High glucose-induced human umbilical vein endothelial cell hyperpermeability is dependent on protein kinase C activation and independent of the Ca2+-nitric oxide signalling pathway

Clinical and Experimental Pharmacology and Physiology

Volumn 32, Issue 9, 2005, Pages 771-776

  Dang, Lei ^a,b   Seale, J Paul ^b   Qu, Xianqin ^a  

^a UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^b University of Sydney   (Australia)

Author keywords

Ca2+ nitric oxide signalling pathway; Endothelial permeability; High glucose; Histamine; Human umbilical vein endothelial cells; Protein kinase C

Indexed keywords

CALCIUM; FLUORESCENT DYE; FURA 2 ACETOXYMETHYL ESTER; GLUCOSE; HISTAMINE; HYPOCRELLIN A; LY 379196; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; 5,21 - 12,17-DIMETHENEO-18H-DIBENZO(I,O)PYRROLO(3,4-1)(1,8)DIAZACYCLOHEXANDECINE-18,10(19H)DIONE,8((DIMETHYLAMINO)METHYL)-6,7,8,9,10,11-HEXAHYDRO,MONOMETHANESULFONATE; 5,21 12,17 DIMETHENEO 18H DIBENZO(I,O)PYRROLO(3,4 1)(1,8)DIAZACYCLOHEXANDECINE 18,10(19H)DIONE,8((DIMETHYLAMINO)METHYL) 6,7,8,9,10,11 HEXAHYDRO,MONOMETHANESULFONATE; DRUG DERIVATIVE; MESYLIC ACID DERIVATIVE; PERYLENE; PYRROLE DERIVATIVE; QUINONE DERIVATIVE;

ARTICLE; CARDIOVASCULAR DISEASE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DIABETES MELLITUS; DIFFUSION; ENDOTHELIUM CELL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; UMBILICAL VEIN; CALCIUM SIGNALING; CAPILLARY PERMEABILITY; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PERMEABILITY; PHYSIOLOGY;

CALCIUM SIGNALING; CAPILLARY PERMEABILITY; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME ACTIVATION; GLUCOSE; HISTAMINE; HUMANS; MESYLATES; NITRIC OXIDE; OMEGA-N-METHYLARGININE; PERMEABILITY; PERYLENE; PROTEIN KINASE C; PYRROLES; QUINONES;

EID: 26944471223     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2005.04266.x     Document Type: Article

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