-
1
-
-
77954638804
-
Update on human polyomaviruses and cancer
-
Gjoerup O, Chang Y. 2010. Update on human polyomaviruses and cancer. Adv. Cancer Res. 106:1-51.
-
(2010)
Adv. Cancer Res.
, vol.106
, pp. 1-51
-
-
Gjoerup, O.1
Chang, Y.2
-
2
-
-
27944459717
-
SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation
-
Ahuja D, Saenz-Robles MT, Pipas JM. 2005. SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation. Oncogene 24:7729-7745.
-
(2005)
Oncogene
, vol.24
, pp. 7729-7745
-
-
Ahuja, D.1
Saenz-Robles, M.T.2
Pipas, J.M.3
-
3
-
-
0028111651
-
The kinetics of simian virus 40-induced progression of quiescent cells into S phase depend on four independent functions of large T antigen
-
Dickmanns A, Zeitvogel A, Simmersbach F, Weber R, Arthur AK, Dehde S, Wildeman AG, Fanning E. 1994. The kinetics of simian virus 40-induced progression of quiescent cells into S phase depend on four independent functions of large T antigen. J. Virol. 68:5496-5508.
-
(1994)
J. Virol.
, vol.68
, pp. 5496-5508
-
-
Dickmanns, A.1
Zeitvogel, A.2
Simmersbach, F.3
Weber, R.4
Arthur, A.K.5
Dehde, S.6
Wildeman, A.G.7
Fanning, E.8
-
4
-
-
10744222730
-
Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1
-
Cotsiki M, Lock RL, Cheng Y, Williams GL, Zhao J, Perera D, Freire R, Entwistle A, Golemis EA, Roberts TM, Jat PS, Gjoerup OV. 2004. Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1. Proc. Natl. Acad. Sci. U.S.A. 101:947-952.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 947-952
-
-
Cotsiki, M.1
Lock, R.L.2
Cheng, Y.3
Williams, G.L.4
Zhao, J.5
Perera, D.6
Freire, R.7
Entwistle, A.8
Golemis, E.A.9
Roberts, T.M.10
Jat, P.S.11
Gjoerup, O.V.12
-
5
-
-
58149393201
-
Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding
-
Hein J, Boichuk S, Wu J, Cheng Y, Freire R, Jat PS, Roberts TM, Gjoerup OV. 2009. Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding. J. Virol. 83:117-127.
-
(2009)
J. Virol.
, vol.83
, pp. 117-127
-
-
Hein, J.1
Boichuk, S.2
Wu, J.3
Cheng, Y.4
Freire, R.5
Jat, P.S.6
Roberts, T.M.7
Gjoerup, O.V.8
-
6
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. 1998. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 273:5858-5868.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
7
-
-
77954973763
-
Multiple DNA damage signaling and repair pathways deregulated by simian virus 40 large T antigen
-
Boichuk S, Hu L, Hein J, Gjoerup OV. 2010. Multiple DNA damage signaling and repair pathways deregulated by simian virus 40 large T antigen. J. Virol. 84:8007-8020.
-
(2010)
J. Virol.
, vol.84
, pp. 8007-8020
-
-
Boichuk, S.1
Hu, L.2
Hein, J.3
Gjoerup, O.V.4
-
8
-
-
28844436714
-
Ataxiatelangiectasia-mutated (ATM) is a T-antigen kinase that controls SV40 viral replication in vivo
-
Shi Y, Dodson GE, Shaikh S, Rundell K, Tibbetts RS. 2005. Ataxiatelangiectasia-mutated (ATM) is a T-antigen kinase that controls SV40 viral replication in vivo. J. Biol. Chem. 280:40195-40200.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 40195-40200
-
-
Shi, Y.1
Dodson, G.E.2
Shaikh, S.3
Rundell, K.4
Tibbetts, R.S.5
-
9
-
-
77957199749
-
Simian virus 40 activates ATR-delta p53 signaling to override cell cycle and DNA replication control
-
Rohaly G, Korf K, Dehde S, Dornreiter I. 2010. Simian virus 40 activates ATR-delta p53 signaling to override cell cycle and DNA replication control. J. Virol. 84:10727-10747.
-
(2010)
J. Virol.
, vol.84
, pp. 10727-10747
-
-
Rohaly, G.1
Korf, K.2
Dehde, S.3
Dornreiter, I.4
-
10
-
-
43949088506
-
Ataxia telangiectasia-mutated damage-signaling kinaseand proteasome-dependent destruction of Mre11-Rad50-Nbs1 subunits in simian virus 40-infected primate cells
-
Zhao X, Madden-Fuentes RJ, Lou BX, Pipas JM, Gerhardt J, Rigell CJ, Fanning E. 2008. Ataxia telangiectasia-mutated damage-signaling kinaseand proteasome-dependent destruction of Mre11-Rad50-Nbs1 subunits in simian virus 40-infected primate cells. J. Virol. 82:5316-5328.
-
(2008)
J. Virol.
, vol.82
, pp. 5316-5328
-
-
Zhao, X.1
Madden-Fuentes, R.J.2
Lou, B.X.3
Pipas, J.M.4
Gerhardt, J.5
Rigell, C.J.6
Fanning, E.7
-
11
-
-
84876858858
-
ATM and ATR activities maintain replication fork integrity during SV40 chromatin replication
-
doi:10.1371/journal.ppat.1003283
-
Sowd GA, Li NY, Fanning E. 2013. ATM and ATR activities maintain replication fork integrity during SV40 chromatin replication. PLoS Pathog. 9:e1003283. doi:10.1371/journal.ppat.1003283.
-
(2013)
PLoS Pathog.
, vol.9
-
-
Sowd, G.A.1
Li, N.Y.2
Fanning, E.3
-
12
-
-
18444378391
-
A dual role for Bub1 in the spindle checkpoint and chromosome congression
-
Meraldi P, Sorger PK. 2005. A dual role for Bub1 in the spindle checkpoint and chromosome congression. EMBO J. 24:1621-1633.
-
(2005)
EMBO J.
, vol.24
, pp. 1621-1633
-
-
Meraldi, P.1
Sorger, P.K.2
-
13
-
-
34848910184
-
Bub1 maintains centromeric cohesion by activation of the spindle checkpoint
-
Perera D, Tilston V, Hopwood JA, Barchi M, Boot-Handford RP, Taylor SS. 2007. Bub1 maintains centromeric cohesion by activation of the spindle checkpoint. Dev. Cell 13:566-579.
-
(2007)
Dev. Cell
, vol.13
, pp. 566-579
-
-
Perera, D.1
Tilston, V.2
Hopwood, J.A.3
Barchi, M.4
Boot-Handford, R.P.5
Taylor, S.S.6
-
14
-
-
67649522162
-
Boveri revisited:chromosomal instability, aneuploidy and tumorigenesis
-
Holland AJ, Cleveland DW. 2009. Boveri revisited:chromosomal instability, aneuploidy and tumorigenesis. Nat. Rev. Mol. Cell Biol. 10:478-487.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 478-487
-
-
Holland, A.J.1
Cleveland, D.W.2
-
15
-
-
2342439525
-
Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression
-
Johnson VL, Scott MI, Holt SV, Hussein D, Taylor SS. 2004. Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression. J. Cell Sci. 117:1577-1589.
-
(2004)
J. Cell Sci.
, vol.117
, pp. 1577-1589
-
-
Johnson, V.L.1
Scott, M.I.2
Holt, S.V.3
Hussein, D.4
Taylor, S.S.5
-
16
-
-
66349124679
-
Bub1 regulates chromosome segregation in a kinetochore-independent manner
-
Klebig C, Korinth D, Meraldi P. 2009. Bub1 regulates chromosome segregation in a kinetochore-independent manner. J. Cell Biol. 185:841-858.
-
(2009)
J. Cell Biol.
, vol.185
, pp. 841-858
-
-
Klebig, C.1
Korinth, D.2
Meraldi, P.3
-
17
-
-
47249113044
-
Kinetochore-microtubule interactions "in check" by Bub1, Bub3 and BubR1:the dual task of attaching and signalling
-
Logarinho E, Bousbaa H. 2008. Kinetochore-microtubule interactions "in check" by Bub1, Bub3 and BubR1:the dual task of attaching and signalling. Cell Cycle 7:1763-1768.
-
(2008)
Cell Cycle
, vol.7
, pp. 1763-1768
-
-
Logarinho, E.1
Bousbaa, H.2
-
18
-
-
79960316552
-
Bub1 and BubR1:at the interface between chromosome attachment and the spindle checkpoint
-
Elowe S. 2011. Bub1 and BubR1:at the interface between chromosome attachment and the spindle checkpoint. Mol. Cell. Biol. 31:3085-3093.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 3085-3093
-
-
Elowe, S.1
-
19
-
-
0032546360
-
Mutations of mitotic checkpoint genes in human cancers
-
Cahill DP, Lengauer C, Yu J, Riggins GJ, Willson JK, Markowitz SD, Kinzler KW, Vogelstein B. 1998. Mutations of mitotic checkpoint genes in human cancers. Nature 392:300-303.
-
(1998)
Nature
, vol.392
, pp. 300-303
-
-
Cahill, D.P.1
Lengauer, C.2
Yu, J.3
Riggins, G.J.4
Willson, J.K.5
Markowitz, S.D.6
Kinzler, K.W.7
Vogelstein, B.8
-
20
-
-
58249094849
-
Impaired Bub1 function in vivo compromises tensiondependent checkpoint function leading to aneuploidy and tumorigenesis
-
Schliekelman M, Cowley DO, O'Quinn R, Oliver TG, Lu L, Salmon ED, Van Dyke T. 2009. Impaired Bub1 function in vivo compromises tensiondependent checkpoint function leading to aneuploidy and tumorigenesis. Cancer Res. 69:45-54.
-
(2009)
Cancer Res.
, vol.69
, pp. 45-54
-
-
Schliekelman, M.1
Cowley, D.O.2
O'Quinn, R.3
Oliver, T.G.4
Lu, L.5
Salmon, E.D.6
Van Dyke, T.7
-
21
-
-
35548957419
-
Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis
-
Jeganathan K, Malureanu L, Baker DJ, Abraham SC, van Deursen JM. 2007. Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis. J. Cell Biol. 179:255-267.
-
(2007)
J. Cell Biol.
, vol.179
, pp. 255-267
-
-
Jeganathan, K.1
Malureanu, L.2
Baker, D.J.3
Abraham, S.C.4
van Deursen, J.M.5
-
22
-
-
79959416796
-
Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation
-
Ricke RM, Jeganathan KB, van Deursen JM. 2011. Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation. J. Cell Biol. 193:1049-1064.
-
(2011)
J. Cell Biol.
, vol.193
, pp. 1049-1064
-
-
Ricke, R.M.1
Jeganathan, K.B.2
van Deursen, J.M.3
-
23
-
-
70749158525
-
Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity
-
Baker DJ, Jin F, Jeganathan KB, van Deursen JM. 2009. Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity. Cancer Cell 16:475-486.
-
(2009)
Cancer Cell
, vol.16
, pp. 475-486
-
-
Baker, D.J.1
Jin, F.2
Jeganathan, K.B.3
van Deursen, J.M.4
-
24
-
-
0030920846
-
Disregulation of mitotic checkpoints and regulatory proteins following acute expression of SV40 large T antigen in diploid human cells
-
Chang TH, Ray FA, Thompson DA, Schlegel R. 1997. Disregulation of mitotic checkpoints and regulatory proteins following acute expression of SV40 large T antigen in diploid human cells. Oncogene 14:2383-2393.
-
(1997)
Oncogene
, vol.14
, pp. 2383-2393
-
-
Chang, T.H.1
Ray, F.A.2
Thompson, D.A.3
Schlegel, R.4
-
25
-
-
0026773366
-
Simian virus 40 large T-antigen function is required for induction of tetraploid DNA content during lytic infection
-
Friedrich TD, Laffin J, Lehman JM. 1992. Simian virus 40 large T-antigen function is required for induction of tetraploid DNA content during lytic infection. J. Virol. 66:4576-4579.
-
(1992)
J. Virol.
, vol.66
, pp. 4576-4579
-
-
Friedrich, T.D.1
Laffin, J.2
Lehman, J.M.3
-
26
-
-
0026458549
-
SV40 T antigen induced chromosomal changes reflect a process that is both clastogenic and aneuploidogenic and is ongoing throughout neoplastic progression of human fibroblasts
-
Ray FA, Meyne J, Kraemer PM. 1992. SV40 T antigen induced chromosomal changes reflect a process that is both clastogenic and aneuploidogenic and is ongoing throughout neoplastic progression of human fibroblasts. Mutat. Res. 284:265-273.
-
(1992)
Mutat. Res.
, vol.284
, pp. 265-273
-
-
Ray, F.A.1
Meyne, J.2
Kraemer, P.M.3
-
27
-
-
0025115324
-
SV40 T antigen alone drives karyotype instability that precedes neoplastic transformation of human diploid fibroblasts
-
Ray FA, Peabody DS, Cooper JL, Cram LS, Kraemer PM. 1990. SV40 T antigen alone drives karyotype instability that precedes neoplastic transformation of human diploid fibroblasts. J. Cell. Biochem. 42:13-31.
-
(1990)
J. Cell. Biochem.
, vol.42
, pp. 13-31
-
-
Ray, F.A.1
Peabody, D.S.2
Cooper, J.L.3
Cram, L.S.4
Kraemer, P.M.5
-
28
-
-
0026053363
-
Expression of SV40 large T antigen, but not small t antigen, is required for the induction of chromosomal aberrations in transformed human cells
-
Stewart N, Bacchetti S. 1991. Expression of SV40 large T antigen, but not small t antigen, is required for the induction of chromosomal aberrations in transformed human cells. Virology 180:49-57.
-
(1991)
Virology
, vol.180
, pp. 49-57
-
-
Stewart, N.1
Bacchetti, S.2
-
29
-
-
0028030796
-
Induction of genomic instability in SV40 transformed human cells:sufficiency of the N-terminal 147 amino acids of large T antigen and role of pRB and p53
-
Woods C, LeFeuvre C, Stewart N, Bacchetti S. 1994. Induction of genomic instability in SV40 transformed human cells:sufficiency of the N-terminal 147 amino acids of large T antigen and role of pRB and p53. Oncogene 9:2943-2950.
-
(1994)
Oncogene
, vol.9
, pp. 2943-2950
-
-
Woods, C.1
LeFeuvre, C.2
Stewart, N.3
Bacchetti, S.4
-
30
-
-
34347256386
-
Surveillance mechanism linking Bub1 loss to the p53 pathway
-
Gjoerup OV, Wu J, Chandler-Militello D, Williams GL, Zhao J, Schaffhausen B, Jat PS, Roberts TM. 2007. Surveillance mechanism linking Bub1 loss to the p53 pathway. Proc. Natl. Acad. Sci. U.S.A. 104:8334-8339.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 8334-8339
-
-
Gjoerup, O.V.1
Wu, J.2
Chandler-Militello, D.3
Williams, G.L.4
Zhao, J.5
Schaffhausen, B.6
Jat, P.S.7
Roberts, T.M.8
-
31
-
-
75149140916
-
Mitotic chromosomal instability and cancer:mouse modelling of the human disease
-
Schvartzman JM, Sotillo R, Benezra R. 2010. Mitotic chromosomal instability and cancer:mouse modelling of the human disease. Nat. Rev. Cancer 10:102-115.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 102-115
-
-
Schvartzman, J.M.1
Sotillo, R.2
Benezra, R.3
-
32
-
-
84872026180
-
Linking abnormal mitosis to the acquisition of DNA damage
-
Ganem NJ, Pellman D. 2012. Linking abnormal mitosis to the acquisition of DNA damage. J. Cell Biol. 199:871-881.
-
(2012)
J. Cell Biol.
, vol.199
, pp. 871-881
-
-
Ganem, N.J.1
Pellman, D.2
-
33
-
-
84874362586
-
Replication stress links structural and numerical cancer chromosomal instability
-
Burrell RA, McClelland SE, Endesfelder D, Groth P, Weller MC, Shaikh N, Domingo E, Kanu N, Dewhurst SM, Gronroos E, Chew SK, Rowan AJ, Schenk A, Sheffer M, Howell M, Kschischo M, Behrens A, Helleday T, Bartek J, Tomlinson IP, Swanton C. 2013. Replication stress links structural and numerical cancer chromosomal instability. Nature 494:492-496.
-
(2013)
Nature
, vol.494
, pp. 492-496
-
-
Burrell, R.A.1
McClelland, S.E.2
Endesfelder, D.3
Groth, P.4
Weller, M.C.5
Shaikh, N.6
Domingo, E.7
Kanu, N.8
Dewhurst, S.M.9
Gronroos, E.10
Chew, S.K.11
Rowan, A.J.12
Schenk, A.13
Sheffer, M.14
Howell, M.15
Kschischo, M.16
Behrens, A.17
Helleday, T.18
Bartek, J.19
Tomlinson, I.P.20
Swanton, C.21
more..
-
34
-
-
77952526077
-
DNA lesions induced by replication stress trigger mitotic aberration and tetraploidy development
-
doi:10.1371/journal.pone.0008821
-
Ichijima Y, Yoshioka K, Yoshioka Y, Shinohe K, Fujimori H, Unno J, Takagi M, Goto H, Inagaki M, Mizutani S, Teraoka H. 2010. DNA lesions induced by replication stress trigger mitotic aberration and tetraploidy development. PLoS One 5:e8821. doi:10.1371/journal.pone.0008821.
-
(2010)
PLoS One
, vol.5
-
-
Ichijima, Y.1
Yoshioka, K.2
Yoshioka, Y.3
Shinohe, K.4
Fujimori, H.5
Unno, J.6
Takagi, M.7
Goto, H.8
Inagaki, M.9
Mizutani, S.10
Teraoka, H.11
-
35
-
-
80053364894
-
Chromosome segregation errors as a cause ofDNAdamage and structural chromosome aberrations
-
Janssen A, van der Burg M, Szuhai K, Kops GJ, Medema RH. 2011. Chromosome segregation errors as a cause ofDNAdamage and structural chromosome aberrations. Science 333:1895-1898.
-
(2011)
Science
, vol.333
, pp. 1895-1898
-
-
Janssen, A.1
van der Burg, M.2
Szuhai, K.3
Kops, G.J.4
Medema, R.H.5
-
36
-
-
84884891363
-
DNA damage associated with mitosis and cytokinesis failure
-
Hayashi MT, Karlseder J. 2013. DNA damage associated with mitosis and cytokinesis failure. Oncogene 32:4593-4601.
-
(2013)
Oncogene
, vol.32
, pp. 4593-4601
-
-
Hayashi, M.T.1
Karlseder, J.2
-
37
-
-
3543013739
-
Resolution of anaphase bridges in cancer cells
-
Hoffelder DR, Luo L, Burke NA, Watkins SC, Gollin SM, Saunders WS. 2004. Resolution of anaphase bridges in cancer cells. Chromosoma 112:389-397.
-
(2004)
Chromosoma
, vol.112
, pp. 389-397
-
-
Hoffelder, D.R.1
Luo, L.2
Burke, N.A.3
Watkins, S.C.4
Gollin, S.M.5
Saunders, W.S.6
-
38
-
-
84856424908
-
DNA breaks and chromosome pulverization from errors in mitosis
-
Crasta K, Ganem NJ, Dagher R, Lantermann AB, Ivanova EV, Pan Y, Nezi L, Protopopov A, Chowdhury D, Pellman D. 2012. DNA breaks and chromosome pulverization from errors in mitosis. Nature 482:53-58.
-
(2012)
Nature
, vol.482
, pp. 53-58
-
-
Crasta, K.1
Ganem, N.J.2
Dagher, R.3
Lantermann, A.B.4
Ivanova, E.V.5
Pan, Y.6
Nezi, L.7
Protopopov, A.8
Chowdhury, D.9
Pellman, D.10
-
39
-
-
79952303452
-
The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo
-
Meerbrey KL, Hu G, Kessler JD, Roarty K, Li MZ, Fang JE, Herschkowitz JI, Burrows AE, Ciccia A, Sun T, Schmitt EM, Bernardi RJ, Fu X, Bland CS, Cooper TA, Schiff R, Rosen JM, Westbrook TF, Elledge SJ. 2011. The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo. Proc. Natl. Acad. Sci. U.S.A. 108:3665-3670.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 3665-3670
-
-
Meerbrey, K.L.1
Hu, G.2
Kessler, J.D.3
Roarty, K.4
Li, M.Z.5
Fang, J.E.6
Herschkowitz, J.I.7
Burrows, A.E.8
Ciccia, A.9
Sun, T.10
Schmitt, E.M.11
Bernardi, R.J.12
Fu, X.13
Bland, C.S.14
Cooper, T.A.15
Schiff, R.16
Rosen, J.M.17
Westbrook, T.F.18
Elledge, S.J.19
-
40
-
-
79955525482
-
Nucleotide deficiency promotes genomic instability in early stages of cancer development
-
Bester AC, Roniger M, Oren YS, Im MM, Sarni D, Chaoat M, Bensimon A, Zamir G, Shewach DS, Kerem B. 2011. Nucleotide deficiency promotes genomic instability in early stages of cancer development. Cell 145:435-446.
-
(2011)
Cell
, vol.145
, pp. 435-446
-
-
Bester, A.C.1
Roniger, M.2
Oren, Y.S.3
Im, M.M.4
Sarni, D.5
Chaoat, M.6
Bensimon, A.7
Zamir, G.8
Shewach, D.S.9
Kerem, B.10
-
41
-
-
14444277241
-
DnaJ/ hsp40 chaperone domain of SV40 large T antigen promotes efficient viral DNA replication
-
Campbell KS, Mullane KP, Aksoy IA, Stubdal H, Zalvide J, Pipas JM, Silver PA, Roberts TM, Schaffhausen BS, DeCaprio JA. 1997. DnaJ/ hsp40 chaperone domain of SV40 large T antigen promotes efficient viral DNA replication. Genes Dev. 11:1098-1110.
-
(1997)
Genes Dev.
, vol.11
, pp. 1098-1110
-
-
Campbell, K.S.1
Mullane, K.P.2
Aksoy, I.A.3
Stubdal, H.4
Zalvide, J.5
Pipas, J.M.6
Silver, P.A.7
Roberts, T.M.8
Schaffhausen, B.S.9
DeCaprio, J.A.10
-
42
-
-
11144235699
-
Human Bub1 protects centromeric sister-chromatid cohesion through Shugoshin during mitosis
-
Tang Z, Sun Y, Harley SE, Zou H, Yu H. 2004. Human Bub1 protects centromeric sister-chromatid cohesion through Shugoshin during mitosis. Proc. Natl. Acad. Sci. U.S.A. 101:18012-18017.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 18012-18017
-
-
Tang, Z.1
Sun, Y.2
Harley, S.E.3
Zou, H.4
Yu, H.5
-
43
-
-
74249093169
-
Phosphorylation of H2A by Bub1 prevents chromosomal instability through localizing shugoshin
-
Kawashima SA, Yamagishi Y, Honda T, Ishiguro K, Watanabe Y. 2010. Phosphorylation of H2A by Bub1 prevents chromosomal instability through localizing shugoshin. Science 327:172-177.
-
(2010)
Science
, vol.327
, pp. 172-177
-
-
Kawashima, S.A.1
Yamagishi, Y.2
Honda, T.3
Ishiguro, K.4
Watanabe, Y.5
-
44
-
-
58149196468
-
Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit
-
Huang H, Hittle J, Zappacosta F, Annan RS, Hershko A, Yen TJ. 2008. Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit. J. Cell Biol. 183:667-680.
-
(2008)
J. Cell Biol.
, vol.183
, pp. 667-680
-
-
Huang, H.1
Hittle, J.2
Zappacosta, F.3
Annan, R.S.4
Hershko, A.5
Yen, T.J.6
-
45
-
-
40849149557
-
Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers
-
Barber TD, McManus K, Yuen KW, Reis M, Parmigiani G, Shen D, Barrett I, Nouhi Y, Spencer F, Markowitz S, Velculescu VE, Kinzler KW, Vogelstein B, Lengauer C, Hieter P. 2008. Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers. Proc. Natl. Acad. Sci. U.S.A. 105:3443-3448.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 3443-3448
-
-
Barber, T.D.1
McManus, K.2
Yuen, K.W.3
Reis, M.4
Parmigiani, G.5
Shen, D.6
Barrett, I.7
Nouhi, Y.8
Spencer, F.9
Markowitz, S.10
Velculescu, V.E.11
Kinzler, K.W.12
Vogelstein, B.13
Lengauer, C.14
Hieter, P.15
-
46
-
-
40849096242
-
Examining the link between chromosomal instability and aneuploidy in human cells
-
Thompson SL, Compton DA. 2008. Examining the link between chromosomal instability and aneuploidy in human cells. J. Cell Biol. 180:665-672.
-
(2008)
J. Cell Biol.
, vol.180
, pp. 665-672
-
-
Thompson, S.L.1
Compton, D.A.2
-
47
-
-
84055176499
-
Chromosomal instability substantiates poor prognosis in patients with diffuse large B-cell lymphoma
-
Bakhoum SF, Danilova OV, Kaur P, Levy NB, Compton DA. 2011. Chromosomal instability substantiates poor prognosis in patients with diffuse large B-cell lymphoma. Clin. Cancer Res. 17:7704-7711.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 7704-7711
-
-
Bakhoum, S.F.1
Danilova, O.V.2
Kaur, P.3
Levy, N.B.4
Compton, D.A.5
-
48
-
-
0642336728
-
Analysis of anaphase figures in routine histologic sections distinguishes chromosomally unstable from chromosomally stable malignancies
-
Montgomery E, Wilentz RE, Argani P, Fisher C, Hruban RH, Kern SE, Lengauer C. 2003. Analysis of anaphase figures in routine histologic sections distinguishes chromosomally unstable from chromosomally stable malignancies. Cancer Biol. Ther. 2:248-252.
-
(2003)
Cancer Biol. Ther.
, vol.2
, pp. 248-252
-
-
Montgomery, E.1
Wilentz, R.E.2
Argani, P.3
Fisher, C.4
Hruban, R.H.5
Kern, S.E.6
Lengauer, C.7
-
49
-
-
0034632717
-
Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
-
Artandi SE, Chang S, Lee SL, Alson S, Gottlieb GJ, Chin L, DePinho RA. 2000. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature 406:641-645.
-
(2000)
Nature
, vol.406
, pp. 641-645
-
-
Artandi, S.E.1
Chang, S.2
Lee, S.L.3
Alson, S.4
Gottlieb, G.J.5
Chin, L.6
DePinho, R.A.7
-
50
-
-
12944329959
-
Chromosomal breakage-fusion-bridge events cause genetic intratumor heterogeneity
-
Gisselsson D, Pettersson L, Hoglund M, Heidenblad M, Gorunova L, Wiegant J, Mertens F, Dal Cin P, Mitelman F, Mandahl N. 2000. Chromosomal breakage-fusion-bridge events cause genetic intratumor heterogeneity. Proc. Natl. Acad. Sci. U.S.A. 97:5357-5362.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 5357-5362
-
-
Gisselsson, D.1
Pettersson, L.2
Hoglund, M.3
Heidenblad, M.4
Gorunova, L.5
Wiegant, J.6
Mertens, F.7
Dal Cin, P.8
Mitelman, F.9
Mandahl, N.10
-
51
-
-
0032919559
-
Micronuclei formation and aneuploidy induced by Vpr, an accessory gene of human immunodeficiency virus type 1
-
Shimura M, Tanaka Y, Nakamura S, Minemoto Y, Yamashita K, Hatake K, Takaku F, Ishizaka Y. 1999. Micronuclei formation and aneuploidy induced by Vpr, an accessory gene of human immunodeficiency virus type 1. FASEB J. 13:621-637.
-
(1999)
FASEB J.
, vol.13
, pp. 621-637
-
-
Shimura, M.1
Tanaka, Y.2
Nakamura, S.3
Minemoto, Y.4
Yamashita, K.5
Hatake, K.6
Takaku, F.7
Ishizaka, Y.8
-
52
-
-
78650664775
-
Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells
-
Fenech M, Kirsch-Volders M, Natarajan AT, Surralles J, Crott JW, Parry J, Norppa H, Eastmond DA, Tucker JD, Thomas P. 2011. Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells. Mutagenesis 26:125-132.
-
(2011)
Mutagenesis
, vol.26
, pp. 125-132
-
-
Fenech, M.1
Kirsch-Volders, M.2
Natarajan, A.T.3
Surralles, J.4
Crott, J.W.5
Parry, J.6
Norppa, H.7
Eastmond, D.A.8
Tucker, J.D.9
Thomas, P.10
-
53
-
-
0027272082
-
Induction of micronuclei by HTLV-I Tax:a cellular assay for function
-
Majone F, Semmes OJ, Jeang KT. 1993. Induction of micronuclei by HTLV-I Tax:a cellular assay for function. Virology 193:456-459.
-
(1993)
Virology
, vol.193
, pp. 456-459
-
-
Majone, F.1
Semmes, O.J.2
Jeang, K.T.3
-
54
-
-
4344610852
-
Timing and checkpoints in the regulation of mitotic progression
-
Meraldi P, Draviam VM, Sorger PK. 2004. Timing and checkpoints in the regulation of mitotic progression. Dev. Cell 7:45-60.
-
(2004)
Dev. Cell
, vol.7
, pp. 45-60
-
-
Meraldi, P.1
Draviam, V.M.2
Sorger, P.K.3
-
55
-
-
79958733630
-
Mad2 is a critical mediator of the chromosome instability observed upon Rb and p53 pathway inhibition
-
Schvartzman JM, Duijf PH, Sotillo R, Coker C, Benezra R. 2011. Mad2 is a critical mediator of the chromosome instability observed upon Rb and p53 pathway inhibition. Cancer Cell 19:701-714.
-
(2011)
Cancer Cell
, vol.19
, pp. 701-714
-
-
Schvartzman, J.M.1
Duijf, P.H.2
Sotillo, R.3
Coker, C.4
Benezra, R.5
-
56
-
-
0021716296
-
In vitro mutagenesis of a putative DNA binding domain of SV40 large-T
-
Kalderon D, Smith AE. 1984. In vitro mutagenesis of a putative DNA binding domain of SV40 large-T. Virology 139:109-137.
-
(1984)
Virology
, vol.139
, pp. 109-137
-
-
Kalderon, D.1
Smith, A.E.2
-
57
-
-
34247333444
-
The spindle-assembly checkpoint in space and time
-
Musacchio A, Salmon ED. 2007. The spindle-assembly checkpoint in space and time. Nat. Rev. Mol. Cell Biol. 8:379-393.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 379-393
-
-
Musacchio, A.1
Salmon, E.D.2
-
58
-
-
13944261954
-
Human Bub1 defines the persistent cohesion site along the mitotic chromosome by affecting Shugoshin localization
-
Kitajima TS, Hauf S, Ohsugi M, Yamamoto T, Watanabe Y. 2005. Human Bub1 defines the persistent cohesion site along the mitotic chromosome by affecting Shugoshin localization. Curr. Biol. 15:353-359.
-
(2005)
Curr. Biol.
, vol.15
, pp. 353-359
-
-
Kitajima, T.S.1
Hauf, S.2
Ohsugi, M.3
Yamamoto, T.4
Watanabe, Y.5
-
59
-
-
77949579365
-
Mechanisms of chromosomal instability
-
doi:10.1016/j.cub.2010.01.034
-
Thompson SL, Bakhoum SF, Compton DA. 2010. Mechanisms of chromosomal instability. Curr. Biol. 20:R285-R295. doi:10.1016/j.cub.2010.01.034.
-
(2010)
Curr. Biol.
, vol.20
-
-
Thompson, S.L.1
Bakhoum, S.F.2
Compton, D.A.3
-
61
-
-
33644547006
-
Phosphorylated histone H2AX foci persist on rejoined mitotic chromosomes in normal human diploid cells exposed to ionizing radiation
-
Suzuki M, Suzuki K, Kodama S, Watanabe M. 2006. Phosphorylated histone H2AX foci persist on rejoined mitotic chromosomes in normal human diploid cells exposed to ionizing radiation. Radiat. Res. 165:269-276.
-
(2006)
Radiat. Res.
, vol.165
, pp. 269-276
-
-
Suzuki, M.1
Suzuki, K.2
Kodama, S.3
Watanabe, M.4
-
62
-
-
81955161162
-
New insights into the formation and resolution of ultra-fine anaphase bridges
-
Chan KL, Hickson ID. 2011. New insights into the formation and resolution of ultra-fine anaphase bridges. Semin. Cell Dev. Biol. 22:906-912.
-
(2011)
Semin. Cell Dev. Biol.
, vol.22
, pp. 906-912
-
-
Chan, K.L.1
Hickson, I.D.2
-
63
-
-
34547192058
-
BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges
-
Chan KL, North PS, Hickson ID. 2007. BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges. EMBO J. 26:3397-3409.
-
(2007)
EMBO J.
, vol.26
, pp. 3397-3409
-
-
Chan, K.L.1
North, P.S.2
Hickson, I.D.3
-
64
-
-
67349227137
-
Replication stress induces sister-chromatid bridging at fragile site loci in mitosis
-
Chan KL, Palmai-Pallag T, Ying S, Hickson ID. 2009. Replication stress induces sister-chromatid bridging at fragile site loci in mitosis. Nat. Cell Biol. 11:753-760.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 753-760
-
-
Chan, K.L.1
Palmai-Pallag, T.2
Ying, S.3
Hickson, I.D.4
-
65
-
-
79952281751
-
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress
-
Lukas C, Savic V, Bekker-Jensen S, Doil C, Neumann B, Pedersen RS, Grofte M, Chan KL, Hickson ID, Bartek J, Lukas J. 2011. 53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress. Nat. Cell Biol. 13:243-253.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 243-253
-
-
Lukas, C.1
Savic, V.2
Bekker-Jensen, S.3
Doil, C.4
Neumann, B.5
Pedersen, R.S.6
Grofte, M.7
Chan, K.L.8
Hickson, I.D.9
Bartek, J.10
Lukas, J.11
-
66
-
-
0029818753
-
Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen
-
Ewald D, Li M, Efrat S, Auer G, Wall RJ, Furth PA, Hennighausen L. 1996. Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen. Science 273:1384-1386.
-
(1996)
Science
, vol.273
, pp. 1384-1386
-
-
Ewald, D.1
Li, M.2
Efrat, S.3
Auer, G.4
Wall, R.J.5
Furth, P.A.6
Hennighausen, L.7
-
67
-
-
0023620257
-
Malignant progression of an SV40-transformed human epidermal keratinocyte cell line
-
Brown KW, Gallimore PH. 1987. Malignant progression of an SV40-transformed human epidermal keratinocyte cell line. Br. J. Cancer 56:545-554.
-
(1987)
Br. J. Cancer
, vol.56
, pp. 545-554
-
-
Brown, K.W.1
Gallimore, P.H.2
-
68
-
-
17244367849
-
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
-
Bartkova J, Horejsi Z, Koed K, Kramer A, Tort F, Zieger K, Guldberg P, Sehested M, Nesland JM, Lukas C, Orntoft T, Lukas J, Bartek J. 2005. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 434:864-870.
-
(2005)
Nature
, vol.434
, pp. 864-870
-
-
Bartkova, J.1
Horejsi, Z.2
Koed, K.3
Kramer, A.4
Tort, F.5
Zieger, K.6
Guldberg, P.7
Sehested, M.8
Nesland, J.M.9
Lukas, C.10
Orntoft, T.11
Lukas, J.12
Bartek, J.13
-
69
-
-
33845269825
-
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
-
Di Micco R, Fumagalli M, Cicalese A, Piccinin S, Gasparini P, Luise C, Schurra C, Garre M, Nuciforo PG, Bensimon A, Maestro R, Pelicci PG, d'Adda di Fagagna F. 2006. Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature 444:638-642.
-
(2006)
Nature
, vol.444
, pp. 638-642
-
-
Di Micco, R.1
Fumagalli, M.2
Cicalese, A.3
Piccinin, S.4
Gasparini, P.5
Luise, C.6
Schurra, C.7
Garre, M.8
Nuciforo, P.G.9
Bensimon, A.10
Maestro, R.11
Pelicci, P.G.12
d'Adda di Fagagna, F.13
-
70
-
-
80051772864
-
The relative efficiency of homologydirected repair has distinct effects on proper anaphase chromosome separation
-
Laulier C, Cheng A, Stark JM. 2011. The relative efficiency of homologydirected repair has distinct effects on proper anaphase chromosome separation. Nucleic Acids Res. 39:5935-5944.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 5935-5944
-
-
Laulier, C.1
Cheng, A.2
Stark, J.M.3
-
71
-
-
59049101302
-
Aurora B-mediated abscission checkpoint protects against tetraploidization
-
Steigemann P, Wurzenberger C, Schmitz MH, Held M, Guizetti J, Maar S, Gerlich DW. 2009. Aurora B-mediated abscission checkpoint protects against tetraploidization. Cell 136:473-484.
-
(2009)
Cell
, vol.136
, pp. 473-484
-
-
Steigemann, P.1
Wurzenberger, C.2
Schmitz, M.H.3
Held, M.4
Guizetti, J.5
Maar, S.6
Gerlich, D.W.7
-
72
-
-
77950932096
-
Persistent telomere damage induces bypass of mitosis and tetraploidy
-
Davoli T, Denchi EL, de Lange T. 2010. Persistent telomere damage induces bypass of mitosis and tetraploidy. Cell 141:81-93.
-
(2010)
Cell
, vol.141
, pp. 81-93
-
-
Davoli, T.1
Denchi, E.L.2
de Lange, T.3
-
73
-
-
84862127178
-
Telomere-driven tetraploidization occurs in human cells undergoing crisis and promotes transformation of mouse cells
-
Davoli T, de Lange T. 2012. Telomere-driven tetraploidization occurs in human cells undergoing crisis and promotes transformation of mouse cells. Cancer Cell 21:765-776.
-
(2012)
Cancer Cell
, vol.21
, pp. 765-776
-
-
Davoli, T.1
de Lange, T.2
-
74
-
-
27144507868
-
Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells
-
Fujiwara T, Bandi M, Nitta M, Ivanova EV, Bronson RT, Pellman D. 2005. Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells. Nature 437:1043-1047.
-
(2005)
Nature
, vol.437
, pp. 1043-1047
-
-
Fujiwara, T.1
Bandi, M.2
Nitta, M.3
Ivanova, E.V.4
Bronson, R.T.5
Pellman, D.6
-
76
-
-
67649467032
-
A mechanism linking extra centrosomes to chromosomal instability
-
Ganem NJ, Godinho SA, Pellman D. 2009. A mechanism linking extra centrosomes to chromosomal instability. Nature 460:278-282.
-
(2009)
Nature
, vol.460
, pp. 278-282
-
-
Ganem, N.J.1
Godinho, S.A.2
Pellman, D.3
-
77
-
-
0031931414
-
Characterization of the p53-dependent postmitotic checkpoint following spindle disruption
-
Lanni JS, Jacks T. 1998. Characterization of the p53-dependent postmitotic checkpoint following spindle disruption. Mol. Cell. Biol. 18:1055-1064.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 1055-1064
-
-
Lanni, J.S.1
Jacks, T.2
-
78
-
-
76349126361
-
Proliferation of aneuploid human cells is limited by a p53-dependent mechanism
-
Thompson SL, Compton DA. 2010. Proliferation of aneuploid human cells is limited by a p53-dependent mechanism. J. Cell Biol. 188:369-381.
-
(2010)
J. Cell Biol.
, vol.188
, pp. 369-381
-
-
Thompson, S.L.1
Compton, D.A.2
-
79
-
-
80052186209
-
p53:guardian of ploidy
-
Aylon Y, Oren M. 2011. p53:guardian of ploidy. Mol. Oncol. 5:315-323.
-
(2011)
Mol. Oncol.
, vol.5
, pp. 315-323
-
-
Aylon, Y.1
Oren, M.2
-
80
-
-
0026686753
-
Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53
-
Bargonetti J, Reynisdottir I, Friedman PN, Prives C. 1992. Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53. Genes Dev. 6:1886-1898.
-
(1992)
Genes Dev.
, vol.6
, pp. 1886-1898
-
-
Bargonetti, J.1
Reynisdottir, I.2
Friedman, P.N.3
Prives, C.4
-
81
-
-
33947731702
-
Bub1 is essential for assembly of the functional inner centromere
-
Boyarchuk Y, Salic A, Dasso M, Arnaoutov A. 2007. Bub1 is essential for assembly of the functional inner centromere. J. Cell Biol. 176:919-928.
-
(2007)
J. Cell Biol.
, vol.176
, pp. 919-928
-
-
Boyarchuk, Y.1
Salic, A.2
Dasso, M.3
Arnaoutov, A.4
-
82
-
-
0037195281
-
DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindleassembly checkpoint
-
Mikhailov A, Cole RW, Rieder CL. 2002. DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindleassembly checkpoint. Curr. Biol. 12:1797-1806.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1797-1806
-
-
Mikhailov, A.1
Cole, R.W.2
Rieder, C.L.3
-
83
-
-
84855854958
-
The kinetochore protein Bub1 participates in the DNA damage response
-
Yang C, Wang H, Xu Y, Brinkman KL, Ishiyama H, Wong ST, Xu B. 2011. The kinetochore protein Bub1 participates in the DNA damage response. DNA Repair (Amst.) 11:185-191.
-
(2011)
DNA Repair (Amst.)
, vol.11
, pp. 185-191
-
-
Yang, C.1
Wang, H.2
Xu, Y.3
Brinkman, K.L.4
Ishiyama, H.5
Wong, S.T.6
Xu, B.7
-
84
-
-
81355164085
-
Aurora-B mediated ATM serine 1403 phosphorylation is required for mitoticATMactivation and the spindle checkpoint
-
Yang C, Tang X, Guo X, Niikura Y, Kitagawa K, Cui K, Wong ST, Fu L, Xu B. 2011. Aurora-B mediated ATM serine 1403 phosphorylation is required for mitoticATMactivation and the spindle checkpoint. Mol. Cell 44:597-608.
-
(2011)
Mol. Cell
, vol.44
, pp. 597-608
-
-
Yang, C.1
Tang, X.2
Guo, X.3
Niikura, Y.4
Kitagawa, K.5
Cui, K.6
Wong, S.T.7
Fu, L.8
Xu, B.9
-
86
-
-
84866162476
-
Roles of ATM and ATR-mediated DNA damage responses during lytic BK polyomavirus infection
-
doi:10.1371/journal.ppat.1002898
-
Jiang M, Zhao L, Gamez M, Imperiale MJ. 2012. Roles of ATM and ATR-mediated DNA damage responses during lytic BK polyomavirus infection. PLoS Pathog. 8:e1002898. doi:10.1371/journal.ppat.1002898.
-
(2012)
PLoS Pathog.
, vol.8
-
-
Jiang, M.1
Zhao, L.2
Gamez, M.3
Imperiale, M.J.4
-
87
-
-
79958865837
-
A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations
-
Toledo LI, Murga M, Zur R, Soria R, Rodriguez A, Martinez S, Oyarzabal J, Pastor J, Bischoff JR, Fernandez-Capetillo O. 2011. A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations. Nat. Struct. Mol. Biol. 18:721-727.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 721-727
-
-
Toledo, L.I.1
Murga, M.2
Zur, R.3
Soria, R.4
Rodriguez, A.5
Martinez, S.6
Oyarzabal, J.7
Pastor, J.8
Bischoff, J.R.9
Fernandez-Capetillo, O.10
-
88
-
-
80052298198
-
The papillomavirus E1 helicase activates a cellular DNA damage response in viral replication foci
-
Sakakibara N, Mitra R, McBride AA. 2011. The papillomavirus E1 helicase activates a cellular DNA damage response in viral replication foci. J. Virol. 85:8981-8995.
-
(2011)
J. Virol.
, vol.85
, pp. 8981-8995
-
-
Sakakibara, N.1
Mitra, R.2
McBride, A.A.3
-
89
-
-
80052275777
-
Nuclear accumulation of the papillomavirus E1 helicase blocks S-phase progression and triggers an ATMdependent DNA damage response
-
Fradet-Turcotte A, Bergeron-Labrecque F, Moody CA, Lehoux M, Laimins LA, Archambault J. 2011. Nuclear accumulation of the papillomavirus E1 helicase blocks S-phase progression and triggers an ATMdependent DNA damage response. J. Virol. 85:8996-9012.
-
(2011)
J. Virol.
, vol.85
, pp. 8996-9012
-
-
Fradet-Turcotte, A.1
Bergeron-Labrecque, F.2
Moody, C.A.3
Lehoux, M.4
Laimins, L.A.5
Archambault, J.6
-
90
-
-
79952233635
-
Chromosomal instability confers intrinsic multidrug resistance
-
Lee AJ, Endesfelder D, Rowan AJ, Walther A, Birkbak NJ, Futreal PA, Downward J, Szallasi Z, Tomlinson IP, Howell M, Kschischo M, Swanton C. 2011. Chromosomal instability confers intrinsic multidrug resistance. Cancer Res. 71:1858-1870.
-
(2011)
Cancer Res.
, vol.71
, pp. 1858-1870
-
-
Lee, A.J.1
Endesfelder, D.2
Rowan, A.J.3
Walther, A.4
Birkbak, N.J.5
Futreal, P.A.6
Downward, J.7
Szallasi, Z.8
Tomlinson, I.P.9
Howell, M.10
Kschischo, M.11
Swanton, C.12
-
91
-
-
0036897282
-
The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability
-
Duensing S, Munger K. 2002. The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability. Cancer Res. 62:7075-7082.
-
(2002)
Cancer Res.
, vol.62
, pp. 7075-7082
-
-
Duensing, S.1
Munger, K.2
-
92
-
-
36349032360
-
The human papillomavirus type 16 E7 oncoprotein activates the Fanconi anemia (FA) pathway and causes accelerated chromosomal instability in FA cells
-
Spardy N, Duensing A, Charles D, Haines N, Nakahara T, Lambert PF, Duensing S. 2007. The human papillomavirus type 16 E7 oncoprotein activates the Fanconi anemia (FA) pathway and causes accelerated chromosomal instability in FA cells. J. Virol. 81:13265-13270.
-
(2007)
J. Virol.
, vol.81
, pp. 13265-13270
-
-
Spardy, N.1
Duensing, A.2
Charles, D.3
Haines, N.4
Nakahara, T.5
Lambert, P.F.6
Duensing, S.7
-
93
-
-
33750284306
-
Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo
-
Zimmerman ES, Sherman MP, Blackett JL, Neidleman JA, Kreis C, Mundt P, Williams SA, Warmerdam M, Kahn J, Hecht FM, Grant RM, de Noronha CM, Weyrich AS, Greene WC, Planelles V. 2006. Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo. J. Virol. 80:10407-10418.
-
(2006)
J. Virol.
, vol.80
, pp. 10407-10418
-
-
Zimmerman, E.S.1
Sherman, M.P.2
Blackett, J.L.3
Neidleman, J.A.4
Kreis, C.5
Mundt, P.6
Williams, S.A.7
Warmerdam, M.8
Kahn, J.9
Hecht, F.M.10
Grant, R.M.11
de Noronha, C.M.12
Weyrich, A.S.13
Greene, W.C.14
Planelles, V.15
-
94
-
-
0033563004
-
Micronuclei formation with chromosome breaks and gene amplification caused by Vpr, an accessory gene of human immunodeficiency virus
-
Shimura M, Onozuka Y, Yamaguchi T, Hatake K, Takaku F, Ishizaka Y. 1999. Micronuclei formation with chromosome breaks and gene amplification caused by Vpr, an accessory gene of human immunodeficiency virus. Cancer Res. 59:2259-2264.
-
(1999)
Cancer Res.
, vol.59
, pp. 2259-2264
-
-
Shimura, M.1
Onozuka, Y.2
Yamaguchi, T.3
Hatake, K.4
Takaku, F.5
Ishizaka, Y.6
|