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Volumn 10, Issue 1, 2014, Pages 51-65

Evaluation of the pharmacokinetics and drug interactions of the two recently developed statins, rosuvastatin and pitavastatin

Author keywords

Drug interaction; Pharmacokinetics; Pitavastatin; Rosuvastatin; Statins

Indexed keywords

ATORVASTATIN; BREAST CANCER RESISTANCE PROTEIN; CYCLOSPORIN; DARUNAVIR PLUS RITONAVIR; ERYTHROMYCIN; FLUCONAZOLE; FLUINDOSTATIN; GEMFIBROZIL; GLIBENCLAMIDE; GLICLAZIDE; GLIMEPIRIDE; GLIPIZIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ITRACONAZOLE; KETOCONAZOLE; LOPINAVIR PLUS RITONAVIR; MEVINOLIN; PIOGLITAZONE; PITAVASTATIN; PRAVASTATIN; RIFAMPICIN; RITONAVIR; ROSUVASTATIN; SAQUINAVIR; SIMVASTATIN; TOLBUTAMIDE; TROGLITAZONE; URSOLIC ACID; WARFARIN;

EID: 84890363516     PISSN: 17425255     EISSN: 17447607     Source Type: Journal    
DOI: 10.1517/17425255.2014.851667     Document Type: Review
Times cited : (38)

References (157)
  • 1
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: Prospective meta-Analysis of data from 90,056 participants in 14 randomised trials of statins
    • Baigent C, Keech A, Kearney PM, et al. Efficacy and safety of cholesterol-lowering treatment: Prospective meta-Analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet 2005;366:1267-78
    • (2005) Lancet , vol.366 , pp. 1267-1278
    • Baigent, C.1    Keech, A.2    Kearney, P.M.3
  • 2
    • 40949117959 scopus 로고    scopus 로고
    • The efficacy and safety of intensive statin therapy: A meta-Analysis of randomized trials
    • Josan K, Majumdar SR, McAlister FA. The efficacy and safety of intensive statin therapy: A meta-Analysis of randomized trials. CMAJ 2008;178:576-84
    • (2008) CMAJ , vol.178 , pp. 576-584
    • Josan, K.1    Majumdar, S.R.2    McAlister, F.A.3
  • 3
    • 78449281377 scopus 로고    scopus 로고
    • Efficacy and safety of more intensive lowering of LDL cholesterol: A meta-Analysis of data from 170,000 participants in 26 randomised trials
    • Baigent C, Blackwell L, Emberson J, et al. Efficacy and safety of more intensive lowering of LDL cholesterol: A meta-Analysis of data from 170,000 participants in 26 randomised trials. Lancet 2010;376:1670-81
    • (2010) Lancet , vol.376 , pp. 1670-1681
    • Baigent, C.1    Blackwell, L.2    Emberson, J.3
  • 4
    • 33748042671 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3- methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: Drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions
    • Shitara Y, Sugiyama Y. Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: Drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions. Pharmacol Ther 2006;112:71-105
    • (2006) Pharmacol Ther , vol.112 , pp. 71-105
    • Shitara, Y.1    Sugiyama, Y.2
  • 5
    • 13444251203 scopus 로고    scopus 로고
    • Chemical, pharmacokinetic and pharmacodynamic properties of statins: An update
    • Schachter M. Chemical, pharmacokinetic and pharmacodynamic properties of statins: An update. Fundam Clin Pharmacol 2005;19:117-25
    • (2005) Fundam Clin Pharmacol , vol.19 , pp. 117-125
    • Schachter, M.1
  • 7
    • 76349092662 scopus 로고    scopus 로고
    • Human skeletal muscle drug transporters determine local exposure and toxicity of statins
    • Knauer MJ, Urquhart BL, Meyer zu Schwabedissen HE, et al. Human skeletal muscle drug transporters determine local exposure and toxicity of statins. Circ Res 2010;106:297-306
    • (2010) Circ Res , vol.106 , pp. 297-306
    • Knauer, M.J.1    Urquhart, B.L.2    Meyer, Z.U.3    Schwabedissen, H.E.4
  • 8
    • 78650553915 scopus 로고    scopus 로고
    • Pitavastatin-pharmacological profile from early phase studies
    • Catapano AL. Pitavastatin-pharmacological profile from early phase studies. Atheroscler Suppl 2010;11:3-7
    • (2010) Atheroscler Suppl , vol.11 , pp. 3-7
    • Catapano, A.L.1
  • 9
    • 0141560665 scopus 로고    scopus 로고
    • Comparative pharmacology of rosuvastatin
    • McTaggart F. Comparative pharmacology of rosuvastatin. Atheroscler Suppl 2003;4:9-14
    • (2003) Atheroscler Suppl , vol.4 , pp. 9-14
    • McTaggart, F.1
  • 12
    • 0141988934 scopus 로고    scopus 로고
    • Pitavastatin: Efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor
    • Kajinami K, Takekoshi N, Saito Y. Pitavastatin: Efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor. Cardiovasc Drug Rev 2003;21:199-215
    • (2003) Cardiovasc Drug Rev , vol.21 , pp. 199-215
    • Kajinami, K.1    Takekoshi, N.2    Saito, Y.3
  • 13
    • 23044512011 scopus 로고    scopus 로고
    • Effect of rosuvastatin on warfarin pharmacodynamics and pharmacokinetics
    • Simonson SG, Martin PD, Mitchell PD, et al. Effect of rosuvastatin on warfarin pharmacodynamics and pharmacokinetics. J Clin Pharmacol 2005;45:927-34
    • (2005) J Clin Pharmacol , vol.45 , pp. 927-934
    • Simonson, S.G.1    Martin, P.D.2    Mitchell, P.D.3
  • 14
    • 84890318589 scopus 로고    scopus 로고
    • Kowa Pharmaceuticals America. IncPackage Insert (Version Of October 2012). Montgomery AL 36117, USA
    • Kowa Pharmaceuticals America, Inc. Livalo (pitavastatin) Package Insert (Version of October 2012). Montgomery, AL 36117, USA
    • Livalo (pitavastatin
  • 15
    • 2342456519 scopus 로고    scopus 로고
    • AstraZeneca Pharmaceuticals LPPackage Insert: Revised 0107. Wilmington DE USA
    • AstraZeneca Pharmaceuticals LP. Crestor (rosuvastatin calcium) Package Insert: Revised 01/07. Wilmington, DE, USA
    • Crestor (rosuvastatin Calcium
  • 17
    • 0242509092 scopus 로고    scopus 로고
    • Absolute oral bioavailability of rosuvastatin in healthy white adult male volunteers
    • Martin PD, Warwick MJ, Dane AL, et al. Absolute oral bioavailability of rosuvastatin in healthy white adult male volunteers. Clin Ther 2003;25:2553-63
    • (2003) Clin Ther , vol.25 , pp. 2553-2563
    • Martin, P.D.1    Warwick, M.J.2    Dane, A.L.3
  • 18
    • 42949162083 scopus 로고    scopus 로고
    • An evaluation of rosuvastatin: Pharmacokinetics, clinical efficacy and tolerability
    • Crouse JR III. An evaluation of rosuvastatin: Pharmacokinetics, clinical efficacy and tolerability. Expert Opin Drug Metab Toxicol 2008;4:287-304
    • (2008) Expert Opin Drug Metab Toxicol , vol.4 , pp. 287-304
    • Crouse III, J.R.1
  • 19
    • 0036432991 scopus 로고    scopus 로고
    • Pharmacodynamic effects and pharmacokinetics of a new hmg-coa reductase inhibitor, rosuvastatin, after morning or evening administration in healthy volunteers
    • Martin PD, Mitchell PD, Schneck DW. Pharmacodynamic effects and pharmacokinetics of a new HMG-CoA reductase inhibitor, rosuvastatin, after morning or evening administration in healthy volunteers. Br J Clin Pharmacol 2002;54:472-7
    • (2002) Br J Clin Pharmacol , vol.54 , pp. 472-477
    • Martin, P.D.1    Mitchell, P.D.2    Schneck, D.W.3
  • 20
    • 0344664550 scopus 로고    scopus 로고
    • Metabolism, excretion, and pharmacokinetics of rosuvastatin in healthy adult male volunteers
    • Martin PD, Warwick MJ, Dane AL, et al. Metabolism, excretion, and pharmacokinetics of rosuvastatin in healthy adult male volunteers. Clin Ther 2003;25:2822-35
    • (2003) Clin Ther , vol.25 , pp. 2822-2835
    • Martin, P.D.1    Warwick, M.J.2    Dane, A.L.3
  • 21
    • 2942705774 scopus 로고    scopus 로고
    • Safety of statins: Focus on clinical pharmacokinetics and drug interactions
    • Bellosta S, Paoletti R, Corsini A. Safety of statins: Focus on clinical pharmacokinetics and drug interactions. Circulation 2004;109:III50-7
    • (2004) Circulation , vol.109
    • Bellosta, S.1    Paoletti, R.2    Corsini, A.3
  • 23
    • 0036843479 scopus 로고    scopus 로고
    • Effects of fibrates on metabolism of statins in human hepatocytes
    • Prueksaritanont T, Tang C, Qiu Y, et al. Effects of fibrates on metabolism of statins in human hepatocytes. Drug Metab Dispos 2002;30:1280-7
    • (2002) Drug Metab Dispos , vol.30 , pp. 1280-1287
    • Prueksaritanont, T.1    Tang, C.2    Qiu, Y.3
  • 24
    • 0042531819 scopus 로고    scopus 로고
    • Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: Similarities and difference in the metabolism of pitavastatin in monkeys and humans
    • Yamada I, Fujino H, Shimada S, Kojima J. Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: Similarities and difference in the metabolism of pitavastatin in monkeys and humans. Xenobiotica 2003;33:789-803
    • (2003) Xenobiotica , vol.33 , pp. 789-803
    • Yamada, I.1    Fujino, H.2    Shimada, S.3    Kojima, J.4
  • 26
    • 0036786383 scopus 로고    scopus 로고
    • No effect of age or gender on the pharmacokinetics of rosuvastatin: A new HMG-CoA reductase inhibitor
    • Martin PD, Dane AL, Nwose OM, et al. No effect of age or gender on the pharmacokinetics of rosuvastatin: A new HMG-CoA reductase inhibitor. J Clin Pharmacol 2002;42:1116-21
    • (2002) J Clin Pharmacol , vol.42 , pp. 1116-1121
    • Martin, P.D.1    Dane, A.L.2    Nwose, O.M.3
  • 27
    • 53349153621 scopus 로고    scopus 로고
    • Population pharmacokinetics of rosuvastatin: Implications of renal impairment, race, and dyslipidaemia
    • Tzeng TB, Schneck DW, Birmingham BK, et al. Population pharmacokinetics of rosuvastatin: Implications of renal impairment, race, and dyslipidaemia. Curr Med Res Opin 2008;24:2575-85
    • (2008) Curr Med Res Opin , vol.24 , pp. 2575-2585
    • Tzeng, T.B.1    Schneck, D.W.2    Birmingham, B.K.3
  • 28
    • 71449097821 scopus 로고    scopus 로고
    • Pharmacokinetics of rosuvastatin in patients with end-stage kidney disease undergoing peritoneal dialysis
    • Bologa R, Levine D, Parker T, et al. Pharmacokinetics of rosuvastatin in patients with end-stage kidney disease undergoing peritoneal dialysis. Clin Nephrol 2009;72:437-41
    • (2009) Clin Nephrol , vol.72 , pp. 437-441
    • Bologa, R.1    Levine, D.2    Parker, T.3
  • 29
    • 84877012571 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic profile of rosuvastatin in patients with end-stage renal disease on chronic haemodialysis
    • Birmingham BK, Swan SK, Puchalski T, et al. Pharmacokinetic and pharmacodynamic profile of rosuvastatin in patients with end-stage renal disease on chronic haemodialysis. Clin Drug Investig 2013;33:233-41
    • (2013) Clin Drug Investig , vol.33 , pp. 233-241
    • Birmingham, B.K.1    Swan, S.K.2    Puchalski, T.3
  • 30
    • 63849163945 scopus 로고    scopus 로고
    • Rosuvastatin and cardiovascular events in patients undergoing hemodialysis
    • Fellstrom BC, Jardine AG, Schmieder RE, et al. Rosuvastatin and cardiovascular events in patients undergoing hemodialysis. N Engl J Med 2009;360:1395-407
    • (2009) N Engl J Med , vol.360 , pp. 1395-1407
    • Fellstrom, B.C.1    Jardine, A.G.2    Schmieder, R.E.3
  • 31
    • 84863778991 scopus 로고    scopus 로고
    • Comparison of the safety, tolerability, and pharmacokinetic profile of a single oral dose of pitavastatin 4 mg in adult subjects with severe renal impairment not on hemodialysis versus healthy adult subjects
    • Morgan RE, Campbell SE, Yu CY, et al. Comparison of the safety, tolerability, and pharmacokinetic profile of a single oral dose of pitavastatin 4 mg in adult subjects with severe renal impairment not on hemodialysis versus healthy adult subjects. J Cardiovasc Pharmacol 2012;60:42-8
    • (2012) J Cardiovasc Pharmacol , vol.60 , pp. 42-48
    • Morgan, R.E.1    Campbell, S.E.2    Yu, C.Y.3
  • 32
    • 28444444126 scopus 로고    scopus 로고
    • Effects of renal failure on drug transport and metabolism
    • Sun H, Frassetto L, Benet LZ. Effects of renal failure on drug transport and metabolism. Pharmacol Ther 2006;109:1-11
    • (2006) Pharmacol Ther , vol.109 , pp. 1-11
    • Sun, H.1    Frassetto, L.2    Benet, L.Z.3
  • 33
    • 51049095076 scopus 로고    scopus 로고
    • The effect of chronic renal failure on drug metabolism and transport
    • Dreisbach AW, Lertora JJ. The effect of chronic renal failure on drug metabolism and transport. Expert Opin Drug Metab Toxicol 2008;4:1065-74
    • (2008) Expert Opin Drug Metab Toxicol , vol.4 , pp. 1065-1074
    • Dreisbach, A.W.1    Lertora, J.J.2
  • 34
    • 0037300357 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of rosuvastatin in subjects with hepatic impairment
    • Simonson SG, Martin PD, Mitchell P, et al. Pharmacokinetics and pharmacodynamics of rosuvastatin in subjects with hepatic impairment. Eur J Clin Pharmacol 2003;58:669-75
    • (2003) Eur J Clin Pharmacol , vol.58 , pp. 669-675
    • Simonson, S.G.1    Martin, P.D.2    Mitchell, P.3
  • 35
    • 15244362340 scopus 로고    scopus 로고
    • Pharmacokinetics of pitavastatin in subjects with Child-Pugh A and B cirrhosis
    • Hui CK, Cheung BM, Lau GK. Pharmacokinetics of pitavastatin in subjects with Child-Pugh A and B cirrhosis. Br J Clin Pharmacol 2005;59:291-7
    • (2005) Br J Clin Pharmacol , vol.59 , pp. 291-297
    • Hui, C.K.1    Cheung, B.M.2    Lau, G.K.3
  • 36
    • 33644819092 scopus 로고    scopus 로고
    • Polymorphisms in four genes related to triglyceride and hdl-cholesterol levels in the general japanese population in 2000
    • Arai H, Yamamoto A, Matsuzawa Y, et al. Polymorphisms in four genes related to triglyceride and HDL-cholesterol levels in the general Japanese population in 2000. J Atheroscler Thromb 2005;12:240-50
    • (2005) J Atheroscler Thromb , vol.12 , pp. 240-250
    • Arai, H.1    Yamamoto, A.2    Matsuzawa, Y.3
  • 37
    • 0342467928 scopus 로고    scopus 로고
    • New therapies on the horizon
    • Brown WV. New therapies on the horizon. Am J Manag Care 2001;7:S148-51
    • (2001) Am J Manag Care , vol.7
    • Brown, W.V.1
  • 38
    • 0002123944 scopus 로고    scopus 로고
    • Selectivity of ZD4522 for inhibition of cholesterol synthesis in hepatic versus non-hepatic cells
    • Buckett L, Ballard P, Davidson R, et al. Selectivity of ZD4522 for inhibition of cholesterol synthesis in hepatic versus non-hepatic cells. Atherosclerosis 2000;151:41
    • (2000) Atherosclerosis , vol.151 , pp. 41
    • Buckett, L.1    Ballard, P.2    Davidson, R.3
  • 39
    • 47549096607 scopus 로고    scopus 로고
    • Same drug, different dosing: Differences in dosing for drugs approved in the united states, europe, and japan
    • Malinowski HJ, Westelinck A, Sato J, Ong T. Same drug, different dosing: Differences in dosing for drugs approved in the United States, Europe, and Japan. J Clin Pharmacol 2008;48:900-8
    • (2008) J Clin Pharmacol , vol.48 , pp. 900-908
    • Malinowski, H.J.1    Westelinck, A.2    Sato, J.3    Ong, T.4
  • 40
    • 25844458977 scopus 로고    scopus 로고
    • Rosuvastatin pharmacokinetics and pharmacogenetics in white and Asian subjects residing in the same environment
    • Lee E, Ryan S, Birmingham B, et al. Rosuvastatin pharmacokinetics and pharmacogenetics in white and Asian subjects residing in the same environment. Clin Pharmacol Ther 2005;78:330-41
    • (2005) Clin Pharmacol Ther , vol.78 , pp. 330-341
    • Lee, E.1    Ryan, S.2    Birmingham, B.3
  • 41
    • 25844440854 scopus 로고    scopus 로고
    • Ethnic differences in statin disposition
    • Tirona RG. Ethnic differences in statin disposition. Clin Pharmacol Ther 2005;78:311-16
    • (2005) Clin Pharmacol Ther , vol.78 , pp. 311-316
    • Tirona, R.G.1
  • 42
    • 84885602904 scopus 로고    scopus 로고
    • Do the lipid responses to rosuvastatin and atorvastatin differ between Chinese and Caucasians? Comparison of the DISCOVERY-Hong Kong study with other DISCOVERY studies
    • published online 1 May 2013; doi: Pii: S0167-5273 (13)00675-X. 10.1016/j. ijcard.2013.04.091
    • Hu M, Lui SS, Ko GT, Tomlinson B. Do the lipid responses to rosuvastatin and atorvastatin differ between Chinese and Caucasians? Comparison of the DISCOVERY-Hong Kong study with other DISCOVERY studies. Int J Cardiol 2013;published online 1 May 2013; doi: Pii: S0167-5273(13)00675-X. 10.1016/j. ijcard.2013.04.091
    • (2013) Int J Cardiol
    • Hu, M.1    Lui, S.S.2    Ko, G.T.3    Tomlinson, B.4
  • 43
    • 80054859153 scopus 로고    scopus 로고
    • Increased exposure levels of rosuvastatin, atorvastatin and simvastatin in Chinese and Japanese subjects: A class effect?
    • Birmingham BK, Azumaya CT, Wei C, et al. Increased exposure levels of rosuvastatin, atorvastatin and simvastatin in Chinese and Japanese subjects: A class effect? Clin Pharmacol Ther 2008;83:S15
    • (2008) Clin Pharmacol Ther , vol.83
    • Birmingham, B.K.1    Azumaya, C.T.2    Wei, C.3
  • 44
    • 80052484231 scopus 로고    scopus 로고
    • Comparison of the pharmacokinetics of pitavastatin by formulation and ethnic group: An open-label, single-dose, two-way crossover pharmacokinetic study in healthy Caucasian and Japanese men
    • Warrington S, Nagakawa S, Hounslow N. Comparison of the pharmacokinetics of pitavastatin by formulation and ethnic group: An open-label, single-dose, two-way crossover pharmacokinetic study in healthy Caucasian and Japanese men. Clin Drug Investig 2011;31:735-43
    • (2011) Clin Drug Investig , vol.31 , pp. 735-743
    • Warrington, S.1    Nagakawa, S.2    Hounslow, N.3
  • 45
    • 33646536542 scopus 로고    scopus 로고
    • Drug and bile acid transporters in rosuvastatin hepatic uptake: Function, expression, and pharmacogenetics
    • Ho RH, Tirona RG, Leake BF, et al. Drug and bile acid transporters in rosuvastatin hepatic uptake: Function, expression, and pharmacogenetics. Gastroenterology 2006;130:1793-806
    • (2006) Gastroenterology , vol.130 , pp. 1793-1806
    • Ho, R.H.1    Tirona, R.G.2    Leake, B.F.3
  • 46
    • 52949104006 scopus 로고    scopus 로고
    • Involvement of multiple transporters in the hepatobiliary transport of rosuvastatin
    • Kitamura S, Maeda K, Wang Y, Sugiyama Y. Involvement of multiple transporters in the hepatobiliary transport of rosuvastatin. Drug Metab Dispos 2008;36:2014-23
    • (2008) Drug Metab Dispos , vol.36 , pp. 2014-2023
    • Kitamura, S.1    Maeda, K.2    Wang, Y.3    Sugiyama, Y.4
  • 47
    • 4644364576 scopus 로고    scopus 로고
    • Contribution of oatp2 (oatp1b1) and oatp8 (oatp1b3) to the hepatic uptake of pitavastatin in humans
    • Hirano M, Maeda K, Shitara Y, Sugiyama Y. Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans. J Pharmacol Exp Ther 2004;311:139-46
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 139-146
    • Hirano, M.1    Maeda, K.2    Shitara, Y.3    Sugiyama, Y.4
  • 48
    • 23944475903 scopus 로고    scopus 로고
    • Involvement of bcrp (abcg2) in the biliary excretion of pitavastatin
    • Hirano M, Maeda K, Matsushima S, et al. Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin. Mol Pharmacol 2005;68:800-7
    • (2005) Mol Pharmacol , vol.68 , pp. 800-807
    • Hirano, M.1    Maeda, K.2    Matsushima, S.3
  • 49
    • 33645829284 scopus 로고    scopus 로고
    • ATP-dependent transport of rosuvastatin in membrane vesicles expressing breast cancer resistance protein
    • Huang L, Wang Y, Grimm S. ATP-dependent transport of rosuvastatin in membrane vesicles expressing breast cancer resistance protein. Drug Metab Dispos 2006;34:738-42
    • (2006) Drug Metab Dispos , vol.34 , pp. 738-742
    • Huang, L.1    Wang, Y.2    Grimm, S.3
  • 50
    • 78650183300 scopus 로고    scopus 로고
    • Differential effect of genetic variants of na(+)-Taurocholate co-Transporting polypeptide (ntcp) and organic anion-Transporting polypeptide 1b1 (oatp1b1) on the uptake of hmg-coa reductase inhibitors
    • Choi MK, Shin HJ, Choi YL, et al. Differential effect of genetic variants of Na(+)-Taurocholate co-Transporting polypeptide (NTCP) and organic anion-Transporting polypeptide 1B1 (OATP1B1) on the uptake of HMG-CoA reductase inhibitors. Xenobiotica 2011;41:24-34
    • (2011) Xenobiotica , vol.41 , pp. 24-34
    • Choi, M.K.1    Shin, H.J.2    Choi, Y.L.3
  • 51
    • 27544515516 scopus 로고    scopus 로고
    • Transporter-mediated influx and efflux mechanisms of pitavastatin, a new inhibitor of HMG-CoA reductase
    • Fujino H, Saito T, Ogawa S, Kojima J. Transporter-mediated influx and efflux mechanisms of pitavastatin, a new inhibitor of HMG-CoA reductase. J Pharm Pharmacol 2005;57:1305-11
    • (2005) J Pharm Pharmacol , vol.57 , pp. 1305-1311
    • Fujino, H.1    Saito, T.2    Ogawa, S.3    Kojima, J.4
  • 52
    • 79953901458 scopus 로고    scopus 로고
    • Organic anion transporting polypeptide 1B1: A genetically polymorphic transporter of major importance for hepatic drug uptake
    • Niemi M, Pasanen MK, Neuvonen PJ. Organic anion transporting polypeptide 1B1: A genetically polymorphic transporter of major importance for hepatic drug uptake. Pharmacol Rev 2011;63:157-81
    • (2011) Pharmacol Rev , vol.63 , pp. 157-181
    • Niemi, M.1    Pasanen, M.K.2    Neuvonen, P.J.3
  • 54
    • 72849141790 scopus 로고    scopus 로고
    • Transporter pharmacogenetics and statin toxicity
    • Niemi M. Transporter pharmacogenetics and statin toxicity. Clin Pharmacol Ther 2010;87:130-3
    • (2010) Clin Pharmacol Ther , vol.87 , pp. 130-133
    • Niemi, M.1
  • 55
    • 49949104757 scopus 로고    scopus 로고
    • SLCO1B1 variants and statin-induced myopathy-A genomewide study
    • Link E, Parish S, Armitage J, et al. SLCO1B1 variants and statin-induced myopathy-A genomewide study. N Engl J Med 2008;359:789-99
    • (2008) N Engl J Med , vol.359 , pp. 789-799
    • Link, E.1    Parish, S.2    Armitage, J.3
  • 56
    • 84890397957 scopus 로고    scopus 로고
    • Environmental and genetic risk factors for myopathy in chinese partifipants from hps2-Thrive
    • Available from
    • Hopewell JC, Offer A, Parish S, et al. Environmental and genetic risk factors for myopathy in Chinese partifipants from HPS2-THRIVE. European Society Cardiology. 2012. Available from: Http://www.thrivestudy.org/ ESC2012-THRIVE-myopathy-Abstract. pdf
    • (2012) European Society Cardiology
    • Hopewell, J.C.1    Offer, A.2    Parish, S.3
  • 57
    • 42149127614 scopus 로고    scopus 로고
    • The effect of SLCO1B1.*15 on the disposition of pravastatin and pitavastatin is substrate dependent: The contribution of transporting activity changes by SLCO1B1.15
    • Deng JW, Song IS, Shin HJ, et al. The effect of SLCO1B1.*15 on the disposition of pravastatin and pitavastatin is substrate dependent: The contribution of transporting activity changes by SLCO1B1.*15. Pharmacogenet Genomics 2008;18:424-33
    • (2008) Pharmacogenet Genomics , vol.18 , pp. 424-433
    • Deng, J.W.1    Song, I.S.2    Shin, H.J.3
  • 58
    • 25844530136 scopus 로고    scopus 로고
    • Effect of oatp1b1 (slco1b1) variant alleles on the pharmacokinetics of pitavastatin in healthy volunteers
    • Chung JY, Cho JY, Yu KS, et al. Effect of OATP1B1 (SLCO1B1) variant alleles on the pharmacokinetics of pitavastatin in healthy volunteers. Clin Pharmacol Ther 2005;78:342-50
    • (2005) Clin Pharmacol Ther , vol.78 , pp. 342-350
    • Chung, J.Y.1    Cho, J.Y.2    Yu, K.S.3
  • 59
    • 35448946484 scopus 로고    scopus 로고
    • Slco1b1 (oatp1b1, an uptake transporter) and abcg2 (bcrp, an efflux transporter) variant alleles and pharmacokinetics of pitavastatin in healthy volunteers
    • Ieiri I, Suwannakul S, Maeda K, et al. SLCO1B1 (OATP1B1, an uptake transporter) and ABCG2 (BCRP, an efflux transporter) variant alleles and pharmacokinetics of pitavastatin in healthy volunteers. Clin Pharmacol Ther 2007;82:541-7
    • (2007) Clin Pharmacol Ther , vol.82 , pp. 541-547
    • Ieiri, I.1    Suwannakul, S.2    Maeda, K.3
  • 60
    • 36148953896 scopus 로고    scopus 로고
    • Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin
    • Pasanen MK, Fredrikson H, Neuvonen PJ, Niemi M. Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin. Clin Pharmacol Ther 2007;82:726-33
    • (2007) Clin Pharmacol Ther , vol.82 , pp. 726-733
    • Pasanen, M.K.1    Fredrikson, H.2    Neuvonen, P.J.3    Niemi, M.4
  • 61
    • 38549159477 scopus 로고    scopus 로고
    • Influence of OATP1B1 genotype on the pharmacokinetics of rosuvastatin in Koreans
    • Choi JH, Lee MG, Cho JY, et al. Influence of OATP1B1 genotype on the pharmacokinetics of rosuvastatin in Koreans. Clin Pharmacol Ther 2008;83:251-7
    • (2008) Clin Pharmacol Ther , vol.83 , pp. 251-257
    • Choi, J.H.1    Lee, M.G.2    Cho, J.Y.3
  • 62
    • 75549088606 scopus 로고    scopus 로고
    • The influence of slco1b1 (oatp1b1) gene polymorphisms on response to statin therapy
    • Romaine SP, Bailey KM, Hall AS, Balmforth AJ. The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy. Pharmacogenomics J 2010;10:1-11
    • (2010) Pharmacogenomics J , vol.10 , pp. 1-11
    • Romaine, S.P.1    Bailey, K.M.2    Hall, A.S.3    Balmforth, A.J.4
  • 63
    • 79960148136 scopus 로고    scopus 로고
    • Impact of slco1b1 (oatp1b1) and abcg2 (bcrp) genetic polymorphisms and inhibition on ldl-c lowering and myopathy of statins
    • Generaux GT, Bonomo FM, Johnson M, Doan KM. Impact of SLCO1B1 (OATP1B1) and ABCG2 (BCRP) genetic polymorphisms and inhibition on LDL-C lowering and myopathy of statins. Xenobiotica 2011;41:639-51
    • (2011) Xenobiotica , vol.41 , pp. 639-651
    • Generaux, G.T.1    Bonomo, F.M.2    Johnson, M.3    Doan, K.M.4
  • 64
    • 67650753944 scopus 로고    scopus 로고
    • Genetic polymorphisms of uptake (oatp1b1, 1b3) and efflux (mrp2, bcrp) transporters: Implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs
    • Ieiri I, Higuchi S, Sugiyama Y. Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: Implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs. Expert Opin Drug Metab Toxicol 2009;5:703-29
    • (2009) Expert Opin Drug Metab Toxicol , vol.5 , pp. 703-729
    • Ieiri, I.1    Higuchi, S.2    Sugiyama, Y.3
  • 65
    • 77957237434 scopus 로고    scopus 로고
    • Pharmacogenetic analysis of lipid responses to rosuvastatin in chinese patients
    • Hu M, Lui SS, Mak VW, et al. Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients. Pharmacogenet Genomics 2010;20:634-7
    • (2010) Pharmacogenet Genomics , vol.20 , pp. 634-637
    • Hu, M.1    Lui, S.S.2    Mak, V.W.3
  • 66
    • 69549111453 scopus 로고    scopus 로고
    • Comprehensive whole-genome and candidate gene analysis for response to statin therapy in the treating to new targets (tnt) cohort
    • Thompson JF, Hyde CL, Wood LS, et al. Comprehensive whole-genome and candidate gene analysis for response to statin therapy in the Treating to New Targets (TNT) cohort. Circ Cardiovasc Genet 2009;2:173-81
    • (2009) Circ Cardiovasc Genet , vol.2 , pp. 173-181
    • Thompson, J.F.1    Hyde, C.L.2    Wood, L.S.3
  • 67
    • 84860271201 scopus 로고    scopus 로고
    • Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: Importance of Lp(a
    • Deshmukh HA, Colhoun HM, Johnson T, et al. Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: Importance of Lp(a). J Lipid Res 2012;53:1000-11
    • (2012) J Lipid Res , vol.53 , pp. 1000-1011
    • Deshmukh, H.A.1    Colhoun, H.M.2    Johnson, T.3
  • 68
    • 84875983072 scopus 로고    scopus 로고
    • Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the heart protection study
    • Hopewell JC, Parish S, Offer A, et al. Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study. Eur Heart J 2013;34:982-92
    • (2013) Eur Heart J , vol.34 , pp. 982-992
    • Hopewell, J.C.1    Parish, S.2    Offer, A.3
  • 69
    • 84860798384 scopus 로고    scopus 로고
    • Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: The justification for the use of statins in prevention: An intervention trial evaluating rosuvastatin (jupiter) trial
    • Chasman DI, Giulianini F, MacFadyen J, et al. Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: The Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) trial. Circ Cardiovasc Genet 2012;5:257-64
    • (2012) Circ Cardiovasc Genet , vol.5 , pp. 257-264
    • Chasman, D.I.1    Giulianini, F.2    MacFadyen, J.3
  • 70
    • 84865979524 scopus 로고    scopus 로고
    • Organic anion-Transporting polypeptides 1a/1b control the hepatic uptake of pravastatin in mice
    • Iusuf D, Sparidans RW, van Esch A, et al. Organic anion-Transporting polypeptides 1a/1b control the hepatic uptake of pravastatin in mice. Mol Pharm 2012;9:2497-504
    • (2012) Mol Pharm , vol.9 , pp. 2497-2504
    • Iusuf, D.1    Sparidans, R.W.2    Van Esch, A.3
  • 71
    • 84876520840 scopus 로고    scopus 로고
    • Murine Oatp1a/1b uptake transporters control rosuvastatin systemic exposure without affecting its apparent liver exposure
    • Iusuf D, van Esch A, Hobbs M, et al. Murine Oatp1a/1b uptake transporters control rosuvastatin systemic exposure without affecting its apparent liver exposure. Mol Pharmacol 2013;83:919-29
    • (2013) Mol Pharmacol , vol.83 , pp. 919-929
    • Iusuf, D.1    Van Esch, A.2    Hobbs, M.3
  • 72
    • 59649130318 scopus 로고    scopus 로고
    • Physiologically based pharmacokinetic modeling to predict transporter-mediated clearance and distribution of pravastatin in humans
    • Watanabe T, Kusuhara H, Maeda K, et al. Physiologically based pharmacokinetic modeling to predict transporter-mediated clearance and distribution of pravastatin in humans. J Pharmacol Exp Ther 2009;328:652-62
    • (2009) J Pharmacol Exp Ther , vol.328 , pp. 652-662
    • Watanabe, T.1    Kusuhara, H.2    Maeda, K.3
  • 73
    • 2042469487 scopus 로고    scopus 로고
    • Evidence for inverse effects of oatp-c (slc21a6) 5 and 1b haplotypes on pravastatin kinetics
    • Mwinyi J, Johne A, Bauer S, et al. Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics. Clin Pharmacol Ther 2004;75:415-21
    • (2004) Clin Pharmacol Ther , vol.75 , pp. 415-421
    • Mwinyi, J.1    Johne, A.2    Bauer, S.3
  • 74
    • 74349126111 scopus 로고    scopus 로고
    • OATP1B1 388A > G polymorphism and pharmacokinetics of pitavastatin in Chinese healthy volunteers
    • Wen J, Xiong Y. OATP1B1 388A > G polymorphism and pharmacokinetics of pitavastatin in Chinese healthy volunteers. J Clin Pharm Ther 2010;35:99-104
    • (2010) J Clin Pharm Ther , vol.35 , pp. 99-104
    • Wen, J.1    Xiong, Y.2
  • 75
    • 84876765967 scopus 로고    scopus 로고
    • Effects of grapefruit juice and SLCO1B1 388A G polymorphism on the pharmacokinetics of pitavastatin
    • Hu M, Mak VW, Yin OQ, et al. Effects of grapefruit juice and SLCO1B1 388A G polymorphism on the pharmacokinetics of pitavastatin. Drug Metab Pharmacokinet 2013;28:104-8
    • (2013) Drug Metab Pharmacokinet , vol.28 , pp. 104-108
    • Hu, M.1    Mak, V.W.2    Yin, O.Q.3
  • 76
    • 78650469299 scopus 로고    scopus 로고
    • The ABCG2 transporter and its relations with the pharmacokinetics, drug interaction and lipid-lowering effects of statins
    • Hu M, To KK, Mak VW, Tomlinson B. The ABCG2 transporter and its relations with the pharmacokinetics, drug interaction and lipid-lowering effects of statins. Expert Opin Drug Metab Toxicol 2011;7:49-62
    • (2011) Expert Opin Drug Metab Toxicol , vol.7 , pp. 49-62
    • Hu, M.1    To, K.K.2    Mak, V.W.3    Tomlinson, B.4
  • 77
    • 33747884712 scopus 로고    scopus 로고
    • Role of bcrp 421c > a polymorphism on rosuvastatin pharmacokinetics in healthy chinese males
    • Zhang W, Yu BN, He YJ, et al. Role of BCRP 421C > A polymorphism on rosuvastatin pharmacokinetics in healthy Chinese males. Clin Chim Acta 2006;373:99-103
    • (2006) Clin Chim Acta , vol.373 , pp. 99-103
    • Zhang, W.1    Yu, B.N.2    He, Y.J.3
  • 78
    • 67651172794 scopus 로고    scopus 로고
    • ABCG2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin
    • Keskitalo JE, Zolk O, Fromm MF, et al. ABCG2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin. Clin Pharmacol Ther 2009;86:197-203
    • (2009) Clin Pharmacol Ther , vol.86 , pp. 197-203
    • Keskitalo, J.E.1    Zolk, O.2    Fromm, M.F.3
  • 79
    • 70649110001 scopus 로고    scopus 로고
    • Different effects of the abcg2 c.421c >a snp on the pharmacokinetics of fluvastatin, pravastatin and simvastatin
    • Keskitalo JE, Pasanen MK, Neuvonen PJ, Niemi M. Different effects of the ABCG2 c.421C > A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin. Pharmacogenomics 2009;10:1617-24
    • (2009) Pharmacogenomics , vol.10 , pp. 1617-1624
    • Keskitalo, J.E.1    Pasanen, M.K.2    Neuvonen, P.J.3    Niemi, M.4
  • 80
    • 84879388830 scopus 로고    scopus 로고
    • Impact of abcc2 abcg2 and slco1b1 polymorphisms on the pharmacokinetics of pitavastatin in humans
    • Oh ES, Kim CO, Cho SK, et al. Impact of ABCC2, ABCG2 and SLCO1B1 polymorphisms on the pharmacokinetics of pitavastatin in humans. Drug Metab Pharmacokinet 2013;28:196-202
    • (2013) Drug Metab Pharmacokinet , vol.28 , pp. 196-202
    • Oh, E.S.1    Kim, C.O.2    Cho, S.K.3
  • 81
    • 77951499767 scopus 로고    scopus 로고
    • ABCG2 polymorphism is associated with the low-density lipoprotein cholesterol response to rosuvastatin
    • Tomlinson B, Hu M, Lee VW, et al. ABCG2 polymorphism is associated with the low-density lipoprotein cholesterol response to rosuvastatin. Clin Pharmacol Ther 2010;87:558-62
    • (2010) Clin Pharmacol Ther , vol.87 , pp. 558-562
    • Tomlinson, B.1    Hu, M.2    Lee, V.W.3
  • 82
    • 68449085764 scopus 로고    scopus 로고
    • No significant effect of ABCB1 haplotypes on the pharmacokinetics of fluvastatin, pravastatin, lovastatin, and rosuvastatin
    • Keskitalo JE, Kurkinen KJ, Neuvonen M, et al. No significant effect of ABCB1 haplotypes on the pharmacokinetics of fluvastatin, pravastatin, lovastatin, and rosuvastatin. Br J Clin Pharmacol 2009;68:207-13
    • (2009) Br J Clin Pharmacol , vol.68 , pp. 207-213
    • Keskitalo, J.E.1    Kurkinen, K.J.2    Neuvonen, M.3
  • 83
    • 84874851195 scopus 로고    scopus 로고
    • CYP2C9.*3(1075A > C), ABCB1 and SLCO1B1 genetic polymorphisms and gender are determinants of inter-subject variability in pitavastatin pharmacokinetics
    • Zhou Q, Chen QX, Ruan ZR, et al. CYP2C9.*3(1075A > C), ABCB1 and SLCO1B1 genetic polymorphisms and gender are determinants of inter-subject variability in pitavastatin pharmacokinetics. Pharmazie 2013;68:187-94
    • (2013) Pharmazie , vol.68 , pp. 187-194
    • Zhou, Q.1    Chen, Q.X.2    Ruan, Z.R.3
  • 84
    • 84875830097 scopus 로고    scopus 로고
    • Abcb1 gene polymorphisms abcb1 haplotypes and abcg2 c.421c >a are determinants of inter-subject variability in rosuvastatin pharmacokinetics
    • Zhou Q, Ruan ZR, Yuan H, et al. ABCB1 gene polymorphisms, ABCB1 haplotypes and ABCG2 c.421c > A are determinants of inter-subject variability in rosuvastatin pharmacokinetics. Pharmazie 2013;68:129-34
    • (2013) Pharmazie , vol.68 , pp. 129-134
    • Zhou, Q.1    Ruan, Z.R.2    Yuan, H.3
  • 85
    • 84878241152 scopus 로고    scopus 로고
    • Genetic variation in the ABCC2 gene is associated with dose decreases or switches to other cholesterol-lowering drugs during simvastatin and atorvastatin therapy
    • Becker ML, Elens LL, Visser LE, et al. Genetic variation in the ABCC2 gene is associated with dose decreases or switches to other cholesterol-lowering drugs during simvastatin and atorvastatin therapy. Pharmacogenomics J 2013;13:251-6
    • (2013) Pharmacogenomics J , vol.13 , pp. 251-256
    • Becker, M.L.1    Elens, L.L.2    Visser, L.E.3
  • 86
    • 84882247785 scopus 로고    scopus 로고
    • Effects of polymorphisms in ABCG2, SLCO1B1, SLC10A1 and CYP2C9/19 on plasma concentrations of rosuvastatin and lipid response in Chinese patients
    • Lee HK, Hu M, Lui S, et al. Effects of polymorphisms in ABCG2, SLCO1B1, SLC10A1 and CYP2C9/19 on plasma concentrations of rosuvastatin and lipid response in Chinese patients. Pharmacogenomics 2013;14:1283-94
    • (2013) Pharmacogenomics , vol.14 , pp. 1283-1294
    • Lee, H.K.1    Hu, M.2    Lui, S.3
  • 87
    • 84884507686 scopus 로고    scopus 로고
    • Clinical and pharmacogenetic predictors of circulating atorvastatin and rosuvastatin concentration in routine clinical care
    • Degorter MK, Tirona RG, Schwarz UI, et al. Clinical and Pharmacogenetic Predictors of Circulating Atorvastatin and Rosuvastatin Concentration in Routine Clinical Care. Circ Cardiovasc Genet 2013;6:400-8
    • (2013) Circ Cardiovasc Genet , vol.6 , pp. 400-408
    • Degorter, M.K.1    Tirona, R.G.2    Schwarz, U.I.3
  • 88
    • 35748962429 scopus 로고    scopus 로고
    • The safety of statins in clinical practice
    • Armitage J. The safety of statins in clinical practice. Lancet 2007;370:1781-90
    • (2007) Lancet , vol.370 , pp. 1781-1790
    • Armitage, J.1
  • 89
    • 84867773207 scopus 로고    scopus 로고
    • Statin drug interactions and related adverse reactions
    • Bellosta S, Corsini A. Statin drug interactions and related adverse reactions. Expert Opin Drug Saf 2012;11:933-46
    • (2012) Expert Opin Drug Saf , vol.11 , pp. 933-946
    • Bellosta, S.1    Corsini, A.2
  • 90
    • 33645868967 scopus 로고    scopus 로고
    • Statin safety and drug interactions: Clinical implications
    • Bottorff MB. Statin safety and drug interactions: Clinical implications. Am J Cardiol 2006;97:27C-31C
    • (2006) Am J Cardiol , vol.97
    • Bottorff, M.B.1
  • 91
    • 77649135512 scopus 로고    scopus 로고
    • Drug interactions with hmg-coa reductase inhibitors (statins): The importance of cyp enzymes, transporters and pharmacogenetics
    • Neuvonen PJ. Drug interactions with HMG-CoA reductase inhibitors (statins): The importance of CYP enzymes, transporters and pharmacogenetics. Curr Opin Investig Drugs 2010;11:323-32
    • (2010) Curr Opin Investig Drugs , vol.11 , pp. 323-332
    • Neuvonen, P.J.1
  • 92
    • 84873249294 scopus 로고    scopus 로고
    • Case report of exercise and statin-fibrate combination therapy-caused myopathy in a patient with metabolic syndrome: Contradictions between the two main therapeutic pathways
    • Laszlo A, Kalabay L, Nemcsik J. Case report of exercise and statin-fibrate combination therapy-caused myopathy in a patient with metabolic syndrome: Contradictions between the two main therapeutic pathways. BMC Res Notes 2013;6:52
    • (2013) BMC Res Notes , vol.6 , pp. 52
    • Laszlo, A.1    Kalabay, L.2    Nemcsik, J.3
  • 93
    • 33845420011 scopus 로고    scopus 로고
    • Drug interactions with lipid-lowering drugs: Mechanisms and clinical relevance
    • Neuvonen PJ, Niemi M, Backman JT. Drug interactions with lipid-lowering drugs: Mechanisms and clinical relevance. Clin Pharmacol Ther 2006;80:565-81
    • (2006) Clin Pharmacol Ther , vol.80 , pp. 565-581
    • Neuvonen, P.J.1    Niemi, M.2    Backman, J.T.3
  • 94
    • 84881414412 scopus 로고    scopus 로고
    • Drug-drug interactions between hmg-coa reductase inhibitors (statins) and antiviral protease inhibitors
    • published Online 24 May 2013 doi: 10.1007/s40262-013-0075-4
    • Chauvin B, Drouot S, Barrail-Tran A, Taburet AM. Drug-drug interactions between hmg-coa reductase inhibitors (statins) and antiviral protease inhibitors. Clin Pharmacokinet 2013;published online 24 May 2013; doi: 10.1007/s40262-013-0075-4
    • (2013) Clin Pharmacokinet
    • Chauvin, B.1    Drouot, S.2    Barrail-Tran, A.3    Taburet, A.M.4
  • 95
    • 79960400093 scopus 로고    scopus 로고
    • Drug-drug interactions with statins: Will pitavastatin overcome the statins' Achilles' heel
    • Corsini A, Ceska R. Drug-drug interactions with statins: Will pitavastatin overcome the statins' Achilles' heel? Curr Med Res Opin 2011;27:1551-62
    • (2011) Curr Med Res Opin , vol.27 , pp. 1551-1562
    • Corsini, A.1    Ceska, R.2
  • 96
  • 97
    • 79960065080 scopus 로고    scopus 로고
    • Pitavastatin: Finding its place in therapy
    • Ose L. Pitavastatin: Finding its place in therapy. Ther Adv Chronic Dis 2011;2:101-17
    • (2011) Ther Adv Chronic Dis , vol.2 , pp. 101-117
    • Ose, L.1
  • 98
    • 77149180421 scopus 로고    scopus 로고
    • Rosuvastatin-Associated adverse effects and drug-drug interactions in the clinical setting of dyslipidemia
    • Kostapanos MS, Milionis HJ, Elisaf MS. Rosuvastatin-Associated adverse effects and drug-drug interactions in the clinical setting of dyslipidemia. Am J Cardiovasc Drugs 2010;10:11-28
    • (2010) Am J Cardiovasc Drugs , vol.10 , pp. 11-28
    • Kostapanos, M.S.1    Milionis, H.J.2    Elisaf, M.S.3
  • 99
    • 84874040358 scopus 로고    scopus 로고
    • Drug-drug interactions between rosuvastatin and oral antidiabetic drugs occurring at the level of oatp1b1
    • van de Steeg E, Greupink R, Schreurs M, et al. Drug-drug interactions between rosuvastatin and oral antidiabetic drugs occurring at the level of OATP1B1. Drug Metab Dispos 2013;41:592-601
    • (2013) Drug Metab Dispos , vol.41 , pp. 592-601
    • Van De Steeg, E.1    Greupink, R.2    Schreurs, M.3
  • 100
    • 84866018277 scopus 로고    scopus 로고
    • The role of oatp1b1 and bcrp in pharmacokinetics and ddi of novel statins
    • Hua WJ, Hua WX, Fang HJ. The role of OATP1B1 and BCRP in pharmacokinetics and DDI of novel statins. Cardiovasc Ther 2012;30:e234-41
    • (2012) Cardiovasc Ther , vol.30
    • Hua, W.J.1    Hua, W.X.2    Fang, H.J.3
  • 101
    • 49149092361 scopus 로고    scopus 로고
    • Statin-drug interactions: Not a class effect
    • Frishman WH, Horn J. Statin-drug interactions: Not a class effect. Cardiol Rev 2008;16:205-12
    • (2008) Cardiol Rev , vol.16 , pp. 205-212
    • Frishman, W.H.1    Horn, J.2
  • 102
    • 78649482869 scopus 로고    scopus 로고
    • Drug-drug interactions in the treatment of HIV infection: Focus on pharmacokinetic enhancement through CYP3A inhibition
    • Josephson F. Drug-drug interactions in the treatment of HIV infection: Focus on pharmacokinetic enhancement through CYP3A inhibition. J Intern Med 2010;268:530-9
    • (2010) J Intern Med , vol.268 , pp. 530-539
    • Josephson, F.1
  • 103
    • 0031847115 scopus 로고    scopus 로고
    • Effect of itraconazole on the pharmacokinetics of atorvastatin
    • Kantola T, Kivisto KT, Neuvonen PJ. Effect of itraconazole on the pharmacokinetics of atorvastatin. Clin Pharmacol Ther 1998;64:58-65
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 58-65
    • Kantola, T.1    Kivisto, K.T.2    Neuvonen, P.J.3
  • 104
    • 0037239230 scopus 로고    scopus 로고
    • Lack of effect of ketoconazole on the pharmacokinetics of rosuvastatin in healthy subjects
    • Cooper KJ, Martin PD, Dane AL, et al. Lack of effect of ketoconazole on the pharmacokinetics of rosuvastatin in healthy subjects. Br J Clin Pharmacol 2003;55:94-9
    • (2003) Br J Clin Pharmacol , vol.55 , pp. 94-99
    • Cooper, K.J.1    Martin, P.D.2    Dane, A.L.3
  • 105
    • 0344453812 scopus 로고    scopus 로고
    • Effect of itraconazole on the pharmacokinetics of rosuvastatin
    • Cooper KJ, Martin PD, Dane AL, et al. Effect of itraconazole on the pharmacokinetics of rosuvastatin. Clin Pharmacol Ther 2003;73:322-9
    • (2003) Clin Pharmacol Ther , vol.73 , pp. 322-329
    • Cooper, K.J.1    Martin, P.D.2    Dane, A.L.3
  • 106
    • 0036451138 scopus 로고    scopus 로고
    • The effect of fluconazole on the pharmacokinetics of rosuvastatin
    • Cooper KJ, Martin PD, Dane AL, et al. The effect of fluconazole on the pharmacokinetics of rosuvastatin. Eur J Clin Pharmacol 2002;58:527-31
    • (2002) Eur J Clin Pharmacol , vol.58 , pp. 527-531
    • Cooper, K.J.1    Martin, P.D.2    Dane, A.L.3
  • 107
    • 0037040378 scopus 로고    scopus 로고
    • Pharmacokinetic interactions between protease inhibitors and statins in HIV seronegative volunteers: ACTG Study A5047
    • Fichtenbaum CJ, Gerber JG, Rosenkranz SL, et al. Pharmacokinetic interactions between protease inhibitors and statins in HIV seronegative volunteers: ACTG Study A5047. AIDS 2002;16:569-77
    • (2002) AIDS , vol.16 , pp. 569-577
    • Fichtenbaum, C.J.1    Gerber, J.G.2    Rosenkranz, S.L.3
  • 108
    • 84861830855 scopus 로고    scopus 로고
    • Steady-state pharmacokinetic interactions of darunavir/ritonavir with lipid-lowering agent rosuvastatin
    • Samineni D, Desai PB, Sallans L, Fichtenbaum CJ. Steady-state pharmacokinetic interactions of darunavir/ritonavir with lipid-lowering agent rosuvastatin. J Clin Pharmacol 2012;52:922-31
    • (2012) J Clin Pharmacol , vol.52 , pp. 922-931
    • Samineni, D.1    Desai, P.B.2    Sallans, L.3    Fichtenbaum, C.J.4
  • 109
    • 84862136276 scopus 로고    scopus 로고
    • Effects of steady-state lopinavir/ ritonavir on the pharmacokinetics of pitavastatin in healthy adult volunteers
    • Morgan RE, Campbell SE, Suehira K, et al. Effects of steady-state lopinavir/ ritonavir on the pharmacokinetics of pitavastatin in healthy adult volunteers. J Acquir Immune Defic Syndr 2012;60:158-64
    • (2012) J Acquir Immune Defic Syndr , vol.60 , pp. 158-164
    • Morgan, R.E.1    Campbell, S.E.2    Suehira, K.3
  • 110
    • 0038130937 scopus 로고    scopus 로고
    • The effect of erythromycin on the pharmacokinetics of rosuvastatin
    • Cooper KJ, Martin PD, Dane AL, et al. The effect of erythromycin on the pharmacokinetics of rosuvastatin. Eur J Clin Pharmacol 2003;59:51-6
    • (2003) Eur J Clin Pharmacol , vol.59 , pp. 51-56
    • Cooper, K.J.1    Martin, P.D.2    Dane, A.L.3
  • 111
    • 18144386137 scopus 로고    scopus 로고
    • Statins' dosage in patients with renal failure and cyclosporine drug-drug interactions in transplant recipient patients
    • Launay-Vacher V, Izzedine H, Deray G. Statins' dosage in patients with renal failure and cyclosporine drug-drug interactions in transplant recipient patients. Int J Cardiol 2005;101:9-17
    • (2005) Int J Cardiol , vol.101 , pp. 9-17
    • Launay-Vacher, V.1    Izzedine, H.2    Deray, G.3
  • 112
    • 3542992126 scopus 로고    scopus 로고
    • Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine
    • Simonson SG, Raza A, Martin PD, et al. Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine. Clin Pharmacol Ther 2004;76:167-77
    • (2004) Clin Pharmacol Ther , vol.76 , pp. 167-177
    • Simonson, S.G.1    Raza, A.2    Martin, P.D.3
  • 113
    • 12644251055 scopus 로고    scopus 로고
    • Accumulation of lovastatin, but not pravastatin, in the blood of cyclosporine-Treated kidney graft patients after multiple doses
    • Olbricht C, Wanner C, Eisenhauer T, et al. Accumulation of lovastatin, but not pravastatin, in the blood of cyclosporine-Treated kidney graft patients after multiple doses. Clin Pharmacol Ther 1997;62:311-21
    • (1997) Clin Pharmacol Ther , vol.62 , pp. 311-321
    • Olbricht, C.1    Wanner, C.2    Eisenhauer, T.3
  • 114
    • 3242789902 scopus 로고    scopus 로고
    • The drug-drug interactions of pitavastatin (NK-104), a novel HMG-CoA reductase inhibitor and cyclosporine
    • Hasunuma T, Nakamura M, Yachi T, et al. The drug-drug interactions of pitavastatin (NK-104), a novel HMG-CoA reductase inhibitor and cyclosporine. J Clin Ther Med 2003;19:381-9
    • (2003) J Clin Ther Med , vol.19 , pp. 381-389
    • Hasunuma, T.1    Nakamura, M.2    Yachi, T.3
  • 115
    • 27744605739 scopus 로고    scopus 로고
    • Pharmacokinetic interactions between statins and fibrates
    • discussion 34K-35K
    • Corsini A, Bellosta S, Davidson MH. Pharmacokinetic interactions between statins and fibrates. Am J Cardiol 2005;96:44K-9K; discussion 34K-35K
    • (2005) Am J Cardiol , vol.96
    • Corsini, A.1    Bellosta, S.2    Davidson, M.H.3
  • 116
    • 70349334010 scopus 로고    scopus 로고
    • Myopathy with statin-fibrate combination therapy: Clinical considerations
    • Jacobson TA. Myopathy with statin-fibrate combination therapy: Clinical considerations. Nat Rev Endocrinol 2009;5:507-18
    • (2009) Nat Rev Endocrinol , vol.5 , pp. 507-518
    • Jacobson, T.A.1
  • 117
    • 71349086893 scopus 로고    scopus 로고
    • Rhabdomyolysis associated with fibrate therapy: Review of 76 published cases and a new case report
    • Wu J, Song Y, Li H, Chen J. Rhabdomyolysis associated with fibrate therapy: Review of 76 published cases and a new case report. Eur J Clin Pharmacol 2009;65:1169-74
    • (2009) Eur J Clin Pharmacol , vol.65 , pp. 1169-1174
    • Wu, J.1    Song, Y.2    Li, H.3    Chen, J.4
  • 118
    • 11144354934 scopus 로고    scopus 로고
    • The effect of gemfibrozil on the pharmacokinetics of rosuvastatin
    • Schneck DW, Birmingham BK, Zalikowski JA, et al. The effect of gemfibrozil on the pharmacokinetics of rosuvastatin. Clin Pharmacol Ther 2004;75:455-63
    • (2004) Clin Pharmacol Ther , vol.75 , pp. 455-463
    • Schneck, D.W.1    Birmingham, B.K.2    Zalikowski, J.A.3
  • 119
    • 3242695305 scopus 로고    scopus 로고
    • Effect of gemfibrozil on the metabolism of pitavastatin-determining the best animal model for human CYP and UGT activities
    • Fujino H, Saito T, Tsunenari Y, Kojima J. Effect of gemfibrozil on the metabolism of pitavastatin-determining the best animal model for human CYP and UGT activities. Drug Metabol Drug Interact 2004;20:25-42
    • (2004) Drug Metabol Drug Interact , vol.20 , pp. 25-42
    • Fujino, H.1    Saito, T.2    Tsunenari, Y.3    Kojima, J.4
  • 120
    • 0031954328 scopus 로고    scopus 로고
    • Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid
    • Kantola T, Kivisto KT, Neuvonen PJ. Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid. Clin Pharmacol Ther 1998;63:397-402
    • (1998) Clin Pharmacol Ther , vol.63 , pp. 397-402
    • Kantola, T.1    Kivisto, K.T.2    Neuvonen, P.J.3
  • 121
    • 0031741901 scopus 로고    scopus 로고
    • Grapefruit juice-simvastatin interaction: Effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors
    • Lilja JJ, Kivisto KT, Neuvonen PJ. Grapefruit juice-simvastatin interaction: Effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors. Clin Pharmacol Ther 1998;64:477-83
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 477-483
    • Lilja, J.J.1    Kivisto, K.T.2    Neuvonen, P.J.3
  • 122
    • 0242645646 scopus 로고    scopus 로고
    • Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin
    • Lilja JJ, Kivisto KT, Neuvonen PJ. Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin. Clin Pharmacol Ther 1999;66:118-27
    • (1999) Clin Pharmacol Ther , vol.66 , pp. 118-127
    • Lilja, J.J.1    Kivisto, K.T.2    Neuvonen, P.J.3
  • 123
    • 0032865554 scopus 로고    scopus 로고
    • Inhibition of the CYP3A4-mediated metabolism and P-glycoprotein-mediated transport of the HIV-1 protease inhibitor saquinavir by grapefruit juice components
    • Eagling VA, Profit L, Back DJ. Inhibition of the CYP3A4-mediated metabolism and P-glycoprotein-mediated transport of the HIV-1 protease inhibitor saquinavir by grapefruit juice components. Br J Clin Pharmacol 1999;48:543-52
    • (1999) Br J Clin Pharmacol , vol.48 , pp. 543-552
    • Eagling, V.A.1    Profit, L.2    Back, D.J.3
  • 124
    • 84864277039 scopus 로고    scopus 로고
    • Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects
    • Rebello S, Zhao S, Hariry S, et al. Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects. Eur J Clin Pharmacol 2012;68:697-708
    • (2012) Eur J Clin Pharmacol , vol.68 , pp. 697-708
    • Rebello, S.1    Zhao, S.2    Hariry, S.3
  • 125
    • 79960116359 scopus 로고    scopus 로고
    • Differential effect of grapefruit juice on intestinal absorption of statins due to inhibition of organic anion transporting polypeptide and/or P-glycoprotein
    • Shirasaka Y, Suzuki K, Nakanishi T, Tamai I. Differential effect of grapefruit juice on intestinal absorption of statins due to inhibition of organic anion transporting polypeptide and/or P-glycoprotein. J Pharm Sci 2011;100:3843-53
    • (2011) J Pharm Sci , vol.100 , pp. 3843-3853
    • Shirasaka, Y.1    Suzuki, K.2    Nakanishi, T.3    Tamai, I.4
  • 126
    • 27444434929 scopus 로고    scopus 로고
    • Effects of grapefruit juice on the pharmacokinetics of pitavastatin and atorvastatin
    • Ando H, Tsuruoka S, Yanagihara H, et al. Effects of grapefruit juice on the pharmacokinetics of pitavastatin and atorvastatin. Br J Clin Pharmacol 2005;60:494-7
    • (2005) Br J Clin Pharmacol , vol.60 , pp. 494-497
    • Ando, H.1    Tsuruoka, S.2    Yanagihara, H.3
  • 127
    • 1942423683 scopus 로고    scopus 로고
    • Effects of grapefruit juice on pharmacokinetics of atorvastatin and pravastatin in Japanese
    • Fukazawa I, Uchida N, Uchida E, Yasuhara H. Effects of grapefruit juice on pharmacokinetics of atorvastatin and pravastatin in Japanese. Br J Clin Pharmacol 2004;57:448-55
    • (2004) Br J Clin Pharmacol , vol.57 , pp. 448-455
    • Fukazawa, I.1    Uchida, N.2    Uchida, E.3    Yasuhara, H.4
  • 128
    • 33846571368 scopus 로고    scopus 로고
    • Effect of OATP1B transporter inhibition on the pharmacokinetics of atorvastatin in healthy volunteers
    • Lau YY, Huang Y, Frassetto L, Benet LZ. Effect of OATP1B transporter inhibition on the pharmacokinetics of atorvastatin in healthy volunteers. Clin Pharmacol Ther 2007;81:194-204
    • (2007) Clin Pharmacol Ther , vol.81 , pp. 194-204
    • Lau, Y.Y.1    Huang, Y.2    Frassetto, L.3    Benet, L.Z.4
  • 129
    • 0036293982 scopus 로고    scopus 로고
    • Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver
    • Vavricka SR, Van Montfoort J, Ha HR, et al. Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver. Hepatology 2002;36:164-72
    • (2002) Hepatology , vol.36 , pp. 164-172
    • Vavricka, S.R.1    Van Montfoort, J.2    Ha, H.R.3
  • 130
    • 28444481386 scopus 로고    scopus 로고
    • Development of a fluorescence-based assay for screening of modulators of human organic anion transporter 1B3 (OATP1B3
    • Baldes C, Koenig P, Neumann D, et al. Development of a fluorescence-based assay for screening of modulators of human organic anion transporter 1B3 (OATP1B3). Eur J Pharm Biopharm 2006;62:39-43
    • (2006) Eur J Pharm Biopharm , vol.62 , pp. 39-43
    • Baldes, C.1    Koenig, P.2    Neumann, D.3
  • 131
    • 0034527327 scopus 로고    scopus 로고
    • Rifampin greatly reduces plasma simvastatin and simvastatin acid concentrations
    • Kyrklund C, Backman JT, Kivisto KT, et al. Rifampin greatly reduces plasma simvastatin and simvastatin acid concentrations. Clin Pharmacol Ther 2000;68:592-7
    • (2000) Clin Pharmacol Ther , vol.68 , pp. 592-597
    • Kyrklund, C.1    Backman, J.T.2    Kivisto, K.T.3
  • 132
    • 23444452547 scopus 로고    scopus 로고
    • Rifampin markedly decreases and gemfibrozil increases the plasma concentrations of atorvastatin and its metabolites
    • Backman JT, Luurila H, Neuvonen M, Neuvonen PJ. Rifampin markedly decreases and gemfibrozil increases the plasma concentrations of atorvastatin and its metabolites. Clin Pharmacol Ther 2005;78:154-67
    • (2005) Clin Pharmacol Ther , vol.78 , pp. 154-167
    • Backman, J.T.1    Luurila, H.2    Neuvonen, M.3    Neuvonen, P.J.4
  • 134
    • 0035023185 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of fluvastatin
    • Scripture CD, Pieper JA. Clinical pharmacokinetics of fluvastatin. Clin Pharmacokinet 2001;40:263-81
    • (2001) Clin Pharmacokinet , vol.40 , pp. 263-281
    • Scripture, C.D.1    Pieper, J.A.2
  • 135
    • 84886799677 scopus 로고    scopus 로고
    • Effect of a single-dose rifampin on the pharmacokinetics of pitavastatin in healthy volunteers
    • published online 7 July 2013 doi: 10.1007/s00228-013-1554-0
    • Chen Y, Zhang W, Huang WH, et al. Effect of a single-dose rifampin on the pharmacokinetics of pitavastatin in healthy volunteers. Eur J Clin Pharmacol 2013;published online 7 July 2013; doi: 10.1007/s00228-013-1554-0
    • (2013) Eur J Clin Pharmacol
    • Chen, Y.1    Zhang, W.2    Huang, W.H.3
  • 136
    • 48549091752 scopus 로고    scopus 로고
    • Pharmacokinetics of rosuvastatin when coadministered with rifampicin in healthy males: A randomized, single-blind, placebo-controlled, crossover study
    • Zhang W, Deng S, Chen XP, et al. Pharmacokinetics of rosuvastatin when coadministered with rifampicin in healthy males: A randomized, single-blind, placebo-controlled, crossover study. Clin Ther 2008;30:1283-9
    • (2008) Clin Ther , vol.30 , pp. 1283-1289
    • Zhang, W.1    Deng, S.2    Chen, X.P.3
  • 137
    • 1142274350 scopus 로고    scopus 로고
    • Oral anticoagulant drug interactions with statins: Case report of fluvastatin and review of the literature
    • Andrus MR. Oral anticoagulant drug interactions with statins: Case report of fluvastatin and review of the literature. Pharmacotherapy 2004;24:285-90
    • (2004) Pharmacotherapy , vol.24 , pp. 285-290
    • Andrus, M.R.1
  • 138
    • 84856429823 scopus 로고    scopus 로고
    • Effect of pitavastatin vs. Rosuvastatin on international normalized ratio in healthy volunteers on steady-state warfarin
    • Yu CY, Campbell SE, Zhu B, et al. Effect of pitavastatin vs. rosuvastatin on international normalized ratio in healthy volunteers on steady-state warfarin. Curr Med Res Opin 2012;28:187-94
    • (2012) Curr Med Res Opin , vol.28 , pp. 187-194
    • Yu, C.Y.1    Campbell, S.E.2    Zhu, B.3
  • 139
    • 84861112762 scopus 로고    scopus 로고
    • A clinically significant interaction between warfarin and simvastatin is unique to carriers of the CYP2C9.3 allele
    • Andersson ML, Eliasson E, Lindh JD. A clinically significant interaction between warfarin and simvastatin is unique to carriers of the CYP2C9.*3 allele. Pharmacogenomics 2012;13:757-62
    • (2012) Pharmacogenomics , vol.13 , pp. 757-762
    • Andersson, M.L.1    Eliasson, E.2    Lindh, J.D.3
  • 140
    • 80051625423 scopus 로고    scopus 로고
    • Drug-drug interaction study to assess the effects of multiple-dose pitavastatin on steady-state warfarin in healthy adult volunteers
    • Inagaki Y, Hunt T, Arana B, et al. Drug-drug interaction study to assess the effects of multiple-dose pitavastatin on steady-state warfarin in healthy adult volunteers. J Clin Pharmacol 2011;51:1302-9
    • (2011) J Clin Pharmacol , vol.51 , pp. 1302-1309
    • Inagaki, Y.1    Hunt, T.2    Arana, B.3
  • 141
    • 84856237147 scopus 로고    scopus 로고
    • The effect of herbal medicine danshensu and ursolic acid on pharmacokinetics of rosuvastatin in rats
    • Wen JH, Xiong YQ. The effect of herbal medicine danshensu and ursolic acid on pharmacokinetics of rosuvastatin in rats. Eur J Drug Metab Pharmacokinet 2011;36:205-11
    • (2011) Eur J Drug Metab Pharmacokinet , vol.36 , pp. 205-211
    • Wen, J.H.1    Xiong, Y.Q.2
  • 142
    • 84885624400 scopus 로고    scopus 로고
    • Effects of piperine cinnamic acid and gallic acid on rosuvastatin pharmacokinetics in rats
    • published Online 3 December 2012 doi: 10.1002/ptr.4894
    • Basu S, Jana S, Patel VB, Patel H. Effects of piperine, cinnamic acid and gallic acid on rosuvastatin pharmacokinetics in rats. Phytother Res 2012;published online 3 December 2012; doi: 10.1002/ptr.4894
    • (2012) Phytother Res
    • Basu, S.1    Jana, S.2    Patel, V.B.3    Patel, H.4
  • 143
    • 39449122141 scopus 로고    scopus 로고
    • The effect of herbal medicine baicalin on pharmacokinetics of rosuvastatin, substrate of organic anion-Transporting polypeptide 1B1
    • Fan L, Zhang W, Guo D, et al. The effect of herbal medicine baicalin on pharmacokinetics of rosuvastatin, substrate of organic anion-Transporting polypeptide 1B1. Clin Pharmacol Ther 2008;83:471-6
    • (2008) Clin Pharmacol Ther , vol.83 , pp. 471-476
    • Fan, L.1    Zhang, W.2    Guo, D.3
  • 144
    • 47949132189 scopus 로고    scopus 로고
    • Hepatic nuclear factor 1alpha inhibitor ursodeoxycholic acid influences pharmacokinetics of the organic anion transporting polypeptide 1B1 substrate rosuvastatin and bilirubin
    • He YJ, Zhang W, Tu JH, et al. Hepatic nuclear factor 1alpha inhibitor ursodeoxycholic acid influences pharmacokinetics of the organic anion transporting polypeptide 1B1 substrate rosuvastatin and bilirubin. Drug Metab Dispos 2008;36:1453-6
    • (2008) Drug Metab Dispos , vol.36 , pp. 1453-1456
    • He, Y.J.1    Zhang, W.2    Tu, J.H.3
  • 145
    • 33745243715 scopus 로고    scopus 로고
    • Drug-drug interaction between pitavastatin and various drugs via OATP1B1
    • Hirano M, Maeda K, Shitara Y, Sugiyama Y. Drug-drug interaction between pitavastatin and various drugs via OATP1B1. Drug Metab Dispos 2006;34:1229-36
    • (2006) Drug Metab Dispos , vol.34 , pp. 1229-1236
    • Hirano, M.1    Maeda, K.2    Shitara, Y.3    Sugiyama, Y.4
  • 146
    • 33745231761 scopus 로고    scopus 로고
    • Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans
    • Yamashiro W, Maeda K, Hirouchi M, et al. Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans. Drug Metab Dispos 2006;34:1247-54
    • (2006) Drug Metab Dispos , vol.34 , pp. 1247-1254
    • Yamashiro, W.1    Maeda, K.2    Hirouchi, M.3
  • 147
    • 84859575440 scopus 로고    scopus 로고
    • Pharmacokinetic interaction between pitavastatin and valsartan: A randomized, open-labeled crossover study in healthy male Korean volunteers
    • Jung JA, Noh YH, Jin S, et al. Pharmacokinetic interaction between pitavastatin and valsartan: A randomized, open-labeled crossover study in healthy male Korean volunteers. Clin Ther 2012;34:958-65
    • (2012) Clin Ther , vol.34 , pp. 958-965
    • Jung, J.A.1    Noh, Y.H.2    Jin, S.3
  • 148
    • 50949134552 scopus 로고    scopus 로고
    • Rosuvastatin: Efficacy, safety and clinical effectiveness
    • Soran H, Durrington P. Rosuvastatin: Efficacy, safety and clinical effectiveness. Expert Opin Pharmacother 2008;9:2145-60
    • (2008) Expert Opin Pharmacother , vol.9 , pp. 2145-2160
    • Soran, H.1    Durrington, P.2
  • 149
    • 25444500664 scopus 로고    scopus 로고
    • Rosuvastatin: A risk-benefit assessment for intensive lipid lowering
    • Ferdinand KC. Rosuvastatin: A risk-benefit assessment for intensive lipid lowering. Expert Opin Pharmacother 2005;6:1897-910
    • (2005) Expert Opin Pharmacother , vol.6 , pp. 1897-1910
    • Ferdinand, K.C.1
  • 150
    • 84858843129 scopus 로고    scopus 로고
    • The clinical impact of pitavastatin: Comparative studies with other statins on ldl-c and hdl-c
    • Teramoto T. The clinical impact of pitavastatin: Comparative studies with other statins on LDL-C and HDL-C. Expert Opin Pharmacother 2012;13:859-65
    • (2012) Expert Opin Pharmacother , vol.13 , pp. 859-865
    • Teramoto, T.1
  • 151
    • 80052787432 scopus 로고    scopus 로고
    • Place of pitavastatin in the statin armamentarium: Promising evidence for a role in diabetes mellitus
    • Kawai Y, Sato-Ishida R, Motoyama A, Kajinami K. Place of pitavastatin in the statin armamentarium: Promising evidence for a role in diabetes mellitus. Drug Des Devel Ther 2011;5:283-97
    • (2011) Drug Des Devel Ther , vol.5 , pp. 283-297
    • Kawai, Y.1    Sato-Ishida, R.2    Motoyama, A.3    Kajinami, K.4
  • 152
    • 76949094840 scopus 로고    scopus 로고
    • Risk factors and drug interactions predisposing to statin-induced myopathy: Implications for risk assessment, prevention and treatment
    • Chatzizisis YS, Koskinas KC, Misirli G, et al. Risk factors and drug interactions predisposing to statin-induced myopathy: Implications for risk assessment, prevention and treatment. Drug Saf 2010;33:171-87
    • (2010) Drug Saf , vol.33 , pp. 171-187
    • Chatzizisis, Y.S.1    Koskinas, K.C.2    Misirli, G.3
  • 153
    • 33845876333 scopus 로고    scopus 로고
    • Risks associated with statin therapy: A systematic overview of randomized clinical trials
    • Kashani A, Phillips CO, Foody JM, et al. Risks associated with statin therapy: A systematic overview of randomized clinical trials. Circulation 2006;114:2788-97
    • (2006) Circulation , vol.114 , pp. 2788-2797
    • Kashani, A.1    Phillips, C.O.2    Foody, J.M.3
  • 154
    • 84857127538 scopus 로고    scopus 로고
    • Statin-induced myotoxicity: Pharmacokinetic differences among statins and the risk of rhabdomyolysis, with particular reference to pitavastatin
    • Catapano AL. Statin-induced myotoxicity: Pharmacokinetic differences among statins and the risk of rhabdomyolysis, with particular reference to pitavastatin. Curr Vasc Pharmacol 2012;10:257-67
    • (2012) Curr Vasc Pharmacol , vol.10 , pp. 257-267
    • Catapano, A.L.1
  • 155
    • 70249096009 scopus 로고    scopus 로고
    • Pharmacogenetics of hmg-coa reductase inhibitors: Optimizing the prevention of coronary heart disease
    • Hu M, Mak VWL, Chu TTY, et al. Pharmacogenetics of HMG-CoA reductase inhibitors: Optimizing the prevention of coronary heart disease. Curr Pharmacogenomics Personalized Med 2009;7:1-26
    • (2009) Curr Pharmacogenomics Personalized Med , vol.7 , pp. 1-26
    • Hu, M.1    Mak, V.W.L.2    Chu, T.T.Y.3
  • 156
    • 59049096478 scopus 로고    scopus 로고
    • Ins and outs of the abcg2 multidrug transporter: An update on in vitro functional assays
    • Hegedus C, Szakacs G, Homolya L, et al. Ins and outs of the ABCG2 multidrug transporter: An update on in vitro functional assays. Adv Drug Deliv Rev 2009;61:47-56
    • (2009) Adv Drug Deliv Rev , vol.61 , pp. 47-56
    • Hegedus, C.1    Szakacs, G.2    Homolya, L.3
  • 157
    • 69049098314 scopus 로고    scopus 로고
    • Impact of cholesterol on abc and slc transporters expression and function and its role in disposition variability to lipid-lowering drugs
    • Rodrigues AC, Hirata MH, Hirata RD. Impact of cholesterol on ABC and SLC transporters expression and function and its role in disposition variability to lipid-lowering drugs. Pharmacogenomics 2009;10:1007-16
    • (2009) Pharmacogenomics , vol.10 , pp. 1007-1016
    • Rodrigues, A.C.1    Hirata, M.H.2    Hirata, R.D.3


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