Oxidative stress, calcium homeostasis, and altered gene expression in human lung epithelial cells exposed to ZnO nanoparticles

Toxicology in Vitro

Volumn 24, Issue 1, 2010, Pages 45-55

  Huang, Chuan Chin ^a   Aronstam, Robert S ^a   Chen, Da Ren ^b   Huang, Yue Wern ^a  

^a MISSOURI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (United States)

^b WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

Author keywords

Calcium modulation; Cytotoxicity; Gene expression; Nanoparticles; Oxidative stress; ZnO

Indexed keywords

ACETYLCYSTEINE; ALBUMIN; ALDEHYDE OXIDASE; APOLIPOPROTEIN E; ARACHIDONATE 12 LIPOXYGENASE; CALCIUM; CATALASE; CYTOGLOBIN; DIACYLGLYCEROL KINASE; EPOXIDE HYDROLASE; GLUTAREDOXIN; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE SYNTHASE; GLUTATHIONE TRANSFERASE; LACTATE DEHYDROGENASE; LACTOPEROXIDASE; MANNOSE BINDING LECTIN; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; NANOPARTICLE; NIFEDIPINE; PEROXIREDOXIN; PEROXIREDOXIN 3; PRION PROTEIN; PROTEIN BCL 2; PROTEIN BNIP3; RNA BINDING PROTEIN; THIOREDOXIN REDUCTASE 1; UNINDEXED DRUG; ZINC OXIDE;

APOPTOSIS; ARTICLE; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; ENZYME RELEASE; GENE EXPRESSION; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; MEMBRANE DAMAGE; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; TIME; UNINDEXED SEQUENCE;

ACETYLCYSTEINE; CALCIUM; CALCIUM CHANNEL BLOCKERS; CELL LINE; CELL MEMBRANE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; FREE RADICAL SCAVENGERS; GENE EXPRESSION; HOMEOSTASIS; HUMANS; L-LACTATE DEHYDROGENASE; LUNG; NANOPARTICLES; NIFEDIPINE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; ZINC OXIDE;

EID: 72049093217     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.09.007     Document Type: Article

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