996) Eur J Pediatr , vol.155 , pp. 656-659
    • Cormier-Daire, V.1    Wolf, C.2    Le Merrer, M.3
  • 27
    • 0031050244 scopus 로고    scopus 로고
    • Clinical effect of cholesterol supplementation in six patients with the Smith-Lemli-Opitz syndrome (SLOS)
    • Eliaser, Irons M, Hurley AD, Tint GS, Salen G. Clinical effect of cholesterol supplementation in six patients with the Smith-Lemli-Opitz syndrome (SLOS). Am J Med Genet 1997;68:305-10.
    • (1997) Am J Med Genet , vol.68 , pp. 305-310
    • Eliaser1    Irons, M.2    Hurley, A.D.3    Tint, G.S.4    Salen, G.5
  • 28
    • 0031051150 scopus 로고    scopus 로고
    • Treatment of Smith-Lemli-Opitz syndrome: Results of a multicenter trial
    • Irons M, Elias ER, Abuelo D, et al. Treatment of Smith-Lemli-Opitz syndrome: results of a multicenter trial. Am J Med Genet 1997; 68:311-4.
    • (1997) Am J Med Genet , vol.68 , pp. 311-314
    • Irons, M.1    Elias, E.R.2    Abuelo, D.3
  • 30
    • 0029079893 scopus 로고
    • Distribution of sonic hedgehog peptides in the developing chick and mouse embryo
    • Marti E, Takada R, Bumcrot DA, Sasaki H, Mc Mahon AP. Distribution of sonic hedgehog peptides in the developing chick and mouse embryo. Development 1995;121:2537-47.
    • (1995) Development , vol.121 , pp. 2537-2547
    • Marti, E.1    Takada, R.2    Bumcrot, D.A.3    Sasaki, H.4    Mc Mahon, A.P.5
  • 31
    • 0029777408 scopus 로고    scopus 로고
    • Cyclopia and defective axial patterning in mice lacking sonic hedgehog gene function
    • Chiang C, Litingtung Y, Lee E, et al. Cyclopia and defective axial patterning in mice lacking sonic hedgehog gene function. Nature 1996;383:407-13.
    • (1996) Nature , vol.383 , pp. 407-413
    • Chiang, C.1    Litingtung, Y.2    Lee, E.3
  • 32
    • 0030294408 scopus 로고    scopus 로고
    • Mutations in the human sonic hedgehog gene cause holoprosencephaly
    • Roessler H, Belloni E, Gaudenz K, et al. Mutations in the human sonic hedgehog gene cause holoprosencephaly. Nat Genet 1996;14:357-60.
    • (1996) Nat Genet , vol.14 , pp. 357-360
    • Roessler, H.1    Belloni, E.2    Gaudenz, K.3
  • 33
    • 0343468339 scopus 로고    scopus 로고
    • Expression domains of five developmental genes in early fore- And midbrain after inhibition of cholesterol biosynthesis in rat embryos
    • 25th Conference of the European Teratology Society,. Cannes, 14-17 September 1997. abstr P29
    • Kolf M, Clotman F, Roux C, Picard J. Expression domains of five developmental genes in early fore-and midbrain after inhibition of cholesterol biosynthesis in rat embryos. 25th Conference of the European Teratology Society,. Cannes, 14-17 September 1997. Teratology 1997;56:393 (abstr P29).
    • (1997) Teratology , vol.56 , pp. 393
    • Kolf, M.1    Clotman, F.2    Roux, C.3    Picard, J.4
  • 34
    • 0011102935 scopus 로고    scopus 로고
    • The tumor suppressor gene patched encodes candidate receptor for sonic hedgehog
    • Stone DM, Hynes M, Ardmanini M, et al. The tumor suppressor gene patched encodes candidate receptor for sonic hedgehog. Nature 1996;384:129-34.
    • (1996) Nature , vol.384 , pp. 129-134
    • Stone, D.M.1    Hynes, M.2    Ardmanini, M.3
  • 35
    • 0030869843 scopus 로고    scopus 로고
    • Recent advances in hedgehog signalling
    • Tabin CJ, Mc Mahon AP. Recent advances in hedgehog signalling. Trends Cell Biol 1997;7:442-6.
    • (1997) Trends Cell Biol , vol.7 , pp. 442-446
    • Tabin, C.J.1    Mc Mahon, A.P.2
  • 36
    • 0032421354 scopus 로고    scopus 로고
    • Functions of lipid rafts in biological membranes
    • Brown DA, London E. Functions of lipid rafts in biological membranes. Annu Rev Cell Dev Biol 1998;14:111-36.
    • (1998) Annu Rev Cell Dev Biol , vol.14 , pp. 111-136
    • Brown, D.A.1    London, E.2
  • 37
    • 0022859473 scopus 로고
    • LM cell growth and membrane lipid adaptation to sterol structure
    • Rujanavech C, Silberet DF. LM cell growth and membrane lipid adaptation to sterol structure. J Biol Chem 1986;261:7196-203.
    • (1986) J Biol Chem , vol.261 , pp. 7196-7203
    • Rujanavech, C.1    Silberet, D.F.2
  • 38
    • 0031919848 scopus 로고    scopus 로고
    • 7-Dehydrocholesterol down-regulates cholesterol biosynthesis in cultured Smith-Lemli-Opitz syndrome skin fibroblasts
    • Honda M, Tint GS, Honda A, Nguyen LB, Chen TS, Shefer S. 7-Dehydrocholesterol down-regulates cholesterol biosynthesis in cultured Smith-Lemli-Opitz syndrome skin fibroblasts. J Lipid Res 1998;39:647-57.
    • (1998) J Lipid Res , vol.39 , pp. 647-657
    • Honda, M.1    Tint, G.S.2    Honda, A.3    Nguyen, L.B.4    Chen, T.S.5    Shefer, S.6
  • 40
    • 0029775625 scopus 로고    scopus 로고
    • Defective forebrain development in mice lacking gp330/megalin
    • Willnow TE, Hilpert J, Armstrong SA, et al. Defective forebrain development in mice lacking gp330/megalin. Proc Natl Acad Sci U S A 1996;93:8460-4.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 8460-8464
    • Willnow, T.E.1    Hilpert, J.2    Armstrong, S.A.3
  • 41
    • 0032486433 scopus 로고    scopus 로고
    • Teratogen-mediated inhibition of target tissue response to Shh signaling
    • Cooper MK, Porter JA, Young KE, Beachy PA. Teratogen-mediated inhibition of target tissue response to Shh signaling. Science 1998;280:1603-7.
    • (1998) Science , vol.280 , pp. 1603-1607
    • Cooper, M.K.1    Porter, J.A.2    Young, K.E.3    Beachy, P.A.4


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