메뉴 건너뛰기




Volumn 33, Issue 6, 2013, Pages 487-493

Exercise prevents hyperhomocysteinemia in a dietary folate-restricted mouse model

Author keywords

Betaine homocysteine S methyltransferase; BHMT; Exercise; Folate; Hyperhomocysteinemia; Mouse; MS; SAM

Indexed keywords

BETAINE HOMOCYSTEINE METHYLTRANSFERASE; HOMOCYSTEINE;

EID: 84878934031     PISSN: 02715317     EISSN: 18790739     Source Type: Journal    
DOI: 10.1016/j.nutres.2013.04.008     Document Type: Article
Times cited : (26)

References (54)
  • 1
    • 0030979178 scopus 로고    scopus 로고
    • Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage
    • Blount B.C., Mack M.M., Wehr C.M., MacGregor J.T., Hiatt R.A., Wang G., et al. Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage. Proc Natl Acad Sci USA 1997, 94:3290-3295.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3290-3295
    • Blount, B.C.1    Mack, M.M.2    Wehr, C.M.3    MacGregor, J.T.4    Hiatt, R.A.5    Wang, G.6
  • 3
    • 0021143125 scopus 로고
    • Periconceptional vitamin supplementation and the prevention of neural tube defects in south-east England and Northern Ireland
    • Seller M.J., Nevin N.C. Periconceptional vitamin supplementation and the prevention of neural tube defects in south-east England and Northern Ireland. J Med Genet 1984, 21:325-330.
    • (1984) J Med Genet , vol.21 , pp. 325-330
    • Seller, M.J.1    Nevin, N.C.2
  • 4
    • 0037164375 scopus 로고    scopus 로고
    • Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis
    • Wald D.S., Law M., Morris J.K. Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ 2002, 325:1202.
    • (2002) BMJ , vol.325 , pp. 1202
    • Wald, D.S.1    Law, M.2    Morris, J.K.3
  • 6
    • 33846821508 scopus 로고    scopus 로고
    • New insights into the regulation of methyl group and homocysteine metabolism
    • Williams K.T., Schalinske K.L. New insights into the regulation of methyl group and homocysteine metabolism. J Nutr 2007, 137:311-314.
    • (2007) J Nutr , vol.137 , pp. 311-314
    • Williams, K.T.1    Schalinske, K.L.2
  • 7
    • 0034120216 scopus 로고    scopus 로고
    • Training in hypoxia: modulation of metabolic and cardiovascular risk factors in men
    • Bailey D.M., Davies B., Baker J. Training in hypoxia: modulation of metabolic and cardiovascular risk factors in men. Med Sci Sports Exerc 2000, 32:1058-1066.
    • (2000) Med Sci Sports Exerc , vol.32 , pp. 1058-1066
    • Bailey, D.M.1    Davies, B.2    Baker, J.3
  • 9
    • 0035143268 scopus 로고    scopus 로고
    • Nutrient-dense foods and exercise in frail elderly: effects on B vitamins, homocysteine, methylmalonic acid, and neuropsychological functioning
    • de Jong N., Chin A.P.M.J., de Groot L.C., Rutten R.A., Swinkels D.W., Kok F.J., et al. Nutrient-dense foods and exercise in frail elderly: effects on B vitamins, homocysteine, methylmalonic acid, and neuropsychological functioning. Am J Clin Nutr 2001, 73:338-346.
    • (2001) Am J Clin Nutr , vol.73 , pp. 338-346
    • de Jong, N.1    Chin, A.P.M.J.2    de Groot, L.C.3    Rutten, R.A.4    Swinkels, D.W.5    Kok, F.J.6
  • 11
    • 20444450097 scopus 로고    scopus 로고
    • Physical training decreases total plasma homocysteine and cysteine in middle-aged subjects
    • Gaume V., Mougin F., Figard H., Simon-Rigaud M.L., N'Guyen U.N., Callier J., et al. Physical training decreases total plasma homocysteine and cysteine in middle-aged subjects. Ann Nutr Metab 2005, 49:125-131.
    • (2005) Ann Nutr Metab , vol.49 , pp. 125-131
    • Gaume, V.1    Mougin, F.2    Figard, H.3    Simon-Rigaud, M.L.4    N'Guyen, U.N.5    Callier, J.6
  • 13
    • 0038246516 scopus 로고    scopus 로고
    • Influence of training volume and acute physical exercise on the homocysteine levels in endurance-trained men: interactions with plasma folate and vitamin B12
    • Konig D., Bisse E., Deibert P., Muller H.M., Wieland H., Berg A. Influence of training volume and acute physical exercise on the homocysteine levels in endurance-trained men: interactions with plasma folate and vitamin B12. Ann Nutr Metab 2003, 47:114-118.
    • (2003) Ann Nutr Metab , vol.47 , pp. 114-118
    • Konig, D.1    Bisse, E.2    Deibert, P.3    Muller, H.M.4    Wieland, H.5    Berg, A.6
  • 16
    • 4444348988 scopus 로고    scopus 로고
    • Effect of lifestyle factors on plasma total homocysteine concentrations in relation to MTHFR(C677T) genotype. Inter99 (7)
    • Husemoen L.L., Thomsen T.F., Fenger M., Jorgensen T. Effect of lifestyle factors on plasma total homocysteine concentrations in relation to MTHFR(C677T) genotype. Inter99 (7). Eur J Clin Nutr 2004, 58:1142-1150.
    • (2004) Eur J Clin Nutr , vol.58 , pp. 1142-1150
    • Husemoen, L.L.1    Thomsen, T.F.2    Fenger, M.3    Jorgensen, T.4
  • 18
    • 0016366154 scopus 로고
    • Substrate turnover during prolonged exercise in man. Splanchnic and leg metabolism of glucose, free fatty acids, and amino acids
    • Ahlborg G., Felig P., Hagenfeldt L., Hendler R., Wahren J. Substrate turnover during prolonged exercise in man. Splanchnic and leg metabolism of glucose, free fatty acids, and amino acids. J Clin Invest 1974, 53:1080-1090.
    • (1974) J Clin Invest , vol.53 , pp. 1080-1090
    • Ahlborg, G.1    Felig, P.2    Hagenfeldt, L.3    Hendler, R.4    Wahren, J.5
  • 19
    • 0034880489 scopus 로고    scopus 로고
    • BCAA intake affects protein metabolism in muscle after but not during exercise in humans
    • Blomstrand E., Saltin B. BCAA intake affects protein metabolism in muscle after but not during exercise in humans. Am J Physiol Endocrinol Metab 2001, 281:E365-E374.
    • (2001) Am J Physiol Endocrinol Metab , vol.281
    • Blomstrand, E.1    Saltin, B.2
  • 20
    • 0019363571 scopus 로고
    • Influence of exercise on free amino acid concentrations in rat tissues
    • Dohm G.L., Beecher G.R., Warren R.Q., Williams R.T. Influence of exercise on free amino acid concentrations in rat tissues. J Appl Physiol 1981, 50:41-44.
    • (1981) J Appl Physiol , vol.50 , pp. 41-44
    • Dohm, G.L.1    Beecher, G.R.2    Warren, R.Q.3    Williams, R.T.4
  • 21
    • 33744933166 scopus 로고    scopus 로고
    • Carbohydrate metabolism during prolonged exercise and recovery: interactions between pyruvate dehydrogenase, fatty acids, and amino acids
    • Mourtzakis M., Saltin B., Graham T., Pilegaard H. Carbohydrate metabolism during prolonged exercise and recovery: interactions between pyruvate dehydrogenase, fatty acids, and amino acids. J Appl Physiol 2006, 100:1822-1830.
    • (2006) J Appl Physiol , vol.100 , pp. 1822-1830
    • Mourtzakis, M.1    Saltin, B.2    Graham, T.3    Pilegaard, H.4
  • 22
    • 33749461404 scopus 로고    scopus 로고
    • B-vitamins and exercise: does exercise alter requirements?
    • Woolf K., Manore M.M. B-vitamins and exercise: does exercise alter requirements?. Int J Sport Nutr Exerc Metab 2006, 16:453-484.
    • (2006) Int J Sport Nutr Exerc Metab , vol.16 , pp. 453-484
    • Woolf, K.1    Manore, M.M.2
  • 24
    • 8544257376 scopus 로고    scopus 로고
    • Modulation of methyl group metabolism by streptozotocin-induced diabetes and all-trans-retinoic acid
    • Nieman K.M., Rowling M.J., Garrow T.A., Schalinske K.L. Modulation of methyl group metabolism by streptozotocin-induced diabetes and all-trans-retinoic acid. J Biol Chem 2004, 279:45708-45712.
    • (2004) J Biol Chem , vol.279 , pp. 45708-45712
    • Nieman, K.M.1    Rowling, M.J.2    Garrow, T.A.3    Schalinske, K.L.4
  • 25
    • 0242577801 scopus 로고    scopus 로고
    • Retinoic acid and glucocorticoid treatment induce hepatic glycine N-methyltransferase and lower plasma homocysteine concentrations in rats and rat hepatoma cells
    • Rowling M.J., Schalinske K.L. Retinoic acid and glucocorticoid treatment induce hepatic glycine N-methyltransferase and lower plasma homocysteine concentrations in rats and rat hepatoma cells. J Nutr 2003, 133:3392-3398.
    • (2003) J Nutr , vol.133 , pp. 3392-3398
    • Rowling, M.J.1    Schalinske, K.L.2
  • 26
    • 55949123748 scopus 로고    scopus 로고
    • Type 1 diabetes leads to tissue-specific DNA hypomethylation in male rats
    • Williams K.T., Garrow T.A., Schalinske K.L. Type 1 diabetes leads to tissue-specific DNA hypomethylation in male rats. J Nutr 2008, 138:2064-2069.
    • (2008) J Nutr , vol.138 , pp. 2064-2069
    • Williams, K.T.1    Garrow, T.A.2    Schalinske, K.L.3
  • 27
    • 0032906750 scopus 로고    scopus 로고
    • Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirement
    • Bailey L.B., Gregory J.F. Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirement. J Nutr 1999, 129:919-922.
    • (1999) J Nutr , vol.129 , pp. 919-922
    • Bailey, L.B.1    Gregory, J.F.2
  • 28
    • 0036714916 scopus 로고    scopus 로고
    • Hepatic glycine N-methyltransferase is up-regulated by excess dietary methionine in rats
    • Rowling M.J., McMullen M.H., Chipman D.C., Schalinske K.L. Hepatic glycine N-methyltransferase is up-regulated by excess dietary methionine in rats. J Nutr 2002, 132:2545-2550.
    • (2002) J Nutr , vol.132 , pp. 2545-2550
    • Rowling, M.J.1    McMullen, M.H.2    Chipman, D.C.3    Schalinske, K.L.4
  • 29
    • 0025848779 scopus 로고
    • Rapid high-performance liquid chromatographic assay for total homocysteine levels in human serum
    • Ubbink J.B., Hayward Vermaak W.J., Bissbort S. Rapid high-performance liquid chromatographic assay for total homocysteine levels in human serum. J Chromatogr 1991, 565:441-446.
    • (1991) J Chromatogr , vol.565 , pp. 441-446
    • Ubbink, J.B.1    Hayward Vermaak, W.J.2    Bissbort, S.3
  • 30
    • 84856977834 scopus 로고    scopus 로고
    • Tissue-specific alterations of methyl group metabolism with DNA hypermethylation in the Zucker (type 2) diabetic fatty rat
    • Williams K.T., Schalinske K.L. Tissue-specific alterations of methyl group metabolism with DNA hypermethylation in the Zucker (type 2) diabetic fatty rat. Diabetes Metab Res Rev 2012, 28:123-131.
    • (2012) Diabetes Metab Res Rev , vol.28 , pp. 123-131
    • Williams, K.T.1    Schalinske, K.L.2
  • 31
    • 0029787429 scopus 로고    scopus 로고
    • Purification, kinetic properties, and cDNA cloning of mammalian betaine-homocysteine methyltransferase
    • Garrow T.A. Purification, kinetic properties, and cDNA cloning of mammalian betaine-homocysteine methyltransferase. J Biol Chem 1996, 271:22831-22838.
    • (1996) J Biol Chem , vol.271 , pp. 22831-22838
    • Garrow, T.A.1
  • 32
    • 0022004434 scopus 로고
    • Demonstration of methionine synthetase in intestinal mucosal cells of the rat
    • Keating J.N., Weir D.G., Scott J.M. Demonstration of methionine synthetase in intestinal mucosal cells of the rat. Clin Sci (Lond) 1985, 69:287-292.
    • (1985) Clin Sci (Lond) , vol.69 , pp. 287-292
    • Keating, J.N.1    Weir, D.G.2    Scott, J.M.3
  • 34
    • 35848968665 scopus 로고    scopus 로고
    • Physical activity and reduced risk of cardiovascular events: potential mediating mechanisms
    • Mora S., Cook N., Buring J.E., Ridker P.M., Lee I.M. Physical activity and reduced risk of cardiovascular events: potential mediating mechanisms. Circulation 2007, 116:2110-2118.
    • (2007) Circulation , vol.116 , pp. 2110-2118
    • Mora, S.1    Cook, N.2    Buring, J.E.3    Ridker, P.M.4    Lee, I.M.5
  • 36
    • 0035827728 scopus 로고    scopus 로고
    • Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice
    • Dayal S., Bottiglieri T., Arning E., Maeda N., Malinow M.R., Sigmund C.D., et al. Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice. Circ Res 2001, 88:1203-1209.
    • (2001) Circ Res , vol.88 , pp. 1203-1209
    • Dayal, S.1    Bottiglieri, T.2    Arning, E.3    Maeda, N.4    Malinow, M.R.5    Sigmund, C.D.6
  • 37
    • 1542649923 scopus 로고    scopus 로고
    • Effect of mechanical ventilation on carotid artery thrombosis induced by photochemical injury in mice
    • Wilson K.M., Lynch C.M., Faraci F.M., Lentz S.R. Effect of mechanical ventilation on carotid artery thrombosis induced by photochemical injury in mice. J Thromb Haemost 2003, 1:2669-2674.
    • (2003) J Thromb Haemost , vol.1 , pp. 2669-2674
    • Wilson, K.M.1    Lynch, C.M.2    Faraci, F.M.3    Lentz, S.R.4
  • 38
    • 33645796222 scopus 로고    scopus 로고
    • Homocysteine lowering and cardiovascular events after acute myocardial infarction
    • Bonaa K.H., Njolstad I., Ueland P.M., Schirmer H., Tverdal A., Steigen T., et al. Homocysteine lowering and cardiovascular events after acute myocardial infarction. N Engl J Med 2006, 354:1578-1588.
    • (2006) N Engl J Med , vol.354 , pp. 1578-1588
    • Bonaa, K.H.1    Njolstad, I.2    Ueland, P.M.3    Schirmer, H.4    Tverdal, A.5    Steigen, T.6
  • 39
    • 33845964945 scopus 로고    scopus 로고
    • Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: a randomized, placebo-controlled, double-blind trial
    • den Heijer M., Willems H.P., Blom H.J., Gerrits W.B., Cattaneo M., Eichinger S., et al. Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: a randomized, placebo-controlled, double-blind trial. Blood 2007, 109:139-144.
    • (2007) Blood , vol.109 , pp. 139-144
    • den Heijer, M.1    Willems, H.P.2    Blom, H.J.3    Gerrits, W.B.4    Cattaneo, M.5    Eichinger, S.6
  • 40
    • 34548566329 scopus 로고    scopus 로고
    • Effect of homocysteine lowering on mortality and vascular disease in advanced chronic kidney disease and end-stage renal disease: a randomized controlled trial
    • Jamison R.L., Hartigan P., Kaufman J.S., Goldfarb D.S., Warren S.R., Guarino P.D., et al. Effect of homocysteine lowering on mortality and vascular disease in advanced chronic kidney disease and end-stage renal disease: a randomized controlled trial. JAMA 2007, 298:1163-1170.
    • (2007) JAMA , vol.298 , pp. 1163-1170
    • Jamison, R.L.1    Hartigan, P.2    Kaufman, J.S.3    Goldfarb, D.S.4    Warren, S.R.5    Guarino, P.D.6
  • 41
    • 33645753544 scopus 로고    scopus 로고
    • Homocysteine lowering with folic acid and B vitamins in vascular disease
    • Lonn E., Yusuf S., Arnold M.J., Sheridan P., Pogue J., Micks M., et al. Homocysteine lowering with folic acid and B vitamins in vascular disease. N Engl J Med 2006, 354:1567-1577.
    • (2006) N Engl J Med , vol.354 , pp. 1567-1577
    • Lonn, E.1    Yusuf, S.2    Arnold, M.J.3    Sheridan, P.4    Pogue, J.5    Micks, M.6
  • 42
    • 36248955119 scopus 로고    scopus 로고
    • Homocysteine, vitamins, and vascular disease prevention
    • McCully K.S. Homocysteine, vitamins, and vascular disease prevention. Am J Clin Nutr 2007, 86:1563S-1568S.
    • (2007) Am J Clin Nutr , vol.86
    • McCully, K.S.1
  • 46
    • 0027515431 scopus 로고
    • Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism
    • Allen R.H., Stabler S.P., Lindenbaum J. Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism. Metabolism 1993, 42:1448-1460.
    • (1993) Metabolism , vol.42 , pp. 1448-1460
    • Allen, R.H.1    Stabler, S.P.2    Lindenbaum, J.3
  • 47
    • 0035450414 scopus 로고    scopus 로고
    • Immunohistochemical detection of betaine-homocysteine S-methyltransferase in human, pig, and rat liver and kidney
    • Delgado-Reyes C.V., Wallig M.A., Garrow T.A. Immunohistochemical detection of betaine-homocysteine S-methyltransferase in human, pig, and rat liver and kidney. Arch Biochem Biophys 2001, 393:184-186.
    • (2001) Arch Biochem Biophys , vol.393 , pp. 184-186
    • Delgado-Reyes, C.V.1    Wallig, M.A.2    Garrow, T.A.3
  • 49
    • 0031737909 scopus 로고    scopus 로고
    • Effects of streptozotocin-induced diabetes and of insulin treatment on homocysteine metabolism in the rat
    • Jacobs R.L., House J.D., Brosnan M.E., Brosnan J.T. Effects of streptozotocin-induced diabetes and of insulin treatment on homocysteine metabolism in the rat. Diabetes 1998, 47:1967-1970.
    • (1998) Diabetes , vol.47 , pp. 1967-1970
    • Jacobs, R.L.1    House, J.D.2    Brosnan, M.E.3    Brosnan, J.T.4
  • 50
    • 0035941350 scopus 로고    scopus 로고
    • Hyperglucagonemia in rats results in decreased plasma homocysteine and increased flux through the transsulfuration pathway in liver
    • Jacobs R.L., Steads L.M., Brosnan M.E., Brosnan J.T. Hyperglucagonemia in rats results in decreased plasma homocysteine and increased flux through the transsulfuration pathway in liver. J Biol Chem 2001, 276:43740-43747.
    • (2001) J Biol Chem , vol.276 , pp. 43740-43747
    • Jacobs, R.L.1    Steads, L.M.2    Brosnan, M.E.3    Brosnan, J.T.4
  • 53
    • 3142729014 scopus 로고    scopus 로고
    • Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine
    • Stipanuk M.H. Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine. Annu Rev Nutr 2004, 24:539-577.
    • (2004) Annu Rev Nutr , vol.24 , pp. 539-577
    • Stipanuk, M.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.