메뉴 건너뛰기




Volumn 304, Issue 11, 2013, Pages

CORM-A1 prevents blood-brain barrier dysfunction caused by ionotropic glutamate receptor-mediated endothelial oxidative stress and apoptosis

Author keywords

AMPA; Carbon monoxide; Cerebral vascular endothelium; Glutamate excitotoxicity; Kainite; Mitochondria; NMDA; Vascular injury

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CARBON MONOXIDE; CITRININ; CYTOCHROME C; GLUTAMIC ACID; IONOTROPIC RECEPTOR; IONOTROPIC RECEPTOR AGONIST; KAINIC ACID; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ROTENONE; THENOYLTRIFLUOROACETONE; UBIQUINOL CYTOCHROME C REDUCTASE;

EID: 84878623114     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00023.2013     Document Type: Article
Times cited : (50)

References (46)
  • 1
    • 84855947240 scopus 로고    scopus 로고
    • An improved in vitro blood-brain barrier model: Rat brain endothelial cells co-cultured with astrocytes
    • Abbott NJ, Dolman DE, Drndarski S, Fredriksson SM. An improved in vitro blood-brain barrier model: rat brain endothelial cells co-cultured with astrocytes. Methods Mol Biol 814: 415-430, 2012.
    • (2012) Methods Mol Biol , vol.814 , pp. 415-430
    • Abbott, N.J.1    Dolman, D.E.2    Drndarski, S.3    Fredriksson, S.M.4
  • 2
    • 33751094332 scopus 로고    scopus 로고
    • Heme oxygenase-2 provides endogenous protection against oxidative stress and apoptosis caused by TNFa in cerebral vascular endothelial cells
    • Basuroy S, Bhattacharya S, Tcheranova D, Qu Y, Regan RF, Leffler CW, Parfenova H. Heme oxygenase-2 provides endogenous protection against oxidative stress and apoptosis caused by TNFa in cerebral vascular endothelial cells. Am J Physiol Cell Physiol 291: C897-C908, 2006.
    • (2006) Am J Physiol Cell Physiol , vol.291
    • Basuroy, S.1    Bhattacharya, S.2    Tcheranova, D.3    Qu, Y.4    Regan, R.F.5    Leffler, C.W.6    Parfenova, H.7
  • 3
    • 65249103435 scopus 로고    scopus 로고
    • Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-α in cerebral vascular endothelial cells
    • Basuroy S, Bhattacharya S, Leffler CW, Parfenova H. Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-α in cerebral vascular endothelial cells. Am J Physiol Cell Physiol 296: C422-C432, 2009.
    • (2009) Am J Physiol Cell Physiol , vol.296
    • Basuroy, S.1    Bhattacharya, S.2    Leffler, C.W.3    Parfenova, H.4
  • 4
    • 79251589339 scopus 로고    scopus 로고
    • Nox4 NADPH oxidase-derived reactive oxygen species, via endogenous carbon monoxide, promote survival of brain endothelial cells during TNF-α-induced apoptosis
    • Basuroy S, Tcheranova D, Bhattacharya S, Leffler CW, Parfenova H. Nox4 NADPH oxidase-derived reactive oxygen species, via endogenous carbon monoxide, promote survival of brain endothelial cells during TNF-α-induced apoptosis. Am J Physiol Cell Physiol 300: C256-C265, 2011.
    • (2011) Am J Physiol Cell Physiol , vol.300
    • Basuroy, S.1    Tcheranova, D.2    Bhattacharya, S.3    Leffler, C.W.4    Parfenova, H.5
  • 5
    • 0031762341 scopus 로고    scopus 로고
    • Glutamate in the human brain: Possible role in synaptic transmission and ischemia
    • Berg-Johnsen J, Haugstad TS, Langmoen IA. Glutamate in the human brain: possible role in synaptic transmission and ischemia. Progr Brain Res 116: 287-302, 1998.
    • (1998) Progr Brain Res , vol.116 , pp. 287-302
    • Berg-Johnsen, J.1    Haugstad, T.S.2    Langmoen, I.A.3
  • 7
    • 0034019756 scopus 로고    scopus 로고
    • Glutamate and epilepsy
    • Chapman AG. Glutamate and epilepsy. J Nutr 130: 1043S-1045S, 2000.
    • (2000) J Nutr , vol.130
    • Chapman, A.G.1
  • 8
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate, and neurodegenerative disorders
    • Coyle JT, Puttfarcken P. Oxidative stress, glutamate, and neurodegenerative disorders. Science 262: 689-695, 1993.
    • (1993) Science , vol.262 , pp. 689-695
    • Coyle, J.T.1    Puttfarcken, P.2
  • 9
    • 79551646674 scopus 로고    scopus 로고
    • A dynamic in vitro BBB model for the study of immune cell trafficking into the central nervous system
    • Cucullo L, Marchi N, Hossain M, Janigro D. A dynamic in vitro BBB model for the study of immune cell trafficking into the central nervous system. J Cereb Blood Flow Metab 31: 767-777, 2011.
    • (2011) J Cereb Blood Flow Metab , vol.31 , pp. 767-777
    • Cucullo, L.1    Marchi, N.2    Hossain, M.3    Janigro, D.4
  • 10
    • 35848955210 scopus 로고    scopus 로고
    • Mitochondrial and cellular heme-dependent proteins as targets for the bioactive function of the heme oxygenase/carbon monoxide system
    • Desmard M, Boczkowski J, Poderoso J, Motterlini R. Mitochondrial and cellular heme-dependent proteins as targets for the bioactive function of the heme oxygenase/carbon monoxide system. Antioxid Redox Signal 9: 2139-2155, 2007.
    • (2007) Antioxid Redox Signal , vol.9 , pp. 2139-2155
    • Desmard, M.1    Boczkowski, J.2    Poderoso, J.3    Motterlini, R.4
  • 11
    • 80052266526 scopus 로고    scopus 로고
    • Cross talk between mitochondria and NADPH oxidases
    • Dikalov S. Cross talk between mitochondria and NADPH oxidases. Free Radic Biol Med 51: 1289-1301, 2011.
    • (2011) Free Radic Biol Med , vol.51 , pp. 1289-1301
    • Dikalov, S.1
  • 12
    • 0036213370 scopus 로고    scopus 로고
    • Perinatal brain injury in preterm and term newborn
    • Du Plessis AJ, Volpe JJ. Perinatal brain injury in preterm and term newborn. Curr Opin Neurol 15: 151-157, 2002.
    • (2002) Curr Opin Neurol , vol.15 , pp. 151-157
    • du Plessis, A.J.1    Volpe, J.J.2
  • 13
    • 22744456880 scopus 로고    scopus 로고
    • Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, acti-vators of PPRgamma, and inhibitors of autotaxin
    • Durgam GG, Tsukahara R, Makarova N, Walker MD, Fujiwara Y, Pigg KR, Baker DL, Sardar VM, Parrill AL, Tigyi G, Miller DD. Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, acti-vators of PPRgamma, and inhibitors of autotaxin. J Med Chem 48: 4919-4930, 2005.
    • (2005) J Med Chem , vol.48 , pp. 4919-4930
    • Durgam, G.G.1    Tsukahara, R.2    Makarova, N.3    Walker, M.D.4    Fujiwara, Y.5    Pigg, K.R.6    Baker, D.L.7    Sardar, V.M.8    Parrill, A.L.9    Tigyi, G.10    Miller, D.D.11
  • 14
    • 0037378386 scopus 로고    scopus 로고
    • Carbon monoxide mediates vasodilator effects of glutamate in isolated pressurized cerebral arterioles of newborn pigs
    • Fiumana E, Parfenova H, Jaggar JH, Leffler CW. Carbon monoxide mediates vasodilator effects of glutamate in isolated pressurized cerebral arterioles of newborn pigs. Am J Physiol Heart Circ Physiol 284: H1073-H1079, 2003.
    • (2003) Am J Physiol Heart Circ Physiol , vol.284
    • Fiumana, E.1    Parfenova, H.2    Jaggar, J.H.3    Leffler, C.W.4
  • 15
    • 0028057613 scopus 로고
    • Disruption of epithelial cell-matrix interactions induces apoptosis
    • Frisch SM, Francis H. Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 124: 619-626, 1994.
    • (1994) J Cell Biol , vol.124 , pp. 619-626
    • Frisch, S.M.1    Francis, H.2
  • 16
    • 33645994183 scopus 로고    scopus 로고
    • Calcium, mitochondria and reperfusion injury: A pore way to die
    • Halestrap AP. Calcium, mitochondria and reperfusion injury: a pore way to die. Biochem Soc Trans 34: 232-237, 2006.
    • (2006) Biochem Soc Trans , vol.34 , pp. 232-237
    • Halestrap, A.P.1
  • 17
    • 22944483792 scopus 로고    scopus 로고
    • The blood-brain barrier/neurovascular unit in health and disease
    • Hawkins BT, Davis TP. The blood-brain barrier/neurovascular unit in health and disease. Pharmacol Rev 57: 173-185, 2005.
    • (2005) Pharmacol Rev , vol.57 , pp. 173-185
    • Hawkins, B.T.1    Davis, T.P.2
  • 19
    • 84864309529 scopus 로고    scopus 로고
    • Structure, function, and assembly of heme centers in mitochondrial respiratory complexes
    • Kim HJ, Khalimonchuk O, Smith PM, Winge DR. Structure, function, and assembly of heme centers in mitochondrial respiratory complexes. Biochim Biophys Acta 1823: 1604-1616, 2012.
    • (2012) Biochim Biophys Acta , vol.1823 , pp. 1604-1616
    • Kim, H.J.1    Khalimonchuk, O.2    Smith, P.M.3    Winge, D.R.4
  • 22
    • 0032125488 scopus 로고    scopus 로고
    • Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis
    • Martin LJ, Al-Abdulla NA, Brambrink AM, Kirsch JR, Sieber FE, Portera-Cailliau C. Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis. Brain Res Bull 46: 281-309, 1998.
    • (1998) Brain Res Bull , vol.46 , pp. 281-309
    • Martin, L.J.1    Al-Abdulla, N.A.2    Brambrink, A.M.3    Kirsch, J.R.4    Sieber, F.E.5    Portera-Cailliau, C.6
  • 23
    • 0034065936 scopus 로고    scopus 로고
    • Glutamate as a neurotransmitter in the brain: Review of physiology and pathology
    • Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 130: 1007S-S1015S, 2000.
    • (2000) J Nutr , vol.130
    • Meldrum, B.S.1
  • 26
    • 84857463177 scopus 로고    scopus 로고
    • In vitro blood-brain barrier models: Current and perspective technologies
    • Naik P, Cucullo L. In vitro blood-brain barrier models: Current and perspective technologies. J Pharm Sci 101: 1337-1354, 2012.
    • (2012) J Pharm Sci , vol.101 , pp. 1337-1354
    • Naik, P.1    Cucullo, L.2
  • 28
    • 0036718797 scopus 로고    scopus 로고
    • Beyond the role of glutamate as a neurotransmitter
    • Nedergaard M, Takano T, Hansen AJ. Beyond the role of glutamate as a neurotransmitter. Nat Rev Neurosci 3: 748-755, 2002.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 748-755
    • Nedergaard, M.1    Takano, T.2    Hansen, A.J.3
  • 31
    • 0034796499 scopus 로고    scopus 로고
    • NG2 proteoglycan is expressed exclusively by mural cells during vascular morphogenesis
    • Ozerdem U, Grako KA, Dahlin-Huppe K, Monosov E, Stallcup WB. NG2 proteoglycan is expressed exclusively by mural cells during vascular morphogenesis. Dev Dyn 222: 218-227, 2001.
    • (2001) Dev Dyn , vol.222 , pp. 218-227
    • Ozerdem, U.1    Grako, K.A.2    Dahlin-Huppe, K.3    Monosov, E.4    Stallcup, W.B.5
  • 32
    • 79751525900 scopus 로고    scopus 로고
    • The molecular basis of the blood brain barrier differentiation and maintenance. Is it still a mystery?
    • Paolinelli R, Corada M, Orsenigo F, Dejana E. The molecular basis of the blood brain barrier differentiation and maintenance. Is it still a mystery? Pharmacol Res 63: 165-171, 2011.
    • (2011) Pharmacol Res , vol.63 , pp. 165-171
    • Paolinelli, R.1    Corada, M.2    Orsenigo, F.3    Dejana, E.4
  • 33
    • 33646436473 scopus 로고    scopus 로고
    • Glutamate induces oxidative stress and apoptosis in cerebral vascular endothelial cells: Contributions of HO-1 and HO-2 to cytoprotection
    • Parfenova H, Basuroy S, Bhattacharya S, Tcheranova D, Qu Y, Regan RF, Leffler CW. Glutamate induces oxidative stress and apoptosis in cerebral vascular endothelial cells: contributions of HO-1 and HO-2 to cytoprotection. Am J Physiol Cell Physiol 290: C1399-C1410, 2006.
    • (2006) Am J Physiol Cell Physiol , vol.290
    • Parfenova, H.1    Basuroy, S.2    Bhattacharya, S.3    Tcheranova, D.4    Qu, Y.5    Regan, R.F.6    Leffler, C.W.7
  • 34
    • 0037313972 scopus 로고    scopus 로고
    • Ionotropic glutamate receptors in cerebral microvascular endothelium are functionally linked to heme oxy-genase
    • Parfenova H, Fedinec A, Leffler CW. Ionotropic glutamate receptors in cerebral microvascular endothelium are functionally linked to heme oxy-genase. J Cereb Blood Flow Metab 23: 190-197, 2003.
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 190-197
    • Parfenova, H.1    Fedinec, A.2    Leffler, C.W.3
  • 35
    • 77952619420 scopus 로고    scopus 로고
    • Epileptic seizures increase circulating endothelial cells in peripheral blood as early indicators of cerebral vascular damage
    • Parfenova H, Leffler CW, Tcheranova D, Basuroy S, Zimmermann A. Epileptic seizures increase circulating endothelial cells in peripheral blood as early indicators of cerebral vascular damage. Am J Physiol Heart Circ Physiol 298: H1687-H1698, 2010.
    • (2010) Am J Physiol Heart Circ Physiol , vol.298
    • Parfenova, H.1    Leffler, C.W.2    Tcheranova, D.3    Basuroy, S.4    Zimmermann, A.5
  • 36
    • 84862778861 scopus 로고    scopus 로고
    • Antioxidant roles of heme oxygenase, carbon monoxide, and bilirubin in cerebral circulation during seizures
    • Parfenova H, Leffler CW, Basuroy S, Liu J, Fedinec AL. Antioxidant roles of heme oxygenase, carbon monoxide, and bilirubin in cerebral circulation during seizures. J Cereb Blood Flow Metab 32: 1024-1034, 2012.
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 1024-1034
    • Parfenova, H.1    Leffler, C.W.2    Basuroy, S.3    Liu, J.4    Fedinec, A.L.5
  • 38
    • 8544253949 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress: Cause and consequence of epileptic seizures
    • Patel M. Mitochondrial dysfunction and oxidative stress: cause and consequence of epileptic seizures. Free Radic Biol Med 37: 1951-1962, 2004.
    • (2004) Free Radic Biol Med , vol.37 , pp. 1951-1962
    • Patel, M.1
  • 39
    • 33646019300 scopus 로고    scopus 로고
    • Carbon monoxide, oxidative stress, and mitochondrial permeability pore transition
    • Piantadosi CA, Carrawy MS, Suliman HB. Carbon monoxide, oxidative stress, and mitochondrial permeability pore transition. Free Radic Biol Med 40: 132-139, 2006.
    • (2006) Free Radic Biol Med , vol.40 , pp. 132-139
    • Piantadosi, C.A.1    Carrawy, M.S.2    Suliman, H.B.3
  • 41
    • 0036083293 scopus 로고    scopus 로고
    • Role of carbon monoxide in glutamate receptor-induced dilation of newborn pig pial arterioles
    • Robinson JS, Fedinec AL, Leffler CW. Role of carbon monoxide in glutamate receptor-induced dilation of newborn pig pial arterioles. Am J Physiol Heart Circ Physiol 282: H2371-H2376, 2002.
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Robinson, J.S.1    Fedinec, A.L.2    Leffler, C.W.3
  • 42
    • 4143100246 scopus 로고    scopus 로고
    • L-Glutamine ameliorates acetal-dehyde-induced increase in paracellular permeability in Caco-2 cell mono-layer
    • Seth A, Basuroy S, Sheth P, Rao RK. L-Glutamine ameliorates acetal-dehyde-induced increase in paracellular permeability in Caco-2 cell mono-layer. Am J Physiol Gastrointest Liver Physiol 287: G510-G517, 2004.
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.287
    • Seth, A.1    Basuroy, S.2    Sheth, P.3    Rao, R.K.4
  • 43
    • 72249087964 scopus 로고    scopus 로고
    • Mitochondria, oxidative stress, and temporal lobe epilepsy
    • Waldbaum S, Patel M. Mitochondria, oxidative stress, and temporal lobe epilepsy. Epilepsy Res 88: 23-45, 2010.
    • (2010) Epilepsy Res , vol.88 , pp. 23-45
    • Waldbaum, S.1    Patel, M.2
  • 44
    • 22044453126 scopus 로고    scopus 로고
    • Neonatal seizures: To treat or not to treat?
    • Wirrell EC. Neonatal seizures: to treat or not to treat? Semin Pediatr Neurol 12: 97-105, 2005.
    • (2005) Semin Pediatr Neurol , vol.12 , pp. 97-105
    • Wirrell, E.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.