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Volumn 41, Issue 22, 2013, Pages 10334-10344

ATR kinase activation in G1 phase facilitates the repair of ionizing radiation-induced DNA damage

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN; CHECKPOINT KINASE 1; REPLICATION FACTOR A;

EID: 84890420876     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt833     Document Type: Article
Times cited : (58)

References (41)
  • 1
    • 78649336706 scopus 로고    scopus 로고
    • The DNA damage response: Making it safe to play with knives
    • Ciccia, A. and Elledge, S.J. (2010) The DNA damage response: making it safe to play with knives. Mol. Cell, 40, 179-204.
    • (2010) Mol. Cell , vol.40 , pp. 179-204
    • Ciccia, A.1    Elledge, S.J.2
  • 2
    • 84855908936 scopus 로고    scopus 로고
    • Safeguarding genome integrity: The checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication
    • Sorensen, C.S. and Syljuasen, R.G. (2012) Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication. Nucleic Acids Res., 40, 477-486.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 477-486
    • Sorensen, C.S.1    Syljuasen, R.G.2
  • 3
    • 0032472330 scopus 로고    scopus 로고
    • Overexpression of a kinase-inactive ATR protein causes sensitivity to DNAdamaging agents and defects in cell cycle checkpoints
    • Cliby, W.A., Roberts, C.J., Cimprich, K.A., Stringer, C.M., Lamb, J.R., Schreiber, S.L. and Friend, S.H. (1998) Overexpression of a kinase-inactive ATR protein causes sensitivity to DNAdamaging agents and defects in cell cycle checkpoints. EMBO J., 17, 159-169.
    • (1998) EMBO J , vol.17 , pp. 159-169
    • Cliby, W.A.1    Roberts, C.J.2    Cimprich, K.A.3    Stringer, C.M.4    Lamb, J.R.5    Schreiber, S.L.6    Friend, S.H.7
  • 4
    • 0032560556 scopus 로고    scopus 로고
    • Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control
    • Wright, J.A., Keegan, K.S., Herendeen, D.R., Bentley, N.J., Carr, A.M., Hoekstra, M.F. and Concannon, P. (1998) Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control. Proc. Natl Acad. Sci. USA, 95, 7445-7450.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 7445-7450
    • Wright, J.A.1    Keegan, K.S.2    Herendeen, D.R.3    Bentley, N.J.4    Carr, A.M.5    Hoekstra, M.F.6    Concannon, P.7
  • 6
    • 66149114020 scopus 로고    scopus 로고
    • Human CtIP mediates cell cycle control of DNA end resection and double strand break repair
    • Huertas, P. and Jackson, S.P. (2009) Human CtIP mediates cell cycle control of DNA end resection and double strand break repair. J. Biol. Chem., 284, 9558-9565.
    • (2009) J. Biol. Chem , vol.284 , pp. 9558-9565
    • Huertas, P.1    Jackson, S.P.2
  • 7
    • 77954313601 scopus 로고    scopus 로고
    • DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints
    • You, Z. and Bailis, J.M. (2010) DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints. Trends Cell Biol., 20, 402-409.
    • (2010) Trends Cell Biol. , vol.20 , pp. 402-409
    • You, Z.1    Bailis, J.M.2
  • 9
    • 0008158443 scopus 로고
    • Radiosensitivity in ataxiatelangiectasia: A new explanation
    • Painter, R.B. and Young, B.R. (1980) Radiosensitivity in ataxiatelangiectasia: a new explanation. Proc. Natl Acad. Sci. USA, 77, 7315-7317.
    • (1980) Proc. Natl Acad. Sci. USA , vol.77 , pp. 7315-7317
    • Painter, R.B.1    Young, B.R.2
  • 10
    • 0034102337 scopus 로고    scopus 로고
    • ATR disruption leads to chromosomal fragmentation and early embryonic lethality
    • Brown, E.J. and Baltimore, D. (2000) ATR disruption leads to chromosomal fragmentation and early embryonic lethality. Genes Dev., 14, 397-402.
    • (2000) Genes Dev , vol.14 , pp. 397-402
    • Brown, E.J.1    Baltimore, D.2
  • 14
    • 84864658339 scopus 로고    scopus 로고
    • Identification and characterization of human apurinic/apyrimidinic endonuclease-1 inhibitors
    • Srinivasan, A., Wang, L., Cline, C.J., Xie, Z., Sobol, R.W., Xie, X.Q. and Gold, B. (2012) Identification and characterization of human apurinic/apyrimidinic endonuclease-1 inhibitors. Biochemistry, 51, 6246-6259.
    • (2012) Biochemistry , vol.51 , pp. 6246-6259
    • Srinivasan, A.1    Wang, L.2    Cline, C.J.3    Xie, Z.4    Sobol, R.W.5    Xie, X.Q.6    Gold, B.7
  • 19
    • 77958498222 scopus 로고    scopus 로고
    • The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer
    • Smith, J., Tho, L.M., Xu, N. and Gillespie, D.A. (2010) The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer. Adv. Cancer Res., 108, 73-112.
    • (2010) Adv. Cancer Res. , vol.108 , pp. 73-112
    • Smith, J.1    Tho, L.M.2    Xu, N.3    Gillespie, D.A.4
  • 21
    • 0034053130 scopus 로고    scopus 로고
    • The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01
    • Graves, P.R., Yu, L., Schwarz, J.K., Gales, J., Sausville, E.A., O'Connor, P.M. and Piwnica-Worms, H. (2000) The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01. J. Biol. Chem., 275, 5600-5605.
    • (2000) J. Biol. Chem , vol.275 , pp. 5600-5605
    • Graves, P.R.1    Yu, L.2    Schwarz, J.K.3    Gales, J.4    Sausville, E.A.5    O'Connor, P.M.6    Piwnica-Worms, H.7
  • 23
    • 0037665234 scopus 로고    scopus 로고
    • ATR kinase activity regulates the intranuclear translocation of ATR and RPA following ionizing radiation
    • Barr, S.M., Leung, C.G., Chang, E.E. and Cimprich, K.A. (2003) ATR kinase activity regulates the intranuclear translocation of ATR and RPA following ionizing radiation. Curr. Biol., 13, 1047-1051.
    • (2003) Curr. Biol , vol.13 , pp. 1047-1051
    • Barr, S.M.1    Leung, C.G.2    Chang, E.E.3    Cimprich, K.A.4
  • 24
    • 0027958344 scopus 로고
    • Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumour cell lines
    • Lukas, J., Pagano, M., Staskova, Z., Draetta, G. and Bartek, J. (1994) Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumour cell lines. Oncogene, 9, 707-718.
    • (1994) Oncogene , vol.9 , pp. 707-718
    • Lukas, J.1    Pagano, M.2    Staskova, Z.3    Draetta, G.4    Bartek, J.5
  • 27
    • 0035941021 scopus 로고    scopus 로고
    • ATR and ATRIP: Partners in checkpoint signaling
    • Cortez, D., Guntuku, S., Qin, J. and Elledge, S.J. (2001) ATR and ATRIP: partners in checkpoint signaling. Science, 294, 1713-1716.
    • (2001) Science , vol.294 , pp. 1713-1716
    • Cortez, D.1    Guntuku, S.2    Qin, J.3    Elledge, S.J.4
  • 28
    • 0037567268 scopus 로고    scopus 로고
    • Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
    • Zou, L. and Elledge, S.J. (2003) Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science, 300, 1542-1548.
    • (2003) Science , vol.300 , pp. 1542-1548
    • Zou, L.1    Elledge, S.J.2
  • 29
    • 84857785627 scopus 로고    scopus 로고
    • Cdk-mediated phosphorylation of Chk1 is required for efficient activation and full checkpoint proficiency in response to DNA damage
    • Xu, N., Libertini, S., Black, E.J., Lao, Y., Hegarat, N., Walker, M. and Gillespie, D.A. (2012) Cdk-mediated phosphorylation of Chk1 is required for efficient activation and full checkpoint proficiency in response to DNA damage. Oncogene, 31, 1086-1094.
    • (2012) Oncogene , vol.31 , pp. 1086-1094
    • Xu, N.1    Libertini, S.2    Black, E.J.3    Lao, Y.4    Hegarat, N.5    Walker, M.6    Gillespie, D.A.7
  • 31
    • 33748780358 scopus 로고    scopus 로고
    • Replication protein A directs loading of the DNA damage checkpoint clamp to 5'-DNA junctions
    • Majka, J., Binz, S.K., Wold, M.S. and Burgers, P.M. (2006) Replication protein A directs loading of the DNA damage checkpoint clamp to 5'-DNA junctions. J. Biol. Chem., 281, 27855-27861.
    • (2006) J. Biol. Chem , vol.281 , pp. 27855-27861
    • Majka, J.1    Binz, S.K.2    Wold, M.S.3    Burgers, P.M.4
  • 32
    • 4243156107 scopus 로고    scopus 로고
    • Biochemical characterization of DNA damage checkpoint complexes: Clamp loader and clamp complexes with specificity for 50 recessed DNA
    • Ellison, V. and Stillman, B. (2003) Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 50 recessed DNA. PLoS Biol., 1, E33.
    • (2003) PLoS Biol , vol.1
    • Ellison, V.1    Stillman, B.2
  • 33
    • 33644757806 scopus 로고    scopus 로고
    • TopBP1 activates the ATR-ATRIP complex
    • Kumagai, A., Lee, J., Yoo, H.Y. and Dunphy, W.G. (2006) TopBP1 activates the ATR-ATRIP complex. Cell, 124, 943-955.
    • (2006) Cell , vol.124 , pp. 943-955
    • Kumagai, A.1    Lee, J.2    Yoo, H.Y.3    Dunphy, W.G.4
  • 34
    • 44849093460 scopus 로고    scopus 로고
    • TopBP1 activates ATR through ATRIP and a PIKK regulatory domain
    • Mordes, D.A., Glick, G.G., Zhao, R. and Cortez, D. (2008) TopBP1 activates ATR through ATRIP and a PIKK regulatory domain. Genes Dev., 22, 1478-1489.
    • (2008) Genes Dev , vol.22 , pp. 1478-1489
    • Mordes, D.A.1    Glick, G.G.2    Zhao, R.3    Cortez, D.4
  • 35
    • 77949467495 scopus 로고    scopus 로고
    • Rad17 plays a central role in establishment of the interaction between TopBP1 and the Rad9-Hus1-Rad1 complex at stalled replication forks
    • Lee, J. and Dunphy, W.G. (2010) Rad17 plays a central role in establishment of the interaction between TopBP1 and the Rad9-Hus1-Rad1 complex at stalled replication forks. Mol. Biol. Cell, 21, 926-935.
    • (2010) Mol. Biol. Cell , vol.21 , pp. 926-935
    • Lee, J.1    Dunphy, W.G.2
  • 36
    • 34250705797 scopus 로고    scopus 로고
    • The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1
    • Delacroix, S., Wagner, J.M., Kobayashi, M., Yamamoto, K. and Karnitz, L.M. (2007) The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1. Genes Dev., 21, 1472-1477.
    • (2007) Genes Dev , vol.21 , pp. 1472-1477
    • Delacroix, S.1    Wagner, J.M.2    Kobayashi, M.3    Yamamoto, K.4    Karnitz, L.M.5
  • 37
    • 78149284014 scopus 로고    scopus 로고
    • TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint
    • Cescutti, R., Negrini, S., Kohzaki, M. and Halazonetis, T.D. (2010) TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint. EMBO J., 29, 3723-3732.
    • (2010) EMBO J. , vol.29 , pp. 3723-3732
    • Cescutti, R.1    Negrini, S.2    Kohzaki, M.3    Halazonetis, T.D.4
  • 38
    • 44349157094 scopus 로고    scopus 로고
    • Irreversible chromosome damage accumulates rapidly in the absence of ATM kinase activity
    • White, J.S., Choi, S. and Bakkenist, C.J. (2008) Irreversible chromosome damage accumulates rapidly in the absence of ATM kinase activity. Cell Cycle, 7, 1277-1284.
    • (2008) Cell Cycle , vol.7 , pp. 1277-1284
    • White, J.S.1    Choi, S.2    Bakkenist, C.J.3
  • 39
    • 77953837463 scopus 로고    scopus 로고
    • Transient ATM kinase inhibition disrupts DNA damage-induced sister chromatid exchange
    • White, J.S., Choi, S. and Bakkenist, C.J. (2010) Transient ATM kinase inhibition disrupts DNA damage-induced sister chromatid exchange. Sci. Signal., 3, ra44.
    • (2010) Sci. Signal. , vol.3
    • White, J.S.1    Choi, S.2    Bakkenist, C.J.3
  • 41
    • 77958489008 scopus 로고    scopus 로고
    • Inhibition of ATM kinase activity does not phenocopy ATM protein disruption: Implications for the clinical utility of ATM kinase inhibitors
    • Choi, S., Gamper, A.M., White, J.S. and Bakkenist, C.J. (2010) Inhibition of ATM kinase activity does not phenocopy ATM protein disruption: implications for the clinical utility of ATM kinase inhibitors. Cell Cycle, 9, 4052-4057.
    • (2010) Cell Cycle , vol.9 , pp. 4052-4057
    • Choi, S.1    Gamper, A.M.2    White, J.S.3    Bakkenist, C.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.