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Volumn 111, Issue 1, 2014, Pages 125-133

Construction of a controllable β-carotene biosynthetic pathway by decentralized assembly strategy in Saccharomyces cerevisiae

Author keywords

carotene; Biosynthetic pathway; Decentralized assembly; Functional module; PMRI

Indexed keywords

BIOSYNTHESIS PATHWAYS; BIOSYNTHETIC PATHWAY; FUNCTIONAL MODULES; GENETIC STABILITY; PMRI; PROOF OF PRINCIPLES; REGULATORY SYSTEMS; SHAKE-FLASK CULTURES;

EID: 84888060999     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25002     Document Type: Article
Times cited : (138)

References (50)
  • 1
    • 77951531018 scopus 로고    scopus 로고
    • Enhancement of Farnesyl diphosphate pool as direct precursor of sesquiterpenes through metabolic engineering of the mevalonate pathway in Saccharomyces cerevisiae
    • Asadollahi MA, Maury J, Schalk M, Clark A, Nielsen J. 2010. Enhancement of Farnesyl diphosphate pool as direct precursor of sesquiterpenes through metabolic engineering of the mevalonate pathway in Saccharomyces cerevisiae. Biotechnol Bioeng 106(1):86-96.
    • (2010) Biotechnol Bioeng , vol.106 , Issue.1 , pp. 86-96
    • Asadollahi, M.A.1    Maury, J.2    Schalk, M.3    Clark, A.4    Nielsen, J.5
  • 2
    • 84863634266 scopus 로고    scopus 로고
    • Construction of synthetic regulatory networks in yeast
    • Blount BA, Weenink T, Ellis T. 2012. Construction of synthetic regulatory networks in yeast. FEBS Lett 586(15):2112-2121.
    • (2012) FEBS Lett , vol.586 , Issue.15 , pp. 2112-2121
    • Blount, B.A.1    Weenink, T.2    Ellis, T.3
  • 3
    • 0032579440 scopus 로고    scopus 로고
    • Designer deletion strains derived from Saccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCR-mediated gene disruption and other applications
    • Brachmann CB, Davies A, Cost GJ, Caputo E, Li JC, Hieter P, Boeke JD. 1998. Designer deletion strains derived from Saccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast 14(2):115-132.
    • (1998) Yeast , vol.14 , Issue.2 , pp. 115-132
    • Brachmann, C.B.1    Davies, A.2    Cost, G.J.3    Caputo, E.4    Li, J.C.5    Hieter, P.6    Boeke, J.D.7
  • 4
    • 0028046767 scopus 로고
    • Optimization of the expression system using galactose-inducible promoter for the production of anticoagulant hirudin in Saccharomyces cerevisiae
    • Choi ES, Sohn JH, Rhee SK. 1994. Optimization of the expression system using galactose-inducible promoter for the production of anticoagulant hirudin in Saccharomyces cerevisiae. Appl Microbiol Biotechnol 42(4):587-594.
    • (1994) Appl Microbiol Biotechnol , vol.42 , Issue.4 , pp. 587-594
    • Choi, E.S.1    Sohn, J.H.2    Rhee, S.K.3
  • 5
    • 63649099433 scopus 로고    scopus 로고
    • Reconstruction and logical modeling of glucose repression signaling pathways in Saccharomyces cerevisiae
    • Christensen TS, Oliveira AP, Nielsen J. 2009. Reconstruction and logical modeling of glucose repression signaling pathways in Saccharomyces cerevisiae. BMC Syst Biol 3:7.
    • (2009) BMC Syst Biol , vol.3 , pp. 7
    • Christensen, T.S.1    Oliveira, A.P.2    Nielsen, J.3
  • 6
    • 0024558335 scopus 로고
    • One-step preparation of competent Escherichia coli: Transformation and storage of bacterial cells in the same solution
    • Chung CT, Niemela SL, Miller RH. 1989. One-step preparation of competent Escherichia coli: Transformation and storage of bacterial cells in the same solution. Proc Natl Acad Sci USA 86(7):2172-2175.
    • (1989) Proc Natl Acad Sci USA , vol.86 , Issue.7 , pp. 2172-2175
    • Chung, C.T.1    Niemela, S.L.2    Miller, R.H.3
  • 7
    • 84857053335 scopus 로고    scopus 로고
    • Introduction and expression of genes for metabolic engineering applications in Saccharomyces cerevisiae
    • Da Silva NA, Srikrishnan S. 2012. Introduction and expression of genes for metabolic engineering applications in Saccharomyces cerevisiae. FEMS Yeast Res 12(2):197-214.
    • (2012) FEMS Yeast Res , vol.12 , Issue.2 , pp. 197-214
    • Da Silva, N.A.1    Srikrishnan, S.2
  • 8
    • 0034636716 scopus 로고    scopus 로고
    • Exploring redundancy in the yeast genome: An improved strategy for use of the cre-loxP system
    • Delneri D, Tomlin GC, Wixon JL, Hutter A, Sefton M, Louis EJ, Oliver SG. 2000. Exploring redundancy in the yeast genome: An improved strategy for use of the cre-loxP system. Gene 252(1-2):127-135.
    • (2000) Gene , vol.252 , Issue.1-2 , pp. 127-135
    • Delneri, D.1    Tomlin, G.C.2    Wixon, J.L.3    Hutter, A.4    Sefton, M.5    Louis, E.J.6    Oliver, S.G.7
  • 10
    • 0033591216 scopus 로고    scopus 로고
    • The LPP1 and DPP1 gene products account for most of the isoprenoid phosphate phosphatase activities in Saccharomyces cerevisiae
    • Faulkner A, Chen X, Rush J, Horazdovsky B, Waechter CJ, Carman GM, Sternweis PC. 1999. The LPP1 and DPP1 gene products account for most of the isoprenoid phosphate phosphatase activities in Saccharomyces cerevisiae. J Biol Chem 274(21):14831-14837.
    • (1999) J Biol Chem , vol.274 , Issue.21 , pp. 14831-14837
    • Faulkner, A.1    Chen, X.2    Rush, J.3    Horazdovsky, B.4    Waechter, C.J.5    Carman, G.M.6    Sternweis, P.C.7
  • 11
    • 0023803638 scopus 로고
    • Cooperative DNA binding of the yeast transcriptional activator GAL4
    • Giniger E, Ptashne M. 1988. Cooperative DNA binding of the yeast transcriptional activator GAL4. Proc Natl Acad Sci USA 85(2):382-386.
    • (1988) Proc Natl Acad Sci USA , vol.85 , Issue.2 , pp. 382-386
    • Giniger, E.1    Ptashne, M.2
  • 12
    • 0037088811 scopus 로고    scopus 로고
    • A second set of loxP marker cassettes for cre-mediated multiple gene knockouts in budding yeast
    • Gueldener U, Heinisch J, Koehler G, Voss D, Hegemann J. 2002. A second set of loxP marker cassettes for cre-mediated multiple gene knockouts in budding yeast. Nucleic Acids Res 30(6):e23-e23.
    • (2002) Nucleic Acids Res , vol.30 , Issue.6
    • Gueldener, U.1    Heinisch, J.2    Koehler, G.3    Voss, D.4    Hegemann, J.5
  • 13
    • 0029994841 scopus 로고    scopus 로고
    • A new efficient gene disruption cassette for repeated use in budding yeast
    • Guldener U, Heck S, Fiedler T, Beinhauer J, Hegemann JH. 1996. A new efficient gene disruption cassette for repeated use in budding yeast. Nucleic Acids Res 24(13):2519-2524.
    • (1996) Nucleic Acids Res , vol.24 , Issue.13 , pp. 2519-2524
    • Guldener, U.1    Heck, S.2    Fiedler, T.3    Beinhauer, J.4    Hegemann, J.H.5
  • 14
    • 0036187741 scopus 로고    scopus 로고
    • Overproduction of pentose phosphate pathway enzymes using a new CRE-loxP expression vector for repeated genomic integration in Saccharomyces cerevisiae
    • Johansson B, Hahn-Hagerdal B. 2002. Overproduction of pentose phosphate pathway enzymes using a new CRE-loxP expression vector for repeated genomic integration in Saccharomyces cerevisiae. Yeast 19(3):225-231.
    • (2002) Yeast , vol.19 , Issue.3 , pp. 225-231
    • Johansson, B.1    Hahn-Hagerdal, B.2
  • 15
    • 0028230982 scopus 로고
    • Multiple mechanisms provide rapid and stringent glucose repression of GAL gene expression in Saccharomyces cerevisiae
    • Johnston M, Flick JS, Pexton T. 1994. Multiple mechanisms provide rapid and stringent glucose repression of GAL gene expression in Saccharomyces cerevisiae. Mol Cell Biol 14(6):3834-3841.
    • (1994) Mol Cell Biol , vol.14 , Issue.6 , pp. 3834-3841
    • Johnston, M.1    Flick, J.S.2    Pexton, T.3
  • 16
    • 84872415347 scopus 로고    scopus 로고
    • Characterization of plasmid burden and copy number in Saccharomyces cerevisiae for optimization of metabolic engineering applications
    • Karim AS, Curran KA, Alper HS. 2013. Characterization of plasmid burden and copy number in Saccharomyces cerevisiae for optimization of metabolic engineering applications. FEMS Yeast Res 13(1):107-116.
    • (2013) FEMS Yeast Res , vol.13 , Issue.1 , pp. 107-116
    • Karim, A.S.1    Curran, K.A.2    Alper, H.S.3
  • 17
    • 84859772410 scopus 로고    scopus 로고
    • Synthetic biology and the development of tools for metabolic engineering
    • Keasling JD. 2012. Synthetic biology and the development of tools for metabolic engineering. Metab Eng 14(3):189-195.
    • (2012) Metab Eng , vol.14 , Issue.3 , pp. 189-195
    • Keasling, J.D.1
  • 18
    • 0037178722 scopus 로고    scopus 로고
    • Maintenance of genome stability in Saccharomyces cerevisiae
    • Kolodner RD, Putnam CD, Myung K. 2002. Maintenance of genome stability in Saccharomyces cerevisiae. Science 297(5581):552-557.
    • (2002) Science , vol.297 , Issue.5581 , pp. 552-557
    • Kolodner, R.D.1    Putnam, C.D.2    Myung, K.3
  • 19
    • 79952123299 scopus 로고    scopus 로고
    • Opportunities for yeast metabolic engineering: Lessons from synthetic biology
    • Krivoruchko A, Siewers V, Nielsen J. 2011. Opportunities for yeast metabolic engineering: Lessons from synthetic biology. Biotechnol J 6(3):262-276.
    • (2011) Biotechnol J , vol.6 , Issue.3 , pp. 262-276
    • Krivoruchko, A.1    Siewers, V.2    Nielsen, J.3
  • 20
    • 0029058555 scopus 로고
    • Transcriptional regulation in the yeast GAL gene family: A complex genetic network
    • Lohr D, Venkov P, Zlatanova J. 1995. Transcriptional regulation in the yeast GAL gene family: A complex genetic network. FASEB J 9(9):777-787.
    • (1995) FASEB J , vol.9 , Issue.9 , pp. 777-787
    • Lohr, D.1    Venkov, P.2    Zlatanova, J.3
  • 21
    • 0038391517 scopus 로고    scopus 로고
    • Engineering a mevalonate pathway in Escherichia coli for production of terpenoids
    • Martin VJ, Pitera DJ, Withers ST, Newman JD, Keasling JD. 2003. Engineering a mevalonate pathway in Escherichia coli for production of terpenoids. Nat Biotechnol 21(7):796-802.
    • (2003) Nat Biotechnol , vol.21 , Issue.7 , pp. 796-802
    • Martin, V.J.1    Pitera, D.J.2    Withers, S.T.3    Newman, J.D.4    Keasling, J.D.5
  • 22
    • 56949088585 scopus 로고    scopus 로고
    • Reconstruction of a bacterial isoprenoid biosynthetic pathway in Saccharomyces cerevisiae
    • Maury J, Asadollahi MA, Moller K, Schalk M, Clark A, Formenti LR, Nielsen J. 2008. Reconstruction of a bacterial isoprenoid biosynthetic pathway in Saccharomyces cerevisiae. FEBS Lett 582(29):4032-4038.
    • (2008) FEBS Lett , vol.582 , Issue.29 , pp. 4032-4038
    • Maury, J.1    Asadollahi, M.A.2    Moller, K.3    Schalk, M.4    Clark, A.5    Formenti, L.R.6    Nielsen, J.7
  • 23
    • 0028953840 scopus 로고
    • Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds
    • Mumberg D, Muller R, Funk M. 1995. Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds. Gene 156(1):119-122.
    • (1995) Gene , vol.156 , Issue.1 , pp. 119-122
    • Mumberg, D.1    Muller, R.2    Funk, M.3
  • 24
    • 51949107835 scopus 로고    scopus 로고
    • Progress in metabolic engineering of Saccharomyces cerevisiae
    • Nevoigt E. 2008. Progress in metabolic engineering of Saccharomyces cerevisiae. Microbiol Mol Biol Rev 72(3):379-412.
    • (2008) Microbiol Mol Biol Rev , vol.72 , Issue.3 , pp. 379-412
    • Nevoigt, E.1
  • 25
    • 78149328427 scopus 로고    scopus 로고
    • Characterization of different promoters for designing a new expression vector in Saccharomyces cerevisiae
    • Partow S, Siewers V, Bjorn S, Nielsen J, Maury J. 2010. Characterization of different promoters for designing a new expression vector in Saccharomyces cerevisiae. Yeast 27(11):955-964.
    • (2010) Yeast , vol.27 , Issue.11 , pp. 955-964
    • Partow, S.1    Siewers, V.2    Bjorn, S.3    Nielsen, J.4    Maury, J.5
  • 26
    • 33847309176 scopus 로고    scopus 로고
    • Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli
    • Pitera DJ, Paddon CJ, Newman JD, Keasling JD. 2007. Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli. Metab Eng 9(2):193-207.
    • (2007) Metab Eng , vol.9 , Issue.2 , pp. 193-207
    • Pitera, D.J.1    Paddon, C.J.2    Newman, J.D.3    Keasling, J.D.4
  • 27
    • 0031962865 scopus 로고    scopus 로고
    • Overexpression of a cytosolic hydroxymethylglutaryl-CoA reductase leads to squalene accumulation in yeast
    • Polakowski T, Stahl U, Lang C. 1998. Overexpression of a cytosolic hydroxymethylglutaryl-CoA reductase leads to squalene accumulation in yeast. Appl Microbiol Biotechnol 49(1):66-71.
    • (1998) Appl Microbiol Biotechnol , vol.49 , Issue.1 , pp. 66-71
    • Polakowski, T.1    Stahl, U.2    Lang, C.3
  • 28
    • 79551667941 scopus 로고    scopus 로고
    • Circular polymerase extension cloning for high-throughput cloning of complex and combinatorial DNA libraries
    • Quan JY, Tian JD. 2011. Circular polymerase extension cloning for high-throughput cloning of complex and combinatorial DNA libraries. Nat Protocols 6(2):242-251.
    • (2011) Nat Protocols , vol.6 , Issue.2 , pp. 242-251
    • Quan, J.Y.1    Tian, J.D.2
  • 29
    • 0036270546 scopus 로고    scopus 로고
    • Cloning-free genome alterations in Saccharomyces cerevisiae using adaptamer-mediated PCR
    • Reid RJ, Lisby M, Rothstein R. 2002. Cloning-free genome alterations in Saccharomyces cerevisiae using adaptamer-mediated PCR. Methods Enzymol 350:258-277.
    • (2002) Methods Enzymol , vol.350 , pp. 258-277
    • Reid, R.J.1    Lisby, M.2    Rothstein, R.3
  • 30
    • 0026778048 scopus 로고
    • Foreign gene-expression in yeast-A review
    • Romanos MA, Scorer CA, Clare JJ. 1992. Foreign gene-expression in yeast-A review. Yeast 8(6):423-488.
    • (1992) Yeast , vol.8 , Issue.6 , pp. 423-488
    • Romanos, M.A.1    Scorer, C.A.2    Clare, J.J.3
  • 31
    • 84862827747 scopus 로고    scopus 로고
    • Dynamic control of gene expression in Saccharomyces cerevisiae engineered for the production of plant sesquitepene alpha-santalene in a fed-batch mode
    • Scalcinati G, Knuf C, Partow S, Chen Y, Maury J, Schalk M, Daviet L, Nielsen J, Siewers V. 2012. Dynamic control of gene expression in Saccharomyces cerevisiae engineered for the production of plant sesquitepene alpha-santalene in a fed-batch mode. Metab Eng 14(2):91-103.
    • (2012) Metab Eng , vol.14 , Issue.2 , pp. 91-103
    • Scalcinati, G.1    Knuf, C.2    Partow, S.3    Chen, Y.4    Maury, J.5    Schalk, M.6    Daviet, L.7    Nielsen, J.8    Siewers, V.9
  • 32
    • 77953069866 scopus 로고    scopus 로고
    • Detection and measurement of carotenoids by UV/VIS spectrophotometry
    • In: New York: John Wiley & Sons.
    • Scott KJ. 2001. Detection and measurement of carotenoids by UV/VIS spectrophotometry. In: Current Protocols in Food Analytical Chemistry. New York: John Wiley & Sons. p F2.2.1-F2.2.10.
    • (2001) Current Protocols in Food Analytical Chemistry
    • Scott, K.J.1
  • 34
    • 59649108349 scopus 로고    scopus 로고
    • DNA assembler, an in vivo genetic method for rapid construction of biochemical pathways
    • Shao ZY, Zhao H, Zhao HM. 2009. DNA assembler, an in vivo genetic method for rapid construction of biochemical pathways. Nucleic Acids Res 37(2):e16-e16.
    • (2009) Nucleic Acids Res , vol.37 , Issue.2
    • Shao, Z.Y.1    Zhao, H.2    Zhao, H.M.3
  • 35
    • 33847378479 scopus 로고    scopus 로고
    • Engineering of the pyruvate dehydrogenase bypass in Saccharomyces cerevisiae for high-level production of isoprenoids
    • Shiba Y, Paradise EM, Kirby J, Ro DK, Keasling JD. 2007. Engineering of the pyruvate dehydrogenase bypass in Saccharomyces cerevisiae for high-level production of isoprenoids. Metab Eng 9(2):160-168.
    • (2007) Metab Eng , vol.9 , Issue.2 , pp. 160-168
    • Shiba, Y.1    Paradise, E.M.2    Kirby, J.3    Ro, D.K.4    Keasling, J.D.5
  • 36
    • 84857048835 scopus 로고    scopus 로고
    • Advancing secondary metabolite biosynthesis in yeast with synthetic biology tools
    • Siddiqui MS, Thodey K, Trenchard I, Smolke CD. 2012. Advancing secondary metabolite biosynthesis in yeast with synthetic biology tools. FEMS Yeast Res 12(2):144-170.
    • (2012) FEMS Yeast Res , vol.12 , Issue.2 , pp. 144-170
    • Siddiqui, M.S.1    Thodey, K.2    Trenchard, I.3    Smolke, C.D.4
  • 38
    • 80052626818 scopus 로고    scopus 로고
    • Beta-Carotene production by Saccharomyces cerevisiae with regard to plasmid stability and culture media
    • Steinbuchel A, Lange N. 2011. Beta-Carotene production by Saccharomyces cerevisiae with regard to plasmid stability and culture media. Appl Microbiol Biotechnol 91(6):1611-1622.
    • (2011) Appl Microbiol Biotechnol , vol.91 , Issue.6 , pp. 1611-1622
    • Steinbuchel, A.1    Lange, N.2
  • 39
    • 84862817382 scopus 로고    scopus 로고
    • Cloning and characterization of a panel of constitutive promoters for applications in pathway engineering in Saccharomyces cerevisiae
    • Sun J, Shao Z, Zhao H, Nair N, Wen F, Xu JH. 2012. Cloning and characterization of a panel of constitutive promoters for applications in pathway engineering in Saccharomyces cerevisiae. Biotechnol Bioeng 109(8):2082-2092.
    • (2012) Biotechnol Bioeng , vol.109 , Issue.8 , pp. 2082-2092
    • Sun, J.1    Shao, Z.2    Zhao, H.3    Nair, N.4    Wen, F.5    Xu, J.H.6
  • 41
    • 33745195271 scopus 로고    scopus 로고
    • Yeast Gal4: A transcriptional paradigm revisited
    • Traven A, Jelicic B, Sopta M. 2006. Yeast Gal4: A transcriptional paradigm revisited. EMBO Rep 7(5):496-499.
    • (2006) EMBO Rep , vol.7 , Issue.5 , pp. 496-499
    • Traven, A.1    Jelicic, B.2    Sopta, M.3
  • 42
    • 0032722810 scopus 로고    scopus 로고
    • Isolation and functional characterisation of a novel type of carotenoid biosynthetic gene from Xanthophyllomyces dendrorhous
    • Verdoes JC, Krubasik P, Sandmann G, van Ooyen AJJ. 1999a. Isolation and functional characterisation of a novel type of carotenoid biosynthetic gene from Xanthophyllomyces dendrorhous. Mol Gen Genet 262(3):453-461.
    • (1999) Mol Gen Genet , vol.262 , Issue.3 , pp. 453-461
    • Verdoes, J.C.1    Krubasik, P.2    Sandmann, G.3    van Ooyen, A.J.J.4
  • 43
    • 0033587374 scopus 로고    scopus 로고
    • Cloning and characterization of the astaxanthin biosynthetic gene encoding phytoene desaturase of Xanthophyllomyces dendrorhous
    • Verdoes JC, Misawa N, van Ooyen AJ. 1999b. Cloning and characterization of the astaxanthin biosynthetic gene encoding phytoene desaturase of Xanthophyllomyces dendrorhous. Biotechnol Bioeng 63(6):750-755.
    • (1999) Biotechnol Bioeng , vol.63 , Issue.6 , pp. 750-755
    • Verdoes, J.C.1    Misawa, N.2    van Ooyen, A.J.3
  • 44
    • 34447543117 scopus 로고    scopus 로고
    • High-level production of beta-carotene in Saccharomyces cerevisiae by successive transformation with carotenogenic genes from Xanthophyllomyces dendrorhous
    • Verwaal R, Wang J, Meijnen JP, Visser H, Sandmann G, van den Berg JA, van Ooyen AJJ. 2007. High-level production of beta-carotene in Saccharomyces cerevisiae by successive transformation with carotenogenic genes from Xanthophyllomyces dendrorhous. Appl Environ Microbiol 73(13):4342-4350.
    • (2007) Appl Environ Microbiol , vol.73 , Issue.13 , pp. 4342-4350
    • Verwaal, R.1    Wang, J.2    Meijnen, J.P.3    Visser, H.4    Sandmann, G.5    van den Berg, J.A.6    van Ooyen, A.J.J.7
  • 45
    • 0029871347 scopus 로고    scopus 로고
    • PCR-synthesis of marker cassettes with long flanking homology regions for gene disruptions in S. cerevisiae
    • Wach A. 1996. PCR-synthesis of marker cassettes with long flanking homology regions for gene disruptions in S. cerevisiae. Yeast 12(3):259-265.
    • (1996) Yeast , vol.12 , Issue.3 , pp. 259-265
    • Wach, A.1
  • 46
    • 80053064386 scopus 로고    scopus 로고
    • Reiterative recombination for the in vivo assembly of libraries of multigene pathways
    • Wingler LM, Cornish VW. 2011. Reiterative recombination for the in vivo assembly of libraries of multigene pathways. Proc Natl Acad Sci USA 108(37):15135-15140.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.37 , pp. 15135-15140
    • Wingler, L.M.1    Cornish, V.W.2
  • 47
    • 84856962877 scopus 로고    scopus 로고
    • Enhanced production of β-carotene by recombinant industrial wine yeast using grape juice as substrate
    • Yan G, Liang H, Duan C, Han B. 2011. Enhanced production of β-carotene by recombinant industrial wine yeast using grape juice as substrate. Curr Microbiol 64(2):152-158.
    • (2011) Curr Microbiol , vol.64 , Issue.2 , pp. 152-158
    • Yan, G.1    Liang, H.2    Duan, C.3    Han, B.4
  • 49
    • 0030308931 scopus 로고    scopus 로고
    • Plasmid stability in recombinant Saccharomyces cerevisiae
    • Zhang Z, Moo-Young M, Chisti Y. 1996. Plasmid stability in recombinant Saccharomyces cerevisiae. Biotechnol Adv 14(4):401-435.
    • (1996) Biotechnol Adv , vol.14 , Issue.4 , pp. 401-435
    • Zhang, Z.1    Moo-Young, M.2    Chisti, Y.3


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