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Volumn 29, Issue 6, 2010, Pages 553-559

Elevated levels of methylmalonate and homocysteine in Parkinson's disease, progressive supranuclear palsy and amyotrophic lateral sclerosis

Author keywords

Amyotrophic lateral sclerosis; Homocysteine; Levodopa; Methylmalonate; Parkinson's disease; Progressive supranuclear palsy; Vitamin

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; METHYLMALONIC ACID;

EID: 77954189158     PISSN: 14208008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000314841     Document Type: Article
Times cited : (40)

References (40)
  • 1
    • 29044435205 scopus 로고    scopus 로고
    • The diagnosis of Parkinson's disease
    • Tolosa E, Wenning G, Poewe W: The diagnosis of Parkinson's disease. Lancet Neurol 2006; 5: 75-86.
    • (2006) Lancet Neurol , vol.5 , pp. 75-86
    • Tolosa, E.1    Wenning, G.2    Poewe, W.3
  • 2
    • 38949170646 scopus 로고    scopus 로고
    • Unraveling progressive supranuclear palsy: From the bedside back to the bench
    • Houghton DJ, Litvan I: Unraveling progressive supranuclear palsy: from the bedside back to the bench. Parkinsonism Relat Disord 2007; 13(suppl 3):S341-S346.
    • (2007) Parkinsonism Relat Disord , vol.13 , Issue.SUPPL. 3
    • Houghton, D.J.1    Litvan, I.2
  • 3
    • 66149097014 scopus 로고    scopus 로고
    • Incidence and prevalence of amyotrophic lateral sclerosis in Canada: A systematic review of the literature
    • Wolfson C, Kilborn S, Oskoui M, Genge A: Incidence and prevalence of amyotrophic lateral sclerosis in Canada: a systematic review of the literature. Neuroepidemiology 2009; 33: 79-88.
    • (2009) Neuroepidemiology , vol.33 , pp. 79-88
    • Wolfson, C.1    Kilborn, S.2    Oskoui, M.3    Genge, A.4
  • 4
    • 0031597388 scopus 로고    scopus 로고
    • Folate, vitamin B 12 , and serum total homocysteine levels in confirmed Alzheimer disease
    • Clarke R, Smith AD, Jobst KA, Refsum H, Sutton L, Ueland PM: Folate, vitamin B 12 , and serum total homocysteine levels in confirmed Alzheimer disease. Arch Neurol 1998; 55: 1449-1455.
    • (1998) Arch Neurol , vol.55 , pp. 1449-1455
    • Clarke, R.1    Smith, A.D.2    Jobst, K.A.3    Refsum, H.4    Sutton, L.5    Ueland, P.M.6
  • 5
    • 0038387939 scopus 로고    scopus 로고
    • Homocysteine and Alzheimer's disease
    • Morris MS: Homocysteine and Alzheimer's disease. Lancet Neurol 2003; 2: 425-428.
    • (2003) Lancet Neurol , vol.2 , pp. 425-428
    • Morris, M.S.1
  • 7
    • 0028804182 scopus 로고
    • Sulfate and cysteine levels in the plasma of patients with Parkinson's disease
    • Allain P, Le BA, Cordillet E, Le QL, Bagheri H, Montastruc JL: Sulfate and cysteine levels in the plasma of patients with Parkinson's disease. Neurotoxicology 1995; 16: 527-529.
    • (1995) Neurotoxicology , vol.16 , pp. 527-529
    • Allain, P.1    Le Cordillet, E.2    Le Bagheri, H.3    Montastruc, J.L.4
  • 9
    • 23044432096 scopus 로고    scopus 로고
    • Increase of total homocysteine concentration in cerebrospinal fluid in patients with Alzheimer's disease and Parkinson's disease
    • Isobe C, Murata T, Sato C, Terayama Y: Increase of total homocysteine concentration in cerebrospinal fluid in patients with Alzheimer's disease and Parkinson's disease. Life Sci 2005; 77: 1836-1843.
    • (2005) Life Sci , vol.77 , pp. 1836-1843
    • Isobe, C.1    Murata, T.2    Sato, C.3    Terayama, Y.4
  • 11
    • 33745911598 scopus 로고    scopus 로고
    • Vitamins and entacapone in levodopa-induced hyperhomocysteinemia: A randomized controlled study
    • Postuma RB, Espay AJ, Zadikoff C, Suchowersky O, Martin WR, Lafontaine AL, et al: Vitamins and entacapone in levodopa-induced hyperhomocysteinemia: a randomized controlled study. Neurology 2006; 66: 1941-1943.
    • (2006) Neurology , vol.66 , pp. 1941-1943
    • Postuma, R.B.1    Espay, A.J.2    Zadikoff, C.3    Suchowersky, O.4    Martin, W.R.5    Lafontaine, A.L.6
  • 15
    • 33750459018 scopus 로고    scopus 로고
    • Homocysteine serum levels and MTHFR C677T genotype in patients with Parkinson's disease, with and without levodopa therapy
    • Todorovic Z, Dzoljic E, Novakovic I, Mirkovic D, Stojanovic R, Nesic Z, et al: Homocysteine serum levels and MTHFR C677T genotype in patients with Parkinson's disease, with and without levodopa therapy. J Neurol Sci 2006; 248: 56-61.
    • (2006) J Neurol Sci , vol.248 , pp. 56-61
    • Todorovic, Z.1    Dzoljic, E.2    Novakovic, I.3    Mirkovic, D.4    Stojanovic, R.5    Nesic, Z.6
  • 18
    • 1342310863 scopus 로고    scopus 로고
    • Vitamin B 12 status in the elderly as judged by available biochemical markers
    • Obeid R, Schorr H, Eckert R, Herrmann W: Vitamin B 12 status in the elderly as judged by available biochemical markers. Clin Chem 2004; 50: 238-241.
    • (2004) Clin Chem , vol.50 , pp. 238-241
    • Obeid, R.1    Schorr, H.2    Eckert, R.3    Herrmann, W.4
  • 19
    • 17644416088 scopus 로고    scopus 로고
    • Executive dysfunction in hyperhomocystinemia responds to homocysteine- lowering treatment
    • Boxer AL, Kramer JH, Johnston K, Goldman J, Finley R, Miller BL: Executive dysfunction in hyperhomocystinemia responds to homocysteine- lowering treatment. Neurology 2005; 64: 1431-1434.
    • (2005) Neurology , vol.64 , pp. 1431-1434
    • Boxer, A.L.1    Kramer, J.H.2    Johnston, K.3    Goldman, J.4    Finley, R.5    Miller, B.L.6
  • 20
    • 0037188423 scopus 로고    scopus 로고
    • Relationship between plasma homocysteine levels and brain atrophy in healthy elderly individuals
    • Sachdev PS, Valenzuela M, Wang XL, Looi JC, Brodaty H: Relationship between plasma homocysteine levels and brain atrophy in healthy elderly individuals. Neurology 2002; 58: 1539-1541.
    • (2002) Neurology , vol.58 , pp. 1539-1541
    • Sachdev, P.S.1    Valenzuela, M.2    Wang, X.L.3    Looi, J.C.4    Brodaty, H.5
  • 21
    • 33846211794 scopus 로고    scopus 로고
    • Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: A randomised, double blind, controlled trial
    • Durga J, van Boxtel MP, Schouten EG, Kok FJ, Jolles J, Katan MB, et al: Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial. Lancet 2007; 369: 208-216.
    • (2007) Lancet , vol.369 , pp. 208-216
    • Durga, J.1    Van Boxtel, M.P.2    Schouten, E.G.3    Kok, F.J.4    Jolles, J.5    Katan, M.B.6
  • 23
    • 0036270262 scopus 로고    scopus 로고
    • Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease
    • Duan W, Ladenheim B, Cutler RG, Kruman II, Cadet JL, Mattson MP: Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease. J Neurochem 2002; 80: 101-110.
    • (2002) J Neurochem , vol.80 , pp. 101-110
    • Duan, W.1    Ladenheim, B.2    Cutler, R.G.3    Kruman, I.I.4    Cadet, J.L.5    Mattson, M.P.6
  • 24
    • 0041833480 scopus 로고    scopus 로고
    • Folate deprivation induces neurodegeneration: Roles of oxidative stress and increased homocysteine
    • Ho PI, Ashline D, Dhitavat S, Ortiz D, Collins SC, Shea TB, et al: Folate deprivation induces neurodegeneration: roles of oxidative stress and increased homocysteine. Neurobiol Dis 2003; 14: 32-42.
    • (2003) Neurobiol Dis , vol.14 , pp. 32-42
    • Ho, P.I.1    Ashline, D.2    Dhitavat, S.3    Ortiz, D.4    Collins, S.C.5    Shea, T.B.6
  • 26
    • 0037075254 scopus 로고    scopus 로고
    • Homocysteine and dementias
    • Loscalzo J: Homocysteine and dementias. N Engl J Med 2002; 346: 466-468.
    • (2002) N Engl J Med , vol.346 , pp. 466-468
    • Loscalzo, J.1
  • 27
    • 0029803457 scopus 로고    scopus 로고
    • Methylmalonyl-CoA mutase induction by cerebral ischemia and neurotoxicity of the mitochondrial toxin methylmalonic acid
    • Narasimhan P, Sklar R, Murrell M, Swanson RA, Sharp FR: Methylmalonyl-CoA mutase induction by cerebral ischemia and neurotoxicity of the mitochondrial toxin methylmalonic acid. J Neurosci 1996; 16: 7336-7346.
    • (1996) J Neurosci , vol.16 , pp. 7336-7346
    • Narasimhan, P.1    Sklar, R.2    Murrell, M.3    Swanson, R.A.4    Sharp, F.R.5
  • 28
    • 0036523032 scopus 로고    scopus 로고
    • Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease
    • Kruman II, Kumaravel TS, Lohani A, Pedersen WA, Cutler RG, Kruman Y, et al: Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease. J Neurosci 2002; 22: 1752-1762.
    • (2002) J Neurosci , vol.22 , pp. 1752-1762
    • Kruman, I.I.1    Kumaravel, T.S.2    Lohani, A.3    Pedersen, W.A.4    Cutler, R.G.5    Kruman, Y.6
  • 29
    • 58849122658 scopus 로고    scopus 로고
    • Riluzole treatment, survival and diagnostic criteria in Parkinson plus disorders: The NNIPPS study
    • Bensimon G, Ludolph A, Agid Y, Vidailhet M, Payan C, Leigh PN: Riluzole treatment, survival and diagnostic criteria in Parkinson plus disorders: the NNIPPS study. Brain 2009; 132: 156-171.
    • (2009) Brain , vol.132 , pp. 156-171
    • Bensimon, G.1    Ludolph, A.2    Agid, Y.3    Vidailhet, M.4    Payan, C.5    Leigh, P.N.6
  • 30
    • 0027465936 scopus 로고
    • A clinicopathologic study of 100 cases of Parkinson's disease
    • Hughes AJ, Daniel SE, Blankson S, Lees AJ: A clinicopathologic study of 100 cases of Parkinson's disease. Arch Neurol 1993; 50: 140-148.
    • (1993) Arch Neurol , vol.50 , pp. 140-148
    • Hughes, A.J.1    Daniel, S.E.2    Blankson, S.3    Lees, A.J.4
  • 31
    • 34248140690 scopus 로고    scopus 로고
    • External quality assessment of urinary methylmalonic acid quantification - Results of a pilot study
    • Vogeser M, Muller W, Lorenzl S: External quality assessment of urinary methylmalonic acid quantification - results of a pilot study. Clin Chem Lab Med 2007; 45: 695-696.
    • (2007) Clin Chem Lab Med , vol.45 , pp. 695-696
    • Vogeser, M.1    Muller, W.2    Lorenzl, S.3
  • 32
    • 0023262020 scopus 로고
    • Isotope- dilution assay for urinary methylmalonic acid in the diagnosis of vitamin B 12 deficiency. A prospective clinical evaluation
    • Matchar DB, Feussner JR, Millington DS, Wilkinson RH Jr, Watson DJ, Gale D: Isotope- dilution assay for urinary methylmalonic acid in the diagnosis of vitamin B 12 deficiency. A prospective clinical evaluation. Ann Intern Med 1987; 106: 707-710.
    • (1987) Ann Intern Med , vol.106 , pp. 707-710
    • Matchar, D.B.1    Feussner, J.R.2    Millington, D.S.3    Wilkinson Jr., R.H.4    Watson, D.J.5    Gale, D.6
  • 33
    • 0036191376 scopus 로고    scopus 로고
    • Elevated serum methylmalonic acid. How much comes from cobalamin deficiency and how much comes from the kidneys?
    • Lindgren A: Elevated serum methylmalonic acid. How much comes from cobalamin deficiency and how much comes from the kidneys? Scand J Clin Lab Invest 2002; 62: 15-19.
    • (2002) Scand J Clin Lab Invest , vol.62 , pp. 15-19
    • Lindgren, A.1
  • 34
    • 0037225458 scopus 로고    scopus 로고
    • Elevated plasma homocysteine levels in patients treated with levodopa: Association with vascular disease
    • Rogers JD, Sanchez-Saffon A, Frol AB, Diaz- Arrastia R: Elevated plasma homocysteine levels in patients treated with levodopa: association with vascular disease. Arch Neurol 2003; 60: 59-64.
    • (2003) Arch Neurol , vol.60 , pp. 59-64
    • Rogers, J.D.1    Sanchez-Saffon, A.2    Frol, A.B.3    Diaz-Arrastia, R.4
  • 35
    • 33646747001 scopus 로고    scopus 로고
    • Mechanisms of homocysteine neurotoxicity in neurodegenerative diseases with special reference to dementia
    • Obeid R, Herrmann W: Mechanisms of homocysteine neurotoxicity in neurodegenerative diseases with special reference to dementia. FEBS Lett 2006; 580: 2994-3005.
    • (2006) FEBS Lett , vol.580 , pp. 2994-3005
    • Obeid, R.1    Herrmann, W.2
  • 36
    • 0037171072 scopus 로고    scopus 로고
    • Homocysteine induces oxidative cytotoxicity in Cu,Zn-superoxide dismutase mutant motor neuronal cell
    • Sung JJ, Kim HJ, Choi-Kwon S, Lee J, Kim M, Lee KW: Homocysteine induces oxidative cytotoxicity in Cu,Zn-superoxide dismutase mutant motor neuronal cell. Neuroreport 2002; 13: 377-381.
    • (2002) Neuroreport , vol.13 , pp. 377-381
    • Sung, J.J.1    Kim, H.J.2    Choi-Kwon, S.3    Lee, J.4    Kim, M.5    Lee, K.W.6
  • 37
    • 0033882025 scopus 로고    scopus 로고
    • Cobalamin and folate evaluation: Measurement of methylmalonic acid and homocysteine vs vitamin B(12) and folate
    • Klee GG: Cobalamin and folate evaluation: measurement of methylmalonic acid and homocysteine vs vitamin B(12) and folate. Clin Chem 2000; 46: 1277-1283.
    • (2000) Clin Chem , vol.46 , pp. 1277-1283
    • Klee, G.G.1
  • 38
    • 3042647320 scopus 로고    scopus 로고
    • Inhibition of mitochondrial creatine kinase activity from rat cerebral cortex by methylmalonic acid
    • Schuck PF, Rosa RB, Pettenuzzo LF, Sitta A, Wannmacher CM, Wyse AT, et al: Inhibition of mitochondrial creatine kinase activity from rat cerebral cortex by methylmalonic acid. Neurochem Int 2004; 45: 661-667.
    • (2004) Neurochem Int , vol.45 , pp. 661-667
    • Schuck, P.F.1    Rosa, R.B.2    Pettenuzzo, L.F.3    Sitta, A.4    Wannmacher, C.M.5    Wyse, A.T.6
  • 40
    • 0037426415 scopus 로고    scopus 로고
    • Effect of L -dopa on plasma homocysteine in PD patients: Relationship to B-vitamin status
    • Miller JW, Selhub J, Nadeau MR, Thomas CA, Feldman RG, Wolf PA: Effect of L -dopa on plasma homocysteine in PD patients: relationship to B-vitamin status. Neurology 2003; 60: 1125-1129.
    • (2003) Neurology , vol.60 , pp. 1125-1129
    • Miller, J.W.1    Selhub, J.2    Nadeau, M.R.3    Thomas, C.A.4    Feldman, R.G.5    Wolf, P.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.