Homologous recombination is required for genome stability in the absence of DOG-1 in Caenorhabditis elegans

Genetics

Volumn 173, Issue 2, 2006, Pages 697-708

  Youds, Jillian L ^a   O'Neil, Nigel J ^a   Rose, Ann M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 ASSOCIATED RING DOMAIN PROTEIN 1; FUNGAL PROTEIN; PROTEIN DOG 1; PROTEIN HIM 6; RAD51 PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; EXCISION REPAIR; GENE DELETION; GENE FUNCTION; GENOMIC INSTABILITY; GERM LINE; HOMOLOGOUS RECOMBINATION; MITOSIS RATE; MUTAGENIC ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; STRESS; STRUCTURAL GENE;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL NUCLEUS; DNA HELICASES; DNA REPAIR; DNA REPLICATION; DNA, HELMINTH; DNA-DIRECTED DNA POLYMERASE; GENES, HELMINTH; GENOME, HELMINTH; GENOMIC INSTABILITY; MITOSIS; MODELS, GENETIC; MUTATION; RAD51 RECOMBINASE; RECOMBINATION, GENETIC; RNA INTERFERENCE; SEQUENCE DELETION; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES;

CAENORHABDITIS ELEGANS; CANIS FAMILIARIS;

EID: 33745407668     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.106.056879     Document Type: Article

References (73)

1. AHMED, S., and J. HODGKIN, 2000 MRT-2 checkpoint protein is required for germline immortality and telomere replication in C. elegans. Nature 403(6766): 159-164.
2. AHMED, S., A. ALPI, M. O. HENGARTNER and A. GARTNER, 2001 C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein. Curr. Biol. 11: 1934-1944.
3. ARTHANARI, H., and P. H. BOLTON, 2001 Functional and dysfunctional roles of quadruplex DNA in cells. Chem. Biol. 8: 221-230.
4. BARBOUR, L., and W. XIAO, 2003 Regulation of alternative replication bypass pathways at stalled replication forks and its effects on genome stability: a yeast model. Mutat. Res. 532: 137-155.
5. BERGOGLIO, V., C. BAVOUX, V. VERBIEST, J. S. HOFFMANN and C. CAZAUX, 2002 Localisation of human DNA polymerase kappa to replication foci. J. Cell Sci. 115: 4413-4418.
6. BJERGBAEK, L., J. A. COBB, M. TSAI-PFLUGFELDER and S. M. GASSER, 2005 Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance. EMBO J. 24: 405-417.
7. BOULTON, S. J., J. S. MARTIN, J. POLANOWSKA, D. E. HILL, A. GARTNER et al., 2004 BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans. Curr. Biol. 14: 33-39.
8. BRENNER, S., 1974 The genetics of Caenorhabditis elegans. Genetics 77: 71-94.
9. BROOMFIELD, S., T. HRYCIW and W. XIAO, 2001 DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae. Mutat. Res. 486: 167-184.
10. CHAVEZ, S., and A. AGUILERA, 1997 The yeast HPR1 gene has a functional role in transcriptional elongation that uncovers a novel source of genome instability. Genes Dev. 11: 3459-3470.
11. CHEUNG, I., M. SCHERTZER, A. ROSE and P. M. LANSDORP, 2002 Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA. Nat. Genet. 31: 405-409.
12. DALEY, J. M., P. L. PALMBOS, D. WU and T. E. WILSON, 2005 Non-homologous end joining in yeast. Annu. Rev. Genet. 39: 431-451.
13. DERRY, W. B., A. P. PUTZKE and J. H. ROTHMAN, 2001 Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance. Science 294: 591-595.
14. DING, H., M. SCHERTZER, X. WU, M. GERTSENSTEIN, S. SELIG et al., 2004 Regulation of murine telomere length by rtel: an essential gene encoding a helicase-like protein. Cell 117: 873-886.
15. DUDENHOFFER, C., G. ROHALY, K. WILL, W. DEPPERT and L. WIESMULLER, 1998 Specific mismatch recognition in heteroduplex intermediates by p53 suggests a role in fidelity control of homologous recombination. Mol. Cell. Biol. 18: 5332-5342.
16. EDENBERG, H. J., 1976 Inhibition of DNA replication by ultraviolet light. Biophys. J. 16: 849-860.
17. GARCIA-MUSE, T., and S. J. BOULTON, 2005 Distinct modes of ATR activation after replication stress and DNA double-strand breaks in Caenorhabditis elegans. EMBO J. 24: 4345-4355.
18. GARTNER, A., S. MILSTEIN, S. AHMED, J. HODGKIN and M. O. HENGARTNER, 2000 A conserved checkpoint pathway mediates DNA damage-induced apoptosis and cell cycle arrest in C. elegans. Mol. Cell 5: 435-443.
19. GRABOWSKI, M. M., N. SVRZIKAPA and H. A. TISSENBAUM, 2005 Bloom syndrome ortholog HIM-6 maintains genomic stability in C. elegans. Mech. Ageing Dev. 126: 1314-1321.
20. HOY, C. A., L. H. THOMPSON, C. L. MOONEY and E. P. SALAZAR, 1985 Defective DNA cross-link removal in Chinese hamster cell mutants hypersensitive to bifunctional alkylating agents. Cancer Res. 45: 1737-1743.
21. HUBER, M. D., D. C. LEE and N. MAIZELS, 2002 G4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition. Nucleic Acids Res. 30: 3954-3961.
22. HWANG, D. S., and A. KORNBERG, 1990 A novel protein binds a key origin sequence to block replication of an E. coli minichromosome. Cell 63: 325-331.
23. II, M., and S. J. BRILL, 2005 Roles of SGS1, MUS81, and RAD51 in the repair of lagging-strand replication defects in Saccharomyces cerevisiae. Curr. Genet. 48: 213-225.
24. IVANOV, E. L., and J. E. HABER, 1997 DNA repair: RAD alert. Curr. Biol. 7: R492-R495.
25. KAI, M., M. N. BODDY, P. RUSSELL and T. S. WANG, 2005 Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress. Genes Dev. 19: 919-932.
26. KANNOUCHE, P., B. C. BROUGHTON, M. VOLKER, F. HANAOKA, L. H. MULLENDERS et al., 2001 Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells. Genes Dev. 15: 158-172.
27. KANNOUCHE, P., A. R. FERNANDEZ DE HENESTROSA, B. COULL, A. E. VIDAL, C. GRAY et al., 2003 Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. EMBO J. 22: 1223-1233.
28. KAROW, J. K., A. CONSTANTINOU, J. L. LI, S. C. WEST and I. D. HICKSON, 2000 The Bloom's syndrome gene product promotes branch migration of Holliday junctions. Proc. Natl. Acad. Sci. USA 97: 6504-6508.
29. KAWAMOTO, T., K. ARAKI, E. SONODA, Y. M. YAMASHITA, K. HARADA et al., 2005 Dual roles for DNA polymerase eta in homologous DNA recombination and translesion DNA synthesis. Mol. Cell 20: 793-799.
30. KIM, Y. M., I. YANG, J. LEE and H. S. KOO, 2005 Deficiency of Bloom's syndrome protein causes hypersensitivity of C. elegans to ionizing radiation but not to UV radiation, and induces p53-dependent physiological apoptosis. Mol. Cells 20: 228-234.
31. KLEIN, H. L., 1988 Different types of recombination events are controlled by the RAD1 and RAD52 genes of Saccharomyces cerevisiae. Genetics 120: 367-377.
32. KURAOKA, I., W. R. KOBERTZ, R. R. ARIZA, M. BIGGERSTAFF, J. M. ESSIGMANN et al., 2000 Repair of an interstrand DNA cross-link initiated by ERCC1-XPF repair/recombination nuclease. J. Biol. Chem. 275: 26632-26636.
33. LEE, S. J., J. S. YOOK, S. M. HAN and H. S. KOO, 2004 A Werner syndrome protein homolog affects C. elegans development, growth rate, life span and sensitivity to DNA damage by acting at a DNA damage checkpoint. Development 131: 2565-2575.
34. LEHMANN, A. R., 2002 Replication of damaged DNA in mammalian cells: new solutions to an old problem. Mutat. Res. 509: 23-34.
35. LEVITUS, M., Q. WAISFISZ, B. C. GODTHELP, Y. DE VRIES, S. HUSSAIN et al., 2005 The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J. Nat. Genet. 37: 934-935.
36. LEVRAN, O., C. ATTWOOLL, R. T. HENRY, K. L. MILTON, K. NEVELING et al., 2005 The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia. Nat. Genet. 37: 931-933.
37. LI, X., and J. L. MANLEY, 2005 Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability. Cell 122: 365-378.
38. LIBERI, G., G. MAFFIOLETTI, C. LUCCA, I. CHIOLO, A. BARYSHNIKOVA et al., 2005 Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase. Genes Dev. 19: 339-350.
39. LUNDIN, C., N. SCHULTZ, C. ARNAUDEAU, A. MOHINDRA, L. T. HANSEN et al., 2003 RAD51 is involved in repair of damage associated with DNA replication in mammalian cells. J. Mol. Biol. 328: 521-535.
40. MCGLYNN, P., and R. G. LLOYD, 2001 Rescue of stalled replication forks by RecG: simultaneous translocation on the leading and lagging strand templates supports an active DNA unwinding model of fork reversal and Holliday junction formation. Proc. Natl. Acad. Sci. USA 98: 8227-8234.
41. MCGLYNN, P., and R. G. LLOYD, 2002 Recombinational repair and restart of damaged replication forks. Nat. Rev. Mol. Cell Biol. 3: 859-870.
42. MCLLWRAITH, M. J., A. VAISMAN, Y. LIU, E. FANNING, R. WOODGATE et al., 2005 Human DNA polymerase eta promotes DNA synthesis from strand invasion intermediates of homologous recombination. Mol. Cell 20: 783-792.
43. MICHEL, B., M. J. FLORES, E. VIGUERA, G. GROMPONE, M. SEIGNEUR et al., 2001 Rescue of arrested replication forks by homologous recombination. Proc. Natl. Acad. Sci. USA 98: 8181-8188.
44. MOHAGHEGH, P., J. K. KAROW, R. M. BROSH, JR., V. A. BOHR and I. D. HICKSON, 2001 The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases. Nucleic Acids Res. 29: 2843-2849.
45. MUKHOPADHYAY, S., D. R. CLARK, N. B. WATSON, W. ZACHARIAS and W. G. MCGREGOR, 2004 REV1 accumulates in DNA damage-induced nuclear foci in human cells and is implicated in mutagenesis by benzo[a]pyrenediolepoxide. Nucleic Acids Res. 32: 5820-5826.
46. NIEDERNHOFER, L. J., J. ESSERS, G. WEEDA, B. BEVERLOO, J. DE WIT et al., 2001 The structure-specific endonuclease Ercc1-xpf is required for targeted gene replacement in embryonic stem cells. EMBO J. 20: 6540-6549.
47. NIEDERNHOFER, L. J., H. ODIJK, M. BUDZOWSKA, E. VAN DRUNEN, A. MAAS et al., 2004 The structure-specific endonuclease Ercc1-xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks. Mol. Cell. Biol. 24: 5776-5787.
48. PARK, H. K., J. S. YOOK, H. S. KOO, I. S. CHOI and B. AHN, 2002 The Caenorhabditis elegans XPA homolog of human XPA. Mol. Cells 14: 50-55.
49. PRAKASH, S., R. E. JOHNSON and L. PRAKASH, 2005 Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function. Annu. Rev. Biochem. 74: 317-353.
50. REINKE, V., H. E. SMITH, J. NANCE, J. WANG, C. VAN DOREN et al., 2000 A global profile of germline gene expression in C. elegans. Mol. Cell 6: 605-616.
51. RINALDO, C., S. EDERLE, V. ROCCO and A. LA VOLPE, 1998 The Caenorhabditis elegans RAD51 homolog is transcribed into two alternative mRNAs potentially encoding proteins of different sizes. Mol. Gen. Genet. 260: 289-294.
52. SALEH-GOHARI, N., H. E. BRYANT, N. SCHULTZ, K. M. PARKER, T. N. CASSEL et al., 2005 Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks. Mol. Cell. Biol. 25: 7158-7169.
53. SARGENT, R. G., J. L. MESERVY, B. D. PERKINS, A. E. KILBURN, Z. INTODY et al., 2000 Role of the nucleotide excision repair gene ERCC1 in formation of recombination-dependent rearrangements in mammalian cells. Nucleic Acids Res. 28: 3771-3778.
54. SCHIESTL, R. H., and S. PRAKASH, 1988 RAD1, an excision repair gene of Saccharomyces cerevisiae, is also involved in recombination. Mol. Cell. Biol. 8: 3619-3626.
55. SCHIESTL, R. H., and S. PRAKASH, 1990 RAD10, an excision repair gene of Saccharomyces cerevisiae, is involved in the RAD1 pathway of mitotic recombination. Mol. Cell. Biol. 10: 2485-2491.
56. SCHUMACHER, B., K. HOFMANN, S. BOULTON and A. GARTNER, 2001 The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis. Curr. Biol. 11: 1722-1727.
57. SCULLY, R., J. CHEN, R. L. OCHS, K. KEEGAN, M. HOEKSTRA ET AL., 1997 Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell 90: 425-435.
58. SCULLY, R., N. PUGET and K. VLASAKOVA, 2000 DNA polymerase stalling, sister chromatid recombination and the BRCA genes. Oncogene 19: 6176-6183.
59. SENGUPTA, S., and C. C. HARRIS, 2005 p53: traffic cop at the crossroads of DNA repair and recombination. Nat. Rev. Mol. Cell Biol. 6: 44-55.
60. SENGUPTA, S., S. P. LINKE, R. PEDEUX, Q. YANG, J. FARNSWORTH et al., 2003 BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination. EMBO J. 22: 1210-1222.
61. SIMONSSON, T., 2001 G-quadruplex DNA structures - variations on a theme. Biol. Chem. 382: 621-628.
62. SUN, H., J. K. KAROW, I. D. HICKSON and N. MAIZELS, 1998 The Bloom's syndrome helicase unwinds G4 DNA. J. Biol. Chem. 273: 27587-27592.
63. TODD, A. K., M. JOHNSTON and S. NEIDLE, 2005 Highly prevalent putative quadruplex sequence motifs in human DNA. Nucleic Acids Res. 33: 2901-2907.
64. TRINH, T. Q., and R. R. SINDEN, 1991 Preferential DNA secondary structure mutagenesis in the lagging strand of replication in E. coli. Nature 352: 544-547.
65. VAN HAAFTEN, G., R. H. PLASTERK and M. TIJSTERMAN, 2004 Genomic instability and cancer: scanning the Caenorhabditis elegans genome for tumor suppressors. Oncogene 23: 8366-8375.
66. WARNER, H. R., and M. D. HOBBS, 1969 Effect of hydroxyurea on replication of bacteriophage T4 in Escherichia coli. J. Virol. 3: 331-336.
67. WEST, S. C., 2003 Molecular views of recombination proteins and their control. Nat. Rev. Mol. Cell Biol. 4: 435-445.
68. WICKY, C., A. ALPI, M. PASSANNANTE, A. ROSE, A. GARTNER et al., 2004 Multiple genetic pathways involving the Caenorhabditis elegans Bloom's syndrome genes him-6, rad-51, and top-3 are needed to maintain genome stability in the germ line. Mol. Cell. Biol. 24: 5016-5027.
69. WOODFORD, K. J., R. M. HOWELL and K. USDIN, 1994 A novel K(+)-dependent DNA synthesis arrest site in a commonly occurring sequence motif in eukaryotes. J. Biol. Chem. 269: 27029-27035.
70. WU, L., and I. D. HICKSON, 2003 The Bloom's syndrome helicase suppresses crossing over during homologous recombination. Nature 426: 870-874.
71. WU, L., S. L. DAVIES, N. C. LEVITT and I. D. HICKSON, 2001 Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51. J. Biol. Chem. 276: 19375-19381.
72. YANG, Q., R. ZHANG, X. W. WANG, E. A. SPILLARE, S. P. LINKE et al., 2002 The processing of Holliday junctions by BLM and WRN helicases is regulated by p53. J. Biol. Chem. 277: 31980-31987.
73. YUN, S., C. LIE-A-CHEONG and A. C. PORTER, 2004 Discriminatory suppression of homologous recombination by p53. Nucleic Acids Res. 32: 6479-6489.