Development of a fluorescence-based assay for screening of modulators of human Organic Anion Transporter 1B3 (OATP1B3)

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 62, Issue 1, 2006, Pages 39-43

  Baldes, C ^a   Koenig, P ^a   Neumann, D ^a   Lenhof, H P ^a   Kohlbacher, O ^b   Lehr, C M ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Active transport; Bioavailability; Hepatic uptake; Human; OATP; Substrate specifity

Indexed keywords

BROMSULFOPHTHALEIN; DIGOXIN; ESTRADIOL 17 GLUCURONIDE; FLUO 3; GLYCOCHOLIC ACID; KETOCONAZOLE; METHOTREXATE; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTER 1B3; OUABAIN; PRASTERONE SULFATE; RIFAMPICIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL STRAIN; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG TRANSPORT; EMBRYO; FLUORESCENCE ANALYSIS; HUMAN; HUMAN CELL; PROTEIN EXPRESSION;

ANILINE COMPOUNDS; CELL LINE; DRUG EVALUATION, PRECLINICAL; FLUORESCENT DYES; HUMANS; INHIBITORY CONCENTRATION 50; KETOCONAZOLE; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; OUABAIN; RIFAMPIN; TRANSFECTION; XANTHENES;

EID: 28444481386     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2005.06.001     Document Type: Article

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