A novel pathway for inducible nitric-oxide synthase activation through inflammasomes

Journal of Biological Chemistry

Volumn 285, Issue 42, 2010, Pages 32087-32095

  Buzzo, Carina L ^a   Campopiano, Julia C ^a   Massis, Liliana M ^a   Lage, Silvia L ^a   Cassado, Alexandra A ^a   Leme Souza, Rafael ^a   Cunha, Larissa D ^a   Russo, Momtchilo ^a   Zamboni, Dario S ^a   Amarante Mendes, Gustavo P ^a,b   Bortoluci, Karina R ^a,c  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b Instituto Nacional de Ciencia e Tecnologia   (Brazil)

^c FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE ACTIVATION; CASPASES; CYTOSOLIC; EXTRACELLULAR; IMMUNE RECOGNITION; INFLAMMATORY GENES; INHIBITORY PROTEINS; MULTI-PROTEIN COMPLEX; NEURONAL APOPTOSIS; NITRIC-OXIDE SYNTHASE; SIGNALING TRANSDUCTION; TRANSMEMBRANES;

CELL DEATH;

ENZYME ACTIVITY;

FLAGELLIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MYELOID DIFFERENTIATION FACTOR 88; NEURONAL APOPTOSIS INHIBITORY PROTEIN; NEURONAL APOPTOSIS INHIBITORY PROTEIN 5; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; TOLL LIKE RECEPTOR 5; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME SYNTHESIS; FEMALE; HOST RESISTANCE; MACROPHAGE ACTIVATION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CALCIUM-BINDING PROTEINS; ENZYME ACTIVATION; FEMALE; FLAGELLIN; IMMUNITY, INNATE; INFLAMMATION; INTERLEUKIN-18; INTERLEUKIN-1BETA; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MULTIPROTEIN COMPLEXES; MYELOID DIFFERENTIATION FACTOR 88; NEURONAL APOPTOSIS-INHIBITORY PROTEIN; NITRIC OXIDE SYNTHASE TYPE II; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 5;

EID: 77957766952     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.124297     Document Type: Article

References (47)

1. Franchi, L., Eigenbrod, T., Muñoz-Planillo, R., and Nuñez, G. (2009) Nat. Immunol. 10, 241-247
2. Medzhitov, R. (2007) Nature 449, 819-826
3. Akira, S., and Takeda, K. (2004) Nat. Rev. Immunol. 4, 499-511
4. Iwasaki, A., and Medzhitov, R. (2004) Nat. Immunol. 5, 987-995
5. Inohara, N., Ogura, Y., Fontalba, A., Gutierrez, O., Pons, F., Crespo, J., Fukase, K., Inamura, S., Kusumoto, S., Hashimoto, M., Foster, S. J., Moran, A. P., Fernandez-Luna, J. L., and Nuñez, G., (2003) J. Biol. Chem. 278, 5509-5512
6. Inohara, Chamaillard, McDonald, C., and Nuñez, G. (2005) Annu. Rev. Biochem. 74, 355-383
7. Bortoluci, K. R., and Medzhitov, R. (2010) Cell. Mol. Life Sci. 67, 1643-1651
8. Hayashi, F., Smith, K. D., Ozinsky, A., Hawn, T. R., Yi, E. C., Goodlett, D. R., Eng, J. K., Akira, S., Underhill, D. M., and Aderem, A. (2001) Nature 410, 1099-1103
9. Amer, A., Franchi, L., Kanneganti, T. D., Body-Malapel, M., Ozören, N., Brady, G., Meshinchi, S., Jagirdar, R., Gewirtz, A., Akira, S., and Núñez, G. (2006) J. Biol. Chem. 281, 35217-35223
10. Franchi, L., Amer, A., Body-Malapel, M., Kanneganti, T. D., Ozören, N., Jagirdar, R., Inohara, N., Vandenabeele, P., Bertin, J., Coyle, A., Grant, E. P., and Núñez, G. (2006) Nat. Immunol. 7, 576-582
11. Lightfield, K. L., Persson, J., Brubaker, S. W., Witte, C. E., von Moltke, J., Dunipace, E. A., Henry, T., Sun, Y. H., Cado, D., Dietrich, W. F., Monack, D. M., Tsolis, R. M., and Vance, R. E. (2008) Nat. Immunol. 9, 1171-1178
12. Mariathasan, S., Newton, K., Monack, D. M., Vucic, D., French, D. M., Lee, W. P., Roose-Girma, M., Erickson, S., and Dixit, V. M. (2004) Nature 430, 213-218
13. Zamboni, D. S., Kobayashi, K. S., Kohlsdorf, T., Ogura, Y., Long, E. M., Vance, R. E., Kuida, K., Mariathasan, S., Dixit, V. M., Flavell, R. A., Dietrich, W. F., and Roy, C. R. (2006) Nat. Immunol. 7, 318-325
14. Brightbill, H. D., Libraty, D. H., Krutzik, S. R., Yang, R. B., Belisle, J. T., Bleharski, J. R., Maitland, M., Norgard, M. V., Plevy, S. E., Smale, S. T., Brennan, P. J., Bloom, B. R., Godowski, P. J., and Modlin, R. L. (1999) Science 285, 732-736
15. Thoma-Uszynski, S., Stenger, S., Takeuchi, O., Ochoa, M. T., Engele, M., Sieling, P. A., Barnes, P. F., Rollinghoff, M., Bolcskei, P. L., Wagner, M., Akira, S., Norgard, M. V., Belisle, J. T., Godowski, P. J., Bloom, B. R., and Modlin, R. L. (2001) Science 291, 1544-1547
16. Bogdan, C. (2001) Trends Cell Biol. 11, 66-75
17. Lara-Tejero, M., Sutterwala, F. S., Ogura, Y., Grant, E. P., Bertin, J., Coyle, A. J., Flavell, R. A., and Galán, J. E. (2006) J. Exp. Med. 203, 1407-1412
18. Wright, E. K., Goodart, S. A., Growney, J. D., Hadinoto, V., Endrizzi, M. G., Long, E. M., Sadigh, K., Abney, A. L., Bernstein-Hanley, I., and Dietrich, W. F.. (2003) Curr. Biol. 13, 27-36
19. Zamboni, D. S., and Rabinovitch, M. (2003) Infect. Immun. 71, 1225-1233
20. Bastos, K. R., Alvarez, J. M., Marinho, C. R., Rizzo, L. V., and Lima, M. R. (2002) J. Leukoc. Biol. 71, 271-278
21. Simberg, D., Weisman, S., Talmon, Y., and Barenholz, Y. (2004) Crit. Rev. Ther. Drug Carrier Syst. 21, 257-317
22. Weinlich, R., Bortoluci, K. R., Chehab, C. F., Serezani, C. H., Ulbrich, A. G., Peters-Golden, M., Russo, M., and Amarante-Mendes, G. P. (2008) Cell Death Differ. 15, 1901-1909
23. Misko, T. P., Moore, W. M., Kasten, T. P., Nickols, G. A., Corbett, J. A., Tilton, R. G., McDaniel, M. L., Williamson, J. R., and Currie, M. G. (1993) Eur. J. Pharmacol. 233, 119-125
24. Diez, E., Lee, S. H., Gauthier, S., Yaraghi, Z., Tremblay, M., Vidal, S., and Gros, P. (2003) Nat. Genet. 33, 55-60
25. Dinarello, C. A. (2009) Annu. Rev. Immunol. 27, 519-550
26. Ren, T., Zamboni, D. S., Roy, C. R., Dietrich, W. F., and Vance, R. E. (2006) PLoS Pathog. 2, e18
27. Miao, E. A., Alpuche-Aranda, C. M., Dors, M., Clark, A. E., Bader, M. W., Miller, S. I., and Aderem, A. (2006) Nat. Immunol. 7, 569-575
28. Silveira, T. N., and Zamboni, D. S. (2010) Infect. Immun. 78, 1403-1413
29. Bogdan, C. (2001) Nat. Immunol. 2, 907-916
30. Kamijo, R., Harada, H., Matsuyama, T., Bosland, M., Gerecitano, J., Shapiro, D., Le, J., Koh, S. I., Kimura, T., and Green, S. J. (1994) Science 263, 1612-1615
31. Lowenstein, C. J., Alley, E. W., Raval, P., Snowman, A. M., Snyder, S. H., Russell, S. W., and Murphy, W. J. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 9730-9734
32. Tattoli, I., Travassos, L. H., Carneiro, L. A., Magalhaes, J. G., and Girardin, S. E. (2007) Semin. Immunopathol. 29, 289-301
33. Tötemeyer, S., Sheppard, M., Lloyd, A., Roper, D., Dowson, C., Underhill, D., Murray, P., Maskell, D., and Bryant, C. (2006) J. Immunol. 176, 4804-4810
34. Ting, J. P., Willingham, S. B., and Bergstralh, D. T. (2008) Nat. Rev. Immunol. 8, 372-379
35. Miao, E. A., Ernst, R. K., Dors, M., Mao, D. P., and Aderem, A. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 2562-2567
36. Sutterwala, F. S., Mijares, L. A., Li, L., Ogura, Y., Kazmierczak, B. I., and Flavell, R. A. (2007) J. Exp. Med. 204, 3235-3245
37. Suzuki, T., Franchi, L., Toma, C., Ashida, H., Ogawa, M., Yoshikawa, Y., Mimuro, H., Inohara, N., Sasakawa, C., and Nuñez, G. (2007) PLoS Pathog. 3, e111
38. Jüttler, E., Bonmann, E., Spranger, M., Kolb-Bachofen, V., and Suschek, C. V. (2007) Mol. Cell. Neurosci. 34, 612-620
39. Fortier, A., Doiron, K., Saleh, M., Grinstein, S., and Gros, P. (2009) Infect. Immun. 77, 4794-4805
40. Poyet, J. L., Srinivasula, S. M., Tnani, M., Razmara, M., Fernandes-Alnemri, T., and Alnemri, E. S. (2001) J. Biol. Chem. 276, 28309-28313
41. Martinon, F., and Tschopp, J. (2007) Cell Death Differ. 14, 10-22
42. Mace, P. D., Shirley, S., and Day, C. L. (2010) Cell Death Differ. 17, 46-53
43. Bergsbaken, T., Fink, S. L., and Cookson, B. T. (2009) Nature Reviews 7, 99-109
44. Akhter, A., Gavrilin, M. A., Frantz, L., Washington, S., Ditty, C., Limoli, D., Day, C., Sarkar, A., Newland, C., Butchar, J., Marsh, C. B., Wewers, M. D., Tridandapani, S., Kanneganti, T. D., and Amer, A. O. (2009) PLoS Pathog. 5, e1000361
45. Summersgill, J. T., Powell, L. A., Buster, B. L., Miller, R. D., and Ramirez, J. A. (1992) J. Leukoc. Biol. 52, 625-629
46. Skerrett, S. J., and Martin, T. R. (1996) Infect. Immun. 64, 3236-3243
47. Gebran, S. J., Yamamoto, Y., Newton, C., Klein, T. W., and Friedman, H. (1994) Infect. Immun. 62, 3197-3205