Crystal structures of murine thrombin in complex with the extracellular fragments of murine protease-activated receptors PAR3 and PAR4

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 28, 2007, Pages 11603-11608

  Bah, Alaji ^a   Chen, Zhiwei ^a   Bush Pelc, Leslie A ^a   Mathews, F Scott ^a   Di Cera, Enrico ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Allostery; Signal transduction; X ray structure

Indexed keywords

GLYCINE; PROLINE; PROTEINASE ACTIVATED RECEPTOR 3; PROTEINASE ACTIVATED RECEPTOR 4; THROMBIN; TRYPTOPHAN; TYROSINE;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DIFFUSION; ELECTRON TRANSPORT; ENZYME ACTIVE SITE; HYDROPHOBICITY; MOUSE; NONHUMAN; OPTICAL RESOLUTION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; THROMBOCYTE ACTIVATION; THROMBOGENESIS; X RAY ANALYSIS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CELL ADHESION MOLECULES; COENZYMES; CRYSTALLOGRAPHY, X-RAY; EXTRACELLULAR SPACE; HYDROLYSIS; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN BINDING; RECEPTORS, THROMBIN; THROMBIN;

MURINAE;

EID: 34547466613     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0704409104     Document Type: Article

References (54)

1. Di Cera E (2003) Chest 124:11S-17S.
2. Di Cera E, Page MJ, Bah A, Bush-Pelc LA, Garvey LC (2007) Phys Chem Chem Phys 9:1292-1306.
3. Davie EW, Kulman JD (2006) Semin Thromb Hemostasis 32(Suppl 1):3-15.
4. Esmon CT (2003) Chest 124:26S-32S.
5. Brass LF (2003) Chest 124:18S-25S.
6. Coughlin SR (2000) Nature 407:258-264.
7. Vu TK, Wheaton VI, Hung DT, Charo I, Coughlin SR (1991) Nature 353:674-677.
8. Ishihara H, Connolly AJ, Zeng D, Kahn ML, Zheng YW, Timmons C, Tram T, Coughlin SR (1997) Nature 386:502-506.
9. Sambrano GR, Weiss EJ, Zheng YW, Huang W, Coughlin SR (2001) Nature 413:74-78.
10. Kahn ML, Zheng YW, Huang W, Bigornia V, Zeng D, Moff S, Farese RV, Jr, Tam C, Coughlin SR (1998) Nature 394:690-694.
11. Nakanishi-Matsui M, Zheng YW, Sulciner DJ, Weiss EJ, Ludeman MJ, Coughlin SR (2000) Nature 404:609-613.
12. Xu WF, Andersen H, Whitmore TE, Presnell SR, Yee DP, Ching A, Gilbert T, Davie EW, Foster DC (1998) Proc Natl Acad Sci USA 95:6642-6646.
13. Shapiro MJ, Weiss EJ, Faruqi TR, Coughlin SR (2000) J Biol Chem 275:25216-25221.
14. McLaughlin JN, Patterson MM, Malik AB (2007) Proc Natl Acad Sci USA 104:5662-5667.
15. Bode W (2006) Blood Cells Mol Dis 36:122-130.
16. Page MJ, MacGillivray RTA, Di Cera E (2005) J Thromb Haemostasis 3:2401-2408.
17. Fenton JW, II (1986) Ann NY Acad Sci 485:5-15.
18. Ayala Y, Di Cera E (1994) J Mol Biol 235:733-746.
19. Lai MT, Di Cera E, Shafer JA (1997) J Biol Chem 272:30275-30282.
20. Liu LW, Vu TK, Esmon CT, Coughlin SR (1991) J Biol Chem 266:16977-16980.
21. Vindigni A, White CE, Komives EA, Di Cera E (1997) Biochemistry 36:6674-6681.
22. Verhamme IM, Olson ST, Tollefsen DM, Bock PE (2002) J Biol Chem 277:6788-6798.
23. Colwell NS, Blinder MA, Tsiang M, Gibbs CS, Bock PE, Tollefsen DM (1998) Biochemistry 37:15057-15065.
24. Bartunik HD, Summers LJ, Bartsch HH (1989) J Mol Biol 210:813-828.
25. Tsiang M, Jain AK, Dunn KE, Rojas ME, Leung LL, Gibbs CS (1995) J Biol Chem 270:16854-16863.
26. Ayala YM, Cantwell AM, Rose T, Bush LA, Arosio D, Di Cera E (2001) Proteins 45:107-116.
27. Pechik I, Madrazo J, Mosesson MW, Hernandez I, Gilliland GL, Medved L (2004) Proc Natl Acad Sci USA 101:2718-2723.
28. Pechik I, Yakovlev S, Mosesson MW, Gilliland GL, Medved L (2006) Biochemistry 45:3588-3597.
29. Hall SW, Nagashima M, Zhao L, Morser J, Leung LL (1999) J Biol Chem 274:25510-25516.
30. Fuentes-Prior P, Iwanaga Y, Huber R, Pagila R, Rumennik G, Seto M, Morser J, Light DR, Bode W (2000) Nature 404:518-525.
31. Pineda AO, Cantwell AM, Bush LA, Rose T, Di Cera E (2002) J Biol Chem 277:32015-32019.
32. Xu H, Bush LA, Pineda AO, Caccia S, Di Cera E (2005) J Biol Chem 280:7956-7961.
33. Myles T, Le Bonniec BF, Stone SR (2001) Eur J Biochem 268:70-77.
34. Mathews II, Padmanabhan KP, Ganesh V, Tulinsky A, Ishii M, Chen J, Turck CW, Coughlin SR, Fenton JW, II (1994) Biochemistry 33:3266-3279.
35. Rydel TJ, Tulinsky A, Bode W, Huber R (1991) J Mol Biol 221:583-601.
36. Cleary DB, Trumbo TA, Maurer MC (2002) Arch Biochem Biophys 403:179-188.
37. Jacques SL, Kuliopulos A (2003) Biochem J 376:733-740.
38. Seeley S, Covic L, Jacques SL, Sudmeier J, Baleja JD, Kuliopulos A (2003) Chem Biol 10:1033-1041.
39. Marino F, Chen ZW, Ergenekan C, Bush-Pelc LA, Mathews FS, Di Cera E (2007) J Biol Chem 282:16355-16361.
40. Bode W, Turk D, Karshikov A (1992) Protein Sci 1:426-471.
41. Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E (2004) J Biol Chem 279:31842-31853.
42. Vijayalakshmi J, Padmanabhan KP, Mann KG, Tulinsky A (1994) Protein Sci 3:2254-2271.
43. Bah A, Garvey LC, Ge J, Di Cera E (2006) J Biol Chem 281:40049-40056.
44. Hedstrom L (2002) Chem Rev 102:4501-4524.
45. Perona JJ, Craik CS (1995) Protein Sci 4:337-360.
46. Parry MA, Stone SR, Hofsteenge J, Jackman MP (1993) Biochem J 290:665-670.
47. Pineda AO, Chen ZW, Caccia S, Cantwell AM, Sawides SN, Waksman G, Mathews FS, Di Cera E (2004) J Biol Chem 279:39824-39828.
48. van de Locht A, Bode W, Huber R, Le Bonniec BF, Stone SR, Esmon CT, Stubbs MT (1997) EMBO J 16:2977-2984.
49. Malkowski MG, Martin PD, Guzik JC, Edwards BFP (1997) Protein Sci 6:1438-1448.
50. Bush LA, Nelson RW, Di Cera E (2006) J Biol Chem 281:7183-7188.
51. Otwinowski Z, Minor W (1997) Methods Enzymol 276:307-326.
52. Bailey S (1994) Acta Crystallogr D 50:760-763.
53. Brunger AT, Adams PD, Clore GM, DeLano WL, Gros P, Grosse-Kunstleve RW, Jiang JS, Kuszewski J, Nilges M, Pannu NS, et al. (1998) Acta Crystallogr D 54:905-921.
54. Morris AL, MacArthur MW, Hutchinson EG, Thornton JM (1992) Proteins 12:345-364.