Glyoxal causes inflammatory injury in human vascular endothelial cells

Biochemical and Biophysical Research Communications

Volumn 369, Issue 4, 2008, Pages 1155-1159

  Yamawaki, Hideyuki ^a   Hara, Yukio ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

Diabetes; Inflammation; Signal transduction; Vascular endothelium

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ADVANCED GLYCATION END PRODUCT; ANTIOXIDANT; CATALASE; CYCLOOXYGENASE 2; GLUCOSE; GLYOXAL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE N,N' ETHYLENEBIS(3 METHOXYSALICYLIDENEAMINE); MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; NITROPRUSSIDE SODIUM; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DIABETES MELLITUS; ENDOTHELIUM CELL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INFLAMMATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; VASCULAR ENDOTHELIUM;

ANTIOXIDANTS; CULLIN PROTEINS; CYCLOOXYGENASE 2; DIABETIC ANGIOPATHIES; ENDOTHELIUM, VASCULAR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; GLUCOSE; GLYCOSYLATION END PRODUCTS, ADVANCED; GLYOXAL; HUMANS; NITRIC OXIDE DONORS; ORGANOMETALLIC COMPOUNDS; PROTEIN KINASE INHIBITORS; SALICYLATES; SIGNAL TRANSDUCTION; VASCULITIS;

EID: 41149113282     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.03.020     Document Type: Article

References (34)

1. Bartnik M., Norhammar A., and Ryden L. Hyperglycaemia and cardiovascular disease. J. Intern. Med. 262 (2007) 145-156
2. Maiti R., and Agrawal N.K. Atherosclerosis in diabetes mellitus: role of inflammation. Ind. J. Med. Sci. 61 (2007) 292-306
3. Ross R. Atherosclerosis-an inflammatory disease. N. Engl. J. Med. 340 (1999) 115-126
4. Libby P. Inflammation in atherosclerosis. Nature 420 (2002) 868-874
5. Hartge M.M., Unger T., and Kintscher U. The endothelium and vascular inflammation in diabetes. Diab. Vasc. Dis. Res. 4 (2007) 84-88
6. Ono Y., Aoki S., Ohnishi K., Yasuda T., Kawano K., and Tsukada Y. Increased serum levels of advanced glycation end-products and diabetic complications. Diabetes Res. Clin. Pract. 41 (1998) 131-137
7. Kilhovd B.K., Berg T.J., Birkeland K.I., Thorsby P., and Hanssen K.F. Serum levels of advanced glycation end products are increased in patients with type 2 diabetes and coronary heart disease. Diabetes Care 22 (1999) 1543-1548
8. Aso Y., Inukai T., Tayama K., and Takemura Y. Serum concentrations of advanced glycation endproducts are associated with the development of atherosclerosis as well as diabetic microangiopathy in patients with type 2 diabetes. Acta Diabetol. 37 (2000) 87-92
9. Sheu M.L., Ho F.M., Yang R.S., Chao K.F., Lin W.W., Lin-Shiau S.Y., and Liu S.H. High glucose induces human endothelial cell apoptosis through a phosphoinositide 3-kinase-regulated cyclooxygenase-2 pathway. Arterioscler. Thromb. Vasc. Biol. 25 (2005) 539-545
10. 2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway. Cell Signal 18 (2006) 391-399
11. Zhang L., Zalewski A., Liu Y., Mazurek T., Cowan S., Martin J.L., Hofmann S.M., Vlassara H., and Shi Y. Diabetes-induced oxidative stress and low-grade inflammation in porcine coronary arteries. Circulation 108 (2003) 472-478
12. Srinivasan S., Hatley M.E., Bolick D.T., Palmer L.A., Edelstein D., Brownlee M., and Hedrick C.C. Hyperglycaemia-induced superoxide production decreases eNOS expression via AP-1 activation in aortic endothelial cells. Diabetologia 47 (2004) 1727-1734
13. Basta G., Lazzerini G., Massaro M., Simoncini T., Tanganelli P., Fu C., Kislinger T., Stern D.M., Schmidt A.M., and De Caterina R. Advanced glycation end products activate endothelium through signal-transduction receptor RAGE: a mechanism for amplification of inflammatory responses. Circulation 105 (2002) 816-822
14. Valencia J.V., Mone M., Koehne C., Rediske J., and Hughes T.E. Binding of receptor for advanced glycation end products (RAGE) ligands is not sufficient to induce inflammatory signals: lack of activity of endotoxin-free albumin-derived advanced glycation end products. Diabetologia 47 (2004) 844-852
15. Shinohara M., Thornalley P.J., Giardino I., Beisswenger P., Thorpe S.R., Onorato J., and Brownlee M. Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis. J. Clin. Invest. 101 (1998) 1142-1147
16. Akhand A.A., Hossain K., Kato M., Miyata T., Du J., Suzuki H., Kurokawa K., and Nakashima I. Glyoxal and methylglyoxal induce lyoxal and methyglyoxal induce aggregation and inactivation of ERK in human endothelial cells. Free Radic. Biol. Med. 31 (2001) 1228-1235
17. Akhand A.A., Hossain K., Mitsui H., Kato M., Miyata T., Inagi R., Du J., Takeda K., Kawamoto Y., Suzuki H., Kurokawa K., and Nakashima I. Glyoxal and methylglyoxal trigger distinct signals for map family kinases and caspase activation in human endothelial cells. Free Radic. Biol. Med. 31 (2001) 20-30
18. Lapolla A., Flamini R., Dalla Vedova A., Senesi A., Reitano R., Fedele D., Basso E., Seraglia R., and Traldi P. Glyoxal and methylglyoxal levels in diabetic patients: quantitative determination by a new GC/MS method. Clin. Chem. Lab Med. 41 (2003) 1166-1173
19. Yamawaki H., Pan S., Lee R.T., and Berk B.C. Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin-interacting protein in endothelial cells. J. Clin. Invest. 115 (2005) 733-738
20. Yamawaki H., and Iwai N. Cytotoxicity of water-soluble fullerene in vascular endothelial cells. Am. J. Physiol. Cell Physiol. 290 (2006) C1495-C1502
21. Moncada S., Palmer R.M., and Higgs E.A. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 43 (1991) 109-142
22. Rong Y., Doctrow S.R., Tocco G., and Baudry M. EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology. Proc. Natl. Acad. Sci. USA 96 (1999) 9897-9902
23. Samai M., Sharpe M.A., Gard P.R., and Chatterjee P.K. Comparison of the effects of the superoxide dismutase mimetics EUK-134 and tempol on paraquat-induced nephrotoxicity. Free Radic. Biol. Med. 43 (2007) 528-534
24. Gallicchio M., Rosa A.C., Benetti E., Collino M., Dianzani C., and Fantozzi R. Substance P-induced cyclooxygenase-2 expression in human umbilical vein endothelial cells. Br. J. Pharmacol. 147 (2006) 681-689
25. Wu G., Luo J., Rana J.S., Laham R., Sellke F.W., and Li J. Involvement of COX-2 in VEGF-induced angiogenesis via P38 and JNK pathways in vascular endothelial cells. Cardiovasc. Res. 69 (2006) 512-519
26. Park Y.S., Kim J., Misonou Y., Takamiya R., Takahashi M., Freeman M.R., and Taniguchi N. Acrolein induces cyclooxygenase-2 and prostaglandin production in human umbilical vein endothelial cells: roles of p38 MAP kinase. Arterioscler. Thromb. Vasc. Biol. 27 (2007) 1319-1325
27. Syeda F., Grosjean J., Houliston R.A., Keogh R.J., Carter T.D., Paleolog E., and Wheeler-Jones C.P. Cyclooxygenase-2 induction and prostacyclin release by protease-activated receptors in endothelial cells require cooperation between mitogen-activated protein kinase and NF-kappaB pathways. J. Biol. Chem. 281 (2006) 11792-11804
28. Eligini S., Stella Barbieri S., Cavalca V., Camera M., Brambilla M., De Franceschi M., Tremoli E., and Colli S. Diversity and similarity in signaling events leading to rapid Cox-2 induction by tumor necrosis factor-alpha and phorbol ester in human endothelial cells. Cardiovasc. Res. 65 (2005) 683-693
29. Osuka K., Watanabe Y., Yamauchi K., Nakazawa A., Usuda N., Tokuda M., and Yoshida J. Activation of the JAK-STAT signaling pathz in the rat basilar artery after subarachnoid hemorrhage. Brain Res. 1072 (2006) 1-7
30. Koon H.W., Zhao D., Zhan Y., Rhee S.H., Moyer M.P., and Pothoulakis C. Substance P stimulates cyclooxygenase-2 and prostaglandin E2 expression through JAK-STAT activation in human colonic epithelial cells. J. Immunol. 176 (2006) 5050-5059
31. Tsao P.S., Buitrago R., Chan J.R., and Cooke J.P. Fluid flow inhibits endothelial adhesiveness. Nitric oxide and transcriptional regulation of VCAM-1. Circulation 94 (1996) 1682-1689
32. Garg U.C., and Hassid A. Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J. Clin. Invest. 83 (1989) 1774-1777
33. Chen J.X., Berry Jr. L.C., Christman B.W., Tanner M., Myers P.R., and Meyrick B.O. NO regulates LPS-stimulated cyclooxygenase gene expression and activity in pulmonary artery endothelium. Am. J. Physiol. Lung Cell Mol. Physiol. 280 (2001) L450-L457
34. Forstermann U., and Munzel T. Endothelial nitric oxide synthase in vascular disease: from marvel to menace. Circulation 113 (2006) 1708-1714