Effect of dietary fat on metabolism and DNA adduct formation after acute oral exposure of F-344 rats to fluoranthene

Journal of Nutritional Biochemistry

Volumn 18, Issue 4, 2007, Pages 236-249

  Walker, Stormy A ^a   Addai, Amma B ^a   Mathis, Malcolm ^a   Ramesh, Aramandla ^a  

^a MEHARRY MEDICAL COLLEGE   (United States)

Author keywords

Dietary fat; Fluoranthene; Fluoranthene DNA adducts; Metabolism; Polycyclic aromatic hydrocarbons

Indexed keywords

ARACHIS OIL; COCONUT OIL; CORN OIL; DNA; FLUORANTHENE;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; CONTROLLED STUDY; DNA DETERMINATION; FAT INTAKE; FECES ANALYSIS; FEEDING; LIPID METABOLISM; LIVER; LUNG; MALE; NONHUMAN; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SMALL INTESTINE; TESTIS; URINE;

ANIMALS; DIETARY FATS; DIETARY FATS, UNSATURATED; DNA ADDUCTS; FLUORENES; JEJUNUM; LIVER; LUNG; MALE; RATS; RATS, INBRED F344; TESTIS; TISSUE DISTRIBUTION;

ARACHIS HYPOGAEA; RATTUS; ZEA MAYS;

EID: 33847646383     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2006.04.001     Document Type: Article

References (52)

1. Hill M.J. Diet and cancer: a review of scientific evidence. Eur J Cancer Prev 4 Suppl 2 (1995) 3-42
2. Woutersen R.A., Appel M.J., van Garderen-Hoetmer A., and Wijnands M.V.W. Dietary fat and carcinogenesis. Mutat Res 443 (1999) 111-127
3. Ramesh A., Walker S.A., Hood D.B., Guillén M.D., Schneider K., and Weyand E.H. Bioavailability and risk assessment of orally ingested polycyclic aromatic hydrocarbons. Int J Toxicol 23 (2004) 301-333
4. IPCS. Environmental health criteria 202: selected non-heterocyclic polycyclic aromatic hydrocarbons (1998), World Health Organization, International Programme on Chemical Safety. Lyon (France)
5. Baars A.J., Theelen R.M.C., Janssen P.J.C.M., Hesse J.M., van Apeldoorn M.E., Meijerinck M.C.M., et al. Re-evaluation of human toxicological maximum permissible levels (2001), National Institute of Public Health and the Environment, Netherlands [RIVM report 711701025]
6. Wang J.S., and Busby Jr. W.F. Induction of lung and liver tumors by fluoranthene in a preweanling CD-1 mouse bioassay. Carcinogenesis 14 (1993) 1871-1874
7. Yamaguchi K., Near R., Shneider A., Cui H., Ju S.-T., and Sherr D.H. Fluoranthene-induced apoptosis in murine T cell hybridomas is independent of the aromatic hydrocarbon receptor. Toxicol Appl Pharmacol 139 (1996) 144-152
8. Knuckles M., Inyang F., and Ramesh A. Acute and subchronic oral toxicity of fluoranthene in F-344 rats. Ecotoxicol Environ Saf 59 (2004) 102-108
9. Gorelick N.J., Hutchins D.A., Tannenbaum S.R., and Wogan G.N. Formation of DNA and hemoglobin adducts of fluoranthene after single and multiple exposures. Carcinogenesis 10 (1989) 1579-1587
10. Xue W., and Warshawsky D. Metabolic activation of polycyclic and heterocyclic aromatic hydrocarbons and DNA damage: a review. Toxicol Appl Pharmacol 206 (2005) 73-93
11. NIH. Guidelines for the laboratory use of chemical carcinogens. NIH Publication No. 81-2385 (1981), National Institutes of Health US, Government Printing Office, Washington (DC)
12. Haught D., Koepke M., Goldberg-Heavilin L., Griffin A., and Cunha T. The essentials of custom diets for laboratory animals (2003), Purina Mills LLC, Richmond, Indiana 8
13. Holland B., Welch A.A., Unwin I.D., Buss D.H., Paul A.A., and Southgate D.A.T. McCance and Widdowson's the composition of foods (1992), The Royal Society of Chemistry, Cambridge (England) 462
14. Hu J., Zhang G., and Liu C.-Q. Pilot study of polycyclic aromatic hydrocarbons in surface soils of Guiyang city, People's Republic of China. Bull Environ Contam Toxicol 76 (2006) 80-89
15. NHANES. Daily dietary fat and total food-energy intakes: Third National Health and Nutrition Examination Survey, Phase I, 1988-1991. Morbidity and Mortality Weekly Report. 1994;43:116-7, 123-5.
16. USDA. Agriculture fact book 2001-2002 (2003), United States Department of Agriculture, Washington (DC) 310
17. 32P-postlabeling analysis of aromatic carcinogen: DNA adducts. Cancer Res 45 (1985) 5656-5662
18. 32P labeling and thin layer chromatography. In: Friedberg E.C., and Hanawalt P.C. (Eds). DNA Repair vol 3 (1988), Marcel Dekker, Inc, New York 399-418
19. Roth W.L., Freeman R.A., and Wilson G.E. A physiologically based model for gastrointestinal absorption and excretion of chemicals carried by lipids. Risk Anal 13 (1993) 531-543
20. Kararli T.T. Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals. Biopharm Drug Dispos 16 (1995) 351-380
21. Porter C.J., and Charman W.N. Intestinal lymphatic drug transport: an update. Adv Drug Deliv Rev 50 (2001) 61-80
22. Shen H., Howles P., and Tso P. From interaction of lipidic vehicles with intestinal epithelial cell membranes to the formation and secretion of chylomicrons. Adv Drug Deliv Rev 50 Suppl 1 (2001) S103-S125
23. Gershkovich P., and Hoffman A. Uptake of lipophilic drugs by plasma derived isolated chylomicrons: linear correlation with intestinal lymphatic bioavailability. Eur J Pharm Sci 26 (2005) 394-404
24. Vetter R.D., Carey M.C., and Patton J.S. Coassimilation of dietary fat and benzo(a)pyrene in the small intestine: an absorption model using the killifish. J Lipid Res 26 (1985) 428-434
25. Wasan K.M., and Cassidy S.M. Role of plasma lipoproteins in modifying the biological activity of hydrophobic drugs. J Pharm Sci 87 (1998) 411-424
26. Librando V., Sarpietro M.G., and Castelli F. Role of lipophilic medium in the absorption of polycyclic aromatic compounds by biomembranes. Environ Toxicol Pharmacol 14 (2003) 25-32
27. Lipniak M., and Brandys J. Toxicokinetics of fluoranthene, pyrene and benz(a)anthracene in the rat. Polycycl Aromat Compd 3 (1993) 111-119
28. Babson J.R., Russo-Rodriguez S., Wattley R.V., Bergstein P.L., Rastetter W.H., Liber H.L., et al. Microsomal activation of fluoranthene to mutagenic metabolites. Toxicol Appl Pharmacol 85 (1986) 355-366
29. Gower J.D., and Willis E.D. The dependence of the rate of benzo(a)pyrene metabolism in the rat small intestinal mucosa on the composition of the dietary fat. Nutr Cancer 8 (1986) 151-161
30. Gower J.D., Sayer J.W., and Willis E.D. The effect of dietary lipids and antioxidants on the activity of epoxide hydratase in the rat liver and intestine. Biochem Pharmacol 12 (1986) 1965-1969
31. Newman J.W., Morisseau C., and Hammock B.D. Epoxide hydrolases: their roles and interactions with lipid metabolism. Prog Lipid Res 44 (2005) 1-51
32. Stott W.T., Kan H.L., McFadden L.G., Sparrow B.R., and Gollapudi B.B. Effect of strain and diet upon constitutive and chemically induced activities of several xenobiotic-metabolizing enzymes in rats. Regul Toxicol Pharmacol 39 (2004) 325-333
33. Laher J.M., Rigler M.W., Vetter R.D., Barrowman J.A., and Patton J.S. Similar bioavailability and lymphatic transport of benzo(a)pyrene when administered to rats in different amounts of dietary fat. J Lipid Res 25 (1984) 1337-1342
34. Rahman A., Barrowman J.A., and Rahimtula A. The influence of bile on the bioavailability of polynuclear aromatic hydrocarbons from the rat intestine. Can J Physiol Pharmacol 64 (1986) 1214-1218
35. Kelly B.C., Gobas F.A.P.C., and McLachlan S. Intestinal absorption and biomagnification of organic contaminants in fish, wildlife, and humans. Environ Toxicol Chem 23 (2004) 2324-2336
36. Wall K.L., Gao W., te Koppele J.M., Kwei G.Y., Kauffman F.C., and Thurman R.G. The liver plays a central role in the mechanism of chemical carcinogenesis due to polycyclic aromatic hydrocarbons. Carcinogenesis 12 (1991) 783-786
37. Doherty M.M., and Charman W.N. The mucosa of the small intestine-how clinically relevant as an organ of drug metabolism?. Clin Pharmacokinet 41 (2002) 235-253
38. Choi S.H., Nishikawa M., Sakoda A., and Sakai Y. Feasibility of a simple double-layered coculture system incorporating metabolic processes of the intestine and liver tissue: application to the analysis of benzo(a)pyrene toxicity. Toxicol In Vitro 18 (2004) 393-402
39. Cavret S., Rychen G., and Feidt C. In vitro intestinal transfer and metabolism of polycyclic aromatic hydrocarbons. Polycycl Aromat Compd 24 (2004) 513-525
40. 2-deoxyguanosine adduct. Carcinogenesis 7 (1986) 859-865
41. Rice J.E., Bedenko V., Lavoie E.J., and Hoffman D. Studies on the metabolism of fluoranthene and 3-methylfluoranthene. In: Cooke M., and Denouś A.J. (Eds). Polynuclear aromatic hydrocarbons: formation, metabolism and measurement (1983), Battelle Press, Richland 1009-1020
42. Polcaro C., Nicoletti I., Ossicini L., Caponecchi G., Cozzi R., Fiore M., et al. Chromatographic and cytogenetic analysis of in vivo metabolites of fluoranthene. J Chromatogr 448 (1988) 127-133
43. Walker S.A., Whitten L.B., Seals G.B., Lee W.E., Archibong A.E., and Ramesh A. Inter-species comparison of liver and small intestinal microsomal metabolism of fluoranthene. Food Chem Toxicol 44 (2006) 380-387
44. Day B.W., Sahali Y., Hutchins D.A., Wildschütte M., Pastorelli R., Nguyen T.T., et al. Fluoranthene metabolism: human and rat liver microsomes display different stereoselective formation of the trans-2, 3-dihydrodiol. Chem Res Toxicol 5 (1992) 779-786
45. Busbee D.L., Norman J.O., and Ziprin R.L. Comparative uptake, vascular transport, and cellular internalization of aflatoxin B1 and benzo(a)-pyrene. Arch Toxicol 64 (1990) 285-290
46. Willis E.D. Effects of dietary lipids on the metabolism of polycyclic hydrocarbons and the binding of their metabolites to DNA. Biochem Soc Trans 11 (1983) 258-261
47. Gower J.D. The oxidation of benzo(a)pyrene 7, 8-dihydrodiol mediated by lipid peroxidation in the rat intestine and the effect of dietary lipids. Chem Biol Interact 63 (1987) 63-74
48. Schaffer E.M., and Milner J.A. Impact of dietary fatty acids on 7, 12-dimethylbenz[a]anthracene-induced mammary DNA adducts. Cancer Lett 106 (1996) 177-183
49. Curfs D.M.J., Beckers L., Godschalk R.W.L., Gijbels M.J.J., and van Schooten F.J. Modulation of plasma lipid levels affects benzo(a)pyrene-induced DNA damage in tissues of two hyperlipidemic mouse models. Environ Mol Mutagen 42 (2003) 243-249
50. Stavenow L., and Pessah-Rasmussen H. Effects of polycyclic aromatic hydrocarbons on proliferation, collagen secretion and viability of arterial smooth muscle cells in culture. Artery 2 (1988) 94-108
51. Martinet W., Knaapen M.W., De Meyer G.R., Herman A.G., and Kockx M.M. Oxidative DNA damage and repair in experimental atherosclerosis are reversed by dietary lipid lowering. Circ Res 7 (2001) 733-739
52. Culp S.J., Gaylor D.W., Sheldon W.G., Goldstein L.S., and Beland F.A. A comparison of the tumors induced by coal tar and benzo(a)pyrene in a 2-year bioassay. Carcinogenesis 19 (1998) 117-124