Tetrahydrobiopterin ameliorates hepatic ischemia-reperfusion injury by coupling with eNOS in mice

Journal of Surgical Research

Volumn 176, Issue 2, 2012, Pages

  Dai, Youguo ^a   Cui, Jin ^a   Cun, Yingli ^a   Shi, Anhua ^b  

^a KUNMING MEDICAL UNIVERSITY   (China)

^b YUNNAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Endothelial nitric oxide synthase; Hepatic ischemia reperfusion injury; Nitric oxide; Tetrahydrobiopterin

Indexed keywords

8 ISOPROSTANE; ALANINE AMINOTRANSFERASE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; SODIUM CHLORIDE; TETRAHYDROBIOPTERIN;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; LIVER FAILURE; LIVER ISCHEMIA; LIVER NECROSIS; MOUSE; NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; SURVIVAL; SURVIVAL RATE; WESTERN BLOTTING;

ALANINE TRANSAMINASE; ANIMALS; BIOPTERIN; DELAYED GRAFT FUNCTION; DINOPROST; LIVER; LIVER DISEASES; LIVER TRANSPLANTATION; MICE; MICE, INBRED STRAINS; NITRATES; NITRIC OXIDE SYNTHASE TYPE III; REPERFUSION INJURY; SUPEROXIDES; VITAMIN B 12;

EID: 84863985430     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2011.12.034     Document Type: Article

References (28)

1. I.H. Shaik, and R. Mehvar Cytochrome P450 induction by Phenobarbital exacerbates warm hepatic ischemia-reperfusion injury in rat livers Free Radic Res 44 2010 441
2. J.L. Zweier, J.T. Flaherty, and M.L. Weisfeldt Direct measurement of free radical generation following reperfusion of ischemic myocardium Proc Natl Acad Sci USA 84 1987 1404
3. M.A. Zaouali, H. Ben Abdennebi, and S. Padrissa-Altés Pharmacological strategies against cold ischemia reperfusion injury Expert Opin Pharmacother 11 2010 537
4. D.A. Shoskes, Y. Xie, and N.F. Gonzalez-Cadavid Nitric oxide synthase activity in renal ischemia-reperfusion injury in the rat: Implications for renal transplantation Transplantation 63 1997 495
5. M. Delgado-Esteban, A. Almeida, and J.M. Medina Tetrahydrobiopterin deficiency increases neuronal vulnerability to hypoxia J Neurochem 82 2002 1148
6. S. Milstien, and Z. Katusic Oxidation of tetrahydrobiopterin by peroxynitrite: Implications for vascular endothelial function Biochem Biophys Res Commun 263 1999 681
7. D.D. Koo, K.I. Welsh, and N.E. West Endothelial cell protection against ischemia-reperfusion injury by lecithinized superoxide dismutase Kidney Int 60 2001 786
8. M. Ishii, S. Shimizu, and S. Nawata Involvement of reactive oxygen species and nitric oxide in gastric ischemia-reperfusion injury in rats: Protective effect of tetrahydrobiopterin Dig Dis Sci 45 2000 93
9. R. Sucher, P. Gehwolf, and R. Oberhuber Tetrahydrobiopterin protects the kidney from ischemia-reperfusion injury Kidney Int 77 2010 681
10. M. Ono, Y. Sawa, and M. Ryugo BH4 peptide derivative from Bcl-xL attenuates ischemia/reperfusion injury thorough anti-apoptotic mechanism in rat hearts Eur J Cardiothorac Surg 27 2005 117
11. R.A. Schmid, S. Hillinger, and R. Walter The nitric oxide synthase cofactor tetrahydrobiopterin reduces allograft ischemia-reperfusion injury after lung transplantation J Thorc Cardiovasc Surg 118 1999 726
12. B. Thony, G. Auerbach, and N. Blau Tetrahydrobiopterin biosynthesis, regeneration and functions Biochem J 347 2000 1
13. J. Vasquez-Vivar, B. Kalyanaraman, and P. Martasek Superoxide generation by endothelial nitric oxide synthase: The influence of cofactors Proc Natl Acad Sci USA 95 1998 9220
14. D. Stuehr, S. Pou, and G.M. Rosen Oxygen reduction by nitricoxide synthases J Biol Chem 276 2000 14533
15. D.J. Stuehr Mammalian nitric oxide synthases Biochim Biophys Acta 1411 1999 217
16. P. Klatt, K. Schmidt, and D. Lehner Structural analysis of porcine brain nitric oxide synthase reveals a role for tetrahydrobiopterin and L-arginine in the formation of an SDS- resistant dimer EMBO J 14 1995 3687
17. E. Tzeng, T.R. Billiar, and P.D. Robbins Expression of human inducible nitric oxide synthase in a tetrahydrobiopterin (H4B) deficient cell line-H4B promotes assembly of enzyme subunits into an active enzyme Proc Natl Acad Sci USA 92 1995 11771
18. A. Reif, L.G. Frohlich, and P. Kotsonis Tetrahydrobiopterin inhibits monomerization and is consumed during catalysis in neuronal NO synthase J Biol Chem 274 1999 24921
19. S. Cai, N.J. Alp, and D. McDonald GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: Effects on nitric oxide synthase activity, protein levels and dimerization Cardiovasc Res 55 2002 838
20. K. Panda, R.J. Rosenfeld, and S. Ghosh Distinct dimer interaction and regulation in nitric-oxide synthase types I, II, and III J Biol Chem 277 2002 31020
21. E.T. Crockett, J.J. Galligan, and B.D. Uhal Protection of early phase hepatic ischemia-reperfusion injury by cholinergic agonists BMC Clin Pathol 6 2006 1
22. N.J. Alp, S. Mussa, and J. Khoo Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression J Clin Invest 112 2003 725
23. S. Kojima, S. Ona, and I. Iizuka Antioxidative activity of 5,6,7,8- tetrahydrobiopterin and its inhibitory effect on paraquat-induced cell toxicity in cultured rat hepatocytes Free Radic Res 23 1995 419
24. K. Michals-Matalon Sapropterin dihydrochloride, 6-R-L-erythro-5,6,7,8- tetrahydro- biopterin, in the treatment of phenylketonuria Expert Opin Investig Drugs 17 2008 245
25. J.L. Zweier, J.T. Flaherty, and M.L. Weisfeldt Direct measurement of free radical generation following reperfusion of ischemic myocardium Proc Natl Acad Sci USA 84 1987 1404
26. S. Shen Inhibition of luminol-enhanced chemiluminescence by reduced pterins Arch Biochem Biophys 310 1994 60
27. U. Mehlhorn, A. Krahwinkel, and H.J. Geissler Nitrotyrosine and 8-isoprostane formation indicate free radical-mediated injury in hearts of patients subjected to cardioplegia J Thorc Cardiovasc Surg 125 2003 178
28. F. Cosentino, and T.F. Luscher Tetrahydrobiopterin and endothelial nitric oxide synthase activity Cardiovasc Res 43 1999 274