β-Carotene production by Saccharomyces cerevisiae with regard to plasmid stability and culture media

Applied Microbiology and Biotechnology

Volumn 91, Issue 6, 2011, Pages 1611-1622

  Lange, Nicole ^a   Steinbüchel, Alexander ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

carotene; Carotenoids; Mevalonate (MVA) pathway; Mevalonate kinase; Plasmid stability; Saccharomyces cerevisiae

Indexed keywords

CAROTENE PRODUCTION; CAROTENOID PRODUCTION; CAROTENOIDS; CELL DENSITY; CELL DRY MATTER; CULTIVATION CONDITIONS; CULTIVATION PERIODS; CULTURE MEDIA; DELETION MUTANTS; GENE CODING; MEVALONATE; MEVALONATE KINASE; PLASMID STABILITY; RECOMBINANT STRAINS; RECOMBINANT YEAST; S.CEREVISIAE; SACCHAROMYCES CEREVISIAE STRAINS; SOLE CARBON SOURCE; STAPHYLOCOCCUS AUREUS; TIME-COURSE EXPERIMENTS; XANTHOPHYLLOMYCES DENDRORHOUS;

BACTERIA; CELL CULTURE; CELLS; CULTIVATION; DNA; ENZYMES; EXPERIMENTS; GENES; GLUCOSE; PIGMENTS; STABILITY;

YEAST;

BETA CAROTENE; CAROTENOID; MEVALONATE KINASE;

CARBON; CAROTENOID; CELL ORGANELLE; DRY MATTER; ENZYME ACTIVITY; GENE; GLUCOSE; PLASMID; YEAST;

ARTICLE; CELL DENSITY; CULTURE MEDIUM; FUNGAL CELL; FUNGAL STRAIN; FUNGUS CULTURE; FUNGUS GROWTH; NONHUMAN; PLASMID; PROMOTER REGION; SACCHAROMYCES CEREVISIAE; STAPHYLOCOCCUS AUREUS; XANTHOPHYLLOMYCES DENDRORHOUS; YEAST;

BETA CAROTENE; BIOSYNTHETIC PATHWAYS; CULTURE MEDIA; GENE EXPRESSION REGULATION, FUNGAL; GENETIC ENGINEERING; PLASMIDS; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE; STAPHYLOCOCCUS AUREUS; XANTHOPHYLLOMYCES DENDRORHOUS;

EID: 80052626818     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-011-3315-2     Document Type: Article

References (38)

1. GA Armstrong M Alberti F Leach JE Hearst 1989 Nucleotide sequence, organization and nature of the protein products of the carotenoid biosynthesis gene cluster of Rhodobacter capsulatus Mol Gen Genet 216 254 268 10.1007/BF00334364 1:CAS:528:DyaK3cXntFSlsA%3D%3D
2. GA Armstrong M Alberti JE Hearst 1990 Conserved enzymes mediate the early reactions of carotenoid biosynthesis in nonphotosynthetic and photosynthetic prokaryotes Proc Natl Acad Sci U S A 87 9975 9979 10.1073/pnas.87.24.9975 1:CAS:528:DyaK3MXktVWqu7Y%3D (Pubitemid 120016567)
3. Britton G, Liaaen-Jensen S, Pfander H (1995) Carotenoids volume 1a: isolation and analysis. Birkhäuser, Basel, Switzerland
4. Britton G, Liaaen-Jensen S, Pfander H (2004) Carotenoids handbook, 1st edn. Birkhäuser, Basel, Switzerland
5. JM Cherry C Ball S Weng G Juvik R Schmidt C Adler B Dunn S Dwight L Riles RK Mortimer D Botstein 1997 Genetic and physical maps of Saccharomyces cerevisiae Nature 387 67 73 10.1038/43025 1:CAS:528:DyaK2sXjsFGitbs%3D (Pubitemid 27334668)
6. GI Frengova DM Beshkova 2009 Carotenoids from Rhodotorula and Phaffia: yeasts of biotechnological importance J Ind Microbiol Biotechnol 36 163 180 10.1007/s10295-008-0492-9 1:CAS:528:DC%2BD1MXhtF2jsrY%3D
7. AB Futcher BS Cox 1984 Copy number and the stability of 2-micron circle-based artificial plasmids of Saccharomyces cerevisiae J Bacteriol 157 283 290 1:CAS:528:DyaL2cXmt1Gquw%3D%3D (Pubitemid 14222488)
8. RD Gietz RA Woods 2002 Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method Meth Enzymol 350 87 96 10.1016/S0076-6879(02)50957-5 1:CAS:528:DC%2BD38XlsVaqs7g%3D (Pubitemid 34619485)
9. A Goffeau BG Barrell H Bussey RW Davis B Dujon H Feldmann F Galibert JD Hoheisel C Jacq M Johnston EJ Louis HW Mewes Y Murakami P Philippsen H Tettelin SG Oliver 1996 Life with 6000 genes Science 274 546 563 567
10. JL Goldstein MS Brown 1990 Regulation of the mevalonate pathway Nature 343 425 430 10.1038/343425a0 1:CAS:528:DyaK3cXhtlCmtbw%3D (Pubitemid 20065229)
11. U Gueldener J Heinisch GJ Koehler D Voss JH Hegemann 2002 A second set of loxP marker cassettes for Cre-mediated multiple gene knockouts in budding yeast Nucleic Acids Res 30 e23 10.1093/nar/30.6.e23 1:STN:280:DC%2BD387lt1GnsQ%3D%3D
12. B Huang J Guo B Yi X Yu L Sun W Chen 2008 Heterologous production of secondary metabolites as pharmaceuticals in Saccharomyces cerevisiae Biotechnol Lett 30 1121 1137 10.1007/s10529-008-9663-z 1:CAS:528:DC%2BD1cXmslSqurc%3D
13. J Kirby JD Keasling 2009 Biosynthesis of plant isoprenoids: perspectives for microbial engineering Annu Rev Plant Biol 60 335 355 10.1146/annurev. arplant.043008.091955 1:CAS:528:DC%2BD1MXntFGlsL8%3D
14. J Kroll A Steinle R Reichelt C Ewering A Steinbüchel 2009 Establishment of a novel anabolism-based addiction system with an artificially introduced mevalonate pathway: complete stabilization of plasmids as universal application in white biotechnology Metab Eng 11 168 177 10.1016/j.ymben.2009.01. 007 1:CAS:528:DC%2BD1MXktlylsbs%3D
15. J Kroll S Klinter C Schneider I Vo A Steinbüchel 2010 Plasmid addiction systems: perspectives and applications in biotechnology Microb Biotechnol 3 634 657 10.1111/j.1751-7915.2010.00170.x 1:CAS:528: DC%2BC3cXhsVantrnK
16. HK Lichtenthaler 1999 The 1-deoxy-D-xylulose-5-phosphate pathway of isoprenoid biosynthesis in plants Annu Rev Plant Biol 50 47 65 10.1146/annurev.arplant.50.1.47 1:CAS:528:DyaK1MXkt1yksLo%3D (Pubitemid 30342915)
17. GN Liu YH Zhu JG Jiang 2009 The metabolomics of carotenoids in engineered cell factory Appl Microbiol Biotechnol 83 989 999 10.1007/s00253-009-2069-6 1:CAS:528:DC%2BD1MXotVGrtbc%3D
18. F Lynen 1967 Biosynthetic pathways from acetate to natural products Pure Appl Chem 14 137 167 10.1351/pac196714010137 1:CAS:528:DyaF2sXksVSjt7c%3D
19. HW Mewes K Albermann M Bahr D Frishman A Gleissner J Hani K Heumann K Kleine A Maierl SG Oliver F Pfeiffer A Zollner 1997 Overview of the yeast genome Nature 387 7 65 10.1038/42755 (Pubitemid 27270618)
20. N Misawa M Nakagawa K Kobayashi S Yamano Y Izawa K Nakamura K Harashima 1990 Elucidation of the Erwinia uredovora carotenoid biosynthetic pathway by functional analysis of gene products expressed in Escherichia coli J Bacteriol 172 6704 6712 1:CAS:528:DyaK3MXisVWntbs%3D
21. N Misawa S Yamano H Ikenaga 1991 Production of beta-carotene in Zymomonas mobilis and Agrobacterium tumefaciens by introduction of the biosynthesis genes from Erwinia uredovora Appl Environ Microbiol 57 1847 1849 1:CAS:528: DyaK3MXks12rurw%3D
22. HM Miziorko 2011 Enzymes of the mevalonate pathway of isoprenoid biosynthesis Arch Biochem Biophys 505 131 143 10.1016/j.abb.2010.09.028 1:CAS:528:DC%2BC3MXjvFOmsw%3D%3D
23. S Partow V Siewers S Bjorn J Nielsen J Maury 2010 Characterization of different promoters for designing a new expression vector in Saccharomyces cerevisiae Yeast 27 955 964 10.1002/yea.1806 1:CAS:528:DC%2BC3cXhtlOhs7nI
24. SB Primrose SD Ehrlich 1981 Isolation of plasmid deletion mutants and study of their instability Plasmid 6 193 201 10.1016/0147-619X(81)90066-4 1:CAS:528:DyaL3MXlsVOjsr0%3D (Pubitemid 12233087)
25. M Rohmer M Knani P Simonin B Sutter H Sahm 1993 Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate Biochem J 295 Pt 2 517 524 1:CAS:528:DyaK3sXms1Kit74%3D (Pubitemid 23315192)
26. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual 2nd edition. Cold Spring Harbor Laboratory Press, NY
27. L Sandager MH Gustavsson U Stahl A Dahlqvist E Wiberg A Banas M Lenman H Ronne S Stymne 2002 Storage lipid synthesis is non-essential in yeast J Biol Chem 277 6478 6482 10.1074/jbc.M109109200 1:CAS:528:DC%2BD38XhvFyqs7g%3D (Pubitemid 34968444)
28. M Scholz M Lipinski M Leupold H Luftmann L Harig R Ofir R Fischer D Prüfer KJ Müller 2009 Methyl jasmonate induced accumulation of kalopanaxsaponin I in Nigella sativa Phytochemistry 70 517 522 10.1016/j.phytochem.2009.01.018 1:CAS:528:DC%2BD1MXjsVyqsr8%3D
29. S Ugolini V Tosato CV Bruschi 2002 Selective fitness of four episomal shuttle-vectors carrying HIS3, LEU2, TRP1, and URA3 selectable markers in Saccharomyces cerevisiae Plasmid 47 94 107 10.1006/plas.2001.1557 1:CAS:528:DC%2BD38Xjt1Gisbg%3D (Pubitemid 34494385)
30. K Ukibe K Hashida N Yoshida H Takagi 2009 Metabolic engineering of Saccharomyces cerevisiae for astaxanthin production and oxidative stress tolerance Appl Environ Microbiol 75 7205 7211 10.1128/AEM.01249-09 1:CAS:528:DC%2BD1MXhsFSit7jN
31. R Verwaal J Wang JP Meijnen H Visser G Sandmann JA van den Berg AJ van Ooyen 2007 High-level production of beta-carotene in Saccharomyces cerevisiae by successive transformation with carotenogenic genes from Xanthophyllomyces dendrorhous Appl Environ Microbiol 73 4342 4350 10.1128/AEM.02759-06 1:CAS:528:DC%2BD2sXot1OrtrY%3D (Pubitemid 47068176)
32. NE Voynova SE Rios HM Miziorko 2004 Staphylococcus aureus mevalonate kinase: isolation and characterization of an enzyme of the isoprenoid biosynthetic pathway J Bacteriol 186 61 67 10.1128/JB.186.1.61-67.2004 1:CAS:528:DC%2BD2cXhsFCh (Pubitemid 38020287)
33. VH Vu K Kim 2009 High-cell-density fed-batch culture of Saccharomyces cerevisiae KV-25 using molasses and corn steep liquor J Microbiol Biotechnol 19 1603 1611 1:CAS:528:DC%2BC3cXhtF2ks78%3D
34. Walker GM (1998) Yeast physiology and biotechnology. John Wiley & Sons, New York, USA
35. S Yamano T Ishii M Nakagawa H Ikenaga N Misawa 1994 Metabolic engineering for production of beta-carotene and lycopene in Saccharomyces cerevisiae Biosci Biotechnol Biochem 58 1112 1114 10.1271/bbb.58.1112 1:CAS:528: DyaK2cXltVSrsL8%3D (Pubitemid 2118928)
36. S Yoon H Park J Kim S Lee M Choi J Kim D Oh JD Keasling S Kim 2007 Increased β-carotene production in recombinant Escherichia coli harboring an engineered isoprenoid precursor pathway with mevalonate addition Biotechnol Prog 23 599 605 10.1021/bp070012p 1:CAS:528:DC%2BD2sXlt1eitb8%3D (Pubitemid 46911183)
37. S Yoon S Lee A Das H Ryu H Jang J Kim D Oh JD Keasling S Kim 2009 Combinatorial expression of bacterial whole mevalonate pathway for the production of β-carotene in E. coli J Biotechnol 140 218 226 10.1016/j.jbiotec.2009.01.008 1:CAS:528:DC%2BD1MXjvVWjtr8%3D
38. Z Zhang M Moo-Young Y Chisti 1996 Plasmid stability in recombinant Saccharomyces cerevisiae Biotechnol Adv 14 401 435 10.1016/S0734-9750(96)00033-X 1:CAS:528:DyaK2sXisFWmtQ%3D%3D (Pubitemid 29359499)