메뉴 건너뛰기




Volumn 13, Issue 6, 1999, Pages 621-637

Micronuclei formation and aneuploidy induced by Vpr, an accessory gene of human immunodeficiency virus type 1

Author keywords

Genomic instability; HIV 1 Vpr; Multinucleation

Indexed keywords

CYTOCHALASIN B; DIMETHYL SULFOXIDE; DOXYCYCLINE; MESSENGER RNA; MONOCLONAL ANTIBODY; NOCODAZOLE;

EID: 0032919559     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.13.6.621     Document Type: Article
Times cited : (44)

References (71)
  • 1
    • 0025295307 scopus 로고
    • Human immunodeficiency virus vpr product is a virion-associated regulatory protein
    • Cohen, E. A., Dehni, G., Sodroski, J. G., and Haseltine, W. A. (1990) Human immunodeficiency virus vpr product is a virion-associated regulatory protein. J. Virol. 64, 3097-3099
    • (1990) J. Virol. , vol.64 , pp. 3097-3099
    • Cohen, E.A.1    Dehni, G.2    Sodroski, J.G.3    Haseltine, W.A.4
  • 2
  • 3
    • 0027429412 scopus 로고
    • Incorporation of Vpr into human immunodeficiency virus type 1 virions: Requirement for the p6 region of gag and mutational analysis
    • Paxton, W., Connor, R. I., and Landau, N. R. (1993) Incorporation of Vpr into human immunodeficiency virus type 1 virions: requirement for the p6 region of gag and mutational analysis. J. Virol. 67, 7229-7237
    • (1993) J. Virol. , vol.67 , pp. 7229-7237
    • Paxton, W.1    Connor, R.I.2    Landau, N.R.3
  • 5
    • 0024990404 scopus 로고
    • Open reading frame vpr of simian immunodeficiency virus encodes a virion-associated protein
    • Yu, X.-F., Matsuda, M., Essex, M., and Lee, T.-H. (1990) Open reading frame vpr of simian immunodeficiency virus encodes a virion-associated protein. J. Virol. 64, 5688-5693
    • (1990) J. Virol. , vol.64 , pp. 5688-5693
    • Yu, X.-F.1    Matsuda, M.2    Essex, M.3    Lee, T.-H.4
  • 6
    • 0025017950 scopus 로고
    • The human immunodeficiency virus type 2 vpr gene is essential for productive infection of human macrophages
    • Hattori, N., Michaels, F., Fargnoli, K., Marcon, L., Gallo, R. C., and Franchini, G. (1990) The human immunodeficiency virus type 2 vpr gene is essential for productive infection of human macrophages. Proc. Natl. Acad. Sci. USA 87, 8080-8084
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8080-8084
    • Hattori, N.1    Michaels, F.2    Fargnoli, K.3    Marcon, L.4    Gallo, R.C.5    Franchini, G.6
  • 7
    • 0026655258 scopus 로고
    • Dual regulation of silent and productive infection in monocytes by distinct human immunodeficiency virus type 1 determinants
    • Westervelt, P., Henkel, T., Trowbridge, D. B., Orenstein, J., Heuser, J., Gendelman, H. E., and Ratner, L. (1992) Dual regulation of silent and productive infection in monocytes by distinct human immunodeficiency virus type 1 determinants. J. Virol. 66, 3925-3931
    • (1992) J. Virol. , vol.66 , pp. 3925-3931
    • Westervelt, P.1    Henkel, T.2    Trowbridge, D.B.3    Orenstein, J.4    Heuser, J.5    Gendelman, H.E.6    Ratner, L.7
  • 8
    • 0030250588 scopus 로고    scopus 로고
    • HIV-1, Vpr and the cell cycle
    • Emerman, M. (1996) HIV-1, Vpr and the cell cycle. Curr. Biol. 6, 1096-1103
    • (1996) Curr. Biol. , vol.6 , pp. 1096-1103
    • Emerman, M.1
  • 9
    • 0029869861 scopus 로고    scopus 로고
    • Vpr-induced cell cycle arrest is conserved among primate lentiviruses
    • Planelles, V., Jowett, J. B. M., Li, Q.-X., Xie, Y., Hahn, B., and Chen, I. S. Y. (1996) Vpr-induced cell cycle arrest is conserved among primate lentiviruses. J. Virol. 70, 2516-2524
    • (1996) J. Virol. , vol.70 , pp. 2516-2524
    • Planelles, V.1    Jowett, J.B.M.2    Li, Q.-X.3    Xie, Y.4    Hahn, B.5    Chen, I.S.Y.6
  • 12
    • 0028824894 scopus 로고
    • Mutational analysis of cell cycle arrest, nuclear localization, and virion packaging of human immunodeficiency virus type 1 Vpr
    • Marzio, P. D., Choe, S., Ebright, M., Knoblauch, R., and Landau, N. R. (1995) Mutational analysis of cell cycle arrest, nuclear localization, and virion packaging of human immunodeficiency virus type 1 Vpr. J. Virol. 69, 7909-7916
    • (1995) J. Virol. , vol.69 , pp. 7909-7916
    • Marzio, P.D.1    Choe, S.2    Ebright, M.3    Knoblauch, R.4    Landau, N.R.5
  • 13
    • 0029993519 scopus 로고    scopus 로고
    • 2 accumulation by a mechanism which differs from DNA damage checkpoint control
    • 2 accumulation by a mechanism which differs from DNA damage checkpoint control. J. Virol. 70, 2324-2331
    • (1996) J. Virol. , vol.70 , pp. 2324-2331
    • Bartz, S.R.1    Rogel, M.E.2    Emerman, M.3
  • 14
    • 0030795827 scopus 로고    scopus 로고
    • HIV-1 protein Vpr causes gross mitochondrial dysfunction in the yeast Saccharomyces cerevisiae
    • Macreadie, I. G., Thorburn, D. R., Kirby, D. M., Castelli, L. A., de Rozario, N. L., and Azad, A. A. (1997) HIV-1 protein Vpr causes gross mitochondrial dysfunction in the yeast Saccharomyces cerevisiae. FEBS Lett. 410, 145-149
    • (1997) FEBS Lett. , vol.410 , pp. 145-149
    • Macreadie, I.G.1    Thorburn, D.R.2    Kirby, D.M.3    Castelli, L.A.4    De Rozario, N.L.5    Azad, A.A.6
  • 15
    • 0031592602 scopus 로고    scopus 로고
    • Cell cycle inhibitory effects of HIV and SIV Vpr and Vpx in the yeast Schizosaccharomyces pombe
    • Zhang, C., Rasmussen, C., and Chang, L.-J. (1997) Cell cycle inhibitory effects of HIV and SIV Vpr and Vpx in the yeast Schizosaccharomyces pombe. Virology 230, 103-112
    • (1997) Virology , vol.230 , pp. 103-112
    • Zhang, C.1    Rasmussen, C.2    Chang, L.-J.3
  • 18
    • 0003124066 scopus 로고    scopus 로고
    • HIV-1 Vpr increases viral expression by manipulation of the cell cycle: A mechanism for selection of Vpr in vivo
    • Goh, W. C., Rogel, M. E., Kinsey, C. M., Michael, S. F., Fultz, P. N., Nowak, M. A., Hahn, B. H., and Emerman, M. (1998) HIV-1 Vpr increases viral expression by manipulation of the cell cycle: a mechanism for selection of Vpr in vivo. Nat. Med. 4, 65-71
    • (1998) Nat. Med. , vol.4 , pp. 65-71
    • Goh, W.C.1    Rogel, M.E.2    Kinsey, C.M.3    Michael, S.F.4    Fultz, P.N.5    Nowak, M.A.6    Hahn, B.H.7    Emerman, M.8
  • 20
    • 0028568315 scopus 로고
    • Cell cycle control and cancer
    • Hartwell, L.H., and Kastan, M.B. (1994) Cell cycle control and cancer. Science 266, 1821-1828
    • (1994) Science , vol.266 , pp. 1821-1828
    • Hartwell, L.H.1    Kastan, M.B.2
  • 21
  • 22
    • 0026801062 scopus 로고
    • Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
    • Livingstone, L. R., White, A., Sprouse, J., Livanos, E., Jacks, T., and Tlsty, T. D. (1992) Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 70, 923-935
    • (1992) Cell , vol.70 , pp. 923-935
    • Livingstone, L.R.1    White, A.2    Sprouse, J.3    Livanos, E.4    Jacks, T.5    Tlsty, T.D.6
  • 23
    • 0026801977 scopus 로고
    • Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
    • Yin, Y., Tainsky, M. A., Bischoff, F. Z., Strong, L. C., and Wahl, G. M. (1992) Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 70, 937-948
    • (1992) Cell , vol.70 , pp. 937-948
    • Yin, Y.1    Tainsky, M.A.2    Bischoff, F.Z.3    Strong, L.C.4    Wahl, G.M.5
  • 24
    • 0028938734 scopus 로고
    • p53-dependent growth arrest of REF52 cells containing newly amplified DNA
    • Ishizaka, Y., Chernov, M. V., Burns, C. M., and Stark, G. R. (1995) p53-dependent growth arrest of REF52 cells containing newly amplified DNA. Proc. Natl. Acad. Sci. USA 92, 3224-3228
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3224-3228
    • Ishizaka, Y.1    Chernov, M.V.2    Burns, C.M.3    Stark, G.R.4
  • 25
    • 0032574788 scopus 로고    scopus 로고
    • An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control
    • Gualberto, A., Aldape, K., Kozakiewicz, K., and Tlsty, T. D. (1998) An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control. Proc. Natl. Acad. Sci. USA 95, 5166-5171
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5166-5171
    • Gualberto, A.1    Aldape, K.2    Kozakiewicz, K.3    Tlsty, T.D.4
  • 26
    • 0032478547 scopus 로고    scopus 로고
    • Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1
    • Jin, D.-Y., Spencer, F., and Jeang, K.-T. (1998) Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1. Cell 93, 81-91
    • (1998) Cell , vol.93 , pp. 81-91
    • Jin, D.-Y.1    Spencer, F.2    Jeang, K.-T.3
  • 27
    • 0032539548 scopus 로고    scopus 로고
    • Cell cycle-dependent subcellular localization of the TSG101 protein and mitotic and nuclear abnormalities associated with TSG101 deficiency
    • Xie, W., Li, L., and Cohen, S. N., (1998) Cell cycle-dependent subcellular localization of the TSG101 protein and mitotic and nuclear abnormalities associated with TSG101 deficiency. Proc. Natl. Acad. Sci. USA 95, 1595-1600
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 1595-1600
    • Xie, W.1    Li, L.2    Cohen, S.N.3
  • 28
    • 0030687987 scopus 로고    scopus 로고
    • Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage
    • Taylor, S. S., and Mckeon, F. (1997) Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage. Cell 89, 727-735
    • (1997) Cell , vol.89 , pp. 727-735
    • Taylor, S.S.1    Mckeon, F.2
  • 30
    • 0025908226 scopus 로고
    • AIDS-associated non-Hodgkin lymphoma
    • Beral, V., Peterman, T., Berkelman, R., and Jaffe, H. (1991) AIDS-associated non-Hodgkin lymphoma. Lancet 337, 805-809
    • (1991) Lancet , vol.337 , pp. 805-809
    • Beral, V.1    Peterman, T.2    Berkelman, R.3    Jaffe, H.4
  • 31
    • 0030512218 scopus 로고    scopus 로고
    • Kaposi's sarcoma and non-Hodgkin's lymphoma following the diagnosis of AIDS
    • Biggar, R. J., Rosenberg, P. S., Coté, T., and the Multistate AIDS/Cancer Match Study Group (1996) Kaposi's sarcoma and non-Hodgkin's lymphoma following the diagnosis of AIDS. Int. J. Cancer 68, 754-758
    • (1996) Int. J. Cancer , vol.68 , pp. 754-758
    • Biggar, R.J.1    Rosenberg, P.S.2    Coté, T.3
  • 32
    • 0018192810 scopus 로고
    • Malignancies associated with immunosuppressive or cytotoxic therapy
    • Penn, I. (1978) Malignancies associated with immunosuppressive or cytotoxic therapy. Surgery 83, 492-502
    • (1978) Surgery , vol.83 , pp. 492-502
    • Penn, I.1
  • 33
    • 0018169706 scopus 로고
    • Genetically determined immunodeficiency disease (GDID) and malignancy: Report from the immunodeficiency cancer registry
    • Spector, B. D., Perry, G. S., and Kersey, J. H. (1978) Genetically determined immunodeficiency disease (GDID) and malignancy: report from the immunodeficiency cancer registry. Clin. Immunol. Immunopathol. 11, 12-29
    • (1978) Clin. Immunol. Immunopathol. , vol.11 , pp. 12-29
    • Spector, B.D.1    Perry, G.S.2    Kersey, J.H.3
  • 35
    • 0029319278 scopus 로고
    • Carcinogenic potential of human immunodeficiency virus (HFV): Emerging evidence
    • Mayer, V., Ebbesen, P., and Zachar, V. (1995) Carcinogenic potential of human immunodeficiency virus (HFV): emerging evidence. Eur. J. Cancer Prev. 4, 211-212
    • (1995) Eur. J. Cancer Prev. , vol.4 , pp. 211-212
    • Mayer, V.1    Ebbesen, P.2    Zachar, V.3
  • 36
    • 0025867199 scopus 로고
    • Human immunodeficiency virus induction of malignant transformation in human B lymphocytes
    • Laurence, J., and Astrin S. M. (1991) Human immunodeficiency virus induction of malignant transformation in human B lymphocytes. Proc. Natl. Acad. Sci. USA 88, 7635-7639
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 7635-7639
    • Laurence, J.1    Astrin, S.M.2
  • 37
    • 0015623107 scopus 로고
    • A rapid in vivo test for chromosomal damage
    • Heddle, J. A. (1973) A rapid in vivo test for chromosomal damage. Mutat. Res. 18, 187-190
    • (1973) Mutat. Res. , vol.18 , pp. 187-190
    • Heddle, J.A.1
  • 38
    • 0016437314 scopus 로고
    • The micronucleus test
    • Schmid, W. (1975) The micronucleus test. Mutat. Res. 31, 9-15
    • (1975) Mutat. Res. , vol.31 , pp. 9-15
    • Schmid, W.1
  • 39
    • 0024350940 scopus 로고
    • Kinetochore localization in micronucleated cytokinesis-blocked Chinese hamster ovary cells: A new and rapid assay for identifying aneuploidy-inducing agents
    • Eastmond, D. A., and Tucker, J. D. (1989) Kinetochore localization in micronucleated cytokinesis-blocked Chinese hamster ovary cells: a new and rapid assay for identifying aneuploidy-inducing agents. Mutat. Res. 224, 517-525
    • (1989) Mutat. Res. , vol.224 , pp. 517-525
    • Eastmond, D.A.1    Tucker, J.D.2
  • 40
    • 0024461337 scopus 로고
    • Identification of aneuploidy-inducing agents using cytokinesis-blocked human lymphocytes and an antikinetochore antibody
    • Eastmond, D. A., and Tucker, J. D. (1989) Identification of aneuploidy-inducing agents using cytokinesis-blocked human lymphocytes and an antikinetochore antibody. Environ. Mol. Mutagen. 13, 34-43
    • (1989) Environ. Mol. Mutagen. , vol.13 , pp. 34-43
    • Eastmond, D.A.1    Tucker, J.D.2
  • 41
  • 42
    • 0028318421 scopus 로고
    • Biochemical mechanism of HIV-I Vpr function
    • Zhao, L.-J., Mukherjee, S., and Narayan, O. (1994) Biochemical mechanism of HIV-I Vpr function. J. Biol. Chem. 269, 15577-15582
    • (1994) J. Biol. Chem. , vol.269 , pp. 15577-15582
    • Zhao, L.-J.1    Mukherjee, S.2    Narayan, O.3
  • 43
    • 0030824787 scopus 로고    scopus 로고
    • Nuclear import, virion incorporation, and cell cycle arrest/differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr
    • Mahalingam, S., Ayyavoo, V., Patel, M., Kieber-Emmons, T., and Weiner, D. B. (1997) Nuclear import, virion incorporation, and cell cycle arrest/differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr. J. Virol. 71, 6339-6347
    • (1997) J. Virol. , vol.71 , pp. 6339-6347
    • Mahalingam, S.1    Ayyavoo, V.2    Patel, M.3    Kieber-Emmons, T.4    Weiner, D.B.5
  • 44
    • 0023392945 scopus 로고
    • High-efficiency transformation of mammalian cells by plasmid DNA
    • Chen, C., and Okayama, H. (1987) High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7, 2745-2752
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 2745-2752
    • Chen, C.1    Okayama, H.2
  • 47
    • 0025695138 scopus 로고
    • Okadaic acid, a potent inhibitor of type 1 and type 2A protein phosphatases, activates cdc2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells
    • Yamashita, K., Yasuda, H., Pines, J., Yasumoto, K., Nishitani, H., Ohtsubo, M., Hunter, T., Sugimura, T., and Nishimoto, T. (1990) Okadaic acid, a potent inhibitor of type 1 and type 2A protein phosphatases, activates cdc2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells. EMBO J. 9, 4331-4338
    • (1990) EMBO J. , vol.9 , pp. 4331-4338
    • Yamashita, K.1    Yasuda, H.2    Pines, J.3    Yasumoto, K.4    Nishitani, H.5    Ohtsubo, M.6    Hunter, T.7    Sugimura, T.8    Nishimoto, T.9
  • 48
    • 0000452806 scopus 로고
    • Chromosome staining and banding
    • Rooney, D. E., and Czepulkpwski, B. H., eds Oxford Press, Oxford, U.K.
    • Benn, P. A., and Perle, M. A. (1992) Chromosome staining and banding. In Human Cytogenetics (Rooney, D. E., and Czepulkpwski, B. H., eds) pp. 91-118, Oxford Press, Oxford, U.K.
    • (1992) Human Cytogenetics , pp. 91-118
    • Benn, P.A.1    Perle, M.A.2
  • 50
    • 0028331965 scopus 로고
    • Molecular and biological characterization of fusion regulatory proteins (FRPs): Anti-FRP mAbs induced HIV-mediated cell fusion via an integrin system
    • Ohta, H., Tsurudome, M., Matsumura, H., Koga, Y., Morikawa, S., Kawano, M., Kusugawa, S., Komada, H., Nishio, M., and Ito, Y. (1994) Molecular and biological characterization of fusion regulatory proteins (FRPs): anti-FRP mAbs induced HIV-mediated cell fusion via an integrin system. EMBO J. 13, 2044-2055
    • (1994) EMBO J. , vol.13 , pp. 2044-2055
    • Ohta, H.1    Tsurudome, M.2    Matsumura, H.3    Koga, Y.4    Morikawa, S.5    Kawano, M.6    Kusugawa, S.7    Komada, H.8    Nishio, M.9    Ito, Y.10
  • 51
    • 0029116836 scopus 로고
    • Molecular characterization of fusion regulatory protein-1 (FRP-1) that induces multinucleated giant cell formation of monocytes and HIV gp160-mediated cell fusion. FRP-1 and 4F2/CD98 are identical molecules
    • Ohgimoto, S., Tabata, N., Suga, S., Nishio, M., Ohta, H., Tsurudome, M., Komada, H., Kawano, M., Watanabe, N., and Ito, Y. (1995) Molecular characterization of fusion regulatory protein-1 (FRP-1) that induces multinucleated giant cell formation of monocytes and HIV gp160-mediated cell fusion. FRP-1 and 4F2/CD98 are identical molecules. J. Immunol. 155, 3585-3592
    • (1995) J. Immunol. , vol.155 , pp. 3585-3592
    • Ohgimoto, S.1    Tabata, N.2    Suga, S.3    Nishio, M.4    Ohta, H.5    Tsurudome, M.6    Komada, H.7    Kawano, M.8    Watanabe, N.9    Ito, Y.10
  • 52
    • 0030451851 scopus 로고    scopus 로고
    • Chemical induction of mitotic checkpoint override in mammalian cells results in aneuploidy following a transient tetraploid state
    • Andreassen, P. R., Martineau, S. N., and Margolis, R. L. (1996) Chemical induction of mitotic checkpoint override in mammalian cells results in aneuploidy following a transient tetraploid state. Mutat. Res. 372, 181-194
    • (1996) Mutat. Res. , vol.372 , pp. 181-194
    • Andreassen, P.R.1    Martineau, S.N.2    Margolis, R.L.3
  • 53
    • 0026562720 scopus 로고
    • Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene
    • Kimpton, J., and Emerman, M. (1992) Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene. J. Virol. 66, 2232-2239
    • (1992) J. Virol. , vol.66 , pp. 2232-2239
    • Kimpton, J.1    Emerman, M.2
  • 54
    • 0022495870 scopus 로고
    • Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
    • Adachi, A., Gendelman, H. E., Koenig, S., Folks, T., Willey, R., Rabson, A., and Martin, M. A. (1986) Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J. Virol. 59, 284-291
    • (1986) J. Virol. , vol.59 , pp. 284-291
    • Adachi, A.1    Gendelman, H.E.2    Koenig, S.3    Folks, T.4    Willey, R.5    Rabson, A.6    Martin, M.A.7
  • 56
    • 0027410459 scopus 로고
    • Induction of cell differentiation by human immunodeficiency virus 1 vpr
    • Levy, D. N., Fernandes, L. S., Williams, W. V., and Weiner, D. B. (1993) Induction of cell differentiation by human immunodeficiency virus 1 vpr. Cell 72, 541-550
    • (1993) Cell , vol.72 , pp. 541-550
    • Levy, D.N.1    Fernandes, L.S.2    Williams, W.V.3    Weiner, D.B.4
  • 58
    • 0027420459 scopus 로고
    • HIV pathogenesis and long-term survival
    • Levy, J. A. (1993) HIV pathogenesis and long-term survival. AIDS 7, 1401-1410
    • (1993) AIDS , vol.7 , pp. 1401-1410
    • Levy, J.A.1
  • 59
    • 0027516822 scopus 로고
    • Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS
    • Embretson, J., Zupancic, M., Ribas, J. L., Burke, A., Racz, P., Tenner-Racz, K., and Haase, A. T. (1993) Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS. Nature (London) 362, 359-362
    • (1993) Nature (London) , vol.362 , pp. 359-362
    • Embretson, J.1    Zupancic, M.2    Ribas, J.L.3    Burke, A.4    Racz, P.5    Tenner-Racz, K.6    Haase, A.T.7
  • 62
    • 0028116938 scopus 로고
    • Serum vpr regulates productive infection and latency of human immunodeficiency virus type 1
    • Levy, D. N., Refaeli, Y., MacGregor, R. R., and Weiner, D. B. (1994) Serum vpr regulates productive infection and latency of human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 91, 10873-10877
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10873-10877
    • Levy, D.N.1    Refaeli, Y.2    MacGregor, R.R.3    Weiner, D.B.4
  • 63
    • 0028797415 scopus 로고
    • Extracellular Vpr protein increases cellular permissiveness to human immunodeficiency virus replication and reactivates virus from latency
    • Levy, D. N., Refaeli, Y., and Weiner, D. B. (1995) Extracellular Vpr protein increases cellular permissiveness to human immunodeficiency virus replication and reactivates virus from latency. J. Virol. 69, 1243-1252
    • (1995) J. Virol. , vol.69 , pp. 1243-1252
    • Levy, D.N.1    Refaeli, Y.2    Weiner, D.B.3
  • 64
    • 0027272082 scopus 로고
    • Induction of micronuclei by HTLV-1 Tax:A cellular assay for function
    • Majone, F., Semmes, O. J., and Jeang, K.-T. (1993) Induction of micronuclei by HTLV-1 Tax:a cellular assay for function. Virology 193, 456-459
    • (1993) Virology , vol.193 , pp. 456-459
    • Majone, F.1    Semmes, O.J.2    Jeang, K.-T.3
  • 65
    • 0029863096 scopus 로고    scopus 로고
    • HTLV-I and HTLV-II tax: Differences in induction of micronuclei in cells and transcriptional activation of viral LTRs
    • Semmes, O. J., Majone, F., Cantemir, C., Turchetto, L., Hjelle, B., and Jeang, K.-T. (1996) HTLV-I and HTLV-II Tax: differences in induction of micronuclei in cells and transcriptional activation of viral LTRs. Virology 217, 373-379
    • (1996) Virology , vol.217 , pp. 373-379
    • Semmes, O.J.1    Majone, F.2    Cantemir, C.3    Turchetto, L.4    Hjelle, B.5    Jeang, K.-T.6
  • 66
    • 10244251532 scopus 로고    scopus 로고
    • Identification of a human mitotic checkpoint gene: hsMAD2
    • Li, Y., and Benezra, R. (1996) Identification of a human mitotic checkpoint gene: hsMAD2. Science 274, 246-248
    • (1996) Science , vol.274 , pp. 246-248
    • Li, Y.1    Benezra, R.2
  • 67
    • 0030608382 scopus 로고    scopus 로고
    • Characterization of a leucine-zipper-like domain in Vpr protein of human immunodeficiency virus type 1
    • Wang, L., Mukherjee, S., Narayan, O., and Zhao, L.-J. (1996) Characterization of a leucine-zipper-like domain in Vpr protein of human immunodeficiency virus type 1. Gene 178, 7-13
    • (1996) Gene , vol.178 , pp. 7-13
    • Wang, L.1    Mukherjee, S.2    Narayan, O.3    Zhao, L.-J.4
  • 68
    • 0028944633 scopus 로고
    • A domain of human immunodeficiency virus type 1 Vpr containing repeated H(S/ F)RIG amino acid motifs causes cell growth arrest and structural defects
    • Macreadie, I. G., Castelli, L. A., Hewish, D. R., Kirkpatrick, A., Ward, A. C., and Azad, A. A. (1995) A domain of human immunodeficiency virus type 1 Vpr containing repeated H(S/ F)RIG amino acid motifs causes cell growth arrest and structural defects. Proc. Natl. Acad. Sci. USA 92, 2770-2774
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2770-2774
    • Macreadie, I.G.1    Castelli, L.A.2    Hewish, D.R.3    Kirkpatrick, A.4    Ward, A.C.5    Azad, A.A.6
  • 69
    • 0031009808 scopus 로고    scopus 로고
    • Small heat shock protein suppression of Vpr-induced cytoskeletal defects in budding yeast
    • Gu, J., Emerman, M., and Sandmeyer, S. (1997) Small heat shock protein suppression of Vpr-induced cytoskeletal defects in budding yeast. Mol Cell. Biol. 17, 4033-4042
    • (1997) Mol Cell. Biol. , vol.17 , pp. 4033-4042
    • Gu, J.1    Emerman, M.2    Sandmeyer, S.3
  • 71
    • 0030700333 scopus 로고    scopus 로고
    • Role of wild type p53 in the G2 phase: Regulation of the gamma-irradiation-induced delay and DNA repair
    • Schwartz, D., Almong, N., Peled, A., Gogfinger, N., and Rotter, V. (1997) Role of wild type p53 in the G2 phase: regulation of the gamma-irradiation-induced delay and DNA repair. Oncogene 15, 2597-2607
    • (1997) Oncogene , vol.15 , pp. 2597-2607
    • Schwartz, D.1    Almong, N.2    Peled, A.3    Gogfinger, N.4    Rotter, V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.