메뉴 건너뛰기




Volumn 21, Issue 6, 2012, Pages 765-776

Telomere-Driven Tetraploidization Occurs in Human Cells Undergoing Crisis and Promotes Transformation of Mouse Cells

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PROTEIN P53; RETINOBLASTOMA PROTEIN;

EID: 84862127178     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccr.2012.03.044     Document Type: Article
Times cited : (180)

References (48)
  • 1
    • 11844273174 scopus 로고    scopus 로고
    • Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts
    • Arias E.E., Walter J.C. Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts. Genes Dev. 2005, 19:114-126.
    • (2005) Genes Dev. , vol.19 , pp. 114-126
    • Arias, E.E.1    Walter, J.C.2
  • 2
    • 74049111326 scopus 로고    scopus 로고
    • Telomeres and telomerase in cancer
    • Artandi S.E., DePinho R.A. Telomeres and telomerase in cancer. Carcinogenesis 2010, 31:9-18.
    • (2010) Carcinogenesis , vol.31 , pp. 9-18
    • Artandi, S.E.1    DePinho, R.A.2
  • 3
    • 0034632717 scopus 로고    scopus 로고
    • Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
    • Artandi S.E., Chang S., Lee S.L., Alson S., Gottlieb G.J., Chin L., DePinho R.A. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature 2000, 406:641-645.
    • (2000) Nature , vol.406 , pp. 641-645
    • Artandi, S.E.1    Chang, S.2    Lee, S.L.3    Alson, S.4    Gottlieb, G.J.5    Chin, L.6    DePinho, R.A.7
  • 5
    • 22144490491 scopus 로고    scopus 로고
    • DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion
    • Celli G.B., de Lange T. DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion. Nat. Cell Biol. 2005, 7:712-718.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 712-718
    • Celli, G.B.1    de Lange, T.2
  • 7
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
    • Counter C.M., Avilion A.A., LeFeuvre C.E., Stewart N.G., Greider C.W., Harley C.B., Bacchetti S. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 1992, 11:1921-1929.
    • (1992) EMBO J. , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avilion, A.A.2    LeFeuvre, C.E.3    Stewart, N.G.4    Greider, C.W.5    Harley, C.B.6    Bacchetti, S.7
  • 9
    • 80054029091 scopus 로고    scopus 로고
    • The causes and consequences of polyploidy in normal development and cancer
    • Davoli T., de Lange T. The causes and consequences of polyploidy in normal development and cancer. Annu. Rev. Cell Dev. Biol. 2011, 27:22.1-22.26.
    • (2011) Annu. Rev. Cell Dev. Biol. , vol.27
    • Davoli, T.1    de Lange, T.2
  • 10
    • 77950932096 scopus 로고    scopus 로고
    • Persistent telomere damage induces bypass of mitosis and tetraploidy
    • Davoli T., Denchi E.L., de Lange T. Persistent telomere damage induces bypass of mitosis and tetraploidy. Cell 2010, 141:81-93.
    • (2010) Cell , vol.141 , pp. 81-93
    • Davoli, T.1    Denchi, E.L.2    de Lange, T.3
  • 11
    • 33746425690 scopus 로고    scopus 로고
    • Telomere-related genome instability in cancer
    • de Lange T. Telomere-related genome instability in cancer. Cold Spring Harb. Symp. Quant. Biol. 2005, 70:197-204.
    • (2005) Cold Spring Harb. Symp. Quant. Biol. , vol.70 , pp. 197-204
    • de Lange, T.1
  • 14
    • 27144507868 scopus 로고    scopus 로고
    • Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells
    • Fujiwara T., Bandi M., Nitta M., Ivanova E.V., Bronson R.T., Pellman D. Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells. Nature 2005, 437:1043-1047.
    • (2005) Nature , vol.437 , pp. 1043-1047
    • Fujiwara, T.1    Bandi, M.2    Nitta, M.3    Ivanova, E.V.4    Bronson, R.T.5    Pellman, D.6
  • 16
    • 34548288604 scopus 로고    scopus 로고
    • Inactivation of p53 function in cultured human mammary epithelial cells turns the telomere-length dependent senescence barrier from agonescence into crisis
    • Garbe J.C., Holst C.R., Bassett E., Tlsty T., Stampfer M.R. Inactivation of p53 function in cultured human mammary epithelial cells turns the telomere-length dependent senescence barrier from agonescence into crisis. Cell Cycle 2007, 6:1927-1936.
    • (2007) Cell Cycle , vol.6 , pp. 1927-1936
    • Garbe, J.C.1    Holst, C.R.2    Bassett, E.3    Tlsty, T.4    Stampfer, M.R.5
  • 17
    • 36749022214 scopus 로고    scopus 로고
    • The DNA damage response: ten years after
    • Harper J.W., Elledge S.J. The DNA damage response: ten years after. Mol. Cell 2007, 28:739-745.
    • (2007) Mol. Cell , vol.28 , pp. 739-745
    • Harper, J.W.1    Elledge, S.J.2
  • 19
    • 2442511752 scopus 로고    scopus 로고
    • Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)
    • Herbig U., Jobling W.A., Chen B.P., Chen D.J., Sedivy J.M. Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Mol. Cell 2004, 14:501-513.
    • (2004) Mol. Cell , vol.14 , pp. 501-513
    • Herbig, U.1    Jobling, W.A.2    Chen, B.P.3    Chen, D.J.4    Sedivy, J.M.5
  • 20
    • 33745685066 scopus 로고    scopus 로고
    • Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres
    • Hockemeyer D., Daniels J.P., Takai H., de Lange T. Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres. Cell 2006, 126:63-77.
    • (2006) Cell , vol.126 , pp. 63-77
    • Hockemeyer, D.1    Daniels, J.P.2    Takai, H.3    de Lange, T.4
  • 21
    • 11144268164 scopus 로고    scopus 로고
    • Significant role for p16INK4a in p53-independent telomere-directed senescence
    • Jacobs J.J., de Lange T. Significant role for p16INK4a in p53-independent telomere-directed senescence. Curr. Biol. 2004, 14:2302-2308.
    • (2004) Curr. Biol. , vol.14 , pp. 2302-2308
    • Jacobs, J.J.1    de Lange, T.2
  • 22
    • 0037192462 scopus 로고    scopus 로고
    • Senescence induced by altered telomere state, not telomere loss
    • Karlseder J., Smogorzewska A., de Lange T. Senescence induced by altered telomere state, not telomere loss. Science 2002, 295:2446-2449.
    • (2002) Science , vol.295 , pp. 2446-2449
    • Karlseder, J.1    Smogorzewska, A.2    de Lange, T.3
  • 23
    • 75749092997 scopus 로고    scopus 로고
    • Telomere protection by TPP1 is mediated by POT1a and POT1b
    • Kibe T., Osawa G.A., Keegan C.E., de Lange T. Telomere protection by TPP1 is mediated by POT1a and POT1b. Mol. Cell. Biol. 2010, 30:1059-1066.
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 1059-1066
    • Kibe, T.1    Osawa, G.A.2    Keegan, C.E.3    de Lange, T.4
  • 25
    • 0014154512 scopus 로고
    • Comparative study of histologic and chromosomal abnormalities in cervical neoplasia
    • Kirkland J.A., Stanley M.A., Cellier K.M. Comparative study of histologic and chromosomal abnormalities in cervical neoplasia. Cancer 1967, 20:1934-1952.
    • (1967) Cancer , vol.20 , pp. 1934-1952
    • Kirkland, J.A.1    Stanley, M.A.2    Cellier, K.M.3
  • 26
    • 0031004175 scopus 로고    scopus 로고
    • Genetic instability in colorectal cancers
    • Lengauer C., Kinzler K.W., Vogelstein B. Genetic instability in colorectal cancers. Nature 1997, 386:623-627.
    • (1997) Nature , vol.386 , pp. 623-627
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 27
    • 77956945086 scopus 로고    scopus 로고
    • Telomere dysfunction and fusion during the progression of chronic lymphocytic leukemia: evidence for a telomere crisis
    • Lin T.T., Letsolo B.T., Jones R.E., Rowson J., Pratt G., Hewamana S., Fegan C., Pepper C., Baird D.M. Telomere dysfunction and fusion during the progression of chronic lymphocytic leukemia: evidence for a telomere crisis. Blood 2010, 116:1899-1907.
    • (2010) Blood , vol.116 , pp. 1899-1907
    • Lin, T.T.1    Letsolo, B.T.2    Jones, R.E.3    Rowson, J.4    Pratt, G.5    Hewamana, S.6    Fegan, C.7    Pepper, C.8    Baird, D.M.9
  • 28
    • 0037373258 scopus 로고    scopus 로고
    • G1 tetraploidy checkpoint and the suppression of tumorigenesis
    • Margolis R.L., Lohez O.D., Andreassen P.R. G1 tetraploidy checkpoint and the suppression of tumorigenesis. J. Cell. Biochem. 2003, 88:673-683.
    • (2003) J. Cell. Biochem. , vol.88 , pp. 673-683
    • Margolis, R.L.1    Lohez, O.D.2    Andreassen, P.R.3
  • 29
    • 9244244706 scopus 로고    scopus 로고
    • Telomere shortening occurs early during breast tumorigenesis: a cause of chromosome destabilization underlying malignant transformation?
    • Meeker A.K., Argani P. Telomere shortening occurs early during breast tumorigenesis: a cause of chromosome destabilization underlying malignant transformation?. J. Mammary Gland Biol. Neoplasia 2004, 9:285-296.
    • (2004) J. Mammary Gland Biol. Neoplasia , vol.9 , pp. 285-296
    • Meeker, A.K.1    Argani, P.2
  • 33
    • 0038678062 scopus 로고    scopus 로고
    • Carcinoma in situ of the female breast. A clinico-pathological, immunohistological, and DNA ploidy study
    • Ottesen G.L. Carcinoma in situ of the female breast. A clinico-pathological, immunohistological, and DNA ploidy study. APMIS Suppl. 2003, 108:1-67.
    • (2003) APMIS Suppl. , vol.108 , pp. 1-67
    • Ottesen, G.L.1
  • 35
    • 70549085855 scopus 로고    scopus 로고
    • Eukaryotic DNA replication control: lock and load, then fire
    • Remus D., Diffley J.F. Eukaryotic DNA replication control: lock and load, then fire. Curr. Opin. Cell Biol. 2009, 21:771-777.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 771-777
    • Remus, D.1    Diffley, J.F.2
  • 36
    • 0035252089 scopus 로고    scopus 로고
    • Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes
    • Romanov S.R., Kozakiewicz B.K., Holst C.R., Stampfer M.R., Haupt L.M., Tlsty T.D. Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes. Nature 2001, 409:633-637.
    • (2001) Nature , vol.409 , pp. 633-637
    • Romanov, S.R.1    Kozakiewicz, B.K.2    Holst, C.R.3    Stampfer, M.R.4    Haupt, L.M.5    Tlsty, T.D.6
  • 38
    • 2142658985 scopus 로고    scopus 로고
    • Molecular evolutionary patterns in breast cancer
    • Shackney S.E., Silverman J.F. Molecular evolutionary patterns in breast cancer. Adv. Anat. Pathol. 2003, 10:278-290.
    • (2003) Adv. Anat. Pathol. , vol.10 , pp. 278-290
    • Shackney, S.E.1    Silverman, J.F.2
  • 40
    • 0031010342 scopus 로고    scopus 로고
    • A survey of telomerase activity in human cancer
    • Shay J.W., Bacchetti S. A survey of telomerase activity in human cancer. Eur. J. Cancer 1997, 33:787-791.
    • (1997) Eur. J. Cancer , vol.33 , pp. 787-791
    • Shay, J.W.1    Bacchetti, S.2
  • 41
    • 19844382620 scopus 로고    scopus 로고
    • Senescence and immortalization: role of telomeres and telomerase
    • Shay J.W., Wright W.E. Senescence and immortalization: role of telomeres and telomerase. Carcinogenesis 2005, 26:867-874.
    • (2005) Carcinogenesis , vol.26 , pp. 867-874
    • Shay, J.W.1    Wright, W.E.2
  • 42
    • 0026054961 scopus 로고
    • A role for both RB and p53 in the regulation of human cellular senescence
    • Shay J.W., Pereira-Smith O.M., Wright W.E. A role for both RB and p53 in the regulation of human cellular senescence. Exp. Cell Res. 1991, 196:33-39.
    • (1991) Exp. Cell Res. , vol.196 , pp. 33-39
    • Shay, J.W.1    Pereira-Smith, O.M.2    Wright, W.E.3
  • 43
    • 0027496456 scopus 로고
    • The frequency of immortalization of human fibroblasts and mammary epithelial cells transfected with SV40 large T-antigen
    • Shay J.W., Van Der Haegen B.A., Ying Y., Wright W.E. The frequency of immortalization of human fibroblasts and mammary epithelial cells transfected with SV40 large T-antigen. Exp. Cell Res. 1993, 209:45-52.
    • (1993) Exp. Cell Res. , vol.209 , pp. 45-52
    • Shay, J.W.1    Van Der Haegen, B.A.2    Ying, Y.3    Wright, W.E.4
  • 44
    • 0037102234 scopus 로고    scopus 로고
    • Different telomere damage signaling pathways in human and mouse cells
    • Smogorzewska A., de Lange T. Different telomere damage signaling pathways in human and mouse cells. EMBO J. 2002, 21:4338-4348.
    • (2002) EMBO J. , vol.21 , pp. 4338-4348
    • Smogorzewska, A.1    de Lange, T.2
  • 46
    • 59349098193 scopus 로고    scopus 로고
    • The consequences of tetraploidy and aneuploidy
    • Storchova Z., Kuffer C. The consequences of tetraploidy and aneuploidy. J. Cell Sci. 2008, 121:3859-3866.
    • (2008) J. Cell Sci. , vol.121 , pp. 3859-3866
    • Storchova, Z.1    Kuffer, C.2
  • 48
    • 0026680249 scopus 로고
    • The two-stage mechanism controlling cellular senescence and immortalization
    • Wright W.E., Shay J.W. The two-stage mechanism controlling cellular senescence and immortalization. Exp. Gerontol. 1992, 27:383-389.
    • (1992) Exp. Gerontol. , vol.27 , pp. 383-389
    • Wright, W.E.1    Shay, J.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.