Harmine: Evaluation of its antileishmanial properties in various vesicular delivery systems

Journal of Drug Targeting

Volumn 12, Issue 3, 2004, Pages 165-175

  Lala, Sanchaita ^a   Pramanick, Swapan ^a   Mukhopadhyay, Sibabrata ^a   Bandyopadhyay, Santu ^a   Basu, Mukul Kumar ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

Antileishmanial activity; Harmine; Liposomes; Nanoparticles; Niosomes

Indexed keywords

ANTIPROTOZOAL AGENT; BETA CARBOLINE DERIVATIVE; HARMINE; LIPOSOME; NANOPARTICLE; NIOSOME; PEGANUM HARMALA EXTRACT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROTOZOAL ACTIVITY; APOPTOSIS; ARTICLE; BIOCHEMISTRY; CELL CYCLE; CELL DEATH; CELL DIVISION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG ISOLATION; FLOW CYTOMETRY; HAMSTER; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INTERCALATION COMPLEX; KIDNEY FUNCTION; LEISHMANIA DONOVANI; LEISHMANIASIS; LIVER FUNCTION; LIVER TOXICITY; MEMBRANE DAMAGE; NEPHROTOXICITY; NONHUMAN; PARASITE VIRULENCE; PRIORITY JOURNAL; PROMASTIGOTE; SPLEEN;

ANIMALS; APOPTOSIS; CELL CYCLE; CELLS, CULTURED; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HARMINE; KIDNEY; LEISHMANIA DONOVANI; LEISHMANIASIS; LEUKOCYTES, MONONUCLEAR; LIPOSOMES; LIVER; MESOCRICETUS; MICROSCOPY, CONFOCAL; PARTICLE SIZE; SPLEEN; TRYPANOCIDAL AGENTS;

EID: 3042844195     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/10611860410001712696     Document Type: Article

References (37)

1. Abe, F., NagaFuji, S., Yamauchi, T., Okabe, H., Maki, J., Higo, H., Akahane, H., Aguilar, A., Jimenez-Estrada, M. and Reyes-Chilpa, R. (2002) "Trypanocidal constituents in plants 1. Evaluation of some Mexican plants for their trypanocidal activity and active constituents in Guaco, roots of Aristolochia taliscana", Biol. Pharm Bull. 25(9), 1188-1197.
2. Airaksinen, M.M. and Kari, I. (1981) "Beta-carbolines, psychoactive compounds in the mammalian body. Part II. Effects", Med. Biol. 59(4), 190-211.
3. Baillie, A.J., Florence, A.T., Hume, L.R., Muirhead, G.T. and Rogerson, A. (1985) "The preparation and properties of niosome - non-ionic surfactant vesicles", J. Phar. Pharmacol. 37(12), 863-868.
4. Bessey, O.A., Lowry, O.H. and Brock, M. (1946) "A method for rapid determination of alkaline phosphatase with five cubic millimetres of serum", J. Biol. Chem. 164, 321-329, Cited in: Bergmeyer, H.Y., ed, Methods of Enzymatic Analysis, 2nd Edition, (Academic Press, New York), Vol. 1, pp. 856-864.
5. Boeira, J.M., da Silva, J., Erdtmann, B. and Henriques, J.A. (2001) "Genotoxic effects of the alkaloids harman and harmine assessed by comet assay and chromosome aberration test in mammalian cells in vitro", Pharmacol. Toxicol. 89(6), 287-294.
6. Boeira, J.M., Viana, A.F., Picada, J.N. and Henriques, J.A. (2002) "Genotoxic and recombinogenic activities of the two beta-carboline alkaloids harman and harmine in Saccharomyces cerevisiae", Mutat. Res. 500(1-2), 39-48.
7. Cui, Z. and Mumper, R.J. (2003) "Microparticles and nanoparticles as delivery systems for DNA vaccines", Crit. Rev. Ther. Drug Carrier Syst. 20(2-3), 103-137.
8. Das, N., Mahato, S.B., Naskar, K., Ghosh, B.K. and Basu, M.K. (1990) "Targeting of urea stibamine encapsulated in liposomes to reticuloendothelial system for the treatment of experimental leishmaniasis", Biochem. Med. Metab. Biol. 43, 133-139.
9. Gregoriadis, G. and Ryman, B.E. (1972) "Lysosomal localisation of β-fructofuranosidase containing liposomes injected into rats", Biochem. J. 12, 1020-1030.
10. Gurr, E. (1962) Staining Animal Tissues: Practical and Theoretical (Leonard Hill, London, United Kingdom).
11. Guterres, S.S., Fessi, H., Barratt, G., Devissaguet, J.P. and Puisieux, F. (1995) "Poly(DL-Lactide) nanocapsules containing diclofenac I. Formulation and stability study", Int. J. Pharm. 113, 57-63.
12. Ishida, J., Wang, H.K., Bastow, K.F., Hu, C.Q. and Lee, K.H. (1999) "Antitumor agents 201. Cytotoxicity of harmine and beta-cartboline analogs", Bioorg. Med. Chem. Lett. 9(23), 3319-3324.
13. Ishida, J., Wang, H.K., Oyama, M., Cosentino, M.L., Hu, C.Q. and Lee, K.H. (2001) "Anti-AIDS agents 46. Anti-HIV activity of harman, an anti-HIV principle from Symplocos setchuensis, and its derivatives", J. Nat. Prod. 64(7), 958-960.
14. Kreuter, J. (1996) "Nanoparticles and microparticles for drug and vaccine delivery", J. Anat. 189(Pt 3), 503-505.
15. Lala, S., Nandy, A.K., Mahato, S.B. and Basu, M.K. (2003) "Delivery in vivo of 14-deoxy-11-oxoandrographolide, an antileishmanial agent, by different drug carriers", Indian J. Biochem. Biophys. 40, 169-174.
16. Looker, D.L., Berens, R.L. and Marr, J.J. (1983) "Purine metabolism in Leishmania donovani amastigotes and promastigotes", Mol. Bio-Chem. Parasitol. 19, 15-28.
17. Ma, Z.Z., Hano, Y., Nomura, T. and Chen, Y.J. (2000) "Alkaloids and phenylpropanoids, from Peganum nigellastrum", Phytochemistry 53(8), 1075-1078.
18. Martin, B.S., Reutelingsperger, C.P., McGahon, A.J., Van Schiee, R.C.A.A., La Face, D.M. and Greenn, D.R. (1995) "Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of initiating stimulus inhibition by over expression of Bcl 2 and Abl", J. Exp. Med. 182, 1345-1350.
19. Molero, M.L., Hazen, M.J., Perez-Gorrono, A.I. and Stockert, J.C. (1995) "Simple beta-carboline alkaloids as nucleic acid fluorochromes", Acta Histochem. 97(2), 165-173.
20. Mukhopadhyay, S., Banerjee, S.K., Atal, C.K., Lin, L.-J. and Cordell, G.A. (1987) "Alkaloids of Corydalis govaniana", J. Nat. Prod. 50, 270-273.
21. Panyam, J. and Labhasetwar, V. (2003) "Biodegradable nanoparticles for drug and gene delivery to cells and tissues", Adv. Drugs Deliv. Rev. 55(3), 329-347.
22. Quintanar-Guerrero, D., Allemann, E., Fessi, H. and Doelker, E. (1998) "Preparation, techniques and mechanism of formation of biodegradable nanoparticles from preformed polymers", Drug Dev. Ind. Pharm. 24(12), 1113-1128.
23. Reitman, S. and Frankel, S. (1957) "A colorimetric method for the determination of serum oxaloacetic and glutamic pyruvic transaminases", Am. J. Clin. Pathol. 28, 56-63, Cited in: Giulbault, G.G, ed, Handbook of Enzymatic Methods of Analysis (Marcel Dekker, Inc., New York and Basel), 1976. pp. 121-123.
24. Rivas, P., Cassels, B.K., Morello, A. and Repetto, Y. (1999) "Effects of some beta-carboline alkaloids on intact Trypanosoma cruzi epimastigotes", Comp. Biol. Physiol. C. Pharmacol. Toxicol. Endocrinol. 122(1), 27-31.
25. Sakuma, S., Hayashi, M. and Akashi, M. (2001) "Design of nanoparticles composed of graft co-polymers for oral peptide delivery", Adv. Drug Deliv. Rev. 47(1), 21-37.
26. Sanchez-Ramos, J.R. (1991) "Banisterine and Parkinson's disease", Clin. Neuropharmacol. 14(5), 391-402.
27. Sarkar, S., Mandal, S., Sinha, J., Mukhopadhyay, S., Das, N. and Basu, M.K. (2003) "Quercetin: Critical evaluation as an antileishmanial agent in vivo in hamsters using different vesicular delivery modes", J. Drug Target. 10, 573-578.
28. Seyler, I., Morin, C., Barratt, G., Appel, M., Devissaguet, J.P. and Puisieux, F. (1995) "Induction of macrophage NO synthase by an immunomodulator entrapped within polymeric nanocapsules", Eur. J. Pharm Biopharm. 41(1), 49-54.
29. Shi, C.C., Liao, J.F. and Chen, C.F. (2001) "Spasmolytic affects of three harmala alkaloids on guinea-pig isolated trachea", Pharmacol. Toxicol. 89(5), 259-264.
30. Shi, C.C., Liao, J.F. and Chen, C.F. (2001) "Comparative study on the vasorelaxant effects of three harmala alkaloids in vitro", Jpn. J. Pharmacol. 85(3), 299-305.
31. Sinha, J., Raay, B., Das, N., Medda, S., Garai, S., Mahato, S.B. and Basu, M.K. (2002) "Bacopasaponin C: critical evaluation of antileishmanial properties in various delivery modes", Drug Deliv. 9, 55-62.
32. Sobhani, A.M., Ebrahim, S.A. and Mohmoudian, M. (2002) "An in vitro evaluation of human DNA topoisomerase I inhibition by Peganum harmala L. seeds extract and its beta-carboline alkaloids", J. Pharm. Phar. Sci. 5(1), 19-23.
33. Sourkes, T.L. (1999) "Rational hope in the early treatment of Parkinson's disease", Can. J. Physiol. Pharmacol. 77(6), 375-382.
34. Stauber, L.A., Franchino, E. and Grun, J. (1958) "An eight-day method for screening compounds against Leishmania donovani in golden hamster", J. Protozool. 5, 263-273.
35. Uezeno, T., Maruyama, W., Matsubara, K., Naoi, M., Shimizu, K., Saito, O., Ogawa, K., Mizukami, H., Hayase, N. and Shiono, H. (2001) "Norharman, an indoleamine-derived beta-carboline, but not Trp-P-2, a gamma carboline, induces apoptotic cell death in human neuroblastoma SH-SY5Y cells", J. Neural. Transm. 108(8-9), 943-953.
36. Vijayanathan, V., Thomas, T. and Thomas, T.J. (2002) "DNA nanoparticles and development of DNA delivery vehicles for gene therapy", Biochemistry 41(48), 4085-4094.
37. Yoshioka, T., Sternberg, B. and Florence, A.T. (1994) "Preparation and properties of vesicles (niosomes) of sorbitan monoesters (Span 20, 30, 60 and 80) and a sorbitan triester(Span 85 ", Int. J. Pharm. 105, 1-6.