Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: Similarities and difference in the metabolism of pitavastatin in monkeys and humans

Xenobiotica

Volumn 33, Issue 7, 2003, Pages 789-803

  Yamada, I ^a   Fujino, H ^a   Shimada, S ^a   Kojima, J ^a  

^a KOWA COMPANY LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITROPHENOL; 5 HYDROXYPENTANOIC ACID DERIVATIVE; DRUG METABOLITE; FIBRIC ACID DERIVATIVE; GLUCURONIC ACID; GLUCURONOSYLTRANSFERASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; KETOPROFEN; LACTONE; NICOTINIC ACID; PITAVASTATIN; PRAVASTATIN; PROBUCOL; STATINE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE; VALERIC ACID DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DOG; DRUG CLEARANCE; DRUG OXIDATION; DRUG STRUCTURE; HUMAN; HYPERLIPIDEMIA; IN VITRO STUDY; KIDNEY MICROSOME; LIVER MICROSOME; MONKEY; NONHUMAN; RABBIT; RAT; SPECIES DIFFERENCE; STRUCTURE ANALYSIS;

ANIMALS; DOGS; ENZYME INHIBITORS; HAPLORHINI; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; KIDNEY; LACTONES; LIVER; METABOLIC CLEARANCE RATE; MICROSOMES; QUINOLINES; RABBITS; RATS; SPECIES SPECIFICITY; URIDINE DIPHOSPHATE GLUCURONIC ACID;

ANIMALIA; CANIS FAMILIARIS; ORYCTOLAGUS CUNICULUS;

EID: 0042531819     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/0049825031000121635     Document Type: Article

References (22)

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