Uncoupling of eNOS contributes to redox-sensitive leukocyte recruitment and microvascular leakage elicited by methylglyoxal

Biochemical Pharmacology

Volumn 86, Issue 12, 2013, Pages 1762-1774

  Su, Yang ^a   Qadri, Syed M ^a   Hossain, Mokarram ^a   Wu, Lingyun ^b   Liu, Lixin ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b LAKEHEAD UNIVERSITY   (Canada)

Author keywords

eNOS uncoupling; Leukocyte recruitment; Methylglyoxal; Microvascular permeability; Superoxide

Indexed keywords

ARGINASE; BIOPTERIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; METHYLGLYOXAL; N(G) NITROARGININE METHYL ESTER; REACTIVE OXYGEN METABOLITE; SEPIAPTERIN; SUPEROXIDE; TEMPOL; TETRAHYDROBIOPTERIN; SAPROPTERIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; CREMASTER MUSCLE; DIABETES MELLITUS; DIAPEDESIS; ENDOTHELIAL DYSFUNCTION; FLUORESCENCE IMAGING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VIVO STUDY; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; LEUKOCYTE ROLLING; MALE; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; OXIDATIVE STRESS; PRECURSOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; REDOX STRESS; UMBILICAL VEIN ENDOTHELIAL CELL; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CAPILLARY PERMEABILITY; CYTOLOGY; DRUG EFFECTS; LEUKOCYTE; METABOLISM; OXIDATION REDUCTION REACTION; SKELETAL MUSCLE;

ANIMALS; BIOPTERIN; CAPILLARY PERMEABILITY; LEUKOCYTES; MALE; MICE; MICE, INBRED C57BL; MUSCLE, SKELETAL; NITRIC OXIDE SYNTHASE TYPE III; OXIDATION-REDUCTION; PYRUVALDEHYDE; REACTIVE OXYGEN SPECIES;

EID: 84888877883     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.10.008     Document Type: Article

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