Oxidative stress-related PMK-1 P38 MAPK activation as a mechanism for toxicity of silver nanoparticles to reproduction in the nematode Caenorhabditis elegans

Environmental Toxicology and Chemistry

Volumn 31, Issue 3, 2012, Pages 585-592

  Lim, Dongyoung ^a   Roh, Ji Yeon ^a   Eom, Hyun Jeong ^a   Choi, Jeong Yun ^b   Hyun, Jinwon ^c   Choi, Jinhee ^a  

^a University of Seoul   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

^c Jeju National University   (South Korea)

Author keywords

Caenorhabditis elegans; Mitogen activated protein kinase; Oxidative stress; Reproduction; Silver nanoparticles

Indexed keywords

CAENORHABDITIS ELEGANS; ELEGANS; GLUTATHIONE-S-TRANSFERASE; HYPOXIA-INDUCIBLE FACTORS; MITOGEN ACTIVATED PROTEIN KINASE; P38 MAPK; P38 MITOGEN-ACTIVATED PROTEIN KINASE; PROTEIN EXPRESSIONS; REACTIVE OXYGEN SPECIES; REPRODUCTION; REPRODUCTIVE POTENTIAL; SIGNALING PATHWAYS; SILVER NANOPARTICLES; WILD TYPES;

ENZYME ACTIVITY; GENES; NANOPARTICLES; OXIDATIVE STRESS; TOXICITY; TRANSCRIPTION FACTORS;

SILVER;

ACETYLCYSTEINE; GLUTATHIONE TRANSFERASE; HYPOXIA INDUCIBLE FACTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; SILVER NANOPARTICLE; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR NRF2;

DEFENSE MECHANISM; ENZYME ACTIVITY; GENE EXPRESSION; MUTATION; NANOTECHNOLOGY; NEMATODE; PARTICLE SIZE; PROTEIN; REPRODUCTIVE POTENTIAL; SILVER; TOXICOLOGY;

ARTICLE; CAENORHABDITIS ELEGANS; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION; HOST RESISTANCE; NONHUMAN; OXIDATIVE STRESS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REPRODUCTION; REPRODUCTION TOXICITY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TOXICITY;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; GLUTATHIONE TRANSFERASE; HYPOXIA-INDUCIBLE FACTOR 1; METAL NANOPARTICLES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASES; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; REPRODUCTION; SIGNAL TRANSDUCTION; SILVER; TRANSCRIPTION FACTORS;

CAENORHABDITIS ELEGANS;

EID: 84862793246     PISSN: 07307268     EISSN: 15528618     Source Type: Journal    
DOI: 10.1002/etc.1706     Document Type: Article

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