Integrated redox sensor and effector functions for tetrahydrobiopterin- and glutathionylation-dependent endothelial nitric-oxide synthase uncoupling

Journal of Biological Chemistry

Volumn 288, Issue 1, 2013, Pages 561-569

  Crabtree, Mark J ^a   Brixey, Rachel ^a   Batchelor, Helen ^a   Hale, Ashley B ^a   Channon, Keith M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COFACTORS; CONCOMITANT REDUCTION; ENDOTHELIAL NITRIC-OXIDE SYNTHASE (ENOS); FUNCTIONAL RELATIONSHIP; GLUTATHIONES; GTP CYCLOHYDROLASE I; NITRIC-OXIDE SYNTHASE; REDOX SENSOR; SUPEROXIDE PRODUCTION; TETRAHYDROBIOPTERIN; VASCULAR HOMEOSTASIS;

COENZYMES; OXYGEN; PEPTIDES;

ENZYME ACTIVITY;

CARMUSTINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE REDUCTASE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; NITRIC OXIDE; SMALL INTERFERING RNA; SUPEROXIDE; TETRAHYDROBIOPTERIN;

ANIMAL CELL; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME REGULATION; GLUTATHIONYLATION; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; OXIDATION; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION;

ANIMALS; ANIONS; BIOPTERIN; CARMUSTINE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE; GLUTATHIONE REDUCTASE; GREEN FLUORESCENT PROTEINS; HUMANS; MICE; MODELS, BIOLOGICAL; MODELS, GENETIC; MUTATION; NIH 3T3 CELLS; NITRIC OXIDE SYNTHASE TYPE III; OXIDATION-REDUCTION; OXYGEN; RNA INTERFERENCE; SUPEROXIDES;

EID: 84872094899     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.415992     Document Type: Article

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