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Volumn 83, Issue 3, 2008, Pages 471-476

The effect of herbal medicine baicalin on pharmacokinetics of rosuvastatin, substrate of organic anion-transporting polypeptide 1B1

Author keywords

[No Author keywords available]

Indexed keywords

BAICALIN; CYTOCHROME P450 2C9; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTING POLYPEPTIDE 1B1; PLACEBO; ROSUVASTATIN; UNCLASSIFIED DRUG;

EID: 39449122141     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/sj.clpt.6100318     Document Type: Article
Times cited : (73)

References (44)
  • 1
    • 21644454094 scopus 로고    scopus 로고
    • Metabolic activities of ginsenoside Rb1, baicalin, glycyrrhizin and geniposide to their bioactive compounds by human intestinal microflora
    • Yim, J.S. et al. Metabolic activities of ginsenoside Rb1, baicalin, glycyrrhizin and geniposide to their bioactive compounds by human intestinal microflora. Biol. Pharm. Bull. 27, 1580-1583 (2004).
    • (2004) Biol. Pharm. Bull , vol.27 , pp. 1580-1583
    • Yim, J.S.1
  • 2
    • 0036583671 scopus 로고    scopus 로고
    • Metabolism of constituents in Huangqin-Tang, a prescription in traditional Chinese medicine, by human intestinal flora
    • Zuo, F. et al. Metabolism of constituents in Huangqin-Tang, a prescription in traditional Chinese medicine, by human intestinal flora. Biol. Pharm. Bull. 25, 558-563 (2002).
    • (2002) Biol. Pharm. Bull , vol.25 , pp. 558-563
    • Zuo, F.1
  • 3
    • 0025217479 scopus 로고
    • Biliary excretion of metabolites of baicalin and baicalin in rats
    • Abe, K., Inoue, O. & Yumioka, E. Biliary excretion of metabolites of baicalin and baicalin in rats. Biol. Pharm. Bull. 38, 209-211 (1990).
    • (1990) Biol. Pharm. Bull , vol.38 , pp. 209-211
    • Abe, K.1    Inoue, O.2    Yumioka, E.3
  • 4
    • 0034534704 scopus 로고    scopus 로고
    • Baicalin, the predominant flavone glucuronide of scutellariae radix, is absorbed from the rat gastrointestinal tract as the aglycone and restored to its original form
    • Akao, T., Kawabata, K. & Yanagisawa, E. Baicalin, the predominant flavone glucuronide of scutellariae radix, is absorbed from the rat gastrointestinal tract as the aglycone and restored to its original form. J. Pharm. Pharmacol. 52, 1563-1568 (2000).
    • (2000) J. Pharm. Pharmacol , vol.52 , pp. 1563-1568
    • Akao, T.1    Kawabata, K.2    Yanagisawa, E.3
  • 5
    • 33847790184 scopus 로고    scopus 로고
    • Comparative pharmacokinetics of baicalin after oral administration of pure baicalin, Radix scutellariae extract and Huang-Lian-Jie-Du-Tang to rats
    • Lu, T. et al. Comparative pharmacokinetics of baicalin after oral administration of pure baicalin, Radix scutellariae extract and Huang-Lian-Jie-Du-Tang to rats. J. Ethnopharmacol. 110, 12-18 (2007).
    • (2007) J. Ethnopharmacol , vol.110 , pp. 12-18
    • Lu, T.1
  • 6
    • 0036963678 scopus 로고    scopus 로고
    • Rosuvastatin: A highly effective new HMG-CoA reductase inhibitor
    • Olsson, A.G., McTaggart, F. & Raza, A. Rosuvastatin: a highly effective new HMG-CoA reductase inhibitor. Cardiovasc. Drug Rev. 20, 303-308 (2002).
    • (2002) Cardiovasc. Drug Rev , vol.20 , pp. 303-308
    • Olsson, A.G.1    McTaggart, F.2    Raza, A.3
  • 7
    • 0036915307 scopus 로고    scopus 로고
    • Effects of rosuvastatin and atorvastatin compared over 52 weeks of treatment in patients with hypercholesterolemia
    • Olsson, A.G. et al. Effects of rosuvastatin and atorvastatin compared over 52 weeks of treatment in patients with hypercholesterolemia. Am. Heart J. 144, 1044-1051 (2002).
    • (2002) Am. Heart J , vol.144 , pp. 1044-1051
    • Olsson, A.G.1
  • 8
    • 0036910821 scopus 로고    scopus 로고
    • Efficacy and safety of rosuvastatin compared with pravastatin and simvastatin in patients with hypercholesterolemia: A randomized, double-blind, 52-week trial
    • Brown, W.V. et al. Efficacy and safety of rosuvastatin compared with pravastatin and simvastatin in patients with hypercholesterolemia: a randomized, double-blind, 52-week trial. Am. Heart J. 144, 1036-1043 (2002).
    • (2002) Am. Heart J , vol.144 , pp. 1036-1043
    • Brown, W.V.1
  • 9
    • 0036840329 scopus 로고    scopus 로고
    • Liver-specific distribution of rosuvastatin in rats: Comparison with pravastatin and simvastatin
    • Nezasa, K. et al. Liver-specific distribution of rosuvastatin in rats: comparison with pravastatin and simvastatin. Drug Metab. Dispos. 30, 1158 (2002).
    • (2002) Drug Metab. Dispos , vol.30 , pp. 1158
    • Nezasa, K.1
  • 11
    • 0002186061 scopus 로고    scopus 로고
    • Rosuvastatin is a high affinity substrate of hepatic organic anion transporter OATP1B1
    • Brown, C.D.A., Windass, A., Bleasby, K. & Lauffart, B. Rosuvastatin is a high affinity substrate of hepatic organic anion transporter OATP1B1. Atherosclerosis 2, 90 (2001).
    • (2001) Atherosclerosis , vol.2 , pp. 90
    • Brown, C.D.A.1    Windass, A.2    Bleasby, K.3    Lauffart, B.4
  • 12
    • 3542992126 scopus 로고    scopus 로고
    • Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine
    • Simonson, S.G. et al. Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine. Clin. Pharmacol. Ther. 76, 167-177 (2004).
    • (2004) Clin. Pharmacol. Ther , vol.76 , pp. 167-177
    • Simonson, S.G.1
  • 13
    • 0033601257 scopus 로고    scopus 로고
    • A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters
    • Hsiang, B. et al. A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters. J. Biol. Chem. 274, 37161-37168 (1999).
    • (1999) J. Biol. Chem , vol.274 , pp. 37161-37168
    • Hsiang, B.1
  • 14
    • 0035012075 scopus 로고    scopus 로고
    • Human liver-specific organic anion transporter, LST-1, mediates uptake of pravastatin by human hepatocytes
    • Nakai, D. et al. Human liver-specific organic anion transporter, LST-1, mediates uptake of pravastatin by human hepatocytes. J. Pharmacol. Exp. Ther. 297, 861-867 (2001).
    • (2001) J. Pharmacol. Exp. Ther , vol.297 , pp. 861-867
    • Nakai, D.1
  • 15
    • 0037310871 scopus 로고    scopus 로고
    • Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporine A
    • Shitara, Y., Itoh, T., Sato, H., Li, A.P. & Sugiyama, Y. Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporine A. J. Pharmacol. Exp. Ther. 304, 610-616 (2003).
    • (2003) J. Pharmacol. Exp. Ther , vol.304 , pp. 610-616
    • Shitara, Y.1    Itoh, T.2    Sato, H.3    Li, A.P.4    Sugiyama, Y.5
  • 16
    • 0038209381 scopus 로고    scopus 로고
    • Polymorphisms of OATP1B1 (SLC21A6) and OAT3 (SLC22A8) genes: Consequences for pravastatin pharmacokinetics
    • Nishizato, Y. et al. Polymorphisms of OATP1B1 (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics. Clin. Pharmacol. Ther. 73, 554-565 (2003).
    • (2003) Clin. Pharmacol. Ther , vol.73 , pp. 554-565
    • Nishizato, Y.1
  • 17
    • 2042469487 scopus 로고    scopus 로고
    • Evidence for inverse effects of OATP1B1 (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics
    • Mwinyi, J., Johne, A., Bauer, S., Roots, I. & Gerloff, T. Evidence for inverse effects of OATP1B1 (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics. Clin. Pharmacol. Ther. 75, 415-421 (2004).
    • (2004) Clin. Pharmacol. Ther , vol.75 , pp. 415-421
    • Mwinyi, J.1    Johne, A.2    Bauer, S.3    Roots, I.4    Gerloff, T.5
  • 18
    • 3242808852 scopus 로고    scopus 로고
    • High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C OATP1B1)
    • Niemi, M. et al. High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C OATP1B1). Pharmacogenetics 14, 429-440 (2004).
    • (2004) Pharmacogenetics , vol.14 , pp. 429-440
    • Niemi, M.1
  • 19
    • 11144354934 scopus 로고    scopus 로고
    • The effect of gemfibrozil on the pharmacokinetics of rosuvastatin
    • Schneck, D.W. et al. The effect of gemfibrozil on the pharmacokinetics of rosuvastatin. Clin. Pharmacol. Ther. 75, 455-463 (2004).
    • (2004) Clin. Pharmacol. Ther , vol.75 , pp. 455-463
    • Schneck, D.W.1
  • 20
    • 33646536542 scopus 로고    scopus 로고
    • Drug and bile acid transporters in rosuvastatin hepatic uptake: Function, expression, and pharmacogenetics
    • Ho, R.H. et al. Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics. Gastroenterology 130, 1793-1806 (2006).
    • (2006) Gastroenterology , vol.130 , pp. 1793-1806
    • Ho, R.H.1
  • 22
    • 0344664550 scopus 로고    scopus 로고
    • Metabolism, excretion and pharmacokinetics of rosuvastatin
    • Martin, P.D. et al. Metabolism, excretion and pharmacokinetics of rosuvastatin. Clin. Ther. 25, 2822-2835 (2003).
    • (2003) Clin. Ther , vol.25 , pp. 2822-2835
    • Martin, P.D.1
  • 23
    • 0000626919 scopus 로고    scopus 로고
    • ZD4522 - an HMG-CoA reductase inhibitor free of metabolically mediated drug interactions: Metabolic studies in human in vitro systems
    • McCormick, A.D. et al. ZD4522 - an HMG-CoA reductase inhibitor free of metabolically mediated drug interactions: metabolic studies in human in vitro systems. J. Clin. Pharmacol. 40, 1055 (2000).
    • (2000) J. Clin. Pharmacol , vol.40 , pp. 1055
    • McCormick, A.D.1
  • 24
    • 0036891228 scopus 로고    scopus 로고
    • No effect of rosuvastatin on the pharmacokinetics of digoxin in healthy volunteers
    • Martin, P.D., Kemp, J., Dane, A.L., Warwick, M.J. & Schneck, D.W. No effect of rosuvastatin on the pharmacokinetics of digoxin in healthy volunteers. J. Clin. Pharmacol. 42, 1352-1357 (2002).
    • (2002) J. Clin. Pharmacol , vol.42 , pp. 1352-1357
    • Martin, P.D.1    Kemp, J.2    Dane, A.L.3    Warwick, M.J.4    Schneck, D.W.5
  • 26
    • 33750192677 scopus 로고    scopus 로고
    • Biliary secretion of rosuvastatin and bile acids in humans during the absorption phase
    • Bergman, E. et al. Biliary secretion of rosuvastatin and bile acids in humans during the absorption phase. Eur. J. Pharm. Sci. 29, 205-214 (2006).
    • (2006) Eur. J. Pharm. Sci , vol.29 , pp. 205-214
    • Bergman, E.1
  • 27
    • 33747884712 scopus 로고    scopus 로고
    • Role of BCRP 421C>A polymorphism on rosuvastatin pharmacokinetics in healthy Chinese males
    • Zhang, W. et al. Role of BCRP 421C>A polymorphism on rosuvastatin pharmacokinetics in healthy Chinese males. Clin. Chim. Acta 373, 99-103 (2006).
    • (2006) Clin. Chim. Acta , vol.373 , pp. 99-103
    • Zhang, W.1
  • 28
    • 25844458977 scopus 로고    scopus 로고
    • Rosuvastatin pharmacokinetics and pharmacogenetics in white and Asian subjects residing in the same environment
    • Lee, E. et al. Rosuvastatin pharmacokinetics and pharmacogenetics in white and Asian subjects residing in the same environment. Clin. Pharmacol. Ther. 78, 330-341 (2005).
    • (2005) Clin. Pharmacol. Ther , vol.78 , pp. 330-341
    • Lee, E.1
  • 29
    • 0012901790 scopus 로고
    • Pharmacological modification of bilirubin conjugation in the newborn
    • Catz, C. & Yaffe, S.J. Pharmacological modification of bilirubin conjugation in the newborn. Am. J. Dis. Child. 104, 516-517 (1962).
    • (1962) Am. J. Dis. Child , vol.104 , pp. 516-517
    • Catz, C.1    Yaffe, S.J.2
  • 30
    • 0032791711 scopus 로고    scopus 로고
    • Expression and inducibility of the human bilirubin UDP-glucuronosyltransferase UGT1A1 in liver and cultured primary hepatocytes: Evidence for both genetic and environmental influences
    • Ritter, J.K., Kessler, F.K., Thompson, M.T., Grove, A.D., Auyeung, D.J. & Fisher, R.A. Expression and inducibility of the human bilirubin UDP-glucuronosyltransferase UGT1A1 in liver and cultured primary hepatocytes: evidence for both genetic and environmental influences. Hepatology 30, 476-484 (1999).
    • (1999) Hepatology , vol.30 , pp. 476-484
    • Ritter, J.K.1    Kessler, F.K.2    Thompson, M.T.3    Grove, A.D.4    Auyeung, D.J.5    Fisher, R.A.6
  • 31
    • 0033774170 scopus 로고    scopus 로고
    • Recent advances in bilirubin metabolism research: The molecular mechanism of hepatocyte bilirubin transport and its clinical relevance
    • Kamisako, T. et al. Recent advances in bilirubin metabolism research: the molecular mechanism of hepatocyte bilirubin transport and its clinical relevance. J. Gastroenterol. 35, 659-664 (2000).
    • (2000) J. Gastroenterol , vol.35 , pp. 659-664
    • Kamisako, T.1
  • 33
    • 0035971239 scopus 로고    scopus 로고
    • Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6
    • Cui, Y., König, J., Leier, I., Buchholz, U. & Keppler, D. Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6. J. Biol. Chem. 276, 9626-9630 (2001).
    • (2001) J. Biol. Chem , vol.276 , pp. 9626-9630
    • Cui, Y.1    König, J.2    Leier, I.3    Buchholz, U.4    Keppler, D.5
  • 34
    • 0037907742 scopus 로고    scopus 로고
    • Role of organic anion-transporting polypeptides OATP-A OATP1B1 and OATP-8, in the human placenta-maternal tandem excretory pathway for foetal bilirubin
    • Briz, O., Serrano, M.A., Macias, R.R., Gonzalez-Gallego, J. & Marin, J.J.G. Role of organic anion-transporting polypeptides OATP-A OATP1B1 and OATP-8, in the human placenta-maternal tandem excretory pathway for foetal bilirubin. Biochem. J. 371, 897-905 (2003).
    • (2003) Biochem. J , vol.371 , pp. 897-905
    • Briz, O.1    Serrano, M.A.2    Macias, R.R.3    Gonzalez-Gallego, J.4    Marin, J.J.G.5
  • 35
    • 7744241812 scopus 로고    scopus 로고
    • Inhibition of human organic anion transporting polypeptide OATP 1B1 as a mechanism of drug-induced hyperbilirubinemia
    • Campbella, S.D., de Moraisa, S.M. & Xu, J.J. Inhibition of human organic anion transporting polypeptide OATP 1B1 as a mechanism of drug-induced hyperbilirubinemia. Chem. Biol. Interact. 150, 179-187 (2004).
    • (2004) Chem. Biol. Interact , vol.150 , pp. 179-187
    • Campbella, S.D.1    de Moraisa, S.M.2    Xu, J.J.3
  • 36
    • 20244380070 scopus 로고    scopus 로고
    • Influence of common variants in the pharmacokinetic genes (OATP-C, UGT1A1, and MRP2) on serum bilirubin levels in healthy subjects
    • Ieiri, I. et al. Influence of common variants in the pharmacokinetic genes (OATP-C, UGT1A1, and MRP2) on serum bilirubin levels in healthy subjects. Hepatol. Res. 30, 91-95 (2004).
    • (2004) Hepatol. Res , vol.30 , pp. 91-95
    • Ieiri, I.1
  • 37
    • 15344341734 scopus 로고    scopus 로고
    • Differential interaction of 3-hydroxy-3- methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1
    • Chen, C. et al. Differential interaction of 3-hydroxy-3- methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1. Drug Metab. Dispos. 33, 537-546 (2005).
    • (2005) Drug Metab. Dispos , vol.33 , pp. 537-546
    • Chen, C.1
  • 38
    • 1342265867 scopus 로고    scopus 로고
    • Inhibition of organic anion transporting polypeptide-mediated hepatic uptake is the major determinant in the pharmacokinetic interaction between bosentan and cyclosporin A in the rat
    • Treiber, A., Schneiter, R., Delahaye, S. & Clozel, M. Inhibition of organic anion transporting polypeptide-mediated hepatic uptake is the major determinant in the pharmacokinetic interaction between bosentan and cyclosporin A in the rat. J. Pharmacol. Exp. Ther. 308, 1121-1129 (2004).
    • (2004) J. Pharmacol. Exp. Ther , vol.308 , pp. 1121-1129
    • Treiber, A.1    Schneiter, R.2    Delahaye, S.3    Clozel, M.4
  • 39
    • 0036159433 scopus 로고    scopus 로고
    • Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine
    • Dresser, G.K. et al. Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine. Clin. Pharmacol. Ther. 71, 11-20 (2002).
    • (2002) Clin. Pharmacol. Ther , vol.71 , pp. 11-20
    • Dresser, G.K.1
  • 40
    • 13944275994 scopus 로고    scopus 로고
    • Effect of grapefruit juice volume on the reduction of fexofenadine bioavailability: Possible role of organic anion transporting polypeptides
    • Dresser, G.K., Kim, R.B. & Bailey, D.G. Effect of grapefruit juice volume on the reduction of fexofenadine bioavailability: possible role of organic anion transporting polypeptides. Clin. Pharmacol. Ther. 77, 170-177 (2005).
    • (2005) Clin. Pharmacol. Ther , vol.77 , pp. 170-177
    • Dresser, G.K.1    Kim, R.B.2    Bailey, D.G.3
  • 41
    • 27544453625 scopus 로고    scopus 로고
    • Flavonoids as a novel class of human organic anion-transporting polypeptide OATP1B1 (OATP-C) modulators
    • Wang, X., Wolkoff, A.W. & Morris, M.E. Flavonoids as a novel class of human organic anion-transporting polypeptide OATP1B1 (OATP-C) modulators. Drug Metab. Dispos. 33, 1666-1672 (2005).
    • (2005) Drug Metab. Dispos , vol.33 , pp. 1666-1672
    • Wang, X.1    Wolkoff, A.W.2    Morris, M.E.3
  • 42
    • 0028861660 scopus 로고
    • Detection of CYP2C9 polymorphism based on the polymerase chain reaction in Chinese
    • Wang, S.L., Huang, J., Lai, M.D. & Tsai, J.J. Detection of CYP2C9 polymorphism based on the polymerase chain reaction in Chinese. Pharmacogenetics 5, 37-42 (1995).
    • (1995) Pharmacogenetics , vol.5 , pp. 37-42
    • Wang, S.L.1    Huang, J.2    Lai, M.D.3    Tsai, J.J.4
  • 43
    • 11044234992 scopus 로고    scopus 로고
    • Lornoxicam pharmacokinetics in relation to cytochrome P450 2C9 genotype
    • Zhang, Y., Zhong, D., Si, D., Guo, Y., Chen, X. & Zhou, H. Lornoxicam pharmacokinetics in relation to cytochrome P450 2C9 genotype. Br. J. Clin. Pharmacol. 59, 14-17 (2005).
    • (2005) Br. J. Clin. Pharmacol , vol.59 , pp. 14-17
    • Zhang, Y.1    Zhong, D.2    Si, D.3    Guo, Y.4    Chen, X.5    Zhou, H.6
  • 44
    • 0035071957 scopus 로고    scopus 로고
    • A new statistical method for haplotype reconstruction from population data
    • Stephens, M., Smith, N.J. & Donnelly, P. A new statistical method for haplotype reconstruction from population data. Am. J. Hum. Genet. 68, 978-989 (2001).
    • (2001) Am. J. Hum. Genet , vol.68 , pp. 978-989
    • Stephens, M.1    Smith, N.J.2    Donnelly, P.3


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