메뉴 건너뛰기




Volumn 64, Issue 6, 1996, Pages 1961-1967

Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12;

EID: 0030010929     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.6.1961-1967.1996     Document Type: Article
Times cited : (236)

References (34)
  • 1
    • 0029099391 scopus 로고
    • IL-12 effects on immune responses to microbial infections in regulating disease outcome
    • Biron, C. A., and R. T. Gazzinelli. 1995. IL-12 effects on immune responses to microbial infections in regulating disease outcome. Curr. Opin. Immunol. 7:485-496.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 485-496
    • Biron, C.A.1    Gazzinelli, R.T.2
  • 2
    • 0030025945 scopus 로고    scopus 로고
    • Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin-10: The role of NK cells
    • Cardillo, F., J. C. Voltarelli, S. G. Reed, and J. S. Silva. 1996. Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin-10: the role of NK cells. Infect. Immun. 64:128-134.
    • (1996) Infect. Immun. , vol.64 , pp. 128-134
    • Cardillo, F.1    Voltarelli, J.C.2    Reed, S.G.3    Silva, J.S.4
  • 5
    • 0026805989 scopus 로고
    • The microbicidal activity of interferon-γ-treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-β
    • Gazzinelli, R. T., I. P. Oswald, S. Hieny, L. James, and A. Sher. 1992. The microbicidal activity of interferon-γ-treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-β. Eur. J. Immunol. 22:2501-2506.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2501-2506
    • Gazzinelli, R.T.1    Oswald, I.P.2    Hieny, S.3    James, L.4    Sher, A.5
  • 6
    • 0027939611 scopus 로고
    • Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii
    • Gazzinelli, R. T., M. Wysocka, S. Hayashi, E. Y. Denkers, S. Hieny, P. Caspar, G. Trinchieri, and A. Sher. 1994. Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii. J. Immunol. 153:2533-2543.
    • (1994) J. Immunol. , vol.153 , pp. 2533-2543
    • Gazzinelli, R.T.1    Wysocka, M.2    Hayashi, S.3    Denkers, E.Y.4    Hieny, S.5    Caspar, P.6    Trinchieri, G.7    Sher, A.8
  • 7
    • 9344261016 scopus 로고
    • Reticulo-endothelial blockade in experimental Chagas' disease
    • Goble, F. C., and J. L. Boyd. 1962. Reticulo-endothelial blockade in experimental Chagas' disease. J. Parasitol. 48:223-230.
    • (1962) J. Parasitol. , vol.48 , pp. 223-230
    • Goble, F.C.1    Boyd, J.L.2
  • 8
    • 0028987734 scopus 로고
    • Transforming growth factor-β inhibits interleukin-12 induced production of interferon by natural killer cells: A role for transforming growth factor-β in the regulation of the T cell independent resistance to Toxoplasma gondii
    • Hunter, C. A., L. Bermudez, H. Beernick, W. Waegell, and J. Remington. 1995. Transforming growth factor-β inhibits interleukin-12 induced production of interferon by natural killer cells: a role for transforming growth factor-β in the regulation of the T cell independent resistance to Toxoplasma gondii. Eur. J. Immunol. 25:994-1000.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 994-1000
    • Hunter, C.A.1    Bermudez, L.2    Beernick, H.3    Waegell, W.4    Remington, J.5
  • 9
    • 0020060405 scopus 로고
    • Enhanced resistance to acute infection with Trypanosoma cruzi in mice treated with an interferon inducer
    • James, S. L., T. L. Kipnis, A. Sher, and R. Hoff. 1982. Enhanced resistance to acute infection with Trypanosoma cruzi in mice treated with an interferon inducer. Infect. Immun. 35:588-593.
    • (1982) Infect. Immun. , vol.35 , pp. 588-593
    • James, S.L.1    Kipnis, T.L.2    Sher, A.3    Hoff, R.4
  • 10
    • 0024467154 scopus 로고
    • Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
    • Kobayashi, M., L. Fitz, M. Ryan, R. M. Hewick, S. C. Clark, S. Chan, R. Loudon, A. Sherman, B. Perussia, and G. Trinchieri. 1989. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J. Exp. Med. 170:827-845.
    • (1989) J. Exp. Med. , vol.170 , pp. 827-845
    • Kobayashi, M.1    Fitz, L.2    Ryan, M.3    Hewick, R.M.4    Clark, S.C.5    Chan, S.6    Loudon, R.7    Sherman, A.8    Perussia, B.9    Trinchieri, G.10
  • 11
    • 0017225232 scopus 로고
    • Protective effects of specific antibodies in Trypanosoma cruzi infections
    • Krettli, A. U., and Z. Brener. 1976. Protective effects of specific antibodies in Trypanosoma cruzi infections. J. Immunol. 116:755-760.
    • (1976) J. Immunol. , vol.116 , pp. 755-760
    • Krettli, A.U.1    Brener, Z.2
  • 13
    • 0018184199 scopus 로고
    • Tissue tropism of different Trypanosoma cruzi strains
    • Melo, R. C., and Z. Brener. 1978. Tissue tropism of different Trypanosoma cruzi strains. J. Parasitol. 64:475-482.
    • (1978) J. Parasitol. , vol.64 , pp. 475-482
    • Melo, R.C.1    Brener, Z.2
  • 14
    • 0018357483 scopus 로고
    • Activation of macrophages in vivo and in vitro: Correlation between hydrogen peroxide release and killing of Trypanosoma cruzi
    • Nathan, C., N. Nogueira, C. Juangbhanich, J. Ellis, and Z. Conn. 1979. Activation of macrophages in vivo and in vitro: correlation between hydrogen peroxide release and killing of Trypanosoma cruzi. J. Exp. Med. 149: 1056-1068.
    • (1979) J. Exp. Med. , vol.149 , pp. 1056-1068
    • Nathan, C.1    Nogueira, N.2    Juangbhanich, C.3    Ellis, J.4    Conn, Z.5
  • 15
    • 0026034432 scopus 로고
    • Role of nitric oxide synthesis in macrophage antimicrobial activity
    • Nathan, C. F., and J. B. Hibbs, Jr. 1991. Role of nitric oxide synthesis in macrophage antimicrobial activity. Curr. Opin. Immunol. 3:65-70.
    • (1991) Curr. Opin. Immunol. , vol.3 , pp. 65-70
    • Nathan, C.F.1    Hibbs Jr., J.B.2
  • 16
    • 0018141760 scopus 로고
    • Trypanosoma cruzi: In vitro induction of macrophage microbial activity
    • Nogueira, N., and Z. Cohn. 1978. Trypanosoma cruzi: in vitro induction of macrophage microbial activity. J. Exp. Med. 148:288-300.
    • (1978) J. Exp. Med. , vol.148 , pp. 288-300
    • Nogueira, N.1    Cohn, Z.2
  • 17
    • 0028266819 scopus 로고
    • Effects of IL-12 on the response to experimental viral infections
    • Orange, J. S., S. F. Wolf, and C. A. Biron. 1994. Effects of IL-12 on the response to experimental viral infections. J. Immunol. 152:1253-1264.
    • (1994) J. Immunol. , vol.152 , pp. 1253-1264
    • Orange, J.S.1    Wolf, S.F.2    Biron, C.A.3
  • 18
    • 0023770735 scopus 로고
    • In viva administration of recombinant IFN-gamma induces macrophage activation, and prevents acute disease, immune suppression, and death in experimental Trypanosoma cruzi infection
    • Reed, S. G. 1988. In viva administration of recombinant IFN-gamma induces macrophage activation, and prevents acute disease, immune suppression, and death in experimental Trypanosoma cruzi infection. J. Immunol. 140: 4342-4347.
    • (1988) J. Immunol. , vol.140 , pp. 4342-4347
    • Reed, S.G.1
  • 20
    • 0024253490 scopus 로고
    • Resistance to Trypanosoma cruzi requires T helper inductor cells as well as natural killer cells
    • Rottenberg, M. E., R. Cardoni, R. Andersson, E. Segura, and A. Orn. 1988. Resistance to Trypanosoma cruzi requires T helper inductor cells as well as natural killer cells. Scand. J. Immunol. 30:573-582.
    • (1988) Scand. J. Immunol. , vol.30 , pp. 573-582
    • Rottenberg, M.E.1    Cardoni, R.2    Andersson, R.3    Segura, E.4    Orn, A.5
  • 21
    • 0023938675 scopus 로고
    • Parasitic load increases and myocardial inflammation decreases in Trypanosoma cruzi-infected mice after inactivation of helper T cells
    • Russo, M., N. Starobinas, P. Minoprio, A. Coutinho, and M. Hontebeyrie-Joskowicz. 1988. Parasitic load increases and myocardial inflammation decreases in Trypanosoma cruzi-infected mice after inactivation of helper T cells. Ann. Inst. Pasteur/Immunol. 139:225-236.
    • (1988) Ann. Inst. Pasteur/Immunol. , vol.139 , pp. 225-236
    • Russo, M.1    Starobinas, N.2    Minoprio, P.3    Coutinho, A.4    Hontebeyrie-Joskowicz, M.5
  • 22
    • 0027241272 scopus 로고
    • Toxoplasma gondii induces a T-independent IFN-γ response in natural killer cells that requires both adherent accessory cells and tumor necrosis factor-α
    • Sher, A., I. Oswald, S. Hieny, and R. T. Gazzinelli. 1993. Toxoplasma gondii induces a T-independent IFN-γ response in natural killer cells that requires both adherent accessory cells and tumor necrosis factor-α. J. Immunol. 150:3982-3989.
    • (1993) J. Immunol. , vol.150 , pp. 3982-3989
    • Sher, A.1    Oswald, I.2    Hieny, S.3    Gazzinelli, R.T.4
  • 24
    • 0025741792 scopus 로고
    • Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor-beta
    • Silva, J. S., D. Twardzik, and S. G. Reed. 1991. Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor-beta. J. Exp. Med. 174:539-545.
    • (1991) J. Exp. Med. , vol.174 , pp. 539-545
    • Silva, J.S.1    Twardzik, D.2    Reed, S.G.3
  • 25
    • 0028807425 scopus 로고
    • Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages
    • Silva, J. S., G. N. R. Vespa, M. A. Cardoso, J. C. S. Aliberti, and F. Q. Cunha. 1995. Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages. Infect. Immun. 63:4862-4867.
    • (1995) Infect. Immun. , vol.63 , pp. 4862-4867
    • Silva, J.S.1    Vespa, G.N.R.2    Cardoso, M.A.3    Aliberti, J.C.S.4    Cunha, F.Q.5
  • 27
    • 0026536194 scopus 로고
    • Susceptibility of beta 2-microglobulin-deficient mice to Trypanosoma cruzi infection
    • Tarleton, R., B. H. Koller, A. Latour, and M. Postan. 1992. Susceptibility of beta 2-microglobulin-deficient mice to Trypanosoma cruzi infection. Nature (London) 356:338-340.
    • (1992) Nature (London) , vol.356 , pp. 338-340
    • Tarleton, R.1    Koller, B.H.2    Latour, A.3    Postan, M.4
  • 28
    • 0025117462 scopus 로고
    • Depletion of CD8 T cells increases susceptibility and reverses vaccine-induced immunity in mice infected with Trypanosoma cruzi
    • Tarleton, R. L. 1990. Depletion of CD8 T cells increases susceptibility and reverses vaccine-induced immunity in mice infected with Trypanosoma cruzi. J. Immunol. 144:717-724.
    • (1990) J. Immunol. , vol.144 , pp. 717-724
    • Tarleton, R.L.1
  • 29
    • 0025829971 scopus 로고
    • Endogenous IFN-γ is required for resistance to acute Trypanosoma cruzi infection in mice
    • Torrico, F., H. Heremans, M. T. Rivera, E. V. Marck, A. Billiau, and Y. Carlier. 1991. Endogenous IFN-γ is required for resistance to acute Trypanosoma cruzi infection in mice. J. Immunol. 146:3626-3632.
    • (1991) J. Immunol. , vol.146 , pp. 3626-3632
    • Torrico, F.1    Heremans, H.2    Rivera, M.T.3    Marck, E.V.4    Billiau, A.5    Carlier, Y.6
  • 30
    • 0028209541 scopus 로고
    • Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-gamma
    • Tripp, C. S., M. K. Gately, J. Hakimi, P. Ling, and E. R. Unanue. 1994. Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-gamma. J. Immunol. 152:1883-1887.
    • (1994) J. Immunol. , vol.152 , pp. 1883-1887
    • Tripp, C.S.1    Gately, M.K.2    Hakimi, J.3    Ling, P.4    Unanue, E.R.5
  • 31
    • 0027530129 scopus 로고
    • Interleukin 12 and tumor necrosis factor α are costimulators of interferon γ production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist
    • Tripp, C. S., S. F. Wolf, and E. R. Unanue. 1993. Interleukin 12 and tumor necrosis factor α are costimulators of interferon γ production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist. Proc. Natl. Acad. Sci. USA 90: 3725-3729.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3725-3729
    • Tripp, C.S.1    Wolf, S.F.2    Unanue, E.R.3
  • 32
    • 0023726231 scopus 로고
    • Deactivation of macrophages by transforming growth factor-β
    • Tsunawaki, S., M. Spron, A. Ding, and C. F. Nathan. 1988. Deactivation of macrophages by transforming growth factor-β. Nature (London) 334:260-262.
    • (1988) Nature (London) , vol.334 , pp. 260-262
    • Tsunawaki, S.1    Spron, M.2    Ding, A.3    Nathan, C.F.4
  • 33
    • 0028051548 scopus 로고
    • Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro
    • Vespa, G. N. R., F. Q. Cunha, and J. S. Silva. 1994. Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro. Infect. Immun. 62:5177-5182.
    • (1994) Infect. Immun. , vol.62 , pp. 5177-5182
    • Vespa, G.N.R.1    Cunha, F.Q.2    Silva, J.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.