Development and characterization of doxorubicin loaded microparticles against experimental visceral leishmaniasis

Journal of Biomedical Nanotechnology

Volumn 7, Issue 1, 2011, Pages 135-136

  Sharma, Sheeshpal ^a   Kumar, Pankaj ^a   Jaiswal, Anil ^b   Dube, Anuradha ^b   Gupta, Swati ^a  

^a ISF COLLEGE OF PHARMACY   (India)

^b CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Doxorubicin; Microparticles; Targeting; Visceral leishmaniasis

Indexed keywords

DOXORUBICIN; MACROPHAGE TARGETING; MICRO-PARTICLES; SIDE EFFECT; TARGETED DELIVERY; TARGETING; VISCERAL LEISHMANIASIS;

CHEMOTHERAPY;

MACROPHAGES;

DOXORUBICIN; MANNAN; POLYGLACTIN; DRUG CARRIER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC THERAPY; ANTIPROTOZOAL ACTIVITY; ARTICLE; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG SCREENING; HAMSTER; LEISHMANIA DONOVANI; MICROENCAPSULATION; NONHUMAN; PARTICLE SIZE; RAT; VISCERAL LEISHMANIASIS; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; LEISHMANIA; MICROCAPSULE; PHYSIOLOGY; SYNTHESIS;

CAPSULES; CELL SURVIVAL; DOXORUBICIN; DRUG CARRIERS; LEISHMANIA;

EID: 79957779102     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2011.1237     Document Type: Article

References (4)

1. A. Dube, N. Singh, and S. Sundar, Refractoriness to the treatment of sodium stibogluconate in Indian kala-azar field isolates persist in in vitro and in vivo experimental models. Parasitol Res. 96, 216 (2005).
2. M. Tunkay, S. Calis, H. S. Kas, M. T. Ercan, and A. A. Hincal, Diclofenac sodium incorporated PLGA (50:50) microspheres: Formulation consideration and in vitro/in vivo evaluation. Int. J. Pharm. 195, 179 (2000).
3. A. M. Le Ray, S. Chiffoleau, P. Iooss, G. Grimandi, A. Gouyette, G. Daculsi, and C. Merle, Vancomycin encapsulation in biodegradable poly(epsiloncaprolactone) microparticles for bone implantation. Influence of the formulation process on size, drug loading, in vitro release and cytocompatibility. Biomaterials 24, 443 (2003).
4. S. Gupta and S. P. Vyas, Development and characterization of AmB bearing emulsomes for the passive and active macrophage targeting. J. Drug Target. 15, 206 (2007).