In vivo imaging of the metabotropic glutamate receptor 1 (mGluR1) with Positron Emission Tomography: Recent advance and perspective

Current Medicinal Chemistry

Volumn 21, Issue 1, 2014, Pages 113-123

  Li, Songye ^a   Huang, Yiyun ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Evaluation; Metabotropic glutamate receptor; MGlu1; Positron emission tomography; Radioligand; Synthesis

Indexed keywords

FITM F 18; FPIT F 18; FPTQ F 18; FTIDC F 18; ITMM C 11; JNJ 16259685; JNJ 16567083 C 11; LY 2428703 C 11; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR ANTAGONIST; MK1312 F 18; MMTP C 11; RADIOPHARMACEUTICAL AGENT; TRACER; UNCLASSIFIED DRUG; YM 202074 C 11;

AREA UNDER THE CURVE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BINDING ASSAY; BLOOD BRAIN BARRIER; BODY TEMPERATURE; BRAIN HOMOGENATE; BRAIN SLICE; BRAIN TISSUE; CEREBELLUM; CINGULATE GYRUS; CORPUS STRIATUM; DISSOCIATION CONSTANT; DISTRIBUTION VOLUME; DRUG BINDING; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG SCREENING; DRUG STRUCTURE; DRUG UPTAKE; HAPLORHINI; HIPPOCAMPUS; HUMAN; IC 50; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; KINETICS; LIPOPHILICITY; NEUROPATHIC PAIN; NONHUMAN; PONS; POSITRON EMISSION TOMOGRAPHY; PUTAMEN; RADIOACTIVITY; RECEPTOR OCCUPANCY; SIGNAL TRANSDUCTION; STILLE REACTION; THALAMUS; TISSUE HOMOGENATE;

ANIMALS; BRAIN; CENTRAL NERVOUS SYSTEM DISEASES; HUMANS; LIGANDS; POSITRON-EMISSION TOMOGRAPHY; PROTEIN TRANSPORT; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 84889590530     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/09298673113209990217     Document Type: Article

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