-
1
-
-
53149113005
-
An escort for GPCRs: Implications for regulation of receptor density at the cell surface
-
Achour L, Labbé-Jullié C, Scott MG, and Marullo S (2008) An escort for GPCRs: implications for regulation of receptor density at the cell surface. Trends Pharmacol Sci 29:528-535.
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 528-535
-
-
Achour, L.1
Labbé-Jullié, C.2
Scott, M.G.3
Marullo, S.4
-
3
-
-
77955874300
-
Time-resolved FRET between GPCR ligands reveals oligomers in native tissues
-
Albizu L, Cottet M, Kralikova M, Stoev S, Seyer R, Brabet I, Roux T, Bazin H, Bourrier E, and Lamarque L, et al. (2010) Time-resolved FRET between GPCR ligands reveals oligomers in native tissues. Nat Chem Biol 6:587-594.
-
(2010)
Nat Chem Biol
, vol.6
, pp. 587-594
-
-
Albizu, L.1
Cottet, M.2
Kralikova, M.3
Stoev, S.4
Seyer, R.5
Brabet, I.6
Roux, T.7
Bazin, H.8
Bourrier, E.9
Lamarque, L.10
-
4
-
-
84874630375
-
PAR-1 contributes to the innate immune response during viral infection
-
Antoniak S, Owens AP 3rd, Baunacke M, Williams JC, Lee RD, Weithäuser A, Sheridan PA, Malz R, Luyendyk JP, and Esserman DA, et al. (2013) PAR-1 contributes to the innate immune response during viral infection. J Clin Invest 123: 1310-1322.
-
(2013)
J Clin Invest
, vol.123
, pp. 1310-1322
-
-
Antoniak, S.1
Owens III, A.P.2
Baunacke, M.3
Williams, J.C.4
Lee, R.D.5
Weithäuser, A.6
Sheridan, P.A.7
Malz, R.8
Luyendyk, J.P.9
Esserman, D.A.10
-
5
-
-
84873557748
-
Calcium mobilization and protein kinase C activation downstream of protease activated receptor 4 (PAR4) is negatively regulated by PAR3 in mouse platelets
-
Arachiche A, de la Fuente M, and Nieman MT (2013) Calcium mobilization and protein kinase C activation downstream of protease activated receptor 4 (PAR4) is negatively regulated by PAR3 in mouse platelets. PLoS ONE 8:e55740.
-
(2013)
PLoS ONE
, vol.8
-
-
Arachiche, A.1
de la Fuente, M.2
Nieman, M.T.3
-
6
-
-
34247388037
-
Protease-activated receptor signalling, endocytic sorting and dysregulation in cancer
-
Arora P, Ricks TK, and Trejo J (2007) Protease-activated receptor signalling, endocytic sorting and dysregulation in cancer. J Cell Sci 120:921-928.
-
(2007)
J Cell Sci
, vol.120
, pp. 921-928
-
-
Arora, P.1
Ricks, T.K.2
Trejo, J.3
-
7
-
-
84872461768
-
Matrix metalloproteases and PAR1 activation
-
Austin KM, Covic L, and Kuliopulos A (2013) Matrix metalloproteases and PAR1 activation. Blood 121:431-439.
-
(2013)
Blood
, vol.121
, pp. 431-439
-
-
Austin, K.M.1
Covic, L.2
Kuliopulos, A.3
-
8
-
-
0037077208
-
Monitoring of ligand-independent dimerization and ligandinduced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer
-
Ayoub MA, Couturier C, Lucas-Meunier E, Angers S, Fossier P, Bouvier M, and Jockers R (2002) Monitoring of ligand-independent dimerization and ligandinduced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer. J Biol Chem 277:21522-21528.
-
(2002)
J Biol Chem
, vol.277
, pp. 21522-21528
-
-
Ayoub, M.A.1
Couturier, C.2
Lucas-Meunier, E.3
Angers, S.4
Fossier, P.5
Bouvier, M.6
Jockers, R.7
-
9
-
-
34547466613
-
Crystal structures of murine thrombin in complex with the extracellular fragments of murine protease-activated receptors PAR3 and PAR4
-
Bah A, Chen Z, Bush-Pelc LA, Mathews FS, and Di Cera E (2007) Crystal structures of murine thrombin in complex with the extracellular fragments of murine protease-activated receptors PAR3 and PAR4. Proc Natl Acad Sci USA 104: 11603-11608.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 11603-11608
-
-
Bah, A.1
Chen, Z.2
Bush-Pelc, L.A.3
Mathews, F.S.4
Di Cera, E.5
-
10
-
-
78651390998
-
Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding
-
Bayburt TH, Vishnivetskiy SA, McLean MA, Morizumi T, Huang CC, Tesmer JJ, Ernst OP, Sligar SG, and Gurevich VV (2011) Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding. J Biol Chem 286:1420-1428.
-
(2011)
J Biol Chem
, vol.286
, pp. 1420-1428
-
-
Bayburt, T.H.1
Vishnivetskiy, S.A.2
McLean, M.A.3
Morizumi, T.4
Huang, C.C.5
Tesmer, J.J.6
Ernst, O.P.7
Sligar, S.G.8
Gurevich, V.V.9
-
11
-
-
0029952336
-
Ligand cross-reactivity within the protease-activated receptor family
-
Blackhart BD, Emilsson K, Nguyen D, Teng W, Martelli AJ, Nystedt S, Sundelin J, and Scarborough RM (1996) Ligand cross-reactivity within the protease-activated receptor family. J Biol Chem 271:16466-16471.
-
(1996)
J Biol Chem
, vol.271
, pp. 16466-16471
-
-
Blackhart, B.D.1
Emilsson, K.2
Nguyen, D.3
Teng, W.4
Martelli, A.J.5
Nystedt, S.6
Sundelin, J.7
Scarborough, R.M.8
-
12
-
-
0035318509
-
Oligomerization of G-protein-coupled transmitter receptors
-
Bouvier M (2001) Oligomerization of G-protein-coupled transmitter receptors. Nat Rev Neurosci 2:274-286.
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 274-286
-
-
Bouvier, M.1
-
13
-
-
74049143122
-
Local protease signaling contributes to neural tube closure in the mouse embryo
-
Camerer E, Barker A, Duong DN, Ganesan R, Kataoka H, Cornelissen I, Darragh MR, Hussain A, Zheng YW, and Srinivasan Y, et al. (2010) Local protease signaling contributes to neural tube closure in the mouse embryo. Dev Cell 18:25-38.
-
(2010)
Dev Cell
, vol.18
, pp. 25-38
-
-
Camerer, E.1
Barker, A.2
Duong, D.N.3
Ganesan, R.4
Kataoka, H.5
Cornelissen, I.6
Darragh, M.R.7
Hussain, A.8
Zheng, Y.W.9
Srinivasan, Y.10
-
14
-
-
0942265965
-
Homodimerization of adenosine A2A receptors: Qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer
-
Canals M, Burgueño J, Marcellino D, Cabello N, Canela EI, Mallol J, Agnati L, Ferré S, Bouvier M, and Fuxe K, et al. (2004) Homodimerization of adenosine A2A receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer. J Neurochem 88:726-734.
-
(2004)
J Neurochem
, vol.88
, pp. 726-734
-
-
Canals, M.1
Burgueño, J.2
Marcellino, D.3
Cabello, N.4
Canela, E.I.5
Mallol, J.6
Agnati, L.7
Ferré, S.8
Bouvier, M.9
Fuxe, K.10
-
15
-
-
0344875553
-
Adenosine A2A-dopamine D2 receptor-receptor heteromerization: Qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer
-
Canals M, Marcellino D, Fanelli F, Ciruela F, de Benedetti P, Goldberg SR, Neve K, Fuxe K, Agnati LF, and Woods AS, et al. (2003) Adenosine A2A-dopamine D2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer. J Biol Chem 278:46741-46749.
-
(2003)
J Biol Chem
, vol.278
, pp. 46741-46749
-
-
Canals, M.1
Marcellino, D.2
Fanelli, F.3
Ciruela, F.4
de Benedetti, P.5
Goldberg, S.R.6
Neve, K.7
Fuxe, K.8
Agnati, L.F.9
Woods, A.S.10
-
16
-
-
81755171483
-
Adaptor protein complex-2 (AP-2) and epsin-1 mediate protease-activated receptor-1 internalization via phosphorylation-and ubiquitination-dependent sorting signals
-
Chen B, Dores MR, Grimsey N, Canto I, Barker BL, and Trejo J (2011) Adaptor protein complex-2 (AP-2) and epsin-1 mediate protease-activated receptor-1 internalization via phosphorylation-and ubiquitination-dependent sorting signals. J Biol Chem 286:40760-40770.
-
(2011)
J Biol Chem
, vol.286
, pp. 40760-40770
-
-
Chen, B.1
Dores, M.R.2
Grimsey, N.3
Canto, I.4
Barker, B.L.5
Trejo, J.6
-
17
-
-
1642368761
-
Termination of protease-activated receptor-1 signaling by b-arrestins is independent of receptor phosphorylation
-
Chen CH, Paing MM, and Trejo J (2004) Termination of protease-activated receptor-1 signaling by b-arrestins is independent of receptor phosphorylation. J Biol Chem 279:10020-10031.
-
(2004)
J Biol Chem
, vol.279
, pp. 10020-10031
-
-
Chen, C.H.1
Paing, M.M.2
Trejo, J.3
-
18
-
-
0028364862
-
Thrombin receptor activation. Confirmation of the intramolecular tethered liganding hypothesis and discovery of an alternative intermolecular liganding mode
-
Chen J, Ishii M, Wang L, Ishii K, and Coughlin SR (1994) Thrombin receptor activation. Confirmation of the intramolecular tethered liganding hypothesis and discovery of an alternative intermolecular liganding mode. J Biol Chem 269: 16041-16045.
-
(1994)
J Biol Chem
, vol.269
, pp. 16041-16045
-
-
Chen, J.1
Ishii, M.2
Wang, L.3
Ishii, K.4
Coughlin, S.R.5
-
19
-
-
0028031081
-
Protease-activated receptors start a family
-
Coughlin SR (1994) Protease-activated receptors start a family. Proc Natl Acad Sci USA 91:9200-9202.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9200-9202
-
-
Coughlin, S.R.1
-
20
-
-
0033613183
-
How the protease thrombin talks to cells
-
Coughlin SR (1999) How the protease thrombin talks to cells. Proc Natl Acad Sci USA 96:11023-11027.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 11023-11027
-
-
Coughlin, S.R.1
-
21
-
-
28344436780
-
Protease-activated receptors in hemostasis, thrombosis and vascular biology
-
Coughlin SR (2005) Protease-activated receptors in hemostasis, thrombosis and vascular biology. J Thromb Haemost 3:1800-1814.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 1800-1814
-
-
Coughlin, S.R.1
-
22
-
-
38549167408
-
Subcellular imaging of dynamic protein interactions by bioluminescence resonance energy transfer
-
Coulon V, Audet M, Homburger V, Bockaert J, Fagni L, Bouvier M, and Perroy J (2008) Subcellular imaging of dynamic protein interactions by bioluminescence resonance energy transfer. Biophys J 94:1001-1009.
-
(2008)
Biophys J
, vol.94
, pp. 1001-1009
-
-
Coulon, V.1
Audet, M.2
Homburger, V.3
Bockaert, J.4
Fagni, L.5
Bouvier, M.6
Perroy, J.7
-
23
-
-
0034625055
-
Biphasic kinetics of activation and signaling for PAR1 and PAR4 thrombin receptors in platelets
-
Covic L, Gresser AL, and Kuliopulos A (2000) Biphasic kinetics of activation and signaling for PAR1 and PAR4 thrombin receptors in platelets. Biochemistry 39: 5458-5467.
-
(2000)
Biochemistry
, vol.39
, pp. 5458-5467
-
-
Covic, L.1
Gresser, A.L.2
Kuliopulos, A.3
-
24
-
-
84860857401
-
Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4)
-
Cunningham MR, McIntosh KA, Pediani JD, Robben J, Cooke AE, Nilsson M, Gould GW, Mundell S, Milligan G, and Plevin R (2012) Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4). J Biol Chem 287:16656-16669.
-
(2012)
J Biol Chem
, vol.287
, pp. 16656-16669
-
-
Cunningham, M.R.1
McIntosh, K.A.2
Pediani, J.D.3
Robben, J.4
Cooke, A.E.5
Nilsson, M.6
Gould, G.W.7
Mundell, S.8
Milligan, G.9
Plevin, R.10
-
25
-
-
84858986564
-
Mapping human protease-activated receptor 4 (PAR4) homodimer interface to transmembrane helix 4
-
de la Fuente M, Noble DN, Verma S, and Nieman MT (2012) Mapping human protease-activated receptor 4 (PAR4) homodimer interface to transmembrane helix 4. J Biol Chem 287:10414-10423.
-
(2012)
J Biol Chem
, vol.287
, pp. 10414-10423
-
-
de la Fuente, M.1
Noble, D.N.2
Verma, S.3
Nieman, M.T.4
-
26
-
-
0034689003
-
β-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2
-
De Fea KA, Zalevsky J, Thoma MS, Déry O, Mullins RD, and Bunnett NW (2000) b-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2. J Cell Biol 148:1267-1281.
-
(2000)
J Cell Biol
, vol.148
, pp. 1267-1281
-
-
De Fea, K.A.1
Zalevsky, J.2
Thoma, M.S.3
Déry, O.4
Mullins, R.D.5
Bunnett, N.W.6
-
27
-
-
61449236177
-
Analysis of receptor oligomerization by FRAP microscopy
-
Dorsch S, Klotz KN, Engelhardt S, Lohse MJ, and Bünemann M (2009) Analysis of receptor oligomerization by FRAP microscopy. Nat Methods 6:225-230.
-
(2009)
Nat Methods
, vol.6
, pp. 225-230
-
-
Dorsch, S.1
Klotz, K.N.2
Engelhardt, S.3
Lohse, M.J.4
Bünemann, M.5
-
28
-
-
84873044382
-
Bimolecular fluorescence complementation analysis of G protein-coupled receptor dimerization in living cells
-
Ejendal KF, Conley JM, Hu CD, and Watts VJ (2013) Bimolecular fluorescence complementation analysis of G protein-coupled receptor dimerization in living cells. Methods Enzymol 521:259-279.
-
(2013)
Methods Enzymol
, vol.521
, pp. 259-279
-
-
Ejendal, K.F.1
Conley, J.M.2
Hu, C.D.3
Watts, V.J.4
-
29
-
-
29244436695
-
Protease-activated receptors-1 and-2 can mediate endothelial barrier protection: Role in factor Xa signaling
-
Feistritzer C, Lenta R, and Riewald M (2005) Protease-activated receptors-1 and-2 can mediate endothelial barrier protection: role in factor Xa signaling. J Thromb Haemost 3:2798-2805.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 2798-2805
-
-
Feistritzer, C.1
Lenta, R.2
Riewald, M.3
-
30
-
-
66849132354
-
Instability of a class a G protein-coupled receptor oligomer interface
-
Fonseca JM and Lambert NA (2009) Instability of a class a G protein-coupled receptor oligomer interface. Mol Pharmacol 75:1296-1299.
-
(2009)
Mol Pharmacol
, vol.75
, pp. 1296-1299
-
-
Fonseca, J.M.1
Lambert, N.A.2
-
31
-
-
0035979691
-
A role for thrombin receptor signaling in endothelial cells during embryonic development
-
Griffin CT, Srinivasan Y, Zheng Y-W, Huang W, and Coughlin SR (2001) A role for thrombin receptor signaling in endothelial cells during embryonic development. Science 293:1666-1670.
-
(2001)
Science
, vol.293
, pp. 1666-1670
-
-
Griffin, C.T.1
Srinivasan, Y.2
Zheng, Y.-W.3
Huang, W.4
Coughlin, S.R.5
-
32
-
-
44449087996
-
Monitoring proteinprotein interactions in living cells by bioluminescence resonance energy transfer (BRET)
-
Unit 5.23
-
Hamdan FF, Percherancier Y, Breton B, and Bouvier M (2006) Monitoring proteinprotein interactions in living cells by bioluminescence resonance energy transfer (BRET). Curr Protoc Neurosci Chapter 5:Unit 5.23.
-
(2006)
Curr Protoc Neurosci Chapter 5
-
-
Hamdan, F.F.1
Percherancier, Y.2
Breton, B.3
Bouvier, M.4
-
33
-
-
33748745670
-
PAR4, but not PAR1, signals human platelet aggregation via Ca2+ mobilization and synergistic P2Y12 receptor activation
-
Holinstat M, Voss B, Bilodeau ML, McLaughlin JN, Cleator J, and Hamm HE (2006) PAR4, but not PAR1, signals human platelet aggregation via Ca2+ mobilization and synergistic P2Y12 receptor activation. J Biol Chem 281:26665-26674.
-
(2006)
J Biol Chem
, vol.281
, pp. 26665-26674
-
-
Holinstat, M.1
Voss, B.2
Bilodeau, M.L.3
McLaughlin, J.N.4
Cleator, J.5
Hamm, H.E.6
-
34
-
-
0037426726
-
The pathophysiology and treatment of sepsis
-
Hotchkiss RS and Karl IE (2003) The pathophysiology and treatment of sepsis. N Engl J Med 348:138-150.
-
(2003)
N Engl J Med
, vol.348
, pp. 138-150
-
-
Hotchkiss, R.S.1
Karl, I.E.2
-
35
-
-
84876197291
-
Crystal structure of oligomeric b1-adrenergic G protein-coupled receptors in ligand-free basal state
-
Huang J, Chen S, Zhang JJ, and Huang XY (2013) Crystal structure of oligomeric b1-adrenergic G protein-coupled receptors in ligand-free basal state. Nat Struct Mol Biol 20:419-425.
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 419-425
-
-
Huang, J.1
Chen, S.2
Zhang, J.J.3
Huang, X.Y.4
-
36
-
-
0030979972
-
Protease-activated receptor 3 is a second thrombin receptor in humans
-
Ishihara H, Connolly AJ, Zeng D, Kahn ML, Zheng YW, Timmons C, Tram T, and Coughlin SR (1997) Protease-activated receptor 3 is a second thrombin receptor in humans. Nature 386:502-506.
-
(1997)
Nature
, vol.386
, pp. 502-506
-
-
Ishihara, H.1
Connolly, A.J.2
Zeng, D.3
Kahn, M.L.4
Zheng, Y.W.5
Timmons, C.6
Tram, T.7
Coughlin, S.R.8
-
37
-
-
0032101592
-
Antibodies to protease-activated receptor 3 inhibit activation of mouse platelets by thrombin
-
Ishihara H, Zeng D, Connolly AJ, Tam C, and Coughlin SR (1998) Antibodies to protease-activated receptor 3 inhibit activation of mouse platelets by thrombin. Blood 91:4152-4157.
-
(1998)
Blood
, vol.91
, pp. 4152-4157
-
-
Ishihara, H.1
Zeng, D.2
Connolly, A.J.3
Tam, C.4
Coughlin, S.R.5
-
38
-
-
0344925961
-
Protease-activated receptor-4 uses dual prolines and an anionic retention motif for thrombin recognition and cleavage
-
Jacques SL and Kuliopulos A (2003) Protease-activated receptor-4 uses dual prolines and an anionic retention motif for thrombin recognition and cleavage. Biochem J 376:733-740.
-
(2003)
Biochem J
, vol.376
, pp. 733-740
-
-
Jacques, S.L.1
Kuliopulos, A.2
-
39
-
-
0034731322
-
Substrate-assisted catalysis of the PAR1 thrombin receptor. Enhancement of macromolecular association and cleavage
-
Jacques SL, LeMasurier M, Sheridan PJ, Seeley SK, and Kuliopulos A (2000) Substrate-assisted catalysis of the PAR1 thrombin receptor. Enhancement of macromolecular association and cleavage. J Biol Chem 275:40671-40678.
-
(2000)
J Biol Chem
, vol.275
, pp. 40671-40678
-
-
Jacques, S.L.1
LeMasurier, M.2
Sheridan, P.J.3
Seeley, S.K.4
Kuliopulos, A.5
-
40
-
-
0033559805
-
Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin
-
Kahn ML, Nakanishi-Matsui M, Shapiro MJ, Ishihara H, and Coughlin SR (1999) Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. J Clin Invest 103:879-887.
-
(1999)
J Clin Invest
, vol.103
, pp. 879-887
-
-
Kahn, M.L.1
Nakanishi-Matsui, M.2
Shapiro, M.J.3
Ishihara, H.4
Coughlin, S.R.5
-
41
-
-
0032514474
-
A dual thrombin receptor system for platelet activation
-
Kahn ML, Zheng YW, Huang W, Bigornia V, Zeng D, Moff S, Farese RV Jr, Tam C, and Coughlin SR (1998) A dual thrombin receptor system for platelet activation. Nature 394:690-694.
-
(1998)
Nature
, vol.394
, pp. 690-694
-
-
Kahn, M.L.1
Zheng, Y.W.2
Huang, W.3
Bigornia, V.4
Zeng, D.5
Moff, S.6
Farese Jr., R.V.7
Tam, C.8
Coughlin, S.R.9
-
42
-
-
36249020418
-
'Role reversal' for the receptor PAR1 in sepsis-induced vascular damage
-
Kaneider NC, Leger AJ, Agarwal A, Nguyen N, Perides G, Derian C, Covic L, and Kuliopulos A (2007) 'Role reversal' for the receptor PAR1 in sepsis-induced vascular damage. Nat Immunol 8:1303-1312.
-
(2007)
Nat Immunol
, vol.8
, pp. 1303-1312
-
-
Kaneider, N.C.1
Leger, A.J.2
Agarwal, A.3
Nguyen, N.4
Perides, G.5
Derian, C.6
Covic, L.7
Kuliopulos, A.8
-
43
-
-
38449083544
-
Dual regulation of endothelial junctional permeability
-
Komarova YA, Mehta D, and Malik AB (2007) Dual regulation of endothelial junctional permeability. Sci STKE 2007:re8.
-
(2007)
Sci STKE
, vol.2007
-
-
Komarova, Y.A.1
Mehta, D.2
Malik, A.B.3
-
44
-
-
33645507738
-
Blocking the protease-activated receptor 1-4 heterodimer in platelet-mediated thrombosis
-
Leger AJ, Jacques SL, Badar J, Kaneider NC, Derian CK, Andrade-Gordon P, Covic L, and Kuliopulos A (2006) Blocking the protease-activated receptor 1-4 heterodimer in platelet-mediated thrombosis. Circulation 113:1244-1254.
-
(2006)
Circulation
, vol.113
, pp. 1244-1254
-
-
Leger, A.J.1
Jacques, S.L.2
Badar, J.3
Kaneider, N.C.4
Derian, C.K.5
Andrade-Gordon, P.6
Covic, L.7
Kuliopulos, A.8
-
45
-
-
27744589182
-
A role for proteinase-activated receptor 2 and PKC-epsilon in thrombin-mediated induction of decay-accelerating factor on human endothelial cells
-
Lidington EA, Steinberg R, Kinderlerer AR, Landis RC, Ohba M, Samarel A, Haskard DO, and Mason JC (2005) A role for proteinase-activated receptor 2 and PKC-epsilon in thrombin-mediated induction of decay-accelerating factor on human endothelial cells. Am J Physiol Cell Physiol 289:C1437-C1447.
-
(2005)
Am J Physiol Cell Physiol
, vol.289
-
-
Lidington, E.A.1
Steinberg, R.2
Kinderlerer, A.R.3
Landis, R.C.4
Ohba, M.5
Samarel, A.6
Haskard, D.O.7
Mason, J.C.8
-
46
-
-
84876578107
-
Transactivation of the PAR1-PAR2 heterodimer by thrombin elicits b-arrestin-mediated endosomal signaling
-
Lin H and Trejo J (2013) Transactivation of the PAR1-PAR2 heterodimer by thrombin elicits b-arrestin-mediated endosomal signaling. J Biol Chem 288: 11203-11215.
-
(2013)
J Biol Chem
, vol.288
, pp. 11203-11215
-
-
Lin, H.1
Trejo, J.2
-
47
-
-
84858203893
-
Fluorescence/bioluminescence resonance energy transfer techniques to study G-protein-coupled receptor activation and signaling
-
Lohse MJ, Nuber S, and Hoffmann C (2012) Fluorescence/bioluminescence resonance energy transfer techniques to study G-protein-coupled receptor activation and signaling. Pharmacol Rev 64:299-336.
-
(2012)
Pharmacol Rev
, vol.64
, pp. 299-336
-
-
Lohse, M.J.1
Nuber, S.2
Hoffmann, C.3
-
48
-
-
84862908085
-
Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes
-
Madhusudhan T, Wang H, Straub BK, Gröne E, Zhou Q, Shahzad K, Müller-Krebs S, Schwenger V, Gerlitz B, and Grinnell BW, et al. (2012) Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes. Blood 119: 874-883.
-
(2012)
Blood
, vol.119
, pp. 874-883
-
-
Madhusudhan, T.1
Wang, H.2
Straub, B.K.3
Gröne, E.4
Zhou, Q.5
Shahzad, K.6
Müller-Krebs, S.7
Schwenger, V.8
Gerlitz, B.9
Grinnell, B.W.10
-
49
-
-
84861096654
-
Crystal structure of the m-opioid receptor bound to a morphinan antagonist
-
Manglik A, Kruse AC, Kobilka TS, Thian FS, Mathiesen JM, Sunahara RK, Pardo L, Weis WI, Kobilka BK, and Granier S (2012) Crystal structure of the m-opioid receptor bound to a morphinan antagonist. Nature 485:321-326.
-
(2012)
Nature
, vol.485
, pp. 321-326
-
-
Manglik, A.1
Kruse, A.C.2
Kobilka, T.S.3
Thian, F.S.4
Mathiesen, J.M.5
Sunahara, R.K.6
Pardo, L.7
Weis, W.I.8
Kobilka, B.K.9
Granier, S.10
-
50
-
-
44449096254
-
Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: Application to GPCR oligomerization
-
Maurel D, Comps-Agrar L, Brock C, Rives ML, Bourrier E, Ayoub MA, Bazin H, Tinel N, Durroux T, and Prézeau L, et al. (2008) Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization. Nat Methods 5:561-567.
-
(2008)
Nat Methods
, vol.5
, pp. 561-567
-
-
Maurel, D.1
Comps-Agrar, L.2
Brock, C.3
Rives, M.L.4
Bourrier, E.5
Ayoub, M.A.6
Bazin, H.7
Tinel, N.8
Durroux, T.9
Prézeau, L.10
-
51
-
-
34248374907
-
Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization
-
McLaughlin JN, Patterson MM, and Malik AB (2007) Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization. Proc Natl Acad Sci USA 104:5662-5667.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 5662-5667
-
-
McLaughlin, J.N.1
Patterson, M.M.2
Malik, A.B.3
-
52
-
-
0345708272
-
G13 is an essential mediator of platelet activation in hemostasis and thrombosis
-
Moers A, Nieswandt B, Massberg S, Wettschureck N, Grüner S, Konrad I, Schulte V, Aktas B, Gratacap MP, and Simon MI, et al. (2003) G13 is an essential mediator of platelet activation in hemostasis and thrombosis. Nat Med 9:1418-1422.
-
(2003)
Nat Med
, vol.9
, pp. 1418-1422
-
-
Moers, A.1
Nieswandt, B.2
Massberg, S.3
Wettschureck, N.4
Grüner, S.5
Konrad, I.6
Schulte, V.7
Aktas, B.8
Gratacap, M.P.9
Simon, M.I.10
-
53
-
-
15444346942
-
Interactions of mast cell tryptase with thrombin receptors and PAR-2
-
Molino M, Barnathan ES, Numerof R, Clark J, Dreyer M, Cumashi A, Hoxie JA, Schechter N, Woolkalis M, and Brass LF (1997) Interactions of mast cell tryptase with thrombin receptors and PAR-2. J Biol Chem 272:4043-4049.
-
(1997)
J Biol Chem
, vol.272
, pp. 4043-4049
-
-
Molino, M.1
Barnathan, E.S.2
Numerof, R.3
Clark, J.4
Dreyer, M.5
Cumashi, A.6
Hoxie, J.A.7
Schechter, N.8
Woolkalis, M.9
Brass, L.F.10
-
54
-
-
84871584695
-
Biased agonism of protease-activated receptor 1 by activated protein C caused by noncanonical cleavage at Arg46
-
Mosnier LO, Sinha RK, Burnier L, Bouwens EA, and Griffin JH (2012) Biased agonism of protease-activated receptor 1 by activated protein C caused by noncanonical cleavage at Arg46. Blood 120:5237-5246.
-
(2012)
Blood
, vol.120
, pp. 5237-5246
-
-
Mosnier, L.O.1
Sinha, R.K.2
Burnier, L.3
Bouwens, E.A.4
Griffin, J.H.5
-
56
-
-
0034611727
-
PAR3 is a cofactor for PAR4 activation by thrombin
-
Nakanishi-Matsui M, Zheng Y-W, Sulciner DJ, Weiss EJ, Ludeman MJ, and Coughlin SR (2000) PAR3 is a cofactor for PAR4 activation by thrombin. Nature 404:609-613.
-
(2000)
Nature
, vol.404
, pp. 609-613
-
-
Nakanishi-Matsui, M.1
Zheng, Y.-W.2
Sulciner, D.J.3
Weiss, E.J.4
Ludeman, M.J.5
Coughlin, S.R.6
-
58
-
-
15844401726
-
The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor
-
Nystedt S, Ramakrishnan V, and Sundelin J (1996) The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor. J Biol Chem 271:14910-14915.
-
(1996)
J Biol Chem
, vol.271
, pp. 14910-14915
-
-
Nystedt, S.1
Ramakrishnan, V.2
Sundelin, J.3
-
59
-
-
0035952643
-
Protease activated receptors: Theme and variations
-
O'Brien PJ, Molino M, Kahn M, and Brass LF (2001) Protease activated receptors: theme and variations. Oncogene 20:1570-1581.
-
(2001)
Oncogene
, vol.20
, pp. 1570-1581
-
-
O'Brien, P.J.1
Molino, M.2
Kahn, M.3
Brass, L.F.4
-
60
-
-
0034608013
-
Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombincleaved PAR1
-
O'Brien PJ, Prevost N, Molino M, Hollinger MK, Woolkalis MJ, Woulfe DS, and Brass LF (2000) Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombincleaved PAR1. J Biol Chem 275:13502-13509.
-
(2000)
J Biol Chem
, vol.275
, pp. 13502-13509
-
-
O'Brien, P.J.1
Prevost, N.2
Molino, M.3
Hollinger, M.K.4
Woolkalis, M.J.5
Woulfe, D.S.6
Brass, L.F.7
-
61
-
-
0030756508
-
Defective platelet activation in G alpha(q)-deficient mice
-
Offermanns S, Toombs CF, Hu YH, and Simon MI (1997) Defective platelet activation in G alpha(q)-deficient mice. Nature 389:183-186.
-
(1997)
Nature
, vol.389
, pp. 183-186
-
-
Offermanns, S.1
Toombs, C.F.2
Hu, Y.H.3
Simon, M.I.4
-
62
-
-
37549016836
-
Heterotrimeric G protein activation by G-proteincoupled receptors
-
Oldham WM and Hamm HE (2008) Heterotrimeric G protein activation by G-proteincoupled receptors. Nat Rev Mol Cell Biol 9:60-71.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 60-71
-
-
Oldham, W.M.1
Hamm, H.E.2
-
63
-
-
33644864081
-
Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization
-
Paing MM, Johnston CA, Siderovski DP, and Trejo J (2006) Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. Mol Cell Biol 26:3231-3242.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3231-3242
-
-
Paing, M.M.1
Johnston, C.A.2
Siderovski, D.P.3
Trejo, J.4
-
64
-
-
15444377047
-
Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in CXCR4 homo-and heterodimers
-
Percherancier Y, Berchiche YA, Slight I, Volkmer-Engert R, Tamamura H, Fujii N, Bouvier M, and Heveker N (2005) Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in CXCR4 homo-and heterodimers. J Biol Chem 280:9895-9903.
-
(2005)
J Biol Chem
, vol.280
, pp. 9895-9903
-
-
Percherancier, Y.1
Berchiche, Y.A.2
Slight, I.3
Volkmer-Engert, R.4
Tamamura, H.5
Fujii, N.6
Bouvier, M.7
Heveker, N.8
-
65
-
-
12344276574
-
Real-time monitoring of ubiquitination in living cells by BRET
-
Perroy J, Pontier S, Charest PG, Aubry M, and Bouvier M (2004) Real-time monitoring of ubiquitination in living cells by BRET. Nat Methods 1:203-208.
-
(2004)
Nat Methods
, vol.1
, pp. 203-208
-
-
Perroy, J.1
Pontier, S.2
Charest, P.G.3
Aubry, M.4
Bouvier, M.5
-
66
-
-
0345803929
-
Heterodimerization of substance P and mu-opioid receptors regulates receptor trafficking and resensitization
-
Pfeiffer M, Kirscht S, Stumm R, Koch T, Wu D, Laugsch M, Schröder H, Höllt V, and Schulz S (2003) Heterodimerization of substance P and mu-opioid receptors regulates receptor trafficking and resensitization. J Biol Chem 278:51630-51637.
-
(2003)
J Biol Chem
, vol.278
, pp. 51630-51637
-
-
Pfeiffer, M.1
Kirscht, S.2
Stumm, R.3
Koch, T.4
Wu, D.5
Laugsch, M.6
Schröder, H.7
Höllt, V.8
Schulz, S.9
-
67
-
-
33747312516
-
Extended bioluminescence resonance energy transfer (eBRET) for monitoring prolonged protein-protein interactions in live cells
-
Pfleger KD, Dromey JR, Dalrymple MB, Lim EM, Thomas WG, and Eidne KA (2006) Extended bioluminescence resonance energy transfer (eBRET) for monitoring prolonged protein-protein interactions in live cells. Cell Signal 18:1664-1670.
-
(2006)
Cell Signal
, vol.18
, pp. 1664-1670
-
-
Pfleger, K.D.1
Dromey, J.R.2
Dalrymple, M.B.3
Lim, E.M.4
Thomas, W.G.5
Eidne, K.A.6
-
68
-
-
0038662595
-
Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors
-
Pin JP, Galvez T, and Prézeau L (2003) Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors. Pharmacol Ther 98:325-354.
-
(2003)
Pharmacol Ther
, vol.98
, pp. 325-354
-
-
Pin, J.P.1
Galvez, T.2
Prézeau, L.3
-
70
-
-
71749108834
-
Phosphorylation of protease-activated receptor-2 differentially regulates desensitization and internalization
-
Ricks TK and Trejo J (2009) Phosphorylation of protease-activated receptor-2 differentially regulates desensitization and internalization. J Biol Chem 284: 34444-34457.
-
(2009)
J Biol Chem
, vol.284
, pp. 34444-34457
-
-
Ricks, T.K.1
Trejo, J.2
-
71
-
-
79551485761
-
Exploring a role for heteromerization in GPCR signalling specificity
-
Rozenfeld R and Devi LA (2011) Exploring a role for heteromerization in GPCR signalling specificity. Biochem J 433:11-18.
-
(2011)
Biochem J
, vol.433
, pp. 11-18
-
-
Rozenfeld, R.1
Devi, L.A.2
-
72
-
-
65549087489
-
Caveolae are required for protease-selective signaling by protease-activated receptor-1
-
Russo A, Soh UJ, Paing MM, Arora P, and Trejo J (2009) Caveolae are required for protease-selective signaling by protease-activated receptor-1. Proc Natl Acad Sci USA 106:6393-6397.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 6393-6397
-
-
Russo, A.1
Soh, U.J.2
Paing, M.M.3
Arora, P.4
Trejo, J.5
-
73
-
-
0025329390
-
The structure of a complex of recombinant hirudin and human alpha-thrombin
-
Rydel TJ, Ravichandran KG, Tulinsky A, Bode W, Huber R, Roitsch C, and Fenton JW 2nd (1990) The structure of a complex of recombinant hirudin and human alpha-thrombin. Science 249:277-280.
-
(1990)
Science
, vol.249
, pp. 277-280
-
-
Rydel, T.J.1
Ravichandran, K.G.2
Tulinsky, A.3
Bode, W.4
Huber, R.5
Roitsch, C.6
Fenton II, J.W.7
-
74
-
-
4043125390
-
Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting
-
Salahpour A, Angers S, Mercier JF, Lagacé M, Marullo S, and Bouvier M (2004) Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting. J Biol Chem 279:33390-33397.
-
(2004)
J Biol Chem
, vol.279
, pp. 33390-33397
-
-
Salahpour, A.1
Angers, S.2
Mercier, J.F.3
Lagacé, M.4
Marullo, S.5
Bouvier, M.6
-
75
-
-
84874363608
-
BRET biosensors to study GPCR biology, pharmacology, and signal transduction
-
Salahpour A, Espinoza S, Masri B, Lam V, Barak LS, and Gainetdinov RR (2012) BRET biosensors to study GPCR biology, pharmacology, and signal transduction. Front Endocrinol (Lausanne) 3:105.
-
(2012)
Front Endocrinol (Lausanne)
, vol.3
, pp. 105
-
-
Salahpour, A.1
Espinoza, S.2
Masri, B.3
Lam, V.4
Barak, L.S.5
Gainetdinov, R.R.6
-
76
-
-
0035817822
-
Role of thrombin signalling in platelets in haemostasis and thrombosis
-
Sambrano GR, Weiss EJ, Zheng YW, Huang W, and Coughlin SR (2001) Role of thrombin signalling in platelets in haemostasis and thrombosis. Nature 413:74-78.
-
(2001)
Nature
, vol.413
, pp. 74-78
-
-
Sambrano, G.R.1
Weiss, E.J.2
Zheng, Y.W.3
Huang, W.4
Coughlin, S.R.5
-
77
-
-
0026629249
-
Tethered ligand agonist peptides. Structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function
-
Scarborough RM, Naughton MA, Teng W, Hung DT, Rose J, Vu TK, Wheaton VI, Turck CW, and Coughlin SR (1992) Tethered ligand agonist peptides. Structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function. J Biol Chem 267:13146-13149.
-
(1992)
J Biol Chem
, vol.267
, pp. 13146-13149
-
-
Scarborough, R.M.1
Naughton, M.A.2
Teng, W.3
Hung, D.T.4
Rose, J.5
Vu, T.K.6
Wheaton, V.I.7
Turck, C.W.8
Coughlin, S.R.9
-
78
-
-
0344668870
-
Structural basis for thrombin activation of a protease-activated receptor: Inhibition of intramolecular liganding
-
Seeley S, Covic L, Jacques SL, Sudmeier J, Baleja JD, and Kuliopulos A (2003) Structural basis for thrombin activation of a protease-activated receptor: inhibition of intramolecular liganding. Chem Biol 10:1033-1041.
-
(2003)
Chem Biol
, vol.10
, pp. 1033-1041
-
-
Seeley, S.1
Covic, L.2
Jacques, S.L.3
Sudmeier, J.4
Baleja, J.D.5
Kuliopulos, A.6
-
79
-
-
79957744641
-
Interdicting protease-activated receptor-2-driven inflammation with cellpenetrating pepducins
-
Sevigny LM, Zhang P, Bohm A, Lazarides K, Perides G, Covic L, and Kuliopulos A (2011) Interdicting protease-activated receptor-2-driven inflammation with cellpenetrating pepducins. Proc Natl Acad Sci USA 108:8491-8496.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 8491-8496
-
-
Sevigny, L.M.1
Zhang, P.2
Bohm, A.3
Lazarides, K.4
Perides, G.5
Covic, L.6
Kuliopulos, A.7
-
80
-
-
0030478939
-
Role of the thrombin receptor's cytoplasmic tail in intracellular trafficking. Distinct determinants for agonisttriggered versus tonic internalization and intracellular localization
-
Shapiro MJ, Trejo J, Zeng D, and Coughlin SR (1996) Role of the thrombin receptor's cytoplasmic tail in intracellular trafficking. Distinct determinants for agonisttriggered versus tonic internalization and intracellular localization. J Biol Chem 271:32874-32880.
-
(1996)
J Biol Chem
, vol.271
, pp. 32874-32880
-
-
Shapiro, M.J.1
Trejo, J.2
Zeng, D.3
Coughlin, S.R.4
-
81
-
-
0034682810
-
Protease-activated receptors 1 and 4 are shut off with distinct kinetics after activation by thrombin
-
Shapiro MJ, Weiss EJ, Faruqi TR, and Coughlin SR (2000) Protease-activated receptors 1 and 4 are shut off with distinct kinetics after activation by thrombin. J Biol Chem 275:25216-25221.
-
(2000)
J Biol Chem
, vol.275
, pp. 25216-25221
-
-
Shapiro, M.J.1
Weiss, E.J.2
Faruqi, T.R.3
Coughlin, S.R.4
-
82
-
-
3543121913
-
Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis
-
Shi X, Gangadharan B, Brass LF, Ruf W, and Mueller BM (2004) Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis. Mol Cancer Res 2:395-402.
-
(2004)
Mol Cancer Res
, vol.2
, pp. 395-402
-
-
Shi, X.1
Gangadharan, B.2
Brass, L.F.3
Ruf, W.4
Mueller, B.M.5
-
83
-
-
77951684623
-
Signal transduction by proteaseactivated receptors
-
Soh UJ, Dores MR, Chen B, and Trejo J (2010) Signal transduction by proteaseactivated receptors. Br J Pharmacol 160:191-203.
-
(2010)
Br J Pharmacol
, vol.160
, pp. 191-203
-
-
Soh, U.J.1
Dores, M.R.2
Chen, B.3
Trejo, J.4
-
84
-
-
84055182505
-
Activated protein C promotes protease-activated receptor-1 cytoprotective signaling through b-arrestin and dishevelled-2 scaffolds
-
Soh UJ and Trejo J (2011) Activated protein C promotes protease-activated receptor-1 cytoprotective signaling through b-arrestin and dishevelled-2 scaffolds. Proc Natl Acad Sci USA 108:E1372-E1380.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
-
-
Soh, U.J.1
Trejo, J.2
-
85
-
-
77953301324
-
N-Linked glycosylation of protease-activated receptor-1 second extracellular loop: A critical determinant for ligand-induced receptor activation and internalization
-
Soto AG and Trejo J (2010) N-Linked glycosylation of protease-activated receptor-1 second extracellular loop: a critical determinant for ligand-induced receptor activation and internalization. J Biol Chem 285:18781-18793.
-
(2010)
J Biol Chem
, vol.285
, pp. 18781-18793
-
-
Soto, A.G.1
Trejo, J.2
-
86
-
-
11244328357
-
Multiple independent functions of arrestins in the regulation of proteaseactivated receptor-2 signaling and trafficking
-
Stalheim L, Ding Y, Gullapalli A, Paing MM, Wolfe BL, Morris DR, and Trejo J (2005) Multiple independent functions of arrestins in the regulation of proteaseactivated receptor-2 signaling and trafficking. Mol Pharmacol 67:78-87.
-
(2005)
Mol Pharmacol
, vol.67
, pp. 78-87
-
-
Stalheim, L.1
Ding, Y.2
Gullapalli, A.3
Paing, M.M.4
Wolfe, B.L.5
Morris, D.R.6
Trejo, J.7
-
87
-
-
0028956090
-
Post-translational and activation-dependent modifications of the G protein-coupled thrombin receptor
-
Vouret-Craviari V, Grall D, Chambard JC, Rasmussen UB, Pouysségur J, and Van Obberghen-Schilling E (1995) Post-translational and activation-dependent modifications of the G protein-coupled thrombin receptor. J Biol Chem 270:8367-8372.
-
(1995)
J Biol Chem
, vol.270
, pp. 8367-8372
-
-
Vouret-Craviari, V.1
Grall, D.2
Chambard, J.C.3
Rasmussen, U.B.4
Pouysségur, J.5
Van Obberghen-Schilling, E.6
-
88
-
-
0026035523
-
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
-
Vu TK, Hung DT, Wheaton VI, and Coughlin SR (1991a) Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64:1057-1068.
-
(1991)
Cell
, vol.64
, pp. 1057-1068
-
-
Vu, T.K.1
Hung, D.T.2
Wheaton, V.I.3
Coughlin, S.R.4
-
89
-
-
0026072517
-
Domains specifying thrombin-receptor interaction
-
Vu TK, Wheaton VI, Hung DT, Charo I, and Coughlin SR (1991b) Domains specifying thrombin-receptor interaction. Nature 353:674-677.
-
(1991)
Nature
, vol.353
, pp. 674-677
-
-
Vu, T.K.1
Wheaton, V.I.2
Hung, D.T.3
Charo, I.4
Coughlin, S.R.5
-
90
-
-
34250666273
-
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
-
Whorton MR, Bokoch MP, Rasmussen SG, Huang B, Zare RN, Kobilka B, and Sunahara RK (2007) A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein. Proc Natl Acad Sci USA 104:7682-7687.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7682-7687
-
-
Whorton, M.R.1
Bokoch, M.P.2
Rasmussen, S.G.3
Huang, B.4
Zare, R.N.5
Kobilka, B.6
Sunahara, R.K.7
-
91
-
-
85027927015
-
Structures of the CXCR4 chemokine GPCR with smallmolecule and cyclic peptide antagonists
-
Wu B, Chien EY, Mol CD, Fenalti G, Liu W, Katritch V, Abagyan R, Brooun A, Wells P, and Bi FC, et al. (2010) Structures of the CXCR4 chemokine GPCR with smallmolecule and cyclic peptide antagonists. Science 330:1066-1071.
-
(2010)
Science
, vol.330
, pp. 1066-1071
-
-
Wu, B.1
Chien, E.Y.2
Mol, C.D.3
Fenalti, G.4
Liu, W.5
Katritch, V.6
Abagyan, R.7
Brooun, A.8
Wells, P.9
Bi, F.C.10
-
92
-
-
84862777742
-
Structure of the human k-opioid receptor in complex with JDTic
-
Wu H, Wacker D, Mileni M, Katritch V, Han GW, Vardy E, Liu W, Thompson AA, Huang XP, and Carroll FI, et al. (2012) Structure of the human k-opioid receptor in complex with JDTic. Nature 485:327-332.
-
(2012)
Nature
, vol.485
, pp. 327-332
-
-
Wu, H.1
Wacker, D.2
Mileni, M.3
Katritch, V.4
Han, G.W.5
Vardy, E.6
Liu, W.7
Thompson, A.A.8
Huang, X.P.9
Carroll, F.I.10
-
93
-
-
0032499696
-
Cloning and characterization of human proteaseactivated receptor 4
-
Xu WF, Andersen H, Whitmore TE, Presnell SR, Yee DP, Ching A, Gilbert T, Davie EW, and Foster DC (1998) Cloning and characterization of human proteaseactivated receptor 4. Proc Natl Acad Sci USA 95:6642-6646.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6642-6646
-
-
Xu, W.F.1
Andersen, H.2
Whitmore, T.E.3
Presnell, S.R.4
Yee, D.P.5
Ching, A.6
Gilbert, T.7
Davie, E.W.8
Foster, D.C.9
-
94
-
-
84871411930
-
High-resolution crystal structure of human protease-activated receptor 1
-
Zhang C, Srinivasan Y, Arlow DH, Fung JJ, Palmer D, Zheng Y, Green HF, Pandey A, Dror RO, and Shaw DE, et al. (2012) High-resolution crystal structure of human protease-activated receptor 1. Nature 492:387-392.
-
(2012)
Nature
, vol.492
, pp. 387-392
-
-
Zhang, C.1
Srinivasan, Y.2
Arlow, D.H.3
Fung, J.J.4
Palmer, D.5
Zheng, Y.6
Green, H.F.7
Pandey, A.8
Dror, R.O.9
Shaw, D.E.10
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