Transporter-mediated influx and efflux mechanisms of pitavastatin, a new inhibitor of HMG-CoA reductase

Journal of Pharmacy and Pharmacology

Volumn 57, Issue 10, 2005, Pages 1305-1311

  Fujino, Hideki ^a   Saito, Tsuyoshi ^a   Ogawa, Shin Ichiro ^a   Kojima, Junji ^a  

^a KOWA COMPANY LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ACID; ADENOSINE TRIPHOSPHATASE; BREAST CANCER RESISTANCE PROTEIN; CARRIER PROTEIN; GLYCOPROTEIN P; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LACTONE; NEW DRUG; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTER 2; ORGANIC ANION TRANSPORTER 3; ORGANIC ANION TRANSPORTER 4; ORGANIC ANION TRANSPORTER 8; PITAVASTATIN; PITAVASTATIN LACTONE; SODIUM TAUROCHOLIC ACID COTRANSPORT PROTEIN; SOLUTE CARRIER TRANSPORTER; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG TRANSPORT; DRUG UPTAKE; HUMAN; MEMBRANE VESICLE; MICHAELIS CONSTANT; NONHUMAN; OOCYTE; PROTEIN EXPRESSION; PROTEIN HYDROLYSIS; RAT; XENOPUS LAEVIS;

ADENOSINE TRIPHOSPHATASES; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CARBON RADIOISOTOPES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; KINETICS; NEOPLASM PROTEINS; OOCYTES; ORGANIC ANION TRANSPORT POLYPEPTIDE C; ORGANIC ANION TRANSPORTERS; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; QUINOLINES; RATS; SYMPORTERS; XENOPUS LAEVIS;

EID: 27544515516     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.57.10.0009     Document Type: Article

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