In utero exposure to benzo(a)pyrene predisposes offspring to cardiovascular dysfunction in later-life

Toxicology

Volumn 295, Issue 1-3, 2012, Pages 56-67

  Jules, G E ^a   Pratap, S ^a   Ramesh, A ^a   Hood, D B ^a  

^a MEHARRY MEDICAL COLLEGE   (United States)

Author keywords

Angiotensin; Benzo(a)pyrene; Cardiovascular diseases; Hypertension; Microarray; Susceptibility exposure paradigm

Indexed keywords

ANGIOTENSIN II; ANGIOTENSINOGEN; BENZO[A]PYRENE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MESSENGER RNA; TRANSCRIPTOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DISEASE PREDISPOSITION; EMBRYO DEVELOPMENT; GENETIC ANALYSIS; GROWTH RATE; HYPERTENSION; MICROARRAY ANALYSIS; NONHUMAN; PERINATAL PERIOD; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; SYSTOLIC BLOOD PRESSURE; UPREGULATION; ANIMAL; BODY WEIGHT; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; DRUG EFFECT; FEMALE; FETUS; GENETICS; LONG EVANS RAT; MOUSE; PREGNANCY; SYSTOLE;

ANIMALIA; RATTUS;

ANIMALS; BENZO(A)PYRENE; BODY WEIGHT; CARDIOVASCULAR DISEASES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FETUS; MICE; NITRIC OXIDE SYNTHASE TYPE III; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, LONG-EVANS; RNA, MESSENGER; SYSTOLE; TRANSCRIPTOME;

EID: 84861131340     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2012.01.017     Document Type: Article

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