메뉴 건너뛰기




Volumn 57, Issue 2, 2004, Pages 181-187

Effect of rifampicin on pravastatin pharmacokinetics in healthy subjects

Author keywords

Interaction; Pravastatin; Rifampicin

Indexed keywords

PLACEBO; PRAVASTATIN; RIFAMPICIN; RIFARM;

EID: 1242284362     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.2003.01972.x     Document Type: Article
Times cited : (66)

References (32)
  • 2
    • 0026464616 scopus 로고
    • Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
    • Kolars JC, Schmiedlin-Ren P, Schuetz JD, Fang C, Watkins PB. Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes. J Clin Invest 1992; 90: 1871-8.
    • (1992) J Clin Invest , vol.90 , pp. 1871-1878
    • Kolars, J.C.1    Schmiedlin-Ren, P.2    Schuetz, J.D.3    Fang, C.4    Watkins, P.B.5
  • 3
    • 0024603850 scopus 로고
    • Metabolism of cyclosporin A. IV. Purification and identification of the rifampicin-inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P450IIIA gene subfamily
    • Combalbert J, Fabre I, Fabre G et al. Metabolism of cyclosporin A. IV. Purification and identification of the rifampicin-inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P450IIIA gene subfamily. Drug Metab Dispos 1989; 17: 197-207.
    • (1989) Drug Metab Dispos , vol.17 , pp. 197-207
    • Combalbert, J.1    Fabre, I.2    Fabre, G.3
  • 4
    • 0032754284 scopus 로고    scopus 로고
    • The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin
    • Greiner B, Eichelbaum M, Fritz P et al. The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin. J Clin Invest 1999; 104: 147-53.
    • (1999) J Clin Invest , vol.104 , pp. 147-153
    • Greiner, B.1    Eichelbaum, M.2    Fritz, P.3
  • 5
    • 0033724658 scopus 로고    scopus 로고
    • The effect of rifampin treatment on intestinal expression of human MRP transporters
    • Fromm MF, Kauffmann HM, Fritz P et al. The effect of rifampin treatment on intestinal expression of human MRP transporters. Am J Pathol 2000; 157: 1575-80.
    • (2000) Am J Pathol , vol.157 , pp. 1575-1580
    • Fromm, M.F.1    Kauffmann, H.M.2    Fritz, P.3
  • 6
    • 0032498303 scopus 로고    scopus 로고
    • An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway
    • Kliewer SA, Moore JT, Wade L et al. An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway. Cell 1998; 92: 73-82.
    • (1998) Cell , vol.92 , pp. 73-82
    • Kliewer, S.A.1    Moore, J.T.2    Wade, L.3
  • 7
    • 0032169485 scopus 로고    scopus 로고
    • The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions
    • Lehmann JM, McKee DD, Watson MA, Willson TM, Moore JT, Kliewer SA. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. J Clin Invest 1998; 102: 1016-23.
    • (1998) J Clin Invest , vol.102 , pp. 1016-1023
    • Lehmann, J.M.1    McKee, D.D.2    Watson, M.A.3    Willson, T.M.4    Moore, J.T.5    Kliewer, S.A.6
  • 8
    • 0037216648 scopus 로고    scopus 로고
    • Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation
    • Tirona RC, Leake BF, Wolkoff AW, Kim RB. Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation. J Pharmacol Exp Ther 2003; 304: 223-8.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 223-228
    • Tirona, R.C.1    Leake, B.F.2    Wolkoff, A.W.3    Kim, R.B.4
  • 10
    • 0032825735 scopus 로고    scopus 로고
    • Small intestinal metabolism of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor lovastatin and comparison with pravastatin
    • Jacobsen W, Kirchner G, Hallensleben K et al. Small intestinal metabolism of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor lovastatin and comparison with pravastatin. J Pharmacol Exp Ther 1999; 291: 131-9.
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 131-139
    • Jacobsen, W.1    Kirchner, G.2    Hallensleben, K.3
  • 11
    • 0032911163 scopus 로고    scopus 로고
    • Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver
    • Jacobsen W, Kirchner G, Hallensleben K et al. Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3- methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver. Drug Metab Dispos 1999; 27: 173-9.
    • (1999) Drug Metab Dispos , vol.27 , pp. 173-179
    • Jacobsen, W.1    Kirchner, G.2    Hallensleben, K.3
  • 13
    • 0030862073 scopus 로고    scopus 로고
    • Biliary excretion of pravastatin in rats: Contribution of the excretion pathway mediated by canalicular multispecific organic anion transporter
    • Yamazaki M, Akiyama S, Ni'inuma K, Nishigaki R, Sugiyama Y. Biliary excretion of pravastatin in rats: contribution of the excretion pathway mediated by canalicular multispecific organic anion transporter. Drug Metab Dispos 1997; 25: 1123-9.
    • (1997) Drug Metab Dispos , vol.25 , pp. 1123-1129
    • Yamazaki, M.1    Akiyama, S.2    Ni'Inuma, K.3    Nishigaki, R.4    Sugiyama, Y.5
  • 14
    • 0033601257 scopus 로고    scopus 로고
    • A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters
    • Hsiang B, Zhu Y, Wang Z et al. A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters. J Biol Chem 1999; 274: 37161-8.
    • (1999) J Biol Chem , vol.274 , pp. 37161-37168
    • Hsiang, B.1    Zhu, Y.2    Wang, Z.3
  • 15
    • 0037131885 scopus 로고    scopus 로고
    • Pharmacogenomics of organic anion-transporting polypeptides (OATP)
    • Tirona RG, Kim RB. Pharmacogenomics of organic anion-transporting polypeptides (OATP). Adv Drug Deliv Rev 2002; 54: 1343-52.
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 1343-1352
    • Tirona, R.G.1    Kim, R.B.2
  • 16
    • 0031892901 scopus 로고    scopus 로고
    • Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole
    • Neuvonen PJ, Kantola T, Kivistö KT. Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole. Clin Pharmacol Ther 1998; 63: 332-41.
    • (1998) Clin Pharmacol Ther , vol.63 , pp. 332-341
    • Neuvonen, P.J.1    Kantola, T.2    Kivistö, K.T.3
  • 17
    • 0037040378 scopus 로고    scopus 로고
    • Pharmacokinetic interactions between protease inhibitors and statins in HIV seronegative volunteers
    • Fichtenbaum CJ, Gerber JG, Rosenkranz SL et al. Pharmacokinetic interactions between protease inhibitors and statins in HIV seronegative volunteers. ACTG Study A5047 AIDS 2002; 16: 569-77.
    • (2002) ACTG Study A5047 AIDS , vol.16 , pp. 569-577
    • Fichtenbaum, C.J.1    Gerber, J.G.2    Rosenkranz, S.L.3
  • 18
    • 0033834358 scopus 로고    scopus 로고
    • Quantitative determination of pravastatin and its biotransformation products in human serum by turbo ion spray LC/MS/MS
    • Mulvana D, Jemal M, Pulver SC. Quantitative determination of pravastatin and its biotransformation products in human serum by turbo ion spray LC/MS/MS. J Pharm Biomed Anal 2000; 23: 851-66.
    • (2000) J Pharm Biomed Anal , vol.23 , pp. 851-866
    • Mulvana, D.1    Jemal, M.2    Pulver, S.C.3
  • 20
    • 0023898749 scopus 로고
    • Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells
    • Zamora JM, Pearce HL, Beck WT. Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells. Mol Pharmacol 1988; 33: 454-62.
    • (1988) Mol Pharmacol , vol.33 , pp. 454-462
    • Zamora, J.M.1    Pearce, H.L.2    Beck, W.T.3
  • 21
    • 0028879438 scopus 로고
    • Structure-activity-relationship studies on modulators of the multidrug transporter P-glycoprotein - An overview
    • Ecker G, Chiba P. Structure-activity-relationship studies on modulators of the multidrug transporter P-glycoprotein - an overview. Wien Klin Wochenschr 1995; 107: 681-6.
    • (1995) Wien Klin Wochenschr , vol.107 , pp. 681-686
    • Ecker, G.1    Chiba, P.2
  • 22
    • 0035985610 scopus 로고    scopus 로고
    • Expression of multidrug resistance-associated protein 2 (MRP2) in normal human tissues and carcinomas using tissue microarrays
    • Sandusky GE, Mintze KS, Pratt SE, Dantzig AH. Expression of multidrug resistance-associated protein 2 (MRP2) in normal human tissues and carcinomas using tissue microarrays. Histopathology 2002; 41: 65-74.
    • (2002) Histopathology , vol.41 , pp. 65-74
    • Sandusky, G.E.1    Mintze, K.S.2    Pratt, S.E.3    Dantzig, A.H.4
  • 23
    • 0036293982 scopus 로고    scopus 로고
    • Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver
    • Vavricka SR, Van Montfoort J, Ha HR, Meier PJ, Fattinger K. Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver. Hepatology 2002; 36: 164-72.
    • (2002) Hepatology , vol.36 , pp. 164-172
    • Vavricka, S.R.1    Van Montfoort, J.2    Ha, H.R.3    Meier, P.J.4    Fattinger, K.5
  • 24
    • 0027264759 scopus 로고
    • The effects of inducing agents on cytochrome P450 and UDP-glucuronyltransferase activities in human HEPG2 hepatoma cells
    • Doostdar H, Grant MH, Melvin WT, Wolf CR, Burke MD. The effects of inducing agents on cytochrome P450 and UDP-glucuronyltransferase activities in human HEPG2 hepatoma cells. Biochem Pharmacol 1993; 46: 629-35.
    • (1993) Biochem Pharmacol , vol.46 , pp. 629-635
    • Doostdar, H.1    Grant, M.H.2    Melvin, W.T.3    Wolf, C.R.4    Burke, M.D.5
  • 26
    • 0034035056 scopus 로고    scopus 로고
    • Enzyme induction in the elderly. Effect of rifampin on the pharmacokinetics and pharmacodynamics of propafenone
    • Dilger K, Hofmann U, Klotz U. Enzyme induction in the elderly. effect of rifampin on the pharmacokinetics and pharmacodynamics of propafenone. Clin Pharmacol Ther 2000; 67: 512-20.
    • (2000) Clin Pharmacol Ther , vol.67 , pp. 512-520
    • Dilger, K.1    Hofmann, U.2    Klotz, U.3
  • 27
    • 0035652201 scopus 로고    scopus 로고
    • Different effects of St John's wort on the pharmacokinetics of simvastatin and pravastatin
    • Sugimoto K, Ohmori M, Tsuruoka S et al. Different effects of St John's wort on the pharmacokinetics of simvastatin and pravastatin. Clin Pharmacol Ther 2001; 70: 518-24.
    • (2001) Clin Pharmacol Ther , vol.70 , pp. 518-524
    • Sugimoto, K.1    Ohmori, M.2    Tsuruoka, S.3
  • 28
    • 0032937343 scopus 로고    scopus 로고
    • The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin: Effect on human cytochrome P-450 and implications for metabolic drug interactions
    • Fischer V, Johanson L, Heitz F et al. The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin: effect on human cytochrome P-450 and implications for metabolic drug interactions. Drug Metab Dispos 1999; 27: 410-16.
    • (1999) Drug Metab Dispos , vol.27 , pp. 410-416
    • Fischer, V.1    Johanson, L.2    Heitz, F.3
  • 29
    • 0028275679 scopus 로고
    • Updated clinical safety experience with fluvastatin
    • Jokubaitis LA. Updated clinical safety experience with fluvastatin. Am J Cardiol 1994; 73: 18D-24D.
    • (1994) Am J Cardiol , vol.73
    • Jokubaitis, L.A.1
  • 31
    • 0029758869 scopus 로고    scopus 로고
    • Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid
    • Neuvonen PJ, Jalava KM. Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid. Clin Pharmacol Ther 1996; 60: 54-61.
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 54-61
    • Neuvonen, P.J.1    Jalava, K.M.2
  • 32
    • 0025316348 scopus 로고
    • In vitro and in vivo biotransformation of simvastatin, an inhibitor of HMG CoA reductase
    • Vickers S, Duncan CA, Vyas KP et al. In vitro and in vivo biotransformation of simvastatin, an inhibitor of HMG CoA reductase. Drug Metab Dispos 1990; 18: 476-83.
    • (1990) Drug Metab Dispos , vol.18 , pp. 476-483
    • Vickers, S.1    Duncan, C.A.2    Vyas, K.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.