DNA damage leads to progressive replicative decline but extends the life span of long-lived mutant animals

Cell Death and Differentiation

Volumn 20, Issue 12, 2013, Pages 1709-1718

  Lans, H ^a   Lindvall, J M ^b,c   Thijssen, K ^a   Karambelas, A E ^a,d   Cupac, D ^a,e   Fensgard O ^b   Jansen, G ^a   Hoeijmakers, J H J ^a   Nilsen, H ^b   Vermeulen, W ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF OSLO   (Norway)

^c KAROLINSKA INSTITUTE   (Sweden)

^d UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^e LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

aging; C. elegans; DNA damage; DNA repair; DNA damage response; Nucleotide excision repair

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CAENORHABDITIS ELEGANS; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DNA CROSS LINKING; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; GROWTH, DEVELOPMENT AND AGING; IONIZING RADIATION; LIFESPAN; MUTANT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; STRESS;

ANIMALIA; CAENORHABDITIS ELEGANS;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; HUMANS; LONGEVITY; MUTATION; PRINCIPAL COMPONENT ANALYSIS; STRESS, PHYSIOLOGICAL;

EID: 84887626853     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2013.126     Document Type: Article

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