Influence of dietary fat type on benzo(a)pyrene [B(a)P] biotransformation in a B(a)P-induced mouse model of colon cancer

Journal of Nutritional Biochemistry

Volumn 24, Issue 12, 2013, Pages 2051-2063

  Diggs, Deacqunita L ^a   Myers, Jeremy N ^a   Banks, Leah D ^a   Niaz, Mohammad S ^a   Hood, Darryl B ^a   Roberts, L Jackson ^b   Ramesh, Aramandla ^a  

^a MEHARRY MEDICAL COLLEGE   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ApcMin mouse; B(a)P DNA adducts; Benzo(a)pyrene; Biotransformation; Colon cancer; Metabolites; Polycyclic aromatic hydrocarbons

Indexed keywords

ARACHIS OIL; BENZO[A]PYRENE; COCONUT OIL; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; DRUG METABOLITE; GLUTATHIONE TRANSFERASE; POLYCYCLIC AROMATIC HYDROCARBON; SATURATED FATTY ACID; TRIOCTANOIN; UNSATURATED FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; CANCER GROWTH; COLON CANCER; COLON CARCINOGENESIS; COLON POLYPOSIS; CONTROLLED STUDY; DETOXIFICATION; DNA ADDUCT; DNA ISOLATION; ENZYME ACTIVITY; FAT INTAKE; FEEDING; GENE EXPRESSION; LIVER CARCINOGENESIS; MALE; METABOLIC ACTIVATION; METABOLITE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; RNA ISOLATION; THIN LAYER CHROMATOGRAPHY; WESTERN BLOTTING;

APC(MIN) MOUSE; B(A)P-DNA ADDUCTS; BENZO(A)PYRENE; BIOTRANSFORMATION; COLON CANCER; METABOLITES; POLYCYCLIC AROMATIC HYDROCARBONS;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BENZO(A)PYRENE; BIOTRANSFORMATION; CARCINOGENS; CHROMATOGRAPHY, THIN LAYER; COLON; COLONIC NEOPLASMS; DIETARY FATS; DISEASE MODELS, ANIMAL; DNA ADDUCTS; LIVER; MALE; MICE;

EID: 84887511865     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2013.07.006     Document Type: Article

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