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Volumn 10, Issue 12, 2013, Pages 1633-1651

Polymeric colloidal particulate systems: Intelligent tools for intracellular targeting of antileishmanial cargos

Author keywords

Active targeting; Human leishmaniasis; Immunotherapy; Passive targeting; Polymeric nano microparticles; Vaccines

Indexed keywords

ALBUMIN MICROSPHERE; ALGINIC ACID; AMAROGENTIN; AMPHOTERICIN B; ANDROGRAPHOLIDE; ANTILEISHMANIAL AGENT; BETA ESCIN; BIOPOLYMER; CHITOSAN; GAMMA INTERFERON; GELATIN; HAMYCIN; HARMINE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 12; LICOCHALCONE A; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MEGLUMINE ANTIMONATE; MILTEFOSINE; NANOCARRIER; PAROMOMYCIN; PENTAMIDINE; PLUMBAGIN; POLYLACTIC ACID; POLYMER; STARCH; STIBOGLUCONATE SODIUM; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG; ANTIPROTOZOAL AGENT; COLLOID; DRUG CARRIER;

EID: 84889066451     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2013.838216     Document Type: Review
Times cited : (21)

References (137)
  • 1
    • 0033517487 scopus 로고    scopus 로고
    • Leishmaniasis
    • DOI 10.1016/S0140-6736(98)10178-2
    • Herwaldt BL. Leishmaniasis. Lancet 1999;354(9185):1191-9 (Pubitemid 29460458)
    • (1999) Lancet , vol.354 , Issue.9185 , pp. 1191-1199
    • Herwaldt, B.L.1
  • 4
    • 74049122035 scopus 로고    scopus 로고
    • Drug resistance in visceral leishmaniasis
    • Maltezou HC. Drug resistance in visceral leishmaniasis. J Biomed Biotechnol 2010;2010:617521
    • (2010) J Biomed Biotechnol , vol.2010 , pp. 617521
    • Maltezou, H.C.1
  • 5
    • 70350630449 scopus 로고    scopus 로고
    • Current status and perspectives of the immunotherapy of leishmaniasis
    • El-On J. Current status and perspectives of the immunotherapy of leishmaniasis. Isr Med Assoc J 2009;11(10):623-8
    • (2009) Isr Med Assoc J , vol.11 , Issue.10 , pp. 623-628
    • El-On, J.1
  • 6
    • 84857063791 scopus 로고    scopus 로고
    • Clinical features and epidemiology of cutaneous leishmaniasis and Leishmania major/HIV co-infection in Cameroon: Results of a large cross-sectional study
    • Ngouateu OB, Kollo P, Ravel C, et al. Clinical features and epidemiology of cutaneous leishmaniasis and Leishmania major/HIV co-infection in Cameroon: results of a large cross-sectional study. Trans R Soc Trop Med Hyg 2012;106(3):137-42
    • (2012) Trans R Soc Trop Med Hyg , vol.106 , Issue.3 , pp. 137-142
    • Ngouateu, O.B.1    Kollo, P.2    Ravel, C.3
  • 7
    • 79959822382 scopus 로고    scopus 로고
    • Predictors of visceral leishmaniasis relapse in HIV-infected patients: A systematic review
    • Cota GF, de Sousa MR, Rabello A. Predictors of visceral leishmaniasis relapse in HIV-infected patients: a systematic review. PLoS Negl Trop Dis 2011;5(6):e1153
    • (2011) PLoS Negl Trop Dis , vol.5 , Issue.6
    • Cota, G.F.1    De Sousa, M.R.2    Rabello, A.3
  • 8
    • 42649122581 scopus 로고    scopus 로고
    • Clinical developments in drug delivery nanotechnology
    • Forrest ML, Kwon GS. Clinical developments in drug delivery nanotechnology. Adv Drug Deliv Rev 2008;60(8):861-2
    • (2008) Adv Drug Deliv Rev , vol.60 , Issue.8 , pp. 861-862
    • Forrest, M.L.1    Kwon, G.S.2
  • 9
    • 78650046007 scopus 로고    scopus 로고
    • Emerging role of vesicular carriers for therapy of visceral leishmaniasis: Conventional versus novel
    • Kumar N, Gupta S, Dube A, et al. Emerging role of vesicular carriers for therapy of visceral leishmaniasis: conventional versus novel. Crit Rev Ther Drug Carrier Syst 2010;27(6):461-507
    • (2010) Crit Rev Ther Drug Carrier Syst , vol.27 , Issue.6 , pp. 461-507
    • Kumar, N.1    Gupta, S.2    Dube, A.3
  • 10
    • 34547901070 scopus 로고    scopus 로고
    • Parasitic diseases: Liposomes and polymeric nanoparticles versus lipid nanoparticles
    • DOI 10.1016/j.addr.2007.04.009, PII S0169409X07000452, Lipid Nanoparticles: Recent Advances
    • Date AA, Joshi MD, Patravale VB. Parasitic diseases: liposomes and polymeric nanoparticles versus lipid nanoparticles. Adv Drug Deliv Rev 2007;59(6):505-21 (Pubitemid 47259228)
    • (2007) Advanced Drug Delivery Reviews , vol.59 , Issue.6 , pp. 505-521
    • Date, A.A.1    Joshi, M.D.2    Patravale, V.B.3
  • 11
    • 83155164597 scopus 로고    scopus 로고
    • Leishmaniasis: Focus on the design of nanoparticulate vaccine delivery systems
    • Doroud D, Rafati S. Leishmaniasis: focus on the design of nanoparticulate vaccine delivery systems. Expert Rev Vaccines 2012;11(1):69-86
    • (2012) Expert Rev Vaccines , vol.11 , Issue.1 , pp. 69-86
    • Doroud, D.1    Rafati, S.2
  • 12
    • 78149474474 scopus 로고    scopus 로고
    • Biodistribution and tissue toxicity of amphotericin B in mice following multiple dose administration of a novel oral lipid-based formulation (iCo-009)
    • Gershkovich P, Sivak O, Wasan EK, et al. Biodistribution and tissue toxicity of amphotericin B in mice following multiple dose administration of a novel oral lipid-based formulation (iCo-009). J Antimicrob Chemother 2010;65(12):2610-13
    • (2010) J Antimicrob Chemother , vol.65 , Issue.12 , pp. 2610-2613
    • Gershkovich, P.1    Sivak, O.2    Wasan, E.K.3
  • 13
    • 34447504406 scopus 로고    scopus 로고
    • Antileishmanial efficacy of amphotericin B bearing emulsomes against experimental visceral leishmaniasis
    • DOI 10.1080/10611860701453836, PII 779727350
    • Gupta S, Dube A, Vyas SP. Antileishmanial efficacy of amphotericin B bearing emulsomes against experimental visceral leishmaniasis. J Drug Target 2007;15(6):437-44 (Pubitemid 47073059)
    • (2007) Journal of Drug Targeting , vol.15 , Issue.6 , pp. 437-444
    • Gupta, S.1    Dube, A.2    Vyas, S.P.3
  • 14
    • 78649958725 scopus 로고    scopus 로고
    • New delivery strategies for the old pentavalent antimonial drugs
    • Frezard F, Demicheli C. New delivery strategies for the old pentavalent antimonial drugs. Expert Opin Drug Deliv 2010;7(12):1343-58
    • (2010) Expert Opin Drug Deliv , vol.7 , Issue.12 , pp. 1343-1358
    • Frezard, F.1    Demicheli, C.2
  • 15
    • 0026533657 scopus 로고
    • The interaction of Leishmania species with macrophages
    • Alexander J, Russell DG. The interaction of Leishmania species with macrophages. Adv Parasitol 1992;31:175-254
    • (1992) Adv Parasitol , vol.31 , pp. 175-254
    • Alexander, J.1    Russell, D.G.2
  • 16
    • 0346131227 scopus 로고    scopus 로고
    • The cell cycle of parasitic protozoa: Potential for chemotherapeutic exploitation
    • Hammarton TC, Mottram JC, Doerig C. The cell cycle of parasitic protozoa: potential for chemotherapeutic exploitation. Prog Cell Cycle Res 2003;5:91-101
    • (2003) Prog Cell Cycle Res , vol.5 , pp. 91-101
    • Hammarton, T.C.1    Mottram, J.C.2    Doerig, C.3
  • 17
    • 36448961645 scopus 로고    scopus 로고
    • Engulfment of apoptotic cells: Signals for a good meal
    • DOI 10.1038/nri2214, PII NRI2214
    • Ravichandran KS, Lorenz U. Engulfment of apoptotic cells: signals for a good meal. Nat Rev Immunol 2007;7(12):964-74 (Pubitemid 350166061)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.12 , pp. 964-974
    • Ravichandran, K.S.1    Lorenz, U.2
  • 18
    • 84863841734 scopus 로고    scopus 로고
    • Receptor-mediated phagocytosis of Leishmania: Implications for intracellular survival
    • Ueno N, Wilson ME. Receptor-mediated phagocytosis of Leishmania: implications for intracellular survival. Trends Parasitol 2012;28(8):335-44
    • (2012) Trends Parasitol , vol.28 , Issue.8 , pp. 335-344
    • Ueno, N.1    Wilson, M.E.2
  • 19
    • 0036853070 scopus 로고    scopus 로고
    • Evasion of innate immunity by parasitic protozoa
    • DOI 10.1038/ni1102-1041
    • Sacks D, Sher A. Evasion of innate immunity by parasitic protozoa. Nat Immunol 2002;3(11):1041-7 (Pubitemid 35363655)
    • (2002) Nature Immunology , vol.3 , Issue.11 , pp. 1041-1047
    • Sacks, D.1    Sher, A.2
  • 20
    • 4444326819 scopus 로고    scopus 로고
    • Surface determinants of Leishmania parasites and their role in infectivity in the mammalian host
    • DOI 10.2174/1566524043360069
    • Naderer T, Vince JE, McConville MJ. Surface determinants of Leishmania parasites and their role in infectivity in the mammalian host. Curr Mol Med 2004;4(6):649-65 (Pubitemid 39172369)
    • (2004) Current Molecular Medicine , vol.4 , Issue.6 , pp. 649-665
    • Naderer, T.1    Vince, J.E.2    McConville, M.J.3
  • 21
    • 0034825692 scopus 로고    scopus 로고
    • Life in vacuoles - Nutrient acquisition by Leishmania amastigotes
    • DOI 10.1016/S0020-7519(01)00259-4, PII S0020751901002594
    • Burchmore RJ, Barrett MP. Life in vacuoles-nutrient acquisition by Leishmania amastigotes. Int J Parasitol 2001;31(12):1311-20 (Pubitemid 32868711)
    • (2001) International Journal for Parasitology , vol.31 , Issue.12 , pp. 1311-1320
    • Burchmore, R.J.S.1    Barrett, M.P.2
  • 22
    • 31144454859 scopus 로고    scopus 로고
    • Mimicry of apoptotic cells by exposing phosphatidylserine participates in the establishment of amastigotes of Leishmania (L) amazonensis in mammalian hosts
    • Wanderley JL, Moreira ME, Benjamin A, et al. Mimicry of apoptotic cells by exposing phosphatidylserine participates in the establishment of amastigotes of Leishmania (L) amazonensis in mammalian hosts. J Immunol 2006;176(3):1834-9 (Pubitemid 43134328)
    • (2006) Journal of Immunology , vol.176 , Issue.3 , pp. 1834-1839
    • Wanderley, J.L.M.1    Moreira, M.E.C.2    Benjamin, A.3    Bonomo, A.C.4    Barcinski, M.A.5
  • 23
    • 33846456287 scopus 로고    scopus 로고
    • Immunopathogenesis of Leishmania infections
    • Yurdakul P. Immunopathogenesis of Leishmania infections. Mikrobiyol Bul 2005;39(3):363-81
    • (2005) Mikrobiyol Bul , vol.39 , Issue.3 , pp. 363-381
    • Yurdakul, P.1
  • 24
    • 0025326712 scopus 로고
    • Tumor necrosis factor-α in combination with interferon-γ, but not with interleukin 4 activates murine macrophages for elimination of Leishmania major amastigotes
    • DOI 10.1002/eji.1830200528
    • Bogdan C, Moll H, Solbach W, et al. Tumor necrosis factor-alpha in combination with interferon-gamma, but not with interleukin 4 activates murine macrophages for elimination of Leishmania major amastigotes. Eur J Immunol 1990;20(5):1131-5 (Pubitemid 20206069)
    • (1990) European Journal of Immunology , vol.20 , Issue.5 , pp. 1131-1135
    • Bogdan, C.1    Moll, H.2    Solbach, W.3    Rollinghoff, M.4
  • 25
    • 0036831673 scopus 로고    scopus 로고
    • The immunology of susceptibility and resistance to Leishmania major in mice
    • DOI 10.1038/nri933
    • Sacks D, Noben-Trauth N. The immunology of susceptibility and resistance to Leishmania major in mice. Nat Rev Immunol 2002;2(11):845-58 (Pubitemid 37328707)
    • (2002) Nature Reviews Immunology , vol.2 , Issue.11 , pp. 845-858
    • Sacks, D.1    Noben-Trauth, N.2
  • 26
    • 0343446135 scopus 로고    scopus 로고
    • Tuftsin-bearing liposomes in treatment of macrophage-based infections
    • DOI 10.1016/S0169-409X(99)00061-7, PII S0169409X99000617
    • Agrawal AK, Gupta CM. Tuftsin-bearing liposomes in treatment of macrophage-based infections. Adv Drug Deliv Rev 2000;41(2):135-46 (Pubitemid 30122954)
    • (2000) Advanced Drug Delivery Reviews , vol.41 , Issue.2 , pp. 135-146
    • Agrawal, A.K.1    Gupta, C.M.2
  • 30
    • 84856287868 scopus 로고    scopus 로고
    • Lipid nanoparticles containing oryzalin for the treatment of leishmaniasis
    • Lopes R, Eleuterio CV, Goncalves LM, et al. Lipid nanoparticles containing oryzalin for the treatment of leishmaniasis. Eur J Pharm Sci 2012;45(4):442-50
    • (2012) Eur J Pharm Sci , vol.45 , Issue.4 , pp. 442-450
    • Lopes, R.1    Eleuterio, C.V.2    Goncalves, L.M.3
  • 31
    • 74849088082 scopus 로고    scopus 로고
    • Bisnaphthalimidopropyl derivatives as inhibitors of Leishmania SIR2 related protein 1
    • Tavares J, Ouaissi A, Kong Thoo Lin P, et al. Bisnaphthalimidopropyl derivatives as inhibitors of Leishmania SIR2 related protein 1. ChemMedChem 2010;5(1):140-7
    • (2010) ChemMedChem , vol.5 , Issue.1 , pp. 140-147
    • Tavares, J.1    Ouaissi, A.2    Kong Thoo Lin, P.3
  • 32
    • 0026529706 scopus 로고
    • Potential of doxorubicin as an antileishmanial agent
    • Sett R, Basu N, Ghosh AK, et al. Potential of doxorubicin as an antileishmanial agent. J Parasitol 1992;78(2):350-4
    • (1992) J Parasitol , vol.78 , Issue.2 , pp. 350-354
    • Sett, R.1    Basu, N.2    Ghosh, A.K.3
  • 33
    • 0035164509 scopus 로고    scopus 로고
    • Antileishmanial activities of aphidicolin and its semisynthetic derivatives
    • DOI 10.1128/AAC.45.1.288-292.2001
    • Kayser O, Kiderlen AF, Bertels S, et al. Antileishmanial activities of aphidicolin and its semisynthetic derivatives. Antimicrob Agents Chemother 2001;45(1):288-92 (Pubitemid 32039128)
    • (2001) Antimicrobial Agents and Chemotherapy , vol.45 , Issue.1 , pp. 288-292
    • Kayser, O.1    Kiderlen, A.F.2    Bertels, S.3    Siems, K.4
  • 34
    • 84868022360 scopus 로고    scopus 로고
    • Peptidomimetic and organometallic derivatives of primaquine active against Leishmania infantum
    • Vale-Costa S, Vale N, Matos J, et al. Peptidomimetic and organometallic derivatives of primaquine active against Leishmania infantum. Antimicrob Agents Chemother 2012;56(11):5774-81
    • (2012) Antimicrob Agents Chemother , vol.56 , Issue.11 , pp. 5774-5781
    • Vale-Costa, S.1    Vale, N.2    Matos, J.3
  • 35
    • 0030043869 scopus 로고    scopus 로고
    • Activity of oral atovaquone alone and in combination with antimony in experimental visceral Leishmaniasis
    • Murray HW, Hariprashad J. Activity of oral atovaquone alone and in combination with antimony in experimental visceral leishmaniasis. Antimicrob Agents Chemother 1996;40(3):586-7 (Pubitemid 26071526)
    • (1996) Antimicrobial Agents and Chemotherapy , vol.40 , Issue.3 , pp. 586-587
    • Murray, H.W.1    Hariprashad, J.2
  • 37
    • 0042268077 scopus 로고    scopus 로고
    • Immunoenhancement combined with amphotericin B as treatment for experimental visceral leishmaniasis
    • DOI 10.1128/AAC.47.8.2513-2517.2003
    • Murray HW, Brooks EB, DeVecchio JL, et al. Immunoenhancement combined with amphotericin B as treatment for experimental visceral leishmaniasis. Antimicrob Agents Chemother 2003;47(8):2513-17 (Pubitemid 36919453)
    • (2003) Antimicrobial Agents and Chemotherapy , vol.47 , Issue.8 , pp. 2513-2517
    • Murray, H.W.1    Brooks, E.B.2    DeVecchio, J.L.3    Heinzel, F.P.4
  • 38
    • 0023131284 scopus 로고
    • Immunotherapy versus chemotherapy in localised cutaneous leishmaniasis
    • Convit J, Castellanos PL, Rondon A, et al. Immunotherapy versus chemotherapy in localised cutaneous leishmaniasis. Lancet 1987;1(8530):401-5 (Pubitemid 17016578)
    • (1987) Lancet , vol.1 , Issue.8530 , pp. 401-405
    • Convit, J.1    Castellanos, P.L.2    Rondon, A.3
  • 39
    • 0033013249 scopus 로고    scopus 로고
    • Therapeutic and prophylactic uses of Protein A in the control of Leishmania donovani infection in experimental animals
    • DOI 10.1016/S0165-2478(98)00102-3, PII S0165247898001023
    • Ghose AC, Mookerjee A, Sengupta K, et al. Therapeutic and prophylactic uses of protein A in the control of Leishmania donovani infection in experimental animals. Immunol Lett 1999;65(3):175-81 (Pubitemid 29074854)
    • (1999) Immunology Letters , vol.65 , Issue.3 , pp. 175-181
    • Ghose, A.C.1    Mookerjee, A.2    Sengupta, K.3    Ghosh, A.K.4    Dasgupta, S.5    Ray, P.K.6
  • 40
    • 0034076993 scopus 로고    scopus 로고
    • Activity of the novel immunomodulatory compound tucaresol against experimental visceral Leishmaniasis
    • DOI 10.1128/AAC.44.6.1494-1498.2000
    • Smith AC, Yardley V, Rhodes J, et al. Activity of the novel immunomodulatory compound tucaresol against experimental visceral leishmaniasis. Antimicrob Agents Chemother 2000;44(6):1494-8 (Pubitemid 30340784)
    • (2000) Antimicrobial Agents and Chemotherapy , vol.44 , Issue.6 , pp. 1494-1498
    • Smith, A.C.1    Yardley, V.2    Rhodes, J.3    Croft, S.L.4
  • 41
    • 0033057209 scopus 로고    scopus 로고
    • Treatment of experimental leishmaniasis with the immnnomodulators imiquimod and S-28463: Efficacy and mode of action
    • DOI 10.1086/314782
    • Buates S, Matlashewski G. Treatment of experimental leishmaniasis with the immunomodulators imiquimod and S- 28463: efficacy and mode of action. J Infect Dis 1999;179(6):1485-94 (Pubitemid 29246599)
    • (1999) Journal of Infectious Diseases , vol.179 , Issue.6 , pp. 1485-1494
    • Buates, S.1    Matlashewski, G.2
  • 42
    • 84856287418 scopus 로고    scopus 로고
    • Current treatment of leishmaniasis: A review
    • Monzote L. Current treatment of leishmaniasis: a review. Open Antimicrob Agents J 2009;1:9-19
    • (2009) Open Antimicrob Agents J , vol.1 , pp. 9-19
    • Monzote, L.1
  • 44
    • 53049090855 scopus 로고    scopus 로고
    • Leishmaniasis: Drug resistance and natural products (review)
    • Polonio T, Efferth T. Leishmaniasis: drug resistance and natural products (review). Int J Mol Med 2008;22(3):277-86
    • (2008) Int J Mol Med , vol.22 , Issue.3 , pp. 277-286
    • Polonio, T.1    Efferth, T.2
  • 45
    • 34547615972 scopus 로고    scopus 로고
    • Role of the ABC transporter PRP1 (ABCC7) in pentamidine resistance in Leishmania amastigotes
    • DOI 10.1128/AAC.00404-07
    • Coelho AC, Messier N, Ouellette M, et al. Role of the ABC transporter PRP1 (ABCC7) in pentamidine resistance in Leishmania amastigotes. Antimicrob Agents Chemother 2007;51(8):3030-2 (Pubitemid 47206255)
    • (2007) Antimicrobial Agents and Chemotherapy , vol.51 , Issue.8 , pp. 3030-3032
    • Coelho, A.C.1    Messier, N.2    Ouellette, M.3    Cotrim, P.C.4
  • 46
    • 4544289321 scopus 로고    scopus 로고
    • Dual action of antimonial drugs on thiol redox metabolism in the human pathogen Leishmania donovani
    • DOI 10.1074/jbc.M405635200
    • Wyllie S, Cunningham ML, Fairlamb AH. Dual action of antimonial drugs on thiol redox metabolism in the human pathogen Leishmania donovani. J Biol Chem 2004;279(38):39925-32 (Pubitemid 39258265)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.38 , pp. 39925-39932
    • Wyllie, S.1    Cunningham, M.L.2    Fairlamb, A.H.3
  • 47
    • 34249787648 scopus 로고    scopus 로고
    • A novel ATP-binding cassette transporter from Leishmania is involved in transport of phosphatidylcholine analogues and resistance to alkyl-phospholipids
    • DOI 10.1111/j.1365-2958.2007.05653.x
    • Castanys-Munoz E, Alder-Baerens N, Pomorski T, et al. A novel ATP-binding cassette transporter from Leishmania is involved in transport of phosphatidylcholine analogues and resistance to alkyl-phospholipids. Mol Microbiol 2007;64(5):1141-53 (Pubitemid 46849008)
    • (2007) Molecular Microbiology , vol.64 , Issue.5 , pp. 1141-1153
    • Castanys-Munoz, E.1    Alder-Baerens, N.2    Pomorski, T.3    Gamarro, F.4    Castanys, S.5
  • 48
    • 0033151909 scopus 로고    scopus 로고
    • Cationic liposome-encapsulated antisense oligonucleotide mediates efficient killing of intracellular Leishmania
    • DOI 10.1042/0264-6021:3400393
    • Chakraborty R, Dasgupta D, Adhya S, et al. Cationic liposome-encapsulated antisense oligonucleotide mediates efficient killing of intracellular Leishmania. Biochem J 1999;340(Pt 2):393-6 (Pubitemid 29286557)
    • (1999) Biochemical Journal , vol.340 , Issue.2 , pp. 393-396
    • Chakraborty, R.1    Dasgupta, D.2    Adhya, S.3    Basu, M.K.4
  • 49
    • 0033929012 scopus 로고    scopus 로고
    • Macrophage damage by Leishmania amazonensis cytolysin: Evidence of pore formation on cell membrane
    • DOI 10.1128/IAI.68.8.4578-4584.2000
    • Noronha FS, Cruz JS, Beirao PS, et al. Macrophage damage by Leishmania amazonensis cytolysin: evidence of pore formation on cell membrane. Infect Immun 2000;68(8):4578-84 (Pubitemid 30497726)
    • (2000) Infection and Immunity , vol.68 , Issue.8 , pp. 4578-4584
    • Noronha, F.S.M.1    Cruz, J.S.2    Beirao, P.S.L.3    Horta, M.F.4
  • 50
    • 76049089675 scopus 로고    scopus 로고
    • Changes in macrophage membrane properties during early Leishmania amazonensis infection differ from those observed during established infection and are partially explained by phagocytosis
    • Quintana E, Torres Y, Alvarez C, et al. Changes in macrophage membrane properties during early Leishmania amazonensis infection differ from those observed during established infection and are partially explained by phagocytosis. Exp Parasitol 2010;124(3):258-64
    • (2010) Exp Parasitol , vol.124 , Issue.3 , pp. 258-264
    • Quintana, E.1    Torres, Y.2    Alvarez, C.3
  • 51
    • 84864591348 scopus 로고    scopus 로고
    • Metabolic characterization of Leishmania major infection in activated and nonactivated macrophages
    • Lamour SD, Choi BS, Keun HC, et al. Metabolic characterization of Leishmania major infection in activated and nonactivated macrophages. J Proteome Res 2012;11(8):4211-22
    • (2012) J Proteome Res , vol.11 , Issue.8 , pp. 4211-4222
    • Lamour, S.D.1    Choi, B.S.2    Keun, H.C.3
  • 52
    • 79957787229 scopus 로고    scopus 로고
    • Nanoparticles containing nitric oxide donor with antileishmanial agent for synergistic effect against visceral leishmaniasis
    • Pandya S, Verma RK, Misra A. Nanoparticles containing nitric oxide donor with antileishmanial agent for synergistic effect against visceral leishmaniasis. J Biomed Nanotechnol 2011;7(1):213-15
    • (2011) J Biomed Nanotechnol , vol.7 , Issue.1 , pp. 213-215
    • Pandya, S.1    Verma, R.K.2    Misra, A.3
  • 53
    • 84856101986 scopus 로고    scopus 로고
    • Use of antimony in the treatment of leishmaniasis: Current status and future directions
    • Haldar AK, Sen P, Roy S. Use of antimony in the treatment of leishmaniasis: current status and future directions. Mol Biol Int 2011;2011:571242
    • (2011) Mol Biol Int , vol.2011 , pp. 571242
    • Haldar, A.K.1    Sen, P.2    Roy, S.3
  • 54
    • 84865975746 scopus 로고    scopus 로고
    • Transcriptomic signature of leishmania infected mice macrophages: A metabolic point of view
    • Rabhi I, Rabhi S, Ben-Othman R, et al. Transcriptomic signature of leishmania infected mice macrophages: a metabolic point of view. PLoS Negl Trop Dis 2012;6(8):e1763
    • (2012) PLoS Negl Trop Dis , vol.6 , Issue.8
    • Rabhi, I.1    Rabhi, S.2    Ben-Othman, R.3
  • 55
    • 0037846500 scopus 로고    scopus 로고
    • The parasite-specific trypanothione metabolism of trypanosoma and leishmania
    • DOI 10.1515/BC.2003.062
    • Krauth-Siegel RL, Meiering SK, Schmidt H. The parasite-specific trypanothione metabolism of trypanosoma and leishmania. Biol Chem 2003;384(4):539-49 (Pubitemid 36609170)
    • (2003) Biological Chemistry , vol.384 , Issue.4 , pp. 539-549
    • Krauth-Siegel, R.L.1    Meiering, S.K.2    Schmidt, H.3
  • 56
    • 0037470198 scopus 로고    scopus 로고
    • Myristoyl-CoA:Protein N-myristoyltransferase, an essential enzyme and potential drug target in kinetoplastid parasites
    • DOI 10.1074/jbc.M211391200
    • Price HP, Menon MR, Panethymitaki C, et al. Myristoyl-CoA:protein N-myristoyltransferase, an essential enzyme and potential drug target in kinetoplastid parasites. J Biol Chem 2003;278(9):7206-14 (Pubitemid 36800720)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.9 , pp. 7206-7214
    • Price, H.P.1    Menon, M.R.2    Panethymitaki, C.3    Goulding, D.4    McKean, P.G.5    Smith, D.F.6
  • 57
    • 0142258171 scopus 로고    scopus 로고
    • Leishmaniasis - Current chemotherapy and recent advances in the search for novel drugs
    • DOI 10.1016/j.pt.2003.09.008
    • Croft SL, Coombs GH. Leishmaniasis-current chemotherapy and recent advances in the search for novel drugs. Trends Parasitol 2003;19(11):502-8 (Pubitemid 37329659)
    • (2003) Trends in Parasitology , vol.19 , Issue.11 , pp. 502-508
    • Croft, S.L.1    Coombs, G.H.2
  • 58
    • 35348970995 scopus 로고    scopus 로고
    • Role of nanotechnology in pharmaceutical product development
    • DOI 10.1002/jps.20875
    • Devalapally H, Chakilam A, Amiji MM. Role of nanotechnology in pharmaceutical product development. J Pharm Sci 2007;96(10):2547-65 (Pubitemid 47603100)
    • (2007) Journal of Pharmaceutical Sciences , vol.96 , Issue.10 , pp. 2547-2565
    • Devalapally, H.1    Chakilam, A.2    Amiji, M.M.3
  • 59
    • 84863007517 scopus 로고    scopus 로고
    • Effects of PEG length and iron oxide nanoparticles size on reduced protein adsorption and non-specific uptake by macrophage cells
    • Ni F, Jiang L, Yang R, et al. Effects of PEG length and iron oxide nanoparticles size on reduced protein adsorption and non-specific uptake by macrophage cells. J Nanosci Nanotechnol 2012;12(3):2094-100
    • (2012) J Nanosci Nanotechnol , vol.12 , Issue.3 , pp. 2094-2100
    • Ni, F.1    Jiang, L.2    Yang, R.3
  • 60
    • 24644508450 scopus 로고    scopus 로고
    • Targeted drug delivery to macrophages in parasitic infections
    • DOI 10.2174/156720105774370177
    • Owais M, Gupta CM. Targeted drug delivery to macrophages in parasitic infections. Curr Drug Deliv 2005;2(4):311-18 (Pubitemid 41277764)
    • (2005) Current Drug Delivery , vol.2 , Issue.4 , pp. 311-318
    • Owais, M.1    Gupta, C.M.2
  • 61
    • 34249820576 scopus 로고    scopus 로고
    • Multifunctional nanocarriers
    • DOI 10.1016/j.addr.2006.09.009, PII S0169409X06001785, Particulate Nanomedicines
    • Torchilin VP. Multifunctional nanocarriers. Adv Drug Deliv Rev 2006;58(14):1532-55 (Pubitemid 44822608)
    • (2006) Advanced Drug Delivery Reviews , vol.58 , Issue.14 , pp. 1532-1555
    • Torchilin, V.P.1
  • 62
    • 0033927095 scopus 로고    scopus 로고
    • Target-based drug discovery for malaria, leishmaniassis, and trypanosomiasis
    • Werbovetz KA. Target-based drug discovery for malaria, leishmaniasis, and trypanosomiasis. Curr Med Chem 2000;7(8):835-60 (Pubitemid 30463246)
    • (2000) Current Medicinal Chemistry , vol.7 , Issue.8 , pp. 835-860
    • Werbovetz, K.A.1
  • 63
    • 44349131523 scopus 로고    scopus 로고
    • Mitochondrion of protozoan parasite emerges as potent therapeutic target: Exciting drugs are on the horizon
    • DOI 10.2174/138161208784041024
    • Sen N, Majumder HK. Mitochondrion of protozoan parasite emerges as potent therapeutic target: exciting drugs are on the horizon. Curr Pharm Des 2008;14(9):839-46 (Pubitemid 351736416)
    • (2008) Current Pharmaceutical Design , vol.14 , Issue.9 , pp. 839-846
    • Sen, N.1    Majumder, H.K.2
  • 64
    • 14144250911 scopus 로고    scopus 로고
    • Recent advances with liposomes as pharmaceutical carriers
    • DOI 10.1038/nrd1632
    • Torchilin VP. Recent advances with liposomes as pharmaceutical carriers. Nat Rev Drug Discov 2005;4(2):145-60 (Pubitemid 40282557)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.2 , pp. 145-160
    • Torchilin, V.P.1
  • 65
    • 0018387102 scopus 로고
    • Polycyanoacrylate nanocapsules as potential lysosomotropic carriers: Preparation, morphological and sorptive properties
    • Couvreur P, Kante B, Roland M, et al. Polycyanoacrylate nanocapsules as potential lysosomotropic carriers: preparation, morphological and sorptive properties. J Pharm Pharmacol 1979;31(5):331-2 (Pubitemid 9207599)
    • (1979) Journal of Pharmacy and Pharmacology , vol.31 , Issue.5 , pp. 331-332
    • Couvreur, P.1    Kante, B.2    Roland, M.3
  • 66
    • 0026507069 scopus 로고
    • Drug targeting with polyalkylcyanoacrylate nanoparticles: In vitro activity of primaquine-loaded nanoparticles against intracellular Leishmania donovani
    • Gaspar R, Opperdoes FR, Preat V, et al. Drug targeting with polyalkylcyanoacrylate nanoparticles: in vitro activity of primaquine-loaded nanoparticles against intracellular Leishmania donovani. Ann Trop Med Parasitol 1992;86(1):41-9
    • (1992) Ann Trop Med Parasitol , vol.86 , Issue.1 , pp. 41-49
    • Gaspar, R.1    Opperdoes, F.R.2    Preat, V.3
  • 67
    • 0026717840 scopus 로고
    • Macrophage activation by polymeric nanoparticles of polyalkylcyanoacrylates: Activity against intracellular Leishmania donovani associated with hydrogen peroxide production
    • Gaspar R, Preat V, Opperdoes FR, et al. Macrophage activation by polymeric nanoparticles of polyalkylcyanoacrylates: activity against intracellular Leishmania donovani associated with hydrogen peroxide production. Pharm Res 1992;9(6):782-7
    • (1992) Pharm Res , vol.9 , Issue.6 , pp. 782-787
    • Gaspar, R.1    Preat, V.2    Opperdoes, F.R.3
  • 68
    • 0031740361 scopus 로고    scopus 로고
    • Physicochemical characteristics of pentamidine-loaded polymethacrylate nanoparticles: Implication in the intracellular drug release in Leishmania major infected mice
    • Paul M, Durand R, Boulard Y, et al. Physicochemical characteristics of pentamidine-loaded polymethacrylate nanoparticles: implication in the intracellular drug release in Leishmania major infected mice. J Drug Target 1998;5(6):481-90 (Pubitemid 28499682)
    • (1998) Journal of Drug Targeting , vol.5 , Issue.6 , pp. 481-490
    • Paul, M.1    Durand, R.2    Boulard, Y.3    Fusai, T.4    Fernandez, C.5    Rivollet, D.6    Deniau, M.7    Astier, A.8
  • 69
    • 0028677596 scopus 로고
    • Action of pentamidine-bound nanoparticles against Leishmania on an in vivo model
    • Fusai T, Deniau M, Durand R, et al. Action of pentamidine-bound nanoparticles against Leishmania on an in vivo model. Parasite 1994;1(4):319-24
    • (1994) Parasite , vol.1 , Issue.4 , pp. 319-324
    • Fusai, T.1    Deniau, M.2    Durand, R.3
  • 71
    • 0030729577 scopus 로고    scopus 로고
    • Activity of pentamidine-loaded methacrylate nanoparticles against Leishmania infantum in a mouse model
    • DOI 10.1016/S0020-7519(97)00124-0, PII S0020751997001240
    • Durand R, Paul M, Rivollet D, et al. Activity of pentamidine-loaded methacrylate nanoparticles against Leishmania infantum in a mouse model. Int J Parasitol 1997;27(11):1361-7 (Pubitemid 27502238)
    • (1997) International Journal for Parasitology , vol.27 , Issue.11 , pp. 1361-1367
    • Durand, R.1    Paul, M.2    Rivollet, D.3    Houin, R.4    Astier, A.5    Deniau, M.6
  • 72
    • 0029067169 scopus 로고
    • In vitro study of the anti-leishmanial activity of biodegradable nanoparticles
    • Venier-Julienne MC, Vouldoukis I, Monjour L, et al. In vitro study of the anti-leishmanial activity of biodegradable nanoparticles. J Drug Target 1995;3(1):23-9
    • (1995) J Drug Target , vol.3 , Issue.1 , pp. 23-29
    • Venier-Julienne, M.C.1    Vouldoukis, I.2    Monjour, L.3
  • 73
    • 79957676878 scopus 로고    scopus 로고
    • Loading and release of amphotericin-B from biodegradable poly(lactic-co-glycolic acid) nanoparticles
    • Verma RK, Pandya S, Misra A. Loading and release of amphotericin-B from biodegradable poly(lactic-co-glycolic acid) nanoparticles. J Biomed Nanotechnol 2011;7(1):118-20
    • (2011) J Biomed Nanotechnol , vol.7 , Issue.1 , pp. 118-120
    • Verma, R.K.1    Pandya, S.2    Misra, A.3
  • 74
    • 84865136915 scopus 로고    scopus 로고
    • Evaluating the potential of polyester nanoparticles for per oral delivery of amphotericin B in treating visceral leishmaniasis
    • Italia JL, Kumar MN, Carter KC. Evaluating the potential of polyester nanoparticles for per oral delivery of amphotericin B in treating visceral leishmaniasis. J Biomed Nanotechnol 2012;8(4):695-702
    • (2012) J Biomed Nanotechnol , vol.8 , Issue.4 , pp. 695-702
    • Italia, J.L.1    Kumar, M.N.2    Carter, K.C.3
  • 75
    • 84864591366 scopus 로고    scopus 로고
    • PLGA nanoparticles and nanosuspensions with amphotericin B: Potent in vitro and in vivo alternatives to Fungizone and AmBisome
    • Van de Ven H, Paulussen C, Feijens PB, et al. PLGA nanoparticles and nanosuspensions with amphotericin B: potent in vitro and in vivo alternatives to Fungizone and AmBisome. J Control Release 2012;161(3):795-803
    • (2012) J Control Release , vol.161 , Issue.3 , pp. 795-803
    • Van De Ven, H.1    Paulussen, C.2    Feijens, P.B.3
  • 76
    • 80054713359 scopus 로고    scopus 로고
    • PLGA nanoparticles loaded with the antileishmanial saponin beta-aescin: Factor influence study and in vitro efficacy evaluation
    • Van de Ven H, Vermeersch M, Matheeussen A, et al. PLGA nanoparticles loaded with the antileishmanial saponin beta-aescin: factor influence study and in vitro efficacy evaluation. Int J Pharm 2011;420(1):122-32
    • (2011) Int J Pharm , vol.420 , Issue.1 , pp. 122-132
    • Van De Ven, H.1    Vermeersch, M.2    Matheeussen, A.3
  • 77
    • 80054682264 scopus 로고    scopus 로고
    • Intracellular drug delivery in Leishmania-infected macrophages: Evaluation of saponin-loaded PLGA nanoparticles
    • Van de Ven H, Vermeersch M, Vandenbroucke RE, et al. Intracellular drug delivery in Leishmania-infected macrophages: evaluation of saponin-loaded PLGA nanoparticles. J Drug Target 2012;20(2):142-54
    • (2012) J Drug Target , vol.20 , Issue.2 , pp. 142-154
    • Van De Ven, H.1    Vermeersch, M.2    Vandenbroucke, R.E.3
  • 78
    • 79954539322 scopus 로고    scopus 로고
    • Andrographolide nanoparticles in leishmaniasis: Characterization and in vitro evaluations
    • Roy P, Das S, Bera T, et al. Andrographolide nanoparticles in leishmaniasis: characterization and in vitro evaluations. Int J Nanomedicine 2010;5:1113-21
    • (2010) Int J Nanomedicine , vol.5 , pp. 1113-1121
    • Roy, P.1    Das, S.2    Bera, T.3
  • 79
    • 33745248421 scopus 로고    scopus 로고
    • Critical evaluation of the therapeutic potential of bassic acid incorporated in oil-in-water microemulsions and poly-D,L-lactide nanoparticles against experimental leishmaniasis
    • Lala S, Gupta S, Sahu NP, et al. Critical evaluation of the therapeutic potential of bassic acid incorporated in oil-in-water microemulsions and poly-D,L-lactide nanoparticles against experimental leishmaniasis. J Drug Target 2006;14(4):171-9
    • (2006) J Drug Target , vol.14 , Issue.4 , pp. 171-179
    • Lala, S.1    Gupta, S.2    Sahu, N.P.3
  • 80
    • 84871263911 scopus 로고    scopus 로고
    • Characterization and evaluation of BNIPDaoct-loaded PLGA nanoparticles for visceral leishmaniasis: In vitro and in vivo studies
    • Costa Lima SA, Resende M, Silvestre R, et al. Characterization and evaluation of BNIPDaoct-loaded PLGA nanoparticles for visceral leishmaniasis: in vitro and in vivo studies. Nanomedicine (Lond) 2012;7(12):1839-49
    • (2012) Nanomedicine (Lond) , vol.7 , Issue.12 , pp. 1839-1849
    • Costa Lima, S.A.1    Resende, M.2    Silvestre, R.3
  • 81
    • 0028131317 scopus 로고
    • Neoglycosylated liposomes as efficient ligands for the evaluation of specific sugar receptors on macrophages in health and in experimental leishmaniasis
    • Dutta M, Bandyopadhyay R, Basu MK. Neoglycosylated liposomes as efficient ligands for the evaluation of specific sugar receptors on macrophages in health and in experimental leishmaniasis. Parasitology 1994;109(Pt 2):139-47 (Pubitemid 24259797)
    • (1994) Parasitology , vol.109 , Issue.2 , pp. 139-147
    • Dutta, M.1    Bandyopadhyay, R.2    Basu, M.K.3
  • 82
    • 70449123609 scopus 로고    scopus 로고
    • Preparation, characterization and evaluation of targeting potential of amphotericin B-loaded engineered PLGA nanoparticles
    • Nahar M, Jain NK. Preparation, characterization and evaluation of targeting potential of amphotericin B-loaded engineered PLGA nanoparticles. Pharm Res 2009;26(12):2588-98
    • (2009) Pharm Res , vol.26 , Issue.12 , pp. 2588-2598
    • Nahar, M.1    Jain, N.K.2
  • 83
    • 79957779102 scopus 로고    scopus 로고
    • Development and characterization of doxorubicin loaded microparticles against experimental visceral leishmaniasis
    • Sharma S, Kumar P, Jaiswal A, et al. Development and characterization of doxorubicin loaded microparticles against experimental visceral leishmaniasis. J Biomed Nanotechnol 2011;7(1):135-6
    • (2011) J Biomed Nanotechnol , vol.7 , Issue.1 , pp. 135-136
    • Sharma, S.1    Kumar, P.2    Jaiswal, A.3
  • 86
    • 0027959516 scopus 로고
    • The activity and ultrastructural localization of primaquine-loaded poly (d, l-lactide) nanoparticles in Leishmania donovani infected mice
    • Rodrigues JM Jr, Croft SL, Fessi H, et al. The activity and ultrastructural localization of primaquine-loaded poly (d,l-lactide) nanoparticles in Leishmania donovani infected mice. Trop Med Parasitol 1994;45(3):223-8 (Pubitemid 24312029)
    • (1994) Tropical Medicine and Parasitology , vol.45 , Issue.3 , pp. 223-228
    • Rodrigues Jr., J.M.1    Croft, S.L.2    Fessi, H.3    Bories, C.4    Devissguet, J.-P.5
  • 88
    • 0031311892 scopus 로고    scopus 로고
    • Activity of pentamidine-loaded poly (D,L-lactide) nanoparticles against Leishmania infantum in a murine model
    • Durand R, Paul M, Rivollet D, et al. Activity of pentamidine-loaded poly (D, L-lactide) nanoparticles against Leishmania infantum in a murine model. Parasite 1997;4(4):331-6 (Pubitemid 127497638)
    • (1997) Parasite , vol.4 , Issue.4 , pp. 331-336
    • Durand, R.1    Paul, M.2    Rivollet, D.3    Fessi, H.4    Houin, R.5    Astier, A.6    Deniau, M.7
  • 89
    • 84859430685 scopus 로고    scopus 로고
    • In vitro evaluation of bisnaphthalimidopropyl derivatives loaded into pegylated nanoparticles against Leishmania infantum protozoa
    • Costa Lima S, Rodrigues V, Garrido J, et al. In vitro evaluation of bisnaphthalimidopropyl derivatives loaded into pegylated nanoparticles against Leishmania infantum protozoa. Int J Antimicrob Agents 2012;39(5):424-30
    • (2012) Int J Antimicrob Agents , vol.39 , Issue.5 , pp. 424-430
    • Costa Lima, S.1    Rodrigues, V.2    Garrido, J.3
  • 90
    • 1442301667 scopus 로고    scopus 로고
    • Delivery in vivo of 14-deoxy-11-oxoandrographolide, an antileishmanial agent, by different drug carriers
    • Lala S, Nandy AK, Mahato SB, et al. Delivery in vivo of 14-deoxy-11- oxoandrographolide, an antileishmanial agent, by different drug carriers. Indian J Biochem Biophys 2003;40(3):169-74 (Pubitemid 38292191)
    • (2003) Indian Journal of Biochemistry and Biophysics , vol.40 , Issue.3 , pp. 169-174
    • Lala, S.1    Nandy, A.K.2    Mahato, S.B.3    Basu, M.K.4
  • 91
    • 18744405403 scopus 로고    scopus 로고
    • Targeted delivery of arjunglucoside I using surface hydrophilic and hydrophobic nanocarriers to combat experimental leishmaniasis
    • DOI 10.1080/10611860500046732
    • Tyagi R, Lala S, Verma AK, et al. Targeted delivery of arjunglucoside I using surface hydrophilic and hydrophobic nanocarriers to combat experimental leishmaniasis. J Drug Target 2005;13(3):161-71 (Pubitemid 40668169)
    • (2005) Journal of Drug Targeting , vol.13 , Issue.3 , pp. 161-171
    • Tyagi, R.1    Lala, S.2    Verma, A.K.3    Nandy, A.K.4    Mahato, S.B.5    Maitra, A.6    Basu, M.K.7
  • 92
    • 0032794594 scopus 로고    scopus 로고
    • Improvement of in vitro and in vivo antileishmanial activities of 2',6'- dihydroxy-4'-methoxychalcone by entrapment in poly(D,L-lactide) nanoparticles
    • Torres-Santos EC, Rodrigues JM Jr, Moreira DL, et al. Improvement of in vitro and in vivo antileishmanial activities of 2', 6'-dihydroxy-4'- methoxychalcone by entrapment in poly (D,L-lactide) nanoparticles. Antimicrob Agents Chemother 1999;43(7):1776-8 (Pubitemid 29331268)
    • (1999) Antimicrobial Agents and Chemotherapy , vol.43 , Issue.7 , pp. 1776-1778
    • Torres-Santos, E.C.1    Rodrigues Jr., J.M.2    Moreira, D.L.3    Kaplan, M.A.C.4    Rossi-Bergmann, B.5
  • 93
    • 0038147016 scopus 로고    scopus 로고
    • Therapeutic evaluation of free and nanocapsule-encapsulated atovaquone in the treatment of murine visceral leishmaniasis
    • DOI 10.1179/000349803235001840
    • Cauchetier E, Paul M, Rivollet D, et al. Therapeutic evaluation of free and nanocapsule-encapsulated atovaquone in the treatment of murine visceral leishmaniasis. Ann Trop Med Parasitol 2003;97(3):259-68 (Pubitemid 36606358)
    • (2003) Annals of Tropical Medicine and Parasitology , vol.97 , Issue.3 , pp. 259-268
    • Cauchetier, E.1    Paul, M.2    Rivollet, D.3    Fessi, H.4    Astier, A.5    Deniau, M.6
  • 94
    • 0034908029 scopus 로고    scopus 로고
    • The antileishmanial properties of surface-modified, primaquine-loaded nanocapsules tested against intramacrophagic Leishmania donovani amastigotes in vitro
    • DOI 10.1080/00034980120067226
    • Heurtault B, Legrand P, Mosqueira V, et al. The antileishmanial properties of surface-modified, primaquine-loaded nanocapsules tested against intramacrophagic Leishmania donovani amastigotes in vitro. Ann Trop Med Parasitol 2001;95(5):529-33 (Pubitemid 32730487)
    • (2001) Annals of Tropical Medicine and Parasitology , vol.95 , Issue.5 , pp. 529-533
    • Heurtault, B.1    Legrand, P.2    Mosqueira, V.3    Devissaguet, J.-P.4    Barratt, G.5    Bories, C.6
  • 96
    • 79957680634 scopus 로고    scopus 로고
    • Design and development of Amphotericin B bearing polycaprolactone microparticles for macrophage targeting
    • Singh P, Gupta A, Jaiswal A, et al. Design and development of Amphotericin B bearing polycaprolactone microparticles for macrophage targeting. J Biomed Nanotechnol 2011;7(1):50-1
    • (2011) J Biomed Nanotechnol , vol.7 , Issue.1 , pp. 50-51
    • Singh, P.1    Gupta, A.2    Jaiswal, A.3
  • 99
    • 33645763934 scopus 로고    scopus 로고
    • Real-time reverse transcription-PCR quantification of cytokine mRNA expression in golden Syrian hamster infected with Leishmania infantum and treated with a new amphotericin B formulation
    • Rama Iniguez S, Dea-Ayuela MA, Sanchez-Brunete JA, et al. Real-time reverse transcription-PCR quantification of cytokine mRNA expression in golden Syrian hamster infected with Leishmania infantum and treated with a new amphotericin B formulation. Antimicrob Agents Chemother 2006;50(4):1195-201
    • (2006) Antimicrob Agents Chemother , vol.50 , Issue.4 , pp. 1195-1201
    • Rama Iniguez, S.1    Dea-Ayuela, M.A.2    Sanchez-Brunete, J.A.3
  • 100
    • 79952994973 scopus 로고    scopus 로고
    • Drug targeting to macrophages using paromomycin-loaded albumin microspheres for treatment of visceral leishmaniasis: An in vitro evaluation
    • Khan W, Kumar N. Drug targeting to macrophages using paromomycin-loaded albumin microspheres for treatment of visceral leishmaniasis: an in vitro evaluation. J Drug Target 2011;19(4):239-50
    • (2011) J Drug Target , vol.19 , Issue.4 , pp. 239-250
    • Khan, W.1    Kumar, N.2
  • 101
    • 75149163863 scopus 로고    scopus 로고
    • In vitro evaluation of surface functionalized gelatin nanoparticles for macrophage targeting in the therapy of visceral leishmaniasis
    • Nahar M, Dubey V, Mishra D, et al. In vitro evaluation of surface functionalized gelatin nanoparticles for macrophage targeting in the therapy of visceral leishmaniasis. J Drug Target 2010;18(2):93-105
    • (2010) J Drug Target , vol.18 , Issue.2 , pp. 93-105
    • Nahar, M.1    Dubey, V.2    Mishra, D.3
  • 102
    • 84875148599 scopus 로고    scopus 로고
    • Immunoadjuvant chemotherapy of visceral leishmaniasis in hamsters using amphotericin B-encapsulated nanoemulsion template-based chitosan nanocapsules
    • Asthana S, Jaiswal AK, Gupta PK, et al. Immunoadjuvant chemotherapy of visceral leishmaniasis in hamsters using amphotericin B-encapsulated nanoemulsion template-based chitosan nanocapsules. Antimicrob Agents Chemother 2013;57(4):1714-22
    • (2013) Antimicrob Agents Chemother , vol.57 , Issue.4 , pp. 1714-1722
    • Asthana, S.1    Jaiswal, A.K.2    Gupta, P.K.3
  • 103
    • 79955829562 scopus 로고    scopus 로고
    • Chitosan-based macrophage-mediated drug targeting for the treatment of experimental visceral leishmaniasis
    • Kunjachan S, Gupta S, Dwivedi AK, et al. Chitosan-based macrophage-mediated drug targeting for the treatment of experimental visceral leishmaniasis. J Microencapsul 2011;28(4):301-10
    • (2011) J Microencapsul , vol.28 , Issue.4 , pp. 301-310
    • Kunjachan, S.1    Gupta, S.2    Dwivedi, A.K.3
  • 104
    • 79957727187 scopus 로고    scopus 로고
    • Development and performance evaluation of alginate-capped amphotericin B lipid nanoconstructs against visceral leishmaniasis
    • Singodia D, Khare P, Dube A, et al. Development and performance evaluation of alginate-capped amphotericin B lipid nanoconstructs against visceral leishmaniasis. J Biomed Nanotechnol 2011;7(1):123-4
    • (2011) J Biomed Nanotechnol , vol.7 , Issue.1 , pp. 123-124
    • Singodia, D.1    Khare, P.2    Dube, A.3
  • 106
    • 0027212413 scopus 로고
    • Interferon-γ in starch microparticles: Nitric oxide-generating activity in vitro and antileishmanial effect in mice
    • DOI 10.1023/A:1018936522266
    • Degling L, Stjarnkvist P, Sjoholm I. Interferon-gamma in starch microparticles: nitric oxide-generating activity in vitro and antileishmanial effect in mice. Pharm Res 1993;10(6):783-90 (Pubitemid 23167557)
    • (1993) Pharmaceutical Research , vol.10 , Issue.6 , pp. 783-790
    • Degling, L.1    Stjarnkvist, P.2    Sjoholm, I.3
  • 107
    • 0023131595 scopus 로고
    • Biodegradable microspheres VI: Lysosomal release of covalently bound antiparasitic drugs from starch microparticles
    • DOI 10.1002/jps.2600760210
    • Laakso T, Stjarnkvist P, Sjoholm I. Biodegradable microspheres. VI: lysosomal release of covalently bound antiparasitic drugs from starch microparticles. J Pharm Sci 1987;76(2):134-40 (Pubitemid 17043679)
    • (1987) Journal of Pharmaceutical Sciences , vol.76 , Issue.2 , pp. 134-140
    • Laakso, T.1    Stjarnkvist, P.2    Sjoholm, I.3
  • 108
    • 0032796277 scopus 로고    scopus 로고
    • Evaluation of the in-vivo activity and toxicity of amarogentin, an antileishmanial agent, in both liposomal and niosomal forms
    • Medda S, Mukhopadhyay S, Basu MK. Evaluation of the in-vivo activity and toxicity of amarogentin, an antileishmanial agent, in both liposomal and niosomal forms. J Antimicrob Chemother 1999;44(6):791-4
    • (1999) J Antimicrob Chemother , vol.44 , Issue.6 , pp. 791-794
    • Medda, S.1    Mukhopadhyay, S.2    Basu, M.K.3
  • 109
    • 0036968461 scopus 로고    scopus 로고
    • Quercetin: Critical evaluation as an antileishmanial agent in vivo in hamsters using different vesicular delivery modes
    • DOI 10.1080/106118021000072681
    • Sarkar S, Mandal S, Sinha J, et al. Quercetin: critical evaluation as an antileishmanial agent in vivo in hamsters using different vesicular delivery modes. J Drug Target 2002;10(8):573-8 (Pubitemid 36124356)
    • (2002) Journal of Drug Targeting , vol.10 , Issue.8 , pp. 573-578
    • Sarkar, S.1    Mandal, S.2    Sinha, J.3    Mukhopadhyay, S.4    Das, N.5    Basu, M.K.6
  • 111
    • 4444272379 scopus 로고    scopus 로고
    • Macrophage specific drug delivery in experimental leishmaniasis
    • DOI 10.2174/1566524043360186
    • Basu MK, Lala S. Macrophage specific drug delivery in experimental leishmaniasis. Curr Mol Med 2004;4(6):681-9 (Pubitemid 39172370)
    • (2004) Current Molecular Medicine , vol.4 , Issue.6 , pp. 681-689
    • Basu, M.K.1    Lala, S.2
  • 112
    • 84858773500 scopus 로고    scopus 로고
    • Leishmaniasis: Prevention, parasite detection and treatment
    • Kobets T, Grekov I, Lipoldova M. Leishmaniasis: prevention, parasite detection and treatment. Curr Med Chem 2012;19(10):1443-74
    • (2012) Curr Med Chem , vol.19 , Issue.10 , pp. 1443-1474
    • Kobets, T.1    Grekov, I.2    Lipoldova, M.3
  • 113
    • 33846847777 scopus 로고    scopus 로고
    • Leishmania vaccines: Progress and problems
    • Kedzierski L, Zhu Y, Handman E. Leishmania vaccines: progress and problems. Parasitology 2006;133(Suppl):S87-112
    • (2006) Parasitology , vol.133 , Issue.SUPPL.
    • Kedzierski, L.1    Zhu, Y.2    Handman, E.3
  • 114
    • 0025730382 scopus 로고
    • Biodegradable microparticles as controlled release antigen delivery systems
    • O'Hagan DT, Rahman D, McGee JP, et al. Biodegradable microparticles as controlled release antigen delivery systems. Immunology 1991;73(2):239-42
    • (1991) Immunology , vol.73 , Issue.2 , pp. 239-242
    • O'hagan, D.T.1    Rahman, D.2    McGee, J.P.3
  • 115
    • 84872596121 scopus 로고    scopus 로고
    • Micro/nanoparticle adjuvants for antileishmanial vaccines: Present and future trends
    • Badiee A, Heravi Shargh V, Khamesipour A, et al. Micro/nanoparticle adjuvants for antileishmanial vaccines: present and future trends. Vaccine 2013;31(5):735-49
    • (2013) Vaccine , vol.31 , Issue.5 , pp. 735-749
    • Badiee, A.1    Heravi Shargh, V.2    Khamesipour, A.3
  • 116
    • 15244360555 scopus 로고    scopus 로고
    • Current vaccine adjuvants: An overview of a diverse class
    • Kensil CR, Mo AX, Truneh A. Current vaccine adjuvants: an overview of a diverse class. Front Biosci 2004;9:2972-88
    • (2004) Front Biosci , vol.9 , pp. 2972-2988
    • Kensil, C.R.1    Mo, A.X.2    Truneh, A.3
  • 117
    • 78650767560 scopus 로고    scopus 로고
    • Immunization against leishmaniasis by PLGA nanospheres loaded with an experimental autoclaved Leishmania major (ALM) and Quillaja saponins
    • Tafaghodi M, Eskandari M, Kharazizadeh M, et al. Immunization against leishmaniasis by PLGA nanospheres loaded with an experimental autoclaved Leishmania major (ALM) and Quillaja saponins. Trop Biomed 2010;27(3):639-50
    • (2010) Trop Biomed , vol.27 , Issue.3 , pp. 639-650
    • Tafaghodi, M.1    Eskandari, M.2    Kharazizadeh, M.3
  • 118
    • 79956217016 scopus 로고    scopus 로고
    • Immunization against leishmaniasis by PLGA nanospheres encapsulated with autoclaved Leishmania major (ALM) and CpG-ODN
    • Tafaghodi M, Khamesipour A, Jaafari MR. Immunization against leishmaniasis by PLGA nanospheres encapsulated with autoclaved Leishmania major (ALM) and CpG-ODN. Parasitol Res 2011;108(5):1265-73
    • (2011) Parasitol Res , vol.108 , Issue.5 , pp. 1265-1273
    • Tafaghodi, M.1    Khamesipour, A.2    Jaafari, M.R.3
  • 119
    • 80052412990 scopus 로고    scopus 로고
    • Alginate microspheres encapsulated with autoclaved Leishmania major (ALM) and CpG-ODN induced partial protection and enhanced immune response against murine model of leishmaniasis
    • Tafaghodi M, Eskandari M, Khamesipour A, et al. Alginate microspheres encapsulated with autoclaved Leishmania major (ALM) and CpG-ODN induced partial protection and enhanced immune response against murine model of leishmaniasis. Exp Parasitol 2011;129(2):107-14
    • (2011) Exp Parasitol , vol.129 , Issue.2 , pp. 107-114
    • Tafaghodi, M.1    Eskandari, M.2    Khamesipour, A.3
  • 120
    • 80053316871 scopus 로고    scopus 로고
    • Nanovaccine for leishmaniasis: Preparation of chitosan nanoparticles containing Leishmania superoxide dismutase and evaluation of its immunogenicity in BALB/c mice
    • Danesh-Bahreini MA, Shokri J, Samiei A, et al. Nanovaccine for leishmaniasis: preparation of chitosan nanoparticles containing Leishmania superoxide dismutase and evaluation of its immunogenicity in BALB/c mice. Int J Nanomedicine 2011;6:835-42
    • (2011) Int J Nanomedicine , vol.6 , pp. 835-842
    • Danesh-Bahreini, M.A.1    Shokri, J.2    Samiei, A.3
  • 121
    • 18944378937 scopus 로고    scopus 로고
    • Kinetoplastid membrane protein-11 DNA vaccination induces complete protection against both pentavalent antimonial-sensitive and -resistant strains of Leishmania donovani that correlates with inducible nitric oxide synthase activity and IL-4 generation: Evidence for mixed Th1- and Th2-like responses in visceral leishmaniasis
    • Basu R, Bhaumik S, Basu JM, et al. Kinetoplastid membrane protein-11 DNA vaccination induces complete protection against both pentavalent antimonial-sensitive and - resistant strains of Leishmania donovani that correlates with inducible nitric oxide synthase activity and IL-4 generation: evidence for mixed Th1- and Th2-like responses in visceral leishmaniasis. J Immunol 2005;174(11):7160-71 (Pubitemid 40705683)
    • (2005) Journal of Immunology , vol.174 , Issue.11 , pp. 7160-7171
    • Basu, R.1    Bhaumik, S.2    Basu, J.M.3    Naskar, K.4    De, T.5    Roy, S.6
  • 122
    • 84866749418 scopus 로고    scopus 로고
    • Towards development of novel immunization strategies against leishmaniasis using PLGA nanoparticles loaded with kinetoplastid membrane protein-11
    • Santos DM, Carneiro MW, de Moura TR, et al. Towards development of novel immunization strategies against leishmaniasis using PLGA nanoparticles loaded with kinetoplastid membrane protein-11. Int J Nanomedicine 2012;7:2115-27
    • (2012) Int J Nanomedicine , vol.7 , pp. 2115-2127
    • Santos, D.M.1    Carneiro, M.W.2    De Moura, T.R.3
  • 123
    • 33847219040 scopus 로고    scopus 로고
    • Molecular mechanisms of antimony resistance in Leishmania
    • Ashutosh Sundar S, Goyal N. Molecular mechanisms of antimony resistance in Leishmania. J Med Microbiol 2007;56(Pt 2):143-53
    • (2007) J Med Microbiol , vol.56 , Issue.PART 2 , pp. 143-153
    • Ashutosh Sundar, S.1    Goyal, N.2
  • 124
    • 3242748862 scopus 로고    scopus 로고
    • Reduction of anti-leishmanial pentavalent antimonial drugs by a parasite-specific thiol-dependent reductase, TDR1
    • DOI 10.1042/BJ20040283
    • Denton H, McGregor JC, Coombs GH. Reduction of anti-leishmanial pentavalent antimonial drugs by a parasite-specific thiol-dependent reductase, TDR1. Biochem J 2004;381(Pt 2):405-12 (Pubitemid 38969684)
    • (2004) Biochemical Journal , vol.381 , Issue.2 , pp. 405-412
    • Denton, H.1    McGregor, J.C.2    Coombs, G.H.3
  • 125
    • 0029059922 scopus 로고
    • Kinetics and molecular characteristics of arginine transport by Leishmania donovani promastigotes
    • Kandpal M, Fouce RB, Pal A, et al. Kinetics and molecular characteristics of arginine transport by Leishmania donovani promastigotes. Mol Biochem Parasitol 1995;71(2):193-201
    • (1995) Mol Biochem Parasitol , vol.71 , Issue.2 , pp. 193-201
    • Kandpal, M.1    Fouce, R.B.2    Pal, A.3
  • 126
    • 80051817554 scopus 로고    scopus 로고
    • The 8-aminoquinoline analogue sitamaquine causes oxidative stress in Leishmania donovani promastigotes by targeting succinate dehydrogenase
    • Carvalho L, Luque-Ortega JR, Lopez-Martin C, et al. The 8-aminoquinoline analogue sitamaquine causes oxidative stress in Leishmania donovani promastigotes by targeting succinate dehydrogenase. Antimicrob Agents Chemother 2011;55(9):4204-10
    • (2011) Antimicrob Agents Chemother , vol.55 , Issue.9 , pp. 4204-4210
    • Carvalho, L.1    Luque-Ortega, J.R.2    Lopez-Martin, C.3
  • 127
    • 0036894232 scopus 로고    scopus 로고
    • Resistance to pentamidine in Leishmania mexicana involves exclusion of the drug from the mitochondrion
    • DOI 10.1128/AAC.46.12.3731-3738.2002
    • Basselin M, Denise H, Coombs GH, et al. Resistance to pentamidine in Leishmania mexicana involves exclusion of the drug from the mitochondrion. Antimicrob Agents Chemother 2002;46(12):3731-8 (Pubitemid 35403244)
    • (2002) Antimicrobial Agents and Chemotherapy , vol.46 , Issue.12 , pp. 3731-3738
    • Basselin, M.1    Denise, H.2    Coombs, G.H.3    Barrett, M.P.4
  • 129
    • 60649092132 scopus 로고    scopus 로고
    • Altered sterol profile induced in Leishmania amazonensis by a natural dihydroxymethoxylated chalcone
    • Torres-Santos EC, Sampaio-Santos MI, Buckner FS, et al. Altered sterol profile induced in Leishmania amazonensis by a natural dihydroxymethoxylated chalcone. J Antimicrob Chemother 2009;63(3):469-72
    • (2009) J Antimicrob Chemother , vol.63 , Issue.3 , pp. 469-472
    • Torres-Santos, E.C.1    Sampaio-Santos, M.I.2    Buckner, F.S.3
  • 130
    • 33645755408 scopus 로고    scopus 로고
    • Antitrypanosomal and antileishmanial activities of flavonoids and their analogues: In vitro, in vivo, structure-activity relationship, and quantitative structure-activity relationship studies
    • Tasdemir D, Kaiser M, Brun R, et al. Antitrypanosomal and antileishmanial activities of flavonoids and their analogues: in vitro, in vivo, structure-activity relationship, and quantitative structure-activity relationship studies. Antimicrob Agents Chemother 2006;50(4):1352-64
    • (2006) Antimicrob Agents Chemother , vol.50 , Issue.4 , pp. 1352-1364
    • Tasdemir, D.1    Kaiser, M.2    Brun, R.3
  • 131
    • 34548612902 scopus 로고    scopus 로고
    • In vitro activity of 10-deacetylbaccatin III against Leishmania donovani promastigotes and intracellular amastigotes
    • DOI 10.1055/s-2007-981579
    • Georgopoulou K, Smirlis D, Bisti S, et al. In vitro activity of 10-deacetylbaccatin III against Leishmania donovani promastigotes and intracellular amastigotes. Planta Med 2007;73(10):1081-8 (Pubitemid 47401293)
    • (2007) Planta Medica , vol.73 , Issue.10 , pp. 1081-1088
    • Georgopoulou, K.1    Smirlis, D.2    Bisti, S.3    Xingi, E.4    Skaltsounis, L.5    Soteriadou, K.6
  • 132
    • 0026787390 scopus 로고
    • Biological and chemical studies of Pera benensis, a Bolivian plant used in folk medicine as a treatment of cutaneous leishmaniasis
    • Fournet A, Angelo A, Munoz V, et al. Biological and chemical studies of Pera benensis, a Bolivian plant used in folk medicine as a treatment of cutaneous leishmaniasis. J Ethnopharmacol 1992;37(2):159-64
    • (1992) J Ethnopharmacol , vol.37 , Issue.2 , pp. 159-164
    • Fournet, A.1    Angelo, A.2    Munoz, V.3
  • 133
    • 12144255598 scopus 로고    scopus 로고
    • In vitro and in vivo anti-leishmanial activity of triterpenoid saponins isolated from Maesa balansae and some chemical derivatives
    • DOI 10.1021/jm031150y
    • Germonprez N, Maes L, Van Puyvelde L, et al. In vitro and in vivo anti-leishmanial activity of triterpenoid saponins isolated from Maesa balansae and some chemical derivatives. J Med Chem 2005;48(1):32-7 (Pubitemid 40105247)
    • (2005) Journal of Medicinal Chemistry , vol.48 , Issue.1 , pp. 32-37
    • Germonprez, N.1    Maes, L.2    Van Puyvelde, L.3    Van Tri, M.4    Tuan, D.A.5    De Kimpe, N.6
  • 134
    • 0028113980 scopus 로고
    • Mannose-coated liposomal hamycin in the treatment of experimental leishmaniasis in hamsters
    • DOI 10.1006/bmmb.1994.1050
    • Banerjee G, Bhaduri AN, Basu MK. Mannose-coated liposomal hamycin in the treatment of experimental leishmaniasis in hamsters. Biochem Med Metab Biol 1994;53(1):1-7 (Pubitemid 24339013)
    • (1994) Biochemical Medicine and Metabolic Biology , vol.53 , Issue.1 , pp. 1-7
    • Banerjee, G.1    Bhaduri, A.N.2    Basu, M.K.3
  • 135
    • 3042844195 scopus 로고    scopus 로고
    • Harmine: Evaluation of its antileishmanial properties in various vesicular delivery systems
    • DOI 10.1080/10611860410001712696
    • Lala S, Pramanick S, Mukhopadhyay S, et al. Harmine: evaluation of its antileishmanial properties in various vesicular delivery systems. J Drug Target 2004;12(3):165-75 (Pubitemid 38868164)
    • (2004) Journal of Drug Targeting , vol.12 , Issue.3 , pp. 165-175
    • Lala, S.1    Pramanick, S.2    Mukhopadhyay, S.3    Bandyopadhyay, S.4    Basu, M.K.5
  • 136
    • 0038268719 scopus 로고    scopus 로고
    • Phospholipid microspheres: A novel delivery mode for targeting antileishmanial agent in experimental leishmaniasis
    • DOI 10.1080/1061186031000119101
    • Medda S, Jaisankar P, Manna RK, et al. Phospholipid microspheres: a novel delivery mode for targeting antileishmanial agent in experimental leishmaniasis. J Drug Target 2003;11(2):123-8 (Pubitemid 36869186)
    • (2003) Journal of Drug Targeting , vol.11 , Issue.2 , pp. 123-128
    • Medda, S.1    Jaisankar, P.2    Manna, R.K.3    Pal, B.4    Giri, V.S.5    Basu, M.K.6


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