-
1
-
-
0026035523
-
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
-
Vu TK, Hung DT, Wheaton VI, Coughlin SR, (1991) Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64: 1057-1068.
-
(1991)
Cell
, vol.64
, pp. 1057-1068
-
-
Vu, T.K.1
Hung, D.T.2
Wheaton, V.I.3
Coughlin, S.R.4
-
2
-
-
0029143923
-
Mechanisms of thrombin receptor agonist specificity. Chimeric receptors and complementary mutations identify an agonist recognition site
-
Nanevicz T, Ishii M, Wang L, Chen M, Chen J, et al. (1995) Mechanisms of thrombin receptor agonist specificity. Chimeric receptors and complementary mutations identify an agonist recognition site. J Biol Chem 270: 21619-21625.
-
(1995)
J Biol Chem
, vol.270
, pp. 21619-21625
-
-
Nanevicz, T.1
Ishii, M.2
Wang, L.3
Chen, M.4
Chen, J.5
-
3
-
-
0033559805
-
Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin
-
Kahn ML, Nakanishi-Matsui M, Shapiro MJ, Ishihara H, Coughlin SR, (1999) Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. J Clin Invest 103: 879-887.
-
(1999)
J Clin Invest
, vol.103
, pp. 879-887
-
-
Kahn, M.L.1
Nakanishi-Matsui, M.2
Shapiro, M.J.3
Ishihara, H.4
Coughlin, S.R.5
-
4
-
-
0032101592
-
Antibodies to protease-activated receptor 3 inhibit activation of mouse platelets by thrombin
-
Ishihara H, Zeng D, Connolly AJ, Tam C, Coughlin SR, (1998) Antibodies to protease-activated receptor 3 inhibit activation of mouse platelets by thrombin. Blood 91: 4152-4157.
-
(1998)
Blood
, vol.91
, pp. 4152-4157
-
-
Ishihara, H.1
Zeng, D.2
Connolly, A.J.3
Tam, C.4
Coughlin, S.R.5
-
5
-
-
0032514474
-
A dual thrombin receptor system for platelet activation
-
Kahn ML, Zheng YW, Huang W, Bigornia V, Zeng D, et al. (1998) A dual thrombin receptor system for platelet activation. Nature 394: 690-694.
-
(1998)
Nature
, vol.394
, pp. 690-694
-
-
Kahn, M.L.1
Zheng, Y.W.2
Huang, W.3
Bigornia, V.4
Zeng, D.5
-
6
-
-
0034611727
-
PAR3 is a cofactor for PAR4 activation by thrombin
-
Nakanishi-Matsui M, Zheng YW, Sulciner DJ, Weiss EJ, Ludeman MJ, et al. (2000) PAR3 is a cofactor for PAR4 activation by thrombin. Nature 404: 609-613.
-
(2000)
Nature
, vol.404
, pp. 609-613
-
-
Nakanishi-Matsui, M.1
Zheng, Y.W.2
Sulciner, D.J.3
Weiss, E.J.4
Ludeman, M.J.5
-
7
-
-
59749100019
-
RhoA downstream of G(q) and G(12/13) pathways regulates protease-activated receptor-mediated dense granule release in platelets
-
Jin J, Mao Y, Thomas D, Kim S, Daniel JL, et al. (2009) RhoA downstream of G(q) and G(12/13) pathways regulates protease-activated receptor-mediated dense granule release in platelets. Biochem Pharmacol 77: 835-844.
-
(2009)
Biochem Pharmacol
, vol.77
, pp. 835-844
-
-
Jin, J.1
Mao, Y.2
Thomas, D.3
Kim, S.4
Daniel, J.L.5
-
8
-
-
31544455817
-
Relative contribution of G-protein-coupled pathways to protease-activated receptor-mediated Akt phosphorylation in platelets
-
Kim S, Jin J, Kunapuli SP, (2006) Relative contribution of G-protein-coupled pathways to protease-activated receptor-mediated Akt phosphorylation in platelets. Blood 107: 947-954.
-
(2006)
Blood
, vol.107
, pp. 947-954
-
-
Kim, S.1
Jin, J.2
Kunapuli, S.P.3
-
9
-
-
34247545661
-
PAR1, but not PAR4, activates human platelets through a Gi/o/phosphoinositide-3 kinase signaling axis
-
Voss B, McLaughlin JN, Holinstat M, Zent R, Hamm HE, (2007) PAR1, but not PAR4, activates human platelets through a Gi/o/phosphoinositide-3 kinase signaling axis. Mol Pharmacol 71: 1399-1406.
-
(2007)
Mol Pharmacol
, vol.71
, pp. 1399-1406
-
-
Voss, B.1
McLaughlin, J.N.2
Holinstat, M.3
Zent, R.4
Hamm, H.E.5
-
10
-
-
84859103411
-
Protease-activated receptor 1 (PAR1) coupling to G(q/11) but not to G(i/o) or G(12/13) is mediated by discrete amino acids within the receptor second intracellular loop
-
McCoy KL, Gyoneva S, Vellano CP, Smrcka AV, Traynelis SF, et al. (2012) Protease-activated receptor 1 (PAR1) coupling to G(q/11) but not to G(i/o) or G(12/13) is mediated by discrete amino acids within the receptor second intracellular loop. Cell Signal 24: 1351-1360.
-
(2012)
Cell Signal
, vol.24
, pp. 1351-1360
-
-
McCoy, K.L.1
Gyoneva, S.2
Vellano, C.P.3
Smrcka, A.V.4
Traynelis, S.F.5
-
11
-
-
0034897374
-
Impaired activation of murine platelets lacking G alpha(i2)
-
Jantzen HM, Milstone DS, Gousset L, Conley PB, Mortensen RM, (2001) Impaired activation of murine platelets lacking G alpha(i2). J Clin Invest 108: 477-483.
-
(2001)
J Clin Invest
, vol.108
, pp. 477-483
-
-
Jantzen, H.M.1
Milstone, D.S.2
Gousset, L.3
Conley, P.B.4
Mortensen, R.M.5
-
12
-
-
0037092952
-
Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling
-
Kim S, Foster C, Lecchi A, Quinton TM, Prosser DM, et al. (2002) Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling. Blood 99: 3629-3636.
-
(2002)
Blood
, vol.99
, pp. 3629-3636
-
-
Kim, S.1
Foster, C.2
Lecchi, A.3
Quinton, T.M.4
Prosser, D.M.5
-
13
-
-
0036838525
-
Protection against thrombosis in mice lacking PAR3
-
Weiss EJ, Hamilton JR, Lease KE, Coughlin SR, (2002) Protection against thrombosis in mice lacking PAR3. Blood 100: 3240-3244.
-
(2002)
Blood
, vol.100
, pp. 3240-3244
-
-
Weiss, E.J.1
Hamilton, J.R.2
Lease, K.E.3
Coughlin, S.R.4
-
14
-
-
57649115436
-
Protease-activated receptor 4 uses anionic residues to interact with alpha-thrombin in the absence or presence of protease-activated receptor 1
-
Nieman MT, (2008) Protease-activated receptor 4 uses anionic residues to interact with alpha-thrombin in the absence or presence of protease-activated receptor 1. Biochemistry 47: 13279-13286.
-
(2008)
Biochemistry
, vol.47
, pp. 13279-13286
-
-
Nieman, M.T.1
-
15
-
-
33645507738
-
Blocking the protease-activated receptor 1-4 heterodimer in platelet-mediated thrombosis
-
Leger AJ, Jacques SL, Badar J, Kaneider NC, Derian CK, et al. (2006) Blocking the protease-activated receptor 1-4 heterodimer in platelet-mediated thrombosis. Circulation 113: 1244-1254.
-
(2006)
Circulation
, vol.113
, pp. 1244-1254
-
-
Leger, A.J.1
Jacques, S.L.2
Badar, J.3
Kaneider, N.C.4
Derian, C.K.5
-
16
-
-
67651151212
-
Regulation of plasmin-induced protease-activated receptor 4 activation in platelets
-
Mao Y, Jin J, Daniel JL, Kunapuli SP, (2009) Regulation of plasmin-induced protease-activated receptor 4 activation in platelets. Platelets 20: 191-198.
-
(2009)
Platelets
, vol.20
, pp. 191-198
-
-
Mao, Y.1
Jin, J.2
Daniel, J.L.3
Kunapuli, S.P.4
-
17
-
-
34248374907
-
Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization
-
McLaughlin JN, Patterson MM, Malik AB, (2007) Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization. Proc Natl Acad Sci U S A 104: 5662-5667.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 5662-5667
-
-
McLaughlin, J.N.1
Patterson, M.M.2
Malik, A.B.3
-
18
-
-
84862908085
-
Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes
-
Madhusudhan T, Wang H, Straub BK, Grone E, Zhou Q, et al. (2012) Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes. Blood 119: 874-883.
-
(2012)
Blood
, vol.119
, pp. 874-883
-
-
Madhusudhan, T.1
Wang, H.2
Straub, B.K.3
Grone, E.4
Zhou, Q.5
-
19
-
-
40849126406
-
Thrombin generation, fibrin clot formation and hemostasis
-
Wolberg AS, Campbell RA, (2008) Thrombin generation, fibrin clot formation and hemostasis. Transfus Apher Sci 38: 15-23.
-
(2008)
Transfus Apher Sci
, vol.38
, pp. 15-23
-
-
Wolberg, A.S.1
Campbell, R.A.2
-
20
-
-
0021895138
-
A new generation of Ca2+ indicators with greatly improved fluorescence properties
-
Grynkiewicz G, Poenie M, Tsien RY, (1985) A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem 260: 3440-3450.
-
(1985)
J Biol Chem
, vol.260
, pp. 3440-3450
-
-
Grynkiewicz, G.1
Poenie, M.2
Tsien, R.Y.3
-
21
-
-
84858986564
-
Mapping the human protease activated receptor 4 (PAR4) homodimer interface to transmembrane helix 4
-
de la Fuente M, Noble DN, Verma S, Nieman MT, (2012) Mapping the human protease activated receptor 4 (PAR4) homodimer interface to transmembrane helix 4. J Biol Chem 287: 10414-10423.
-
(2012)
J Biol Chem
, vol.287
, pp. 10414-10423
-
-
de la Fuente, M.1
Noble, D.N.2
Verma, S.3
Nieman, M.T.4
-
22
-
-
0031914973
-
Molecular basis for ADP-induced platelet activation. I. Evidence for three distinct ADP receptors on human platelets
-
Daniel JL, Dangelmaier C, Jin J, Ashby B, Smith JB, et al. (1998) Molecular basis for ADP-induced platelet activation. I. Evidence for three distinct ADP receptors on human platelets. J Biol Chem 273: 2024-2029.
-
(1998)
J Biol Chem
, vol.273
, pp. 2024-2029
-
-
Daniel, J.L.1
Dangelmaier, C.2
Jin, J.3
Ashby, B.4
Smith, J.B.5
-
23
-
-
79952783713
-
Arrestin-2 differentially regulates PAR4 and ADP receptor signaling in platelets
-
Li D, D'Angelo L, Chavez M, Woulfe DS, (2011) Arrestin-2 differentially regulates PAR4 and ADP receptor signaling in platelets. J Biol Chem 286: 3805-3814.
-
(2011)
J Biol Chem
, vol.286
, pp. 3805-3814
-
-
Li, D.1
D'Angelo, L.2
Chavez, M.3
Woulfe, D.S.4
-
24
-
-
43549100273
-
GSK3beta is a negative regulator of platelet function and thrombosis
-
Li D, August S, Woulfe DS, (2008) GSK3beta is a negative regulator of platelet function and thrombosis. Blood 111: 3522-3530.
-
(2008)
Blood
, vol.111
, pp. 3522-3530
-
-
Li, D.1
August, S.2
Woulfe, D.S.3
-
25
-
-
80054119619
-
An important role for Akt3 in platelet activation and thrombosis
-
O'Brien KA, Stojanovic-Terpo A, Hay N, Du X, (2011) An important role for Akt3 in platelet activation and thrombosis. Blood 118: 4215-4223.
-
(2011)
Blood
, vol.118
, pp. 4215-4223
-
-
O'Brien, K.A.1
Stojanovic-Terpo, A.2
Hay, N.3
Du, X.4
-
26
-
-
33645820837
-
Differential regulation of platelet aggregation and aminophospholipid exposure by calpain
-
Bachelot-Loza C, Badol P, Brohard-Bohn B, Fraiz N, Cano E, et al. (2006) Differential regulation of platelet aggregation and aminophospholipid exposure by calpain. Br J Haematol 133: 419-426.
-
(2006)
Br J Haematol
, vol.133
, pp. 419-426
-
-
Bachelot-Loza, C.1
Badol, P.2
Brohard-Bohn, B.3
Fraiz, N.4
Cano, E.5
-
27
-
-
73949144549
-
Rapid procoagulant phosphatidylserine exposure relies on high cytosolic calcium rather than on mitochondrial depolarization
-
Arachiche A, Kerbiriou-Nabias D, Garcin I, Letellier T, Dachary-Prigent J, (2009) Rapid procoagulant phosphatidylserine exposure relies on high cytosolic calcium rather than on mitochondrial depolarization. Arterioscler Thromb Vasc Biol 29: 1883-1889.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 1883-1889
-
-
Arachiche, A.1
Kerbiriou-Nabias, D.2
Garcin, I.3
Letellier, T.4
Dachary-Prigent, J.5
-
28
-
-
33846279424
-
Differential involvement of thrombin receptors in Ca2+ release from two different intracellular stores in human platelets
-
Jardin I, Ben Amor N, Bartegi A, Pariente JA, Salido GM, et al. (2007) Differential involvement of thrombin receptors in Ca2+ release from two different intracellular stores in human platelets. Biochem J 401: 167-174.
-
(2007)
Biochem J
, vol.401
, pp. 167-174
-
-
Jardin, I.1
Ben Amor, N.2
Bartegi, A.3
Pariente, J.A.4
Salido, G.M.5
-
29
-
-
80051470601
-
Acidic Ca(2+) stores in platelets
-
Rosado JA, (2011) Acidic Ca(2+) stores in platelets. Cell Calcium 50: 168-174.
-
(2011)
Cell Calcium
, vol.50
, pp. 168-174
-
-
Rosado, J.A.1
-
30
-
-
80051585023
-
PKC inhibition markedly enhances Ca(2+) signalling and phosphatidylserine exposure downstream of protease-activated receptor-1 but not protease-activated receptor-4 in human platelets
-
Harper MT, Poole AW, (2011) PKC inhibition markedly enhances Ca(2+) signalling and phosphatidylserine exposure downstream of protease-activated receptor-1 but not protease-activated receptor-4 in human platelets. J Thromb Haemost 9: 1599-1607.
-
(2011)
J Thromb Haemost
, vol.9
, pp. 1599-1607
-
-
Harper, M.T.1
Poole, A.W.2
-
31
-
-
36249020418
-
Role reversal' for the receptor PAR1 in sepsis-induced vascular damage
-
Kaneider NC, Leger AJ, Agarwal A, Nguyen N, Perides G, et al. (2007) 'Role reversal' for the receptor PAR1 in sepsis-induced vascular damage. Nat Immunol 8: 1303-1312.
-
(2007)
Nat Immunol
, vol.8
, pp. 1303-1312
-
-
Kaneider, N.C.1
Leger, A.J.2
Agarwal, A.3
Nguyen, N.4
Perides, G.5
-
32
-
-
59349092419
-
Determination of supramolecular structure and spatial distribution of protein complexes in living cells
-
Raicu V, Stoneman MR, Fung R, Melnichuk M, Jansma DB, et al. (2009) Determination of supramolecular structure and spatial distribution of protein complexes in living cells. Nature Photonics 3: 107-113.
-
(2009)
Nature Photonics
, vol.3
, pp. 107-113
-
-
Raicu, V.1
Stoneman, M.R.2
Fung, R.3
Melnichuk, M.4
Jansma, D.B.5
-
33
-
-
77952757509
-
Oligomeric size of the m2 muscarinic receptor in live cells as determined by quantitative fluorescence resonance energy transfer
-
Pisterzi LF, Jansma DB, Georgiou J, Woodside MJ, Chou JT, et al. (2010) Oligomeric size of the m2 muscarinic receptor in live cells as determined by quantitative fluorescence resonance energy transfer. J Biol Chem 285: 16723-16738.
-
(2010)
J Biol Chem
, vol.285
, pp. 16723-16738
-
-
Pisterzi, L.F.1
Jansma, D.B.2
Georgiou, J.3
Woodside, M.J.4
Chou, J.T.5
-
34
-
-
36348981019
-
Protease-activated receptor-induced Akt activation-regulation and possible function
-
Resendiz JC, Kroll MH, Lassila R, (2007) Protease-activated receptor-induced Akt activation-regulation and possible function. J Thromb Haemost 5: 2484-2493.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 2484-2493
-
-
Resendiz, J.C.1
Kroll, M.H.2
Lassila, R.3
-
35
-
-
84857520121
-
A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling
-
Ma P, Cierniewska A, Signarvic R, Cieslak M, Kong H, et al. (2012) A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling. Blood 119: 1935-1945.
-
(2012)
Blood
, vol.119
, pp. 1935-1945
-
-
Ma, P.1
Cierniewska, A.2
Signarvic, R.3
Cieslak, M.4
Kong, H.5
-
36
-
-
28844437680
-
Inhibition of serotonin 5-hydroxytryptamine2c receptor function through heterodimerization: receptor dimers bind two molecules of ligand and one G-protein
-
Herrick-Davis K, Grinde E, Harrigan TJ, Mazurkiewicz JE, (2005) Inhibition of serotonin 5-hydroxytryptamine2c receptor function through heterodimerization: receptor dimers bind two molecules of ligand and one G-protein. J Biol Chem 280: 40144-40151.
-
(2005)
J Biol Chem
, vol.280
, pp. 40144-40151
-
-
Herrick-Davis, K.1
Grinde, E.2
Harrigan, T.J.3
Mazurkiewicz, J.E.4
|