메뉴 건너뛰기




Volumn 14, Issue 9, 2013, Pages 976-988

Cellular targets and mechanisms in the cytotoxic action of non-biodegradable engineered nanoparticles

Author keywords

Cytotoxicity; Genotoxicity; Lysosomes; Metal nanoparticles; Metal oxide nanoparticles; Mitochondria; Plasma membrane; Reactive oxygen species

Indexed keywords

CARBON NANOTUBE; CELL PROTEIN; FULLERENE DERIVATIVE; IRON OXIDE; METAL ION; METAL NANOPARTICLE; NITROGEN DERIVATIVE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; POLYSTYRENE; QUANTUM DOT; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SILICON DIOXIDE; SILVER NANOPARTICLE; TITANIUM DIOXIDE;

EID: 84887969292     PISSN: 13892002     EISSN: 18755453     Source Type: Journal    
DOI: 10.2174/1389200211314090004     Document Type: Article
Times cited : (146)

References (158)
  • 1
    • 35348852487 scopus 로고    scopus 로고
    • Occurrence, behavior and effects of nanoparticles in the environment
    • Nowack, B.; Bucheli, T.D. Occurrence, behavior and effects of nanoparticles in the environment. Environ. Pollut., 2007, 150, 5-22.
    • (2007) Environ. Pollut. , vol.150 , pp. 5-22
    • Nowack, B.1    Bucheli, T.D.2
  • 3
    • 84860796920 scopus 로고    scopus 로고
    • Cytotoxicity of nanoparticles is influenced by size, proliferation and embryonic origin of the cells used for testing
    • (a) Fröhlich, E.; Meindl, C.; Roblegg, E.; Griesbacher, A.; Pieber, T.R. Cytotoxicity of nanoparticles is influenced by size, proliferation and embryonic origin of the cells used for testing. Nanotoxicology, 2012, 6, 424-423;
    • (2012) Nanotoxicology , vol.6 , pp. 424-423
    • Fröhlich, E.1    Meindl, C.2    Roblegg, E.3    Griesbacher, A.4    Pieber, T.R.5
  • 4
    • 79955713975 scopus 로고    scopus 로고
    • BSA adsorption on differently charged polystyrene nanoparticles using isothermal titration calorimetry and the influence on cellular uptake
    • (b) Baier, G.; Costa, C.; Zeller, A.; Baumann, D.; Sayer, C.; Araujo, P. H.; Mailander, V.; Musyanovych, A.; Landfester, K. BSA adsorption on differently charged polystyrene nanoparticles using isothermal titration calorimetry and the influence on cellular uptake. Macromol. Biosci., 2011, 11, 628-638;
    • (2011) Macromol. Biosci. , vol.11 , pp. 628-638
    • Baier, G.1    Costa, C.2    Zeller, A.3    Baumann, D.4    Sayer, C.5    Araujo, P.H.6    Mailander, V.7    Musyanovych, A.8    Landfester, K.9
  • 5
    • 70349279929 scopus 로고    scopus 로고
    • Relevance of the colloidal stability of chitosan/PLGA nanoparticles on their cytotoxicity profile
    • (c) Nafee, N.; Schneider, M.; Schaefer, U. F.; Lehr, C.M. Relevance of the colloidal stability of chitosan/PLGA nanoparticles on their cytotoxicity profile. Int. J. Pharm., 2009, 381, 130-139
    • (2009) Int. J. Pharm. , vol.381 , pp. 130-139
    • Nafee, N.1    Schneider, M.2    Schaefer, U.F.3    Lehr, C.M.4
  • 6
    • 36549029204 scopus 로고    scopus 로고
    • Effect of cell media on polymer coated superparamagnetic iron oxide nanoparticles (SPIONs): Colloidal stability, cytotoxicity, and cellular uptake studies
    • (d) Petri-Fink, A.; Steitz, B.; Finka, A.; Salaklang, J.; Hofmann, H. Effect of cell media on polymer coated superparamagnetic iron oxide nanoparticles (SPIONs): colloidal stability, cytotoxicity, and cellular uptake studies. Eur. J. Pharm. Biopharm., 2008, 68, 129-137.
    • (2008) Eur. J. Pharm. Biopharm. , vol.68 , pp. 129-137
    • Petri-Fink, A.1    Steitz, B.2    Finka, A.3    Salaklang, J.4    Hofmann, H.5
  • 7
    • 84864258079 scopus 로고    scopus 로고
    • The effect of nanoparticle size, shape, and surface chemistry on biological systems
    • Albanese, A.; Tang, P. S.; Chan, W. C. The effect of nanoparticle size, shape, and surface chemistry on biological systems. Annu. Rev. Biomed. Eng., 2012, 14, 1-16.
    • (2012) Annu. Rev. Biomed. Eng. , vol.14 , pp. 1-16
    • Albanese, A.1    Tang, P.S.2    Chan, W.C.3
  • 10
    • 84865310538 scopus 로고    scopus 로고
    • The delivered dose: Applying particokinetics to in vitro investigations of nanoparticle internalization by macrophages
    • Ahmad Khanbeigi, R.; Kumar, A.; Sadouki, F.; Lorenz, C.; Forbes, B.; Dailey, L. A.; Collins, H. The delivered dose: Applying particokinetics to in vitro investigations of nanoparticle internalization by macrophages. J. Control. Release, 2012, 162, 259-266.
    • (2012) J. Control. Release , vol.162 , pp. 259-266
    • Ahmad Khanbeigi, R.1    Kumar, A.2    Sadouki, F.3    Lorenz, C.4    Forbes, B.5    Dailey, L.A.6    Collins, H.7
  • 11
    • 79960132035 scopus 로고    scopus 로고
    • The effect of sedimentation and diffusion on cellular uptake of gold nanoparticles
    • Cho, E. C.; Zhang, Q.; Xia, Y. The effect of sedimentation and diffusion on cellular uptake of gold nanoparticles. Nat. Nanotechnol., 2011, 6, 385-391.
    • (2011) Nat. Nanotechnol. , vol.6 , pp. 385-391
    • Cho, E.C.1    Zhang, Q.2    Xia, Y.3
  • 16
    • 84874007002 scopus 로고    scopus 로고
    • Assessment of long-term effects of nanoparticles in a MiCROCARRIER cell culture system
    • Mrakovcic, M.; Absenger, M.; Riedl, R.; Roblegg, E.; Fröhlich, E. Assessment of long-term effects of nanoparticles in a MiCROCARRIER cell culture system. PLoS One, 2013, 8, e56791.
    • (2013) PLoS One , vol.8
    • Mrakovcic, M.1    Absenger, M.2    Riedl, R.3    Roblegg, E.4    Fröhlich, E.5
  • 17
    • 77956363461 scopus 로고    scopus 로고
    • Calcium-enhanced exocytosis of gold nanoparticles
    • (a) Chen, R.; Huang, G.; Ke, P. Calcium-enhanced exocytosis of gold nanoparticles. Appl. Phy. Lett., 2010, 97;
    • (2010) Appl. Phy. Lett. , vol.97
    • Chen, R.1    Huang, G.2    Ke, P.3
  • 18
    • 77956494898 scopus 로고    scopus 로고
    • Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells
    • (b) Bhattacharjee, S.; de Haan, L. H.; Evers, N. M.; Jiang, X.; Marcelis, A. T.; Zuilhof, H.; Rietjens, I. M.; Alink, G. M. Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells. Part. Fibre Toxicol., 2010, 7, 25;
    • (2010) Part. Fibre Toxicol. , vol.7 , pp. 25
    • Bhattacharjee, S.1    De Haan, L.H.2    Evers, N.M.3    Jiang, X.4    Marcelis, A.T.5    Zuilhof, H.6    Rietjens, I.M.7    Alink, G.M.8
  • 19
    • 84870338385 scopus 로고    scopus 로고
    • Biocompatibility, endocytosis, and intracellular trafficking of mesoporous silica and polystyrene nanoparticles in ovarian cancer cells: Effects of size and surface charge groups
    • (c) Ekkapongpisit, M.; Giovia, A.; Follo, C.; Caputo, G.; Isidoro, C. Biocompatibility, endocytosis, and intracellular trafficking of mesoporous silica and polystyrene nanoparticles in ovarian cancer cells: effects of size and surface charge groups. Int. J. Nanomedicine, 2012, 7, 4147-4158.
    • (2012) Int. J. Nanomedicine , vol.7 , pp. 4147-4158
    • Ekkapongpisit, M.1    Giovia, A.2    Follo, C.3    Caputo, G.4    Isidoro, C.5
  • 20
    • 34547302844 scopus 로고    scopus 로고
    • Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes
    • Chithrani, B. D.; Chan, W. C. Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes. Nano Lett., 2007, 7, 1542-1550.
    • (2007) Nano Lett. , vol.7 , pp. 1542-1550
    • Chithrani, B.D.1    Chan, W.C.2
  • 22
    • 83355166280 scopus 로고    scopus 로고
    • Induction of ROS, mitochondrial damage and autophagy in lung epithelial cancer cells by iron oxide nanoparticles
    • Khan, M. I.; Mohammad, A.; Patil, G.; Naqvi, S. A.; Chauhan, L. K.; Ahmad, I. Induction of ROS, mitochondrial damage and autophagy in lung epithelial cancer cells by iron oxide nanoparticles. Biomaterials, 2012, 33, 1477-1488.
    • (2012) Biomaterials , vol.33 , pp. 1477-1488
    • Khan, M.I.1    Mohammad, A.2    Patil, G.3    Naqvi, S.A.4    Chauhan, L.K.5    Ahmad, I.6
  • 23
    • 0035984827 scopus 로고    scopus 로고
    • Comparative in vitro sensitivities of human immune cell lines, vaginal and cervical epithelial cell lines, and primary cells to candidate microbicides nonoxynol 9, C31G, and sodium dodecyl sulfate
    • (a) Krebs, F. C.; Miller, S. R.; Catalone, B. J.; Fichorova, R.; Anderson, D.; Malamud, D.; Howett, M. K.; Wigdahl, B. Comparative in vitro sensitivities of human immune cell lines, vaginal and cervical epithelial cell lines, and primary cells to candidate microbicides nonoxynol 9, C31G, and sodium dodecyl sulfate. Antimicrob. Agents Chemother., 2002, 46, 2292-2298;
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 2292-2298
    • Krebs, F.C.1    Miller, S.R.2    Catalone, B.J.3    Fichorova, R.4    Anderson, D.5    Malamud, D.6    Howett, M.K.7    Wigdahl, B.8
  • 25
    • 84887857196 scopus 로고    scopus 로고
    • Combination of small size and carboxyl functionalisation causes cytotoxicity of short carbon nanotubes
    • Oct 9, [Epub ahead of print]
    • (a) Fröhlich, E.; Meindl, C.; Höfler, A.; Leitinger, G.; Roblegg, E. Combination of small size and carboxyl functionalisation causes cytotoxicity of short carbon nanotubes. Nanotoxicology, 2012, Oct 9, [Epub ahead of print]
    • (2012) Nanotoxicology
    • Fröhlich, E.1    Meindl, C.2    Höfler, A.3    Leitinger, G.4    Roblegg, E.5
  • 26
    • 0043028532 scopus 로고    scopus 로고
    • Comparative particle-induced cytotoxicity toward macrophages and fibroblasts
    • Olivier, V.; Duval, J. L.; Hindie, M.; Pouletaut, P.; Nagel, M.D. Comparative particle-induced cytotoxicity toward macrophages and fibroblasts. Cell Biol. Toxicol., 2003, 19, 145-159;
    • (2003) Cell Biol. Toxicol. , vol.19 , pp. 145-159
    • Olivier, V.1    Duval, J.L.2    Hindie, M.3    Pouletaut, P.4    Nagel, M.D.5
  • 29
    • 33846794848 scopus 로고    scopus 로고
    • Studying hostpathogen interactions in 3-D: Organotypic models for infectious disease and drug development
    • (b) Nickerson, C. A.; Richter, E. G.; Ott, C. M. Studying hostpathogen interactions in 3-D: organotypic models for infectious disease and drug development. J. Neuroimmune Pharmacol., 2007, 2, 26-31.
    • (2007) J. Neuroimmune Pharmacol. , vol.2 , pp. 26-31
    • Nickerson, C.A.1    Richter, E.G.2    Ott, C.M.3
  • 30
    • 78751560396 scopus 로고    scopus 로고
    • High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array
    • Tung, Y. C.; Hsiao, A. Y.; Allen, S. G.; Torisawa, Y. S.; Ho, M.; Takayama, S. High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array. Analyst, 2011, 136, 473-478.
    • (2011) Analyst , vol.136 , pp. 473-478
    • Tung, Y.C.1    Hsiao, A.Y.2    Allen, S.G.3    Torisawa, Y.S.4    Ho, M.5    Takayama, S.6
  • 31
    • 80051483471 scopus 로고    scopus 로고
    • The effects of serum on the toxicity of manufactured nanoparticles
    • (a) Clift, M. J.; Bhattacharjee, S.; Brown, D. M.; Stone, V. The effects of serum on the toxicity of manufactured nanoparticles. Toxicol. Lett. 2010, 198, 358-365;
    • (2010) Toxicol. Lett. , vol.198 , pp. 358-365
    • Clift, M.J.1    Bhattacharjee, S.2    Brown, D.M.3    Stone, V.4
  • 32
    • 10044273054 scopus 로고    scopus 로고
    • Factors regulating macrophage endocytosis of nanoparticles: Implications for targeted magnetic resonance plaque imaging
    • (b) Rogers, W. J.; Basu, P., Factors regulating macrophage endocytosis of nanoparticles: implications for targeted magnetic resonance plaque imaging. Atherosclerosis 2005, 178, 67-73.
    • (2005) Atherosclerosis , vol.178 , pp. 67-73
    • Rogers, W.J.1    Basu, P.2
  • 33
    • 84886397566 scopus 로고    scopus 로고
    • Important issues in the cytotoxicity screening of nano-sized materials
    • (a) Fröhlich, E.; Meindl, C.; Pieber, T. Important issues in the cytotoxicity screening of nano-sized materials. EURO-NanoTox Lett., 2010, 1, 1-6;
    • (2010) EURO-NanoTox Lett. , vol.1 , pp. 1-6
    • Fröhlich, E.1    Meindl, C.2    Pieber, T.3
  • 34
    • 67349284747 scopus 로고    scopus 로고
    • Current in vitro methods in nanoparticle risk assessment: Limitations and challenges
    • (b) Kroll, A.; Pillukat, M. H.; Hahn, D.; Schnekenburger, J., Current in vitro methods in nanoparticle risk assessment: limitations and challenges. Eur. J. Pharm. Biopharm., 2009, 72, 370-377;
    • (2009) Eur. J. Pharm. Biopharm. , vol.72 , pp. 370-377
    • Kroll, A.1    Pillukat, M.H.2    Hahn, D.3    Schnekenburger, J.4
  • 35
    • 58149267870 scopus 로고    scopus 로고
    • Limitations and relative utility of screening assays to assess engineered nanoparticle toxicity in a human cell line
    • (c) Monteiro-Riviere, N. A.; Inman, A. O.; Zhang, L. W. Limitations and relative utility of screening assays to assess engineered nanoparticle toxicity in a human cell line. Toxicol. Appl. Pharmacol., 2009, 234, 222-235.
    • (2009) Toxicol. Appl. Pharmacol. , vol.234 , pp. 222-235
    • Monteiro-Riviere, N.A.1    Inman, A.O.2    Zhang, L.W.3
  • 38
    • 33748310797 scopus 로고    scopus 로고
    • Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm
    • Xia, T.; Kovochich, M.; Brant, J.; Hotze, M.; Sempf, J.; Oberley, T.; Sioutas, C.; Yeh, J. I.; Wiesner, M. R.; Nel, A. E. Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano Lett., 2006, 6, 1794-1807.
    • (2006) Nano Lett. , vol.6 , pp. 1794-1807
    • Xia, T.1    Kovochich, M.2    Brant, J.3    Hotze, M.4    Sempf, J.5    Oberley, T.6    Sioutas, C.7    Yeh, J.I.8    Wiesner, M.R.9    Nel, A.E.10
  • 39
    • 67651250041 scopus 로고    scopus 로고
    • Titanium dioxide nanoparticles induce oxidative stress and DNA-adduct formation but not DNA-breakage in human lung cells
    • (a) Bhattacharya, K.; Davoren, M.; Boertz, J.; Schins, R. P.; Hoffmann, E.; Dopp, E. Titanium dioxide nanoparticles induce oxidative stress and DNA-adduct formation but not DNA-breakage in human lung cells. Part. Fibre Toxicol., 2009, 6, 17;
    • (2009) Part. Fibre Toxicol. , vol.6 , pp. 17
    • Bhattacharya, K.1    Davoren, M.2    Boertz, J.3    Schins, R.P.4    Hoffmann, E.5    Dopp, E.6
  • 41
    • 84859141837 scopus 로고    scopus 로고
    • Effects of surface chemistry on the generation of reactive oxygen species by copper nanoparticles
    • (c) Shi, M.; Kwon, H. S.; Peng, Z.; Elder, A.; Yang, H. Effects of surface chemistry on the generation of reactive oxygen species by copper nanoparticles. ACS Nano, 2012, 6, 2157-2164.
    • (2012) ACS Nano , vol.6 , pp. 2157-2164
    • Shi, M.1    Kwon, H.S.2    Peng, Z.3    Elder, A.4    Yang, H.5
  • 42
    • 34347352996 scopus 로고    scopus 로고
    • Impact of silanol surface density on the toxicity of silica aerosols measured by erythrocyte haemolysis
    • (a) Murashov, V.; Harper, M.; Demchuk, E. Impact of silanol surface density on the toxicity of silica aerosols measured by erythrocyte haemolysis. J. Occup. Environ. Hyg., 2006, 3, 718-723;
    • (2006) J. Occup. Environ. Hyg. , vol.3 , pp. 718-723
    • Murashov, V.1    Harper, M.2    Demchuk, E.3
  • 43
    • 78650982804 scopus 로고    scopus 로고
    • Surface-mediated production of hydroxyl radicals as a mechanism of iron oxide nanoparticle biotoxicity
    • (b) Voinov, M. A.; Sosa Pagan, J. O.; Morrison, E.; Smirnova, T. I.; Smirnov, A. I., Surface-mediated production of hydroxyl radicals as a mechanism of iron oxide nanoparticle biotoxicity. J. Am. Chem. Soc., 2011, 133, 35-41.
    • (2011) Am. Chem. Soc. , vol.133 , pp. 35-41
    • Voinov, M.A.1    Sosa Pagan, J.O.2    Morrison, E.3    Smirnova, T.I.4    Smirnov, A.I.5
  • 44
    • 79959342430 scopus 로고    scopus 로고
    • Toxicity of transition metal oxide nanoparticles: Recent Insights from in vitro Studies
    • Huang, Y.; Wu, C.; Aronstam, R. Toxicity of transition metal oxide nanoparticles: Recent Insights from In vitro Studies. Materials, 2010, 3, 4842-4859.
    • (2010) Materials , vol.3 , pp. 4842-4859
    • Huang, Y.1    Wu, C.2    Aronstam, R.3
  • 46
    • 84862925782 scopus 로고    scopus 로고
    • Zinc oxide nanoparticles interfere with zinc ion homeostasis to cause cytotoxicity
    • Kao, Y. Y.; Chen, Y. C.; Cheng, T. J.; Chiung, Y. M.; Liu, P. S. Zinc oxide nanoparticles interfere with zinc ion homeostasis to cause cytotoxicity. Toxicol. Sci., 2012, 125, 462-472.
    • (2012) Toxicol. Sci. , vol.125 , pp. 462-472
    • Kao, Y.Y.1    Chen, Y.C.2    Cheng, T.J.3    Chiung, Y.M.4    Liu, P.S.5
  • 47
    • 56049106549 scopus 로고    scopus 로고
    • Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties
    • Xia, T.; Kovochich, M.; Liong, M.; Madler, L.; Gilbert, B.; Shi, H.; Yeh, J. I.; Zink, J. I.; Nel, A. E. Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties. ACS Nano, 2008, 2, 2121-2134.
    • (2008) ACS Nano , vol.2 , pp. 2121-2134
    • Xia, T.1    Kovochich, M.2    Liong, M.3    Madler, L.4    Gilbert, B.5    Shi, H.6    Yeh, J.I.7    Zink, J.I.8    Nel, A.E.9
  • 48
    • 0036089783 scopus 로고    scopus 로고
    • Silver ions induce Ca2+ release from the SR in vitro by acting on the Ca2+ release channel and the Ca2+ pump
    • Tupling, R.; Green, H. Silver ions induce Ca2+ release from the SR in vitro by acting on the Ca2+ release channel and the Ca2+ pump. J. Appl. Physiol., 2002, 92, 1603-1610.
    • (2002) J. Appl. Physiol. , vol.92 , pp. 1603-1610
    • Tupling, R.1    Green, H.2
  • 50
    • 84887862378 scopus 로고    scopus 로고
    • In vitro cytotoxicity and induction of apoptosis by multiwalled carbon nanotubes in human peripheral lymphocytes: Correlation with physicochemical properties
    • Elshal, M.; Salam, M.; Khan, J. In vitro cytotoxicity and induction of apoptosis by multiwalled carbon nanotubes in human peripheral lymphocytes: Correlation with physicochemical properties. Afr. J. Biotechnol., 2012, 11, 11455-11462.
    • (2012) Afr. J. Biotechnol. , vol.11 , pp. 11455-11462
    • Elshal, M.1    Salam, M.2    Khan, J.3
  • 53
    • 77957324488 scopus 로고    scopus 로고
    • Penetration of lipid membranes by gold nanoparticles: Insights into cellular uptake, cytotoxicity, and their relationship
    • Lin, J.; Zhang, H.; Chen, Z.; Zheng, Y. Penetration of lipid membranes by gold nanoparticles: insights into cellular uptake, cytotoxicity, and their relationship. ACS Nano, 2010, 4, 5421-5429.
    • (2010) ACS Nano , vol.4 , pp. 5421-5429
    • Lin, J.1    Zhang, H.2    Chen, Z.3    Zheng, Y.4
  • 54
    • 84857772044 scopus 로고    scopus 로고
    • Cellular uptake of nanoparticles by membrane penetration: A study combining confocal microscopy with FTIR spectroelectrochemistry
    • (a) Wang, T.; Bai, J.; Jiang, X.; Nienhaus, G. U. Cellular Uptake of Nanoparticles by Membrane Penetration: A Study Combining Confocal Microscopy with FTIR Spectroelectrochemistry. ACS Nano, 2012, 6, 1251-1259;
    • (2012) ACS Nano , vol.6 , pp. 1251-1259
    • Wang, T.1    Bai, J.2    Jiang, X.3    Nienhaus, G.U.4
  • 55
    • 84864414649 scopus 로고    scopus 로고
    • The crystalline forms of titanium dioxide nanoparticles affect their interactions with individual cells
    • (b) Ryabchikova, E.; Mazurkova, N.; Shikina, N.; Ismagilov, Z. The Crystalline Forms Of Titanium Dioxide Nanoparticles Affect Their Interactions With Individual Cells. J. Med. CBR, 2010, 8.
    • (2010) J. Med. CBR , vol.8
    • Ryabchikova, E.1    Mazurkova, N.2    Shikina, N.3    Ismagilov, Z.4
  • 56
    • 33947421291 scopus 로고    scopus 로고
    • Examination of nonendocytotic bulk transport of nanoparticles across phospholipid membranes
    • (a) Banerji, S. K.; Hayes, M. A. Examination of nonendocytotic bulk transport of nanoparticles across phospholipid membranes. Langmuir, 2007, 23, 3305-3313;
    • (2007) Langmuir , vol.23 , pp. 3305-3313
    • Banerji, S.K.1    Hayes, M.A.2
  • 57
    • 77956428533 scopus 로고    scopus 로고
    • Hydrophobic gold nanoparticle self-assembly with phosphatidylcholine lipid: Membrane-loaded and janus vesicles
    • (b) Rasch, M. R.; Rossinyol, E.; Hueso, J. L.; Goodfellow, B. W.; Arbiol, J.; Korgel, B. A. Hydrophobic gold nanoparticle self-assembly with phosphatidylcholine lipid: membrane-loaded and janus vesicles. Nano Lett., 2010, 10, 3733-3739.
    • (2010) Nano Lett. , vol.10 , pp. 3733-3739
    • Rasch, M.R.1    Rossinyol, E.2    Hueso, J.L.3    Goodfellow, B.W.4    Arbiol, J.5    Korgel, B.A.6
  • 59
    • 78649379582 scopus 로고    scopus 로고
    • C-Src-mediated activation of Erk1/2 is a reaction of epithelial cells to carbon nanoparticle treatment and may be a target for a molecular preventive strategy
    • (a) Peuschel, H.; Sydlik, U.; Haendeler, J.; Buchner, N.; Stockmann, D.; Kroker, M.; Wirth, R.; Brock, W.; Unfried, K. c-Src-mediated activation of Erk1/2 is a reaction of epithelial cells to carbon nanoparticle treatment and may be a target for a molecular preventive strategy. Biol. Chem., 2010, 391, 1327-1332;
    • (2010) Biol. Chem. , vol.391 , pp. 1327-1332
    • Peuschel, H.1    Sydlik, U.2    Haendeler, J.3    Buchner, N.4    Stockmann, D.5    Kroker, M.6    Wirth, R.7    Brock, W.8    Unfried, K.9
  • 60
    • 33749330049 scopus 로고    scopus 로고
    • Ultrafine carbon particles induce apoptosis and proliferation in rat lung epithelial cells via specific signaling pathways both using EGF-R
    • (b) Sydlik, U.; Bierhals, K.; Soufi, M.; Abel, J.; Schins, R. P.; Unfried, K. Ultrafine carbon particles induce apoptosis and proliferation in rat lung epithelial cells via specific signaling pathways both using EGF-R. Am. J. Physiol. Lung Cell Mol. Physiol., 2006, 291, L725-733.
    • (2006) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.291
    • Sydlik, U.1    Bierhals, K.2    Soufi, M.3    Abel, J.4    Schins, R.P.5    Unfried, K.6
  • 61
    • 84870818714 scopus 로고    scopus 로고
    • Cell type-specific activation of AKT and ERK signaling pathways by small negatively-charged magnetic nanoparticles
    • Rauch, J.; Kolch, W.; Mahmoudi, M. Cell type-specific activation of AKT and ERK signaling pathways by small negatively-charged magnetic nanoparticles. Sci. Rep., 2012, 2, 868.
    • (2012) Sci. Rep. , vol.2 , pp. 868
    • Rauch, J.1    Kolch, W.2    Mahmoudi, M.3
  • 62
    • 84862180734 scopus 로고    scopus 로고
    • Genotoxicity and molecular response of silver nanoparticle (NP)-based hydrogel
    • Xu, L.; Li, X.; Takemura, T.; Hanagata, N.; Wu, G.; Chou, L. L. Genotoxicity and molecular response of silver nanoparticle (NP)-based hydrogel. J. Nanobiotechnol.,2012, 10, 16.
    • (2012) J. Nanobiotechnol. , vol.10 , pp. 16
    • Xu, L.1    Li, X.2    Takemura, T.3    Hanagata, N.4    Wu, G.5    Chou, L.L.6
  • 64
    • 0037114818 scopus 로고    scopus 로고
    • Chromium(III)-induced apoptosis of lymphocytes: Death decision by ROS and Src-family tyrosine kinases
    • (b) Balamurugan, K.; Rajaram, R.; Ramasami, T.; Narayanan, S. Chromium(III)-induced apoptosis of lymphocytes: death decision by ROS and Src-family tyrosine kinases. Free Radical Biol. Med., 2002, 33, 1622-1640.
    • (2002) Free Radical Biol. Med. , vol.33 , pp. 1622-1640
    • Balamurugan, K.1    Rajaram, R.2    Ramasami, T.3    Narayanan, S.4
  • 66
    • 84866009247 scopus 로고    scopus 로고
    • EPR spin trapping evaluation of ROS production in human fibroblasts exposed to cerium oxide nanoparticles: Evidence for NADPH oxidase and mitochondrial stimulation
    • Culcasi, M.; Benameur, L.; Mercier, A.; Lucchesi, C.; Rahmouni, H.; Asteian, A.; Casano, G.; Botta, A.; Kovacic, H.; Pietri, S. EPR spin trapping evaluation of ROS production in human fibroblasts exposed to cerium oxide nanoparticles: evidence for NADPH oxidase and mitochondrial stimulation. Chem. Biol. Interact., 2012, 199, 161-176.
    • (2012) Chem. Biol. Interact. , vol.199 , pp. 161-176
    • Culcasi, M.1    Benameur, L.2    Mercier, A.3    Lucchesi, C.4    Rahmouni, H.5    Asteian, A.6    Casano, G.7    Botta, A.8    Kovacic, H.9    Pietri, S.10
  • 67
    • 34447557692 scopus 로고    scopus 로고
    • The effects of PM10 particles and oxidative stress on macrophages and lung epithelial cells: Modulating effects of calcium-signaling antagonists
    • (a) Brown, D. M.; Hutchison, L.; Donaldson, K.; Stone, V. The effects of PM10 particles and oxidative stress on macrophages and lung epithelial cells: modulating effects of calcium-signaling antagonists. Am. J. Physiol., 2007, 292, L1444-1451;
    • (2007) Am. J. Physiol. , vol.292
    • Brown, D.M.1    Hutchison, L.2    Donaldson, K.3    Stone, V.4
  • 69
    • 79251602398 scopus 로고    scopus 로고
    • Mucin secretion induced by titanium dioxide nanoparticles
    • (a) Chen, E. Y.; Garnica, M.; Wang, Y. C.; Chen, C. S.; Chin, W. C. Mucin secretion induced by titanium dioxide nanoparticles. PLoS One, 2011, 6, e16198;
    • (2011) PLoS One , vol.6
    • Chen, E.Y.1    Garnica, M.2    Wang, Y.C.3    Chen, C.S.4    Chin, W.C.5
  • 70
    • 72049093217 scopus 로고    scopus 로고
    • Oxidative stress, calcium homeostasis, and altered gene expression in human lung epithelial cells exposed to ZnO nanoparticles
    • (b) Huang, C. C.; Aronstam, R. S.; Chen, D. R.; Huang, Y. W. Oxidative stress, calcium homeostasis, and altered gene expression in human lung epithelial cells exposed to ZnO nanoparticles. Toxicol. In Vitro, 2010, 24, 45-55;
    • (2010) Toxicol. in Vitro , vol.24 , pp. 45-55
    • Huang, C.C.1    Aronstam, R.S.2    Chen, D.R.3    Huang, Y.W.4
  • 71
    • 80455173408 scopus 로고    scopus 로고
    • Polystyrene nanoparticles activate ion transport in human airway epithelial cells
    • (c) McCarthy, J.; Gong, X.; Nahirney, D.; Duszyk, M.; Radomski, M. Polystyrene nanoparticles activate ion transport in human airway epithelial cells. Int. J. Nanomed., 2011, 6, 1343-1356.
    • (2011) Int. J. Nanomed. , vol.6 , pp. 1343-1356
    • McCarthy, J.1    Gong, X.2    Nahirney, D.3    Duszyk, M.4    Radomski, M.5
  • 72
    • 84864715995 scopus 로고    scopus 로고
    • Labeling and exocytosis of secretory compartments in RBL mastocytes by polystyrene and mesoporous silica nanoparticles
    • Ekkapongpisit, M.; Giovia, A.; Nicotra, G.; Ozzano, M.; Caputo, G.; Isidoro, C. Labeling and exocytosis of secretory compartments in RBL mastocytes by polystyrene and mesoporous silica nanoparticles. Int. J. Nanomed., 2012, 7, 1829-1840.
    • (2012) Int. J. Nanomed. , vol.7 , pp. 1829-1840
    • Ekkapongpisit, M.1    Giovia, A.2    Nicotra, G.3    Ozzano, M.4    Caputo, G.5    Isidoro, C.6
  • 73
    • 46749130939 scopus 로고    scopus 로고
    • Unmodified CdSe quantum dots induce elevation of cytoplasmic calcium levels and impairment of functional properties of sodium channels in rat primary cultured hippocampal neurons
    • Tang, M.; Xing, T.; Zeng, J.; Wang, H.; Li, C.; Yin, S.; Yan, D.; Deng, H.; Liu, J.; Wang, M.; Chen, J.; Ruan, D. Y. Unmodified CdSe quantum dots induce elevation of cytoplasmic calcium levels and impairment of functional properties of sodium channels in rat primary cultured hippocampal neurons. Environ. Health Perspect., 2008, 116, 915-922.
    • (2008) Environ. Health Perspect. , vol.116 , pp. 915-922
    • Tang, M.1    Xing, T.2    Zeng, J.3    Wang, H.4    Li, C.5    Yin, S.6    Yan, D.7    Deng, H.8    Liu, J.9    Wang, M.10    Chen, J.11    Ruan, D.Y.12
  • 74
    • 79952310883 scopus 로고    scopus 로고
    • Nanoparticles attenuate Pglycoprotein/ MDR1 function in A549 human alveolar epithelial cells
    • Salomon, J. J.; Ehrhardt, C. Nanoparticles attenuate Pglycoprotein/ MDR1 function in A549 human alveolar epithelial cells. Eur. J. Pharm. Biopharm., 2011, 77, 392-397.
    • (2011) Eur. J. Pharm. Biopharm. , vol.77 , pp. 392-397
    • Salomon, J.J.1    Ehrhardt, C.2
  • 75
    • 33646397592 scopus 로고    scopus 로고
    • Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells
    • (a) Chithrani, B. D.; Ghazani, A. A.; Chan, W. C. Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. Nano Lett., 2006, 6, 662-668;
    • (2006) Nano Lett. , vol.6 , pp. 662-668
    • Chithrani, B.D.1    Ghazani, A.A.2    Chan, W.C.3
  • 78
    • 0348087040 scopus 로고    scopus 로고
    • Long-term multiple color imaging of live cells using quantum dot bioconjugates
    • (d) Jaiswal, J. K.; Mattoussi, H.; Mauro, J. M.; Simon, S. M. Long-term multiple color imaging of live cells using quantum dot bioconjugates. Nat. Biotechnol., 2003, 21, 47-51;
    • (2003) Nat. Biotechnol. , vol.21 , pp. 47-51
    • Jaiswal, J.K.1    Mattoussi, H.2    Mauro, J.M.3    Simon, S.M.4
  • 79
    • 51849119730 scopus 로고    scopus 로고
    • Uptake and intracellular fate of surface-modified gold nanoparticles
    • (e) Nativo, P.; Prior, I. A.; Brust, M. Uptake and intracellular fate of surface-modified gold nanoparticles. ACS Nano, 2008, 2, 1639-1644;
    • (2008) ACS Nano , vol.2 , pp. 1639-1644
    • Nativo, P.1    Prior, I.A.2    Brust, M.3
  • 80
    • 1642575957 scopus 로고    scopus 로고
    • Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis
    • (f) Rejman, J.; Oberle, V.; Zuhorn, I. S.; Hoekstra, D. Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis. Biochem. J., 2004, 377, 159-169;
    • (2004) Biochem. J. , vol.377 , pp. 159-169
    • Rejman, J.1    Oberle, V.2    Zuhorn, I.S.3    Hoekstra, D.4
  • 83
    • 53549131701 scopus 로고    scopus 로고
    • Cytotoxicity of titanium dioxide nanoparticles in mouse fibroblast cells
    • (b) Jin, C. Y.; Zhu, B. S.; Wang, X. F.; Lu, Q. H. Cytotoxicity of titanium dioxide nanoparticles in mouse fibroblast cells. Chem. Res. Toxicol., 2008, 21, 1871-1877.
    • (2008) Chem. Res. Toxicol. , vol.21 , pp. 1871-1877
    • Jin, C.Y.1    Zhu, B.S.2    Wang, X.F.3    Lu, Q.H.4
  • 84
    • 33750999930 scopus 로고    scopus 로고
    • Three-dimensional reconstruction of cell nuclei, internalized quantum dots and sites of lipid peroxidation
    • Funnell, W. R.; Maysinger, D. Three-dimensional reconstruction of cell nuclei, internalized quantum dots and sites of lipid peroxidation. J. Nanobiotechnol., 2006, 4, 10.
    • (2006) J. Nanobiotechnol. , vol.4 , pp. 10
    • Funnell, W.R.1    Maysinger, D.2
  • 85
    • 77957303896 scopus 로고    scopus 로고
    • Surface-chargedependent cell localization and cytotoxicity of cerium oxide nanoparticles
    • Asati, A.; Santra, S.; Kaittanis, C.; Perez, J. M. Surface- chargedependent cell localization and cytotoxicity of cerium oxide nanoparticles. ACS Nano, 2010, 4, 5321-5331.
    • (2010) ACS Nano , vol.4 , pp. 5321-5331
    • Asati, A.1    Santra, S.2    Kaittanis, C.3    Perez, J.M.4
  • 87
    • 84866045532 scopus 로고    scopus 로고
    • A review of mammalian toxicity of ZnO nanoparticles
    • Vandebriel, R.; De Jong, W. A review of mammalian toxicity of ZnO nanoparticles Nanotechnol. Sci. Appl., 2012, 5, 61-71.
    • (2012) Nanotechnol. Sci. Appl. , vol.5 , pp. 61-71
    • Vandebriel, R.1    De Jong, W.2
  • 91
    • 3242808193 scopus 로고    scopus 로고
    • Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity
    • Thibodeau, M. S.; Giardina, C.; Knecht, D. A.; Helble, J.; Hubbard, A. K. Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity. Toxicol. Sci., 2004, 80, 34-48.
    • (2004) Toxicol. Sci. , vol.80 , pp. 34-48
    • Thibodeau, M.S.1    Giardina, C.2    Knecht, D.A.3    Helble, J.4    Hubbard, A.K.5
  • 92
    • 84855611478 scopus 로고    scopus 로고
    • Crucial ignored parameters on nanotoxicology: The importance of toxicity assay modifications and "cell vision"
    • Laurent, S.; Burtea, C.; Thirifays, C.; Hafeli, U. O.; Mahmoudi, M. Crucial ignored parameters on nanotoxicology: the importance of toxicity assay modifications and "cell vision". PLoS One, 2012, 7, e29997.
    • (2012) PLoS One , vol.7
    • Laurent, S.1    Burtea, C.2    Thirifays, C.3    Hafeli, U.O.4    Mahmoudi, M.5
  • 93
    • 80053922007 scopus 로고    scopus 로고
    • Cellular toxicity of inorganic nanoparticles: Common aspects and guidelines for improved nanotoxicity evaluation
    • (a) Soenen, S.; Rivera-Gil, P.; Montenegro, J.; Parak, W.; De Smedt, S.; Braeckmans, K. Cellular toxicity of inorganic nanoparticles: Common aspects and guidelines for improved nanotoxicity evaluation. Nanotoday, 2011, 6, 446-465;
    • (2011) Nanotoday , vol.6 , pp. 446-465
    • Soenen, S.1    Rivera-Gil, P.2    Montenegro, J.3    Parak, W.4    De Smedt, S.5    Braeckmans, K.6
  • 94
    • 77954959508 scopus 로고    scopus 로고
    • Nanoparticle cytotoxicity depends on intracellular solubility: Comparison of stabilized copper metal and degradable copper oxide nanoparticles
    • (b) Studer, A. M.; Limbach, L. K.; Van Duc, L.; Krumeich, F.; Athanassiou, E. K.; Gerber, L. C.; Moch, H.; Stark, W. J. Nanoparticle cytotoxicity depends on intracellular solubility: comparison of stabilized copper metal and degradable copper oxide nanoparticles. Toxicol. Lett. 2010, 197, 169-174.
    • (2010) Toxicol. Lett. , vol.197 , pp. 169-174
    • Studer, A.M.1    Limbach, L.K.2    Van Duc, L.3    Krumeich, F.4    Athanassiou, E.K.5    Gerber, L.C.6    Moch, H.7    Stark, W.J.8
  • 95
    • 58149084243 scopus 로고    scopus 로고
    • Role for nanomaterial-autophagy interaction in neurodegenerative disease
    • Stern, S. T.; Johnson, D. N. Role for nanomaterial-autophagy interaction in neurodegenerative disease. Autophagy, 2008, 4, 1097-1100.
    • (2008) Autophagy , vol.4 , pp. 1097-1100
    • Stern, S.T.1    Johnson, D.N.2
  • 96
    • 84862197399 scopus 로고    scopus 로고
    • Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity
    • Stern, S. T.; Adiseshaiah, P. P.; Crist, R. M. Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity. Part. Fibre Toxicol., 2012, 9, 20.
    • (2012) Part. Fibre Toxicol. , vol.9 , pp. 20
    • Stern, S.T.1    Adiseshaiah, P.P.2    Crist, R.M.3
  • 97
    • 84855945488 scopus 로고    scopus 로고
    • Induction of oxidative stress, lysosome activation and autophagy by nanoparticles in human brain-derived endothelial cells
    • (a) Halamoda Kenzaoui, B.; Chapuis Bernasconi, C.; Guney-Ayra, S.; Juillerat-Jeanneret, L. Induction of oxidative stress, lysosome activation and autophagy by nanoparticles in human brain-derived endothelial cells. Biochem. J., 2012, 441, 813-821;
    • (2012) Biochem. J. , vol.441 , pp. 813-821
    • Halamoda Kenzaoui, B.1    Chapuis Bernasconi, C.2    Guney-Ayra, S.3    Juillerat-Jeanneret, L.4
  • 99
    • 81855171999 scopus 로고    scopus 로고
    • Gold nanoparticles induce autophagosome accumulation through sizedependent nanoparticle uptake and lysosome impairment
    • (c) Ma, X.; Wu, Y.; Jin, S.; Tian, Y.; Zhang, X.; Zhao, Y.; Yu, L.; Liang, X. J. Gold nanoparticles induce autophagosome accumulation through sizedependent nanoparticle uptake and lysosome impairment. ACS Nano, 2011, 5, 8629-8639;
    • (2011) ACS Nano , vol.5 , pp. 8629-8639
    • Ma, X.1    Wu, Y.2    Jin, S.3    Tian, Y.4    Zhang, X.5    Zhao, Y.6    Yu, L.7    Liang, X.J.8
  • 100
    • 54349084577 scopus 로고    scopus 로고
    • Induction of autophagy in porcine kidney cells by quantum dots: A common cellular response to nanomaterials?
    • (d) Stern, S. T.; Zolnik, B. S.; McLeland, C. B.; Clogston, J.; Zheng, J.; McNeil, S. E. Induction of autophagy in porcine kidney cells by quantum dots: a common cellular response to nanomaterials? Toxicol. Sci., 2008, 106, 140-152;
    • (2008) Toxicol. Sci. , vol.106 , pp. 140-152
    • Stern, S.T.1    Zolnik, B.S.2    McLeland, C.B.3    Clogston, J.4    Zheng, J.5    McNeil, S.E.6
  • 101
    • 33744786768 scopus 로고    scopus 로고
    • Cytotoxicity of water-soluble fullerene in vascular endothelial cells
    • (e) Yamawaki, H.; Iwai, N. Cytotoxicity of water-soluble fullerene in vascular endothelial cells. Am. J. Physiol. Cell. Physiol., 2006, 290, C1495-1502;
    • (2006) Am. J. Physiol. Cell. Physiol. , vol.290
    • Yamawaki, H.1    Iwai, N.2
  • 102
    • 73449138745 scopus 로고    scopus 로고
    • Autophagymediated chemosensitization in cancer cells by fullerene C60 nanocrystal
    • (f) Zhang, Q.; Yang, W.; Man, N.; Zheng, F.; Shen, Y.; Sun, K.; Li, Y.; Wen, L. P. Autophagymediated chemosensitization in cancer cells by fullerene C60 nanocrystal. Autophagy, 2009, 5, 1107-1117.
    • (2009) Autophagy , vol.5 , pp. 1107-1117
    • Zhang, Q.1    Yang, W.2    Man, N.3    Zheng, F.4    Shen, Y.5    Sun, K.6    Li, Y.7    Wen, L.P.8
  • 104
    • 77957227472 scopus 로고    scopus 로고
    • Fullerenol cytotoxicity in kidney cells is associated with cytoskeleton disruption, autophagic vacuole accumulation, and mitochondrial dysfunction
    • (a) Johnson-Lyles, D. N.; Peifley, K.; Lockett, S.; Neun, B. W.; Hansen, M.; Clogston, J.; Stern, S. T.; McNeil, S. E. Fullerenol cytotoxicity in kidney cells is associated with cytoskeleton disruption, autophagic vacuole accumulation, and mitochondrial dysfunction. Toxicol. Appl. Pharmacol., 2010, 248, 249-258;
    • (2010) Toxicol. Appl. Pharmacol. , vol.248 , pp. 249-258
    • Johnson-Lyles, D.N.1    Peifley, K.2    Lockett, S.3    Neun, B.W.4    Hansen, M.5    Clogston, J.6    Stern, S.T.7    McNeil, S.E.8
  • 105
    • 77953811755 scopus 로고    scopus 로고
    • Autophagy and oxidative stress associated with gold nanoparticles
    • (b) Li, J. J.; Hartono, D.; Ong, C. N.; Bay, B. H.; Yung, L. Y. Autophagy and oxidative stress associated with gold nanoparticles. Biomaterials, 2010, 31, 5996-6003;
    • (2010) Biomaterials , vol.31 , pp. 5996-6003
    • Li, J.J.1    Hartono, D.2    Ong, C.N.3    Bay, B.H.4    Yung, L.Y.5
  • 107
    • 73849095460 scopus 로고    scopus 로고
    • Rare earth oxide nanocrystals induce autophagy in HeLa cells
    • (d) Yu, L.; Lu, Y.; Man, N.; Yu, S. H.; Wen, L. P. Rare earth oxide nanocrystals induce autophagy in HeLa cells. Small, 2009, 5, 2784-2787.
    • (2009) Small , vol.5 , pp. 2784-2787
    • Yu, L.1    Lu, Y.2    Man, N.3    Yu, S.H.4    Wen, L.P.5
  • 108
    • 78650102904 scopus 로고    scopus 로고
    • C60(Nd) nanoparticles enhance chemotherapeutic susceptibility of cancer cells by modulation of autophagy
    • Wei, P.; Zhang, L.; Lu, Y.; Man, N.; Wen, L. C60(Nd) nanoparticles enhance chemotherapeutic susceptibility of cancer cells by modulation of autophagy. Nanotechnology, 2010, 21, 495101.
    • (2010) Nanotechnology , vol.21 , pp. 495101
    • Wei, P.1    Zhang, L.2    Lu, Y.3    Man, N.4    Wen, L.5
  • 109
    • 25844493714 scopus 로고    scopus 로고
    • Nano neodymium oxide induces massive vacuolization and autophagic cell death in nonsmall cell lung cancer NCI-H460 cells
    • Chen, Y.; Yang, L.; Feng, C.; Wen, L. P. Nano neodymium oxide induces massive vacuolization and autophagic cell death in nonsmall cell lung cancer NCI-H460 cells. Biochem. Biophys. Res. Commun., 2005, 337, 52-60.
    • (2005) Biochem. Biophys. Res. Commun. , vol.337 , pp. 52-60
    • Chen, Y.1    Yang, L.2    Feng, C.3    Wen, L.P.4
  • 110
    • 41549129392 scopus 로고    scopus 로고
    • The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles
    • Li, N.; Xia, T.; Nel, A. E. The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles. Free Radical Biol. Med., 2008, 44, 1689-1699.
    • (2008) Free Radical Biol. Med. , vol.44 , pp. 1689-1699
    • Li, N.1    Xia, T.2    Nel, A.E.3
  • 111
    • 77955562565 scopus 로고    scopus 로고
    • Protein-nanoparticle interaction: Identification of the ubiquitin-gold nanoparticle interaction site
    • Calzolai, L.; Franchini, F.; Gilliland, D.; Rossi, F. Protein-nanoparticle interaction: identification of the ubiquitin-gold nanoparticle interaction site. Nano Lett., 2010, 10, 3101-3105.
    • (2010) Nano Lett. , vol.10 , pp. 3101-3105
    • Calzolai, L.1    Franchini, F.2    Gilliland, D.3    Rossi, F.4
  • 112
    • 27744516368 scopus 로고    scopus 로고
    • Unmodified cadmium telluride quantum dots induce reactive oxygen species formation leading to multiple organelle damage and cell death
    • (a) Lovric, J.; Cho, S. J.; Winnik, F. M.; Maysinger, D. Unmodified cadmium telluride quantum dots induce reactive oxygen species formation leading to multiple organelle damage and cell death. Chem. Biol., 2005, 12, 1227-1234;
    • (2005) Chem. Biol. , vol.12 , pp. 1227-1234
    • Lovric, J.1    Cho, S.J.2    Winnik, F.M.3    Maysinger, D.4
  • 113
    • 55849109629 scopus 로고    scopus 로고
    • Manufactured aluminum oxide nanoparticles decrease expression of tight junction proteins in brain vasculature
    • (b) Chen, L.; Yokel, R. A.; Hennig, B.; Toborek, M. Manufactured aluminum oxide nanoparticles decrease expression of tight junction proteins in brain vasculature. J. Neuroimmune Pharmacol., 2008, 3, 286-295;
    • (2008) J. Neuroimmune Pharmacol. , vol.3 , pp. 286-295
    • Chen, L.1    Yokel, R.A.2    Hennig, B.3    Toborek, M.4
  • 116
    • 33845410139 scopus 로고    scopus 로고
    • Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants
    • (e) Pulskamp, K.; Diabate, S.; Krug, H. F. Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants. Toxicol. Lett., 2007, 168, 58-74.
    • (2007) Toxicol. Lett. , vol.168 , pp. 58-74
    • Pulskamp, K.1    Diabate, S.2    Krug, H.F.3
  • 118
    • 63449105617 scopus 로고    scopus 로고
    • Cytotoxicity and genotoxicity of silver nanoparticles in human cells
    • (a) AshaRani, P. V.; Low Kah Mun, G.; Hande, M. P.; Valiyaveettil, S. Cytotoxicity and genotoxicity of silver nanoparticles in human cells. ACS Nano, 2009, 3, 279-290;
    • (2009) ACS Nano , vol.3 , pp. 279-290
    • Asharani, P.V.1    Low Kah Mun, G.2    Hande, M.P.3    Valiyaveettil, S.4
  • 119
    • 79651472432 scopus 로고    scopus 로고
    • Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis
    • (b) Piao, M. J.; Kang, K. A.; Lee, I. K.; Kim, H. S.; Kim, S.; Choi, J. Y.; Choi, J.; Hyun, J. W. Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis. Toxicol. Lett., 2011, 201, 92-100.
    • (2011) Toxicol. Lett. , vol.201 , pp. 92-100
    • Piao, M.J.1    Kang, K.A.2    Lee, I.K.3    Kim, H.S.4    Kim, S.5    Choi, J.Y.6    Choi, J.7    Hyun, J.W.8
  • 121
    • 79952117910 scopus 로고    scopus 로고
    • Treatment of human astrocytoma U87 cells with silicon dioxide nanoparticles lowers their survival and alters their expression of mitochondrial and cell signaling proteins
    • (a) Lai, J. C.; Ananthakrishnan, G.; Jandhyam, S.; Dukhande, V. V.; Bhushan, A.; Gokhale, M.; Daniels, C. K.; Leung, S. W. Treatment of human astrocytoma U87 cells with silicon dioxide nanoparticles lowers their survival and alters their expression of mitochondrial and cell signaling proteins. Int. J. Nanomedicine, 2010, 5, 715-723;
    • (2010) Int. J. Nanomedicine , vol.5 , pp. 715-723
    • Lai, J.C.1    Ananthakrishnan, G.2    Jandhyam, S.3    Dukhande, V.V.4    Bhushan, A.5    Gokhale, M.6    Daniels, C.K.7    Leung, S.W.8
  • 122
    • 69449091125 scopus 로고    scopus 로고
    • Nanosized polyamidoamine (PAMAM) dendrimer-induced apoptosis mediated by mitochondrial dysfunction
    • (b) Lee, J. H.; Cha, K. E.; Kim, M. S.; Hong, H. W.; Chung, D. J.; Ryu, G.; Myung, H. Nanosized polyamidoamine (PAMAM) dendrimer-induced apoptosis mediated by mitochondrial dysfunction. Toxicol. Lett., 2009, 190, 202-207.
    • (2009) Toxicol. Lett. , vol.190 , pp. 202-207
    • Lee, J.H.1    Cha, K.E.2    Kim, M.S.3    Hong, H.W.4    Chung, D.J.5    Ryu, G.6    Myung, H.7
  • 125
    • 83555175982 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress signaling is involved in silver nanoparticles-induced apoptosis
    • (a) Zhang, R.; Piao, M. J.; Kim, K. C.; Kim, A. D.; Choi, J. Y.; Choi, J.; Hyun, J. W. Endoplasmic reticulum stress signaling is involved in silver nanoparticles-induced apoptosis. Int J Biochem Cell Biol., 2012, 44, 224-232;
    • (2012) Int J Biochem Cell Biol. , vol.44 , pp. 224-232
    • Zhang, R.1    Piao, M.J.2    Kim, K.C.3    Kim, A.D.4    Choi, J.Y.5    Choi, J.6    Hyun, J.W.7
  • 126
    • 84857503516 scopus 로고    scopus 로고
    • Silica nanoparticles and silver-doped silica nanoparticles induce endoplasmatic reticulum stress response and alter cytochrome P4501A activity
    • (b) Christen, V.; Fent, K., Silica nanoparticles and silver-doped silica nanoparticles induce endoplasmatic reticulum stress response and alter cytochrome P4501A activity. Chemosphere, 2012, 87, 423-434.
    • (2012) Chemosphere , vol.87 , pp. 423-434
    • Christen, V.1    Fent, K.2
  • 127
    • 84862926217 scopus 로고    scopus 로고
    • Study on the visiblelight-induced photokilling effect of nitrogen-doped TiO2 nanoparticles on cancer cells
    • (a) Li, Z.; Mi, L.; Wang, P. N.; Chen, J. Y. Study on the visiblelight-induced photokilling effect of nitrogen-doped TiO2 nanoparticles on cancer cells. Nanoscale Res. Lett., 2011, 6, 356;
    • (2011) Nanoscale Res. Lett. , vol.6 , pp. 356
    • Li, Z.1    Mi, L.2    Wang, P.N.3    Chen, J.Y.4
  • 129
    • 81055156832 scopus 로고    scopus 로고
    • Genotoxic effects of silver nanoparticles stimulated by oxidative stress in human normal bronchial epithelial (BEAS-2B) cells
    • (a) Kim, H. R.; Kim, M. J.; Lee, S. Y.; Oh, S. M.; Chung, K. H. Genotoxic effects of silver nanoparticles stimulated by oxidative stress in human normal bronchial epithelial (BEAS-2B) cells. Mutat. Res., 2011, 726, 129-135;
    • (2011) Mutat. Res. , vol.726 , pp. 129-135
    • Kim, H.R.1    Kim, M.J.2    Lee, S.Y.3    Oh, S.M.4    Chung, K.H.5
  • 130
    • 79957731160 scopus 로고    scopus 로고
    • Zinc oxide nanoparticles induce oxidative stress and genotoxicity in human liver cells (HepG2)
    • (b) Sharma, V.; Anderson, D.; Dhawan, A. Zinc oxide nanoparticles induce oxidative stress and genotoxicity in human liver cells (HepG2). J. Biomed. Nanotechnol., 2011, 7, 98-99;
    • (2011) J. Biomed. Nanotechnol. , vol.7 , pp. 98-99
    • Sharma, V.1    Anderson, D.2    Dhawan, A.3
  • 131
    • 78650519473 scopus 로고    scopus 로고
    • ROS-mediated genotoxicity induced by titanium dioxide nanoparticles in human epidermal cells
    • (c) Shukla, R. K.; Sharma, V.; Pandey, A. K.; Singh, S.; Sultana, S.; Dhawan, A. ROS-mediated genotoxicity induced by titanium dioxide nanoparticles in human epidermal cells. Toxicol. in vitro, 2011, 25, 231-241;
    • (2011) Toxicol. in Vitro , vol.25 , pp. 231-24
    • Shukla, R.K.1    Sharma, V.2    Pandey, A.K.3    Singh, S.4    Sultana, S.5    Dhawan, A.6
  • 132
    • 84863951606 scopus 로고    scopus 로고
    • CuO nanoparticle interaction with human epithelial cells: Cellular uptake, location, export, and genotoxicity
    • (d) Wang, Z.; Li, N.; Zhao, J.; White, J. C.; Qu, P.; Xing, B. CuO nanoparticle interaction with human epithelial cells: cellular uptake, location, export, and genotoxicity. Chem. Res. Toxicol., 2012, 25, 1512-1521.
    • (2012) Chem. Res. Toxicol. , vol.25 , pp. 1512-1521
    • Wang, Z.1    Li, N.2    Zhao, J.3    White, J.C.4    Qu, P.5    Xing, B.6
  • 134
    • 0142219722 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of cadmium carcinogenesis
    • Waisberg, M.; Joseph, P.; Hale, B.; Beyersmann, D. Molecular and cellular mechanisms of cadmium carcinogenesis. Toxicology, 2003, 192, 95-117.
    • (2003) Toxicology , vol.192 , pp. 95-117
    • Waisberg, M.1    Joseph, P.2    Hale, B.3    Beyersmann, D.4
  • 135
    • 84870312653 scopus 로고    scopus 로고
    • The cadmium-mercaptoacetic acid complex contributes to the genotoxicity of mercaptoacetic acid-coated CdSe-core quantum dots
    • Tang, W.; Fan, J.; He, Y.; Huang, B.; Liu, H.; Pang, D.; Xie, Z. The cadmium-mercaptoacetic acid complex contributes to the genotoxicity of mercaptoacetic acid-coated CdSe-core quantum dots. Int. J. Nanomedicine, 2012, 7, 2631-2640.
    • (2012) Int. J. Nanomedicine , vol.7 , pp. 2631-2640
    • Tang, W.1    Fan, J.2    He, Y.3    Huang, B.4    Liu, H.5    Pang, D.6    Xie, Z.7
  • 136
    • 15044357362 scopus 로고    scopus 로고
    • Formation of nucleoplasmic protein aggregates impairs nuclear function in response to SiO2 nanoparticles
    • Chen, M.; von Mikecz, A. Formation of nucleoplasmic protein aggregates impairs nuclear function in response to SiO2 nanoparticles. Exp. Cell Res., 2005, 305, 51-62.
    • (2005) Exp. Cell Res. , vol.305 , pp. 51-62
    • Chen, M.1    Von Mikecz, A.2
  • 139
    • 77956897767 scopus 로고    scopus 로고
    • Genotoxicity and cytotoxicity of multi-wall carbon nanotubes in cultured Chinese hamster lung cells in comparison with chrysotile A fibers
    • Asakura, M.; Sasaki, T.; Sugiyama, T.; Takaya, M.; Koda, S.; Nagano, K.; Arito, H.; Fukushima, S. Genotoxicity and cytotoxicity of multi-wall carbon nanotubes in cultured Chinese hamster lung cells in comparison with chrysotile A fibers. J. Occup. Health, 2010, 52, 155-166.
    • (2010) J. Occup. Health , vol.52 , pp. 155-166
    • Asakura, M.1    Sasaki, T.2    Sugiyama, T.3    Takaya, M.4    Koda, S.5    Nagano, K.6    Arito, H.7    Fukushima, S.8
  • 142
    • 84887889748 scopus 로고    scopus 로고
    • Nanoparticle Technology as a Double-Edged Sword: Cytotoxic, Genotoxic and Epigenetic Effects on Living Cells
    • Mytych, J.; Maciej, W. Nanoparticle Technology as a Double-Edged Sword: Cytotoxic, Genotoxic and Epigenetic Effects on Living Cells. J. Biomater. Nanobiotechnol., 2013, 4, 53-63.
    • (2013) J. Biomater. Nanobiotechnol. , vol.4 , pp. 53-63
    • Mytych, J.1    Maciej, W.2
  • 143
    • 58149289831 scopus 로고    scopus 로고
    • Alternative modes of binding of recombinant human histone dea-cetylase 8 to colloidal gold nanoparticles
    • (a) Sule, N.; Singh, R.; Srivastava, D. Alternative Modes of Binding of Recombinant Human Histone Dea-cetylase 8 to Colloidal Gold Nanoparticles. J. Biomed. Nanotechnol., 2008, 4, 463-468;
    • (2008) J. Biomed. Nanotechnol. , vol.4 , pp. 463-468
    • Sule, N.1    Singh, R.2    Srivastava, D.3
  • 145
    • 39749107963 scopus 로고    scopus 로고
    • Protein-nanoparticle interactions
    • Lynch, I.; Dawson, K. A. Protein-nanoparticle interactions. Nanotoday, 2008, 3, 40-47.
    • (2008) Nanotoday , vol.3 , pp. 40-47
    • Lynch, I.1    Dawson, K.A.2
  • 146
    • 67649588695 scopus 로고    scopus 로고
    • Nanomaterials-acetylcholinesterase enzyme matrices for organophosphorus pesticides electrochemical sensors: A review
    • Periasamy, A. P.; Umasankar, Y.; Chen, S. M., Nanomaterials- acetylcholinesterase enzyme matrices for organophosphorus pesticides electrochemical sensors: a review. Sensors (Basel), 2009, 9, 4034-4055.
    • (2009) Sensors (Basel) , vol.9 , pp. 4034-4055
    • Periasamy, A.P.1    Umasankar, Y.2    Chen, S.M.3
  • 147
    • 0033136579 scopus 로고    scopus 로고
    • Molecular chaperone-like activity of hydrogel nanoparticles of hydrophobized pullulan: Thermal stabilization with refolding of carbonic anhydrase B
    • Akiyoshi, K.; Sasaki, Y.; Sunamoto, J. Molecular chaperone-like activity of hydrogel nanoparticles of hydrophobized pullulan: thermal stabilization with refolding of carbonic anhydrase B. Bioconjug. Chem., 1999, 10, 321-324.
    • (1999) Bioconjug. Chem. , vol.10 , pp. 321-324
    • Akiyoshi, K.1    Sasaki, Y.2    Sunamoto, J.3
  • 148
    • 65149105929 scopus 로고    scopus 로고
    • Nanoparticles of unmodified titanium dioxide facilitate protein refolding
    • Raghava, S.; Singh, P.; Rao, A.; Dutta, V.; Gupta, M. Nanoparticles of unmodified titanium dioxide facilitate protein refolding. J. Mater. Chem., 2009, 19, 2830-2834.
    • (2009) J. Mater. Chem. , vol.19 , pp. 2830-2834
    • Raghava, S.1    Singh, P.2    Rao, A.3    Dutta, V.4    Gupta, M.5
  • 150
    • 33644793287 scopus 로고    scopus 로고
    • Binding between particles and proteins in extracts: Implications for microrheology and toxicity
    • Ehrenberg, M.; McGrath, J. L. Binding between particles and proteins in extracts: implications for microrheology and toxicity. Acta Biomater., 2005, 1, 305-315.
    • (2005) Acta Biomater. , vol.1 , pp. 305-315
    • Ehrenberg, M.1    McGrath, J.L.2
  • 151
    • 78650140176 scopus 로고    scopus 로고
    • Carbon nanotubes reorganize actin structures in cells and ex vivo
    • Holt, B. D.; Short, P. A.; Rape, A. D.; Wang, Y. L.; Islam, M. F.; Dahl, K. N. Carbon nanotubes reorganize actin structures in cells and ex vivo. ACS Nano, 2010, 4, 4872-4878.
    • (2010) ACS Nano , vol.4 , pp. 4872-4878
    • Holt, B.D.1    Short, P.A.2    Rape, A.D.3    Wang, Y.L.4    Islam, M.F.5    Dahl, K.N.6
  • 152
    • 0343907224 scopus 로고    scopus 로고
    • Adsorption to silica nanoparticles of human carbonic anhydrase II and truncated forms induce a molten-globule-like structure
    • Billsten, P.; Freskgard, P. O.; Carlsson, U.; Jonsson, B. H.; Elwing, H. Adsorption to silica nanoparticles of human carbonic anhydrase II and truncated forms induce a molten-globule-like structure. FEBS Lett., 1997, 402, 67-72.
    • (1997) FEBS Lett. , vol.402 , pp. 67-72
    • Billsten, P.1    Freskgard, P.O.2    Carlsson, U.3    Jonsson, B.H.4    Elwing, H.5
  • 156
    • 84861158206 scopus 로고    scopus 로고
    • Fullerene C60 prevents neurotoxicity induced by intrahippocampal microinjection of amyloid-beta peptide
    • (a) Makarova, E. G.; Gordon, R. Y.; Podolski, I. Y. Fullerene C60 prevents neurotoxicity induced by intrahippocampal microinjection of amyloid-beta peptide. J. Nanosci. Nanotechnol., 2012, 12, 119-126;
    • (2012) J. Nanosci. Nanotechnol. , vol.12 , pp. 119-126
    • Makarova, E.G.1    Gordon, R.Y.2    Podolski, I.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.