In vitro evaluation of bisnaphthalimidopropyl derivatives loaded into pegylated nanoparticles against Leishmania infantum protozoa

International Journal of Antimicrobial Agents

Volumn 39, Issue 5, 2012, Pages 424-430

  Costa Lima, Sofia ^a   Rodrigues, Vasco ^a   Garrido, Jorge ^b,c   Borges, Fernanda ^b   Kong Thoo Lin, Paul ^d   Cordeiro Da Silva, Anabela ^a,b  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c INSTITUTO SUPERIOR DE ENGENHARIA DO PORTO   (Portugal)

^d ROBERT GORDON UNIVERSITY   (United Kingdom)

Author keywords

Bisnaphthalimidopropyl derivatives; Human THP 1 macrophages; Leishmania infantum; Murine J774 macrophages; PEG PLA nanoparticles

Indexed keywords

ANTILEISHMANIAL AGENT; BISNAPHTHALIMIDOPROPYL DERIVATIVE; LUCIFERASE; NANOPARTICLE; POLYLACTIC ACID; UNCLASSIFIED DRUG;

AMASTIGOTE; ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; BIODEGRADATION; CELL ENCAPSULATION; CELL METABOLISM; CELL VIABILITY; CONTROLLED STUDY; DRUG COATING; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG STRUCTURE; HOST CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LEISHMANIA INFANTUM; MACROPHAGE; MAMMAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VISCERAL LEISHMANIASIS;

ANIMALS; ANTIPROTOZOAL AGENTS; CELL LINE; CELL SURVIVAL; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HUMANS; LACTIC ACID; LEISHMANIA INFANTUM; MACROPHAGES; MICE; NANOPARTICLES; POLYMERS; QUINOLONES; TETRAZOLIUM SALTS; THIAZOLES;

EID: 84859430685     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2012.01.003     Document Type: Article

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