Critical role of ASC inflammasomes and bacterial type IV secretion system in caspase-1 activation and host innate resistance to Brucella abortus infection

Journal of Immunology

Volumn 190, Issue 7, 2013, Pages 3629-3638

  Gomes, Marco Tulio R ^a   Campos, Priscila C ^a   Oliveira, Fernanda S ^a   Corsetti, Patricia P ^a   Bortoluci, Karina R ^b   Cunha, Larissa D ^c   Zamboni, Dario S ^c   Oliveira, Sergio C ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LACTATE DEHYDROGENASE; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; PROTEIN AIM2; PROTEIN NLRC4; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; BRUCELLA; BRUCELLOSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; GENETIC TRANSFECTION; HISTOPATHOLOGY; HOST RESISTANCE; IN VITRO STUDY; INFECTION SENSITIVITY; KNOCKOUT MOUSE; LIVER; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN; TYPE IV SECRETION SYSTEM; WESTERN BLOTTING; WILD TYPE;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; BACTERIAL SECRETION SYSTEMS; BRUCELLA ABORTUS; BRUCELLOSIS; CALCIUM-BINDING PROTEINS; CARRIER PROTEINS; CASPASE 1; CYTOSKELETAL PROTEINS; DNA, BACTERIAL; ENZYME ACTIVATION; GENETIC PREDISPOSITION TO DISEASE; GRANULOMA; IMMUNITY, INNATE; INFLAMMASOMES; INTERLEUKIN-18; INTERLEUKIN-1BETA; LIVER; MACROPHAGES; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MYELOID DIFFERENTIATION FACTOR 88; NUCLEAR PROTEINS; REACTIVE OXYGEN SPECIES; RECEPTORS, INTERLEUKIN-1;

EID: 84875431649     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1202817     Document Type: Article

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