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Volumn 66, Issue 3, 1998, Pages 1208-1215

Defective nitric oxide effector functions lead to extreme susceptibility of Trypanosoma cruzi-infected mice deficient in gamma interferon receptor or inducible nitric oxide synthase

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON RECEPTOR; NITRIC OXIDE SYNTHASE;

EID: 0031913243     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.3.1208-1215.1998     Document Type: Article
Times cited : (222)

References (49)
  • 1
    • 0030298134 scopus 로고    scopus 로고
    • Trypanosoma cruzi-IL-10, TNF, IFN-gamma, and IL-12 regulate innate and acquired-immunity to infection
    • Abrahamsohn, I. A., and R. L. Coffman. 1996. Trypanosoma cruzi-IL-10, TNF, IFN-gamma, and IL-12 regulate innate and acquired-immunity to infection. Exp. Parasital. 84:231-244.
    • (1996) Exp. Parasital. , vol.84 , pp. 231-244
    • Abrahamsohn, I.A.1    Coffman, R.L.2
  • 2
    • 0030010929 scopus 로고    scopus 로고
    • Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes
    • Aliberti, J. C., M. A. Cardoso, G. A. Martins, R. T. Gazzinelli, L. Q. Vieira, and J. S. Silva. 1996. Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes. Infect. Immun. 64:1961-1967.
    • (1996) Infect. Immun. , vol.64 , pp. 1961-1967
    • Aliberti, J.C.1    Cardoso, M.A.2    Martins, G.A.3    Gazzinelli, R.T.4    Vieira, L.Q.5    Silva, J.S.6
  • 3
    • 0028100281 scopus 로고
    • Nitrite production by macrophages derived from BCG-resistant and -susceptible congenic mouse strains in response to IFN-gamma and infection with BCG
    • Barrera, L. F., I. Kramnik, E. Skamene, and D. Radzioch. 1994. Nitrite production by macrophages derived from BCG-resistant and -susceptible congenic mouse strains in response to IFN-gamma and infection with BCG. Immunology 82:457-464.
    • (1994) Immunology , vol.82 , pp. 457-464
    • Barrera, L.F.1    Kramnik, I.2    Skamene, E.3    Radzioch, D.4
  • 4
    • 0025854274 scopus 로고
    • The double-edged role of nitric oxide in brain function and superoxide-mediated injury
    • Beckman, J. S. 1991. The double-edged role of nitric oxide in brain function and superoxide-mediated injury. J. Dev. Physiol. 15:53-59.
    • (1991) J. Dev. Physiol. , vol.15 , pp. 53-59
    • Beckman, J.S.1
  • 5
    • 0029099391 scopus 로고
    • Effects of IL-12 on immune responses to microbial infections: A key mediator in regulating disease outcome
    • Biron, C. A., and R. T. Gazzinelli. 1995. Effects of IL-12 on immune responses to microbial infections: a key mediator in regulating disease outcome. Curr. Opin. Immunol. 7:485-496.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 485-496
    • Biron, C.A.1    Gazzinelli, R.T.2
  • 6
    • 0030425980 scopus 로고    scopus 로고
    • Innate versus acquired immunity in listeriosis
    • Brombacher, F., and M. Kopf. 1996. Innate versus acquired immunity in listeriosis. Res. Immunol. 147:505-511.
    • (1996) Res. Immunol. , vol.147 , pp. 505-511
    • Brombacher, F.1    Kopf, M.2
  • 7
    • 0027490938 scopus 로고
    • An age-related gamma delta T cell suppressor activity correlates with the outcome of autoimmunity in experimental Trypanosoma cruzi infection
    • Cardillo, F., R. P. Falcao, M. A. Rossi, and J. Mengel. 1993. An age-related gamma delta T cell suppressor activity correlates with the outcome of autoimmunity in experimental Trypanosoma cruzi infection. Eur. J. Immunol. 23:2597-2605.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 2597-2605
    • Cardillo, F.1    Falcao, R.P.2    Rossi, M.A.3    Mengel, J.4
  • 8
    • 0030025945 scopus 로고    scopus 로고
    • Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin 10: Role of NK cells
    • Cardillo, F., J. C. Voltarelli, S. G. Reed, and J. S. Silva. 1996. Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin 10: role of NK cells. Infect. Immun. 64:128-134.
    • (1996) Infect. Immun. , vol.64 , pp. 128-134
    • Cardillo, F.1    Voltarelli, J.C.2    Reed, S.G.3    Silva, J.S.4
  • 9
    • 0018884533 scopus 로고
    • Trypanosoma cruzi-induced suppression of the primary immune response in murine cell cultures to T-cell-dependent and -independent antigens
    • Cunningham, D. S., and R. E. Kuhn. 1980. Trypanosoma cruzi-induced suppression of the primary immune response in murine cell cultures to T-cell-dependent and -independent antigens. J. Parasitol. 66:16-27.
    • (1980) J. Parasitol. , vol.66 , pp. 16-27
    • Cunningham, D.S.1    Kuhn, R.E.2
  • 10
    • 0025305239 scopus 로고
    • Trypanosoma cruzi: Maintenance of parasite-specific T cell responses in lymph nodes during the acute phase of the infection
    • Curotto de Lafaille, M. A., L. C. Barbosa de Oliveira, G. C. Lima, and I. A. Abrahamsohn. 1990. Trypanosoma cruzi: maintenance of parasite-specific T cell responses in lymph nodes during the acute phase of the infection. Exp. Parasitol. 70:164-174.
    • (1990) Exp. Parasitol. , vol.70 , pp. 164-174
    • Curotto De Lafaille, M.A.1    Barbosa De Oliveira, L.C.2    Lima, G.C.3    Abrahamsohn, I.A.4
  • 11
    • 0031091727 scopus 로고    scopus 로고
    • Both innate and acquired immunity to Listeria monocytogenes infection are increased in IL-10 deficient mice
    • Dai, W. D., G. Köhler, and F. Brombacher. 1997. Both innate and acquired immunity to Listeria monocytogenes infection are increased in IL-10 deficient mice. J. Immunol. 158:2259-2267.
    • (1997) J. Immunol. , vol.158 , pp. 2259-2267
    • Dai, W.D.1    Köhler, G.2    Brombacher, F.3
  • 12
    • 0031159107 scopus 로고    scopus 로고
    • Impaired macrophage listericidal and cytokine activities are responsible for the rapid death of Listeria monocytogenes-infected IFN-gamma receptor-deficient mice
    • Dai, W. J., W. Bartens, G. Kohler, M. Hufnagel, M. Kopf, and F. Brombacher. 1997. Impaired macrophage listericidal and cytokine activities are responsible for the rapid death of Listeria monocytogenes-infected IFN-gamma receptor-deficient mice. J. Immunol. 158:5297-5304.
    • (1997) J. Immunol. , vol.158 , pp. 5297-5304
    • Dai, W.J.1    Bartens, W.2    Kohler, G.3    Hufnagel, M.4    Kopf, M.5    Brombacher, F.6
  • 14
    • 0030896666 scopus 로고    scopus 로고
    • Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis
    • Fehr, T., G. Schoedon, B. Odermatt, T. Holtschke, M. Schneemann, M. F. Bachmann, T. W. Mak, I. Horak, and R. M. Zinkernagel. 1997. Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis. J. Exp. Med. 185:921-931.
    • (1997) J. Exp. Med. , vol.185 , pp. 921-931
    • Fehr, T.1    Schoedon, G.2    Odermatt, B.3    Holtschke, T.4    Schneemann, M.5    Bachmann, M.F.6    Mak, T.W.7    Horak, I.8    Zinkernagel, R.M.9
  • 15
    • 0021360012 scopus 로고
    • Acyltransferase-catalyzed cleavage of arachidonic acid from phospholipids and transfer to lysophosphatides in macrophages derived from bone marrow. Comparison of different donor-and acceptor substrate combinations
    • Flesch, I., B. Ecker, and E. Ferber. 1984. Acyltransferase-catalyzed cleavage of arachidonic acid from phospholipids and transfer to lysophosphatides in macrophages derived from bone marrow. Comparison of different donor-and acceptor substrate combinations. Eur. J. Biochem. 139:431-437.
    • (1984) Eur. J. Biochem. , vol.139 , pp. 431-437
    • Flesch, I.1    Ecker, B.2    Ferber, E.3
  • 16
    • 0030472258 scopus 로고    scopus 로고
    • Trypanosoma cruzi is a potent inducer of interleukin-12 production in macrophages
    • Frosch, S., S. Kraus, and B. Fleischer. 1996. Trypanosoma cruzi is a potent inducer of interleukin-12 production in macrophages. Med. Microbiol. Immunol. 185:189-193.
    • (1996) Med. Microbiol. Immunol. , vol.185 , pp. 189-193
    • Frosch, S.1    Kraus, S.2    Fleischer, B.3
  • 17
    • 0027264849 scopus 로고
    • Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts
    • Gazzinelli, R. T., S. Hieny, T. A. Wynn, S. Wolf, and A. Sher. 1993. Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts. Proc. Natl. Acad. Sci. USA 90:6115-6119.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6115-6119
    • Gazzinelli, R.T.1    Hieny, S.2    Wynn, T.A.3    Wolf, S.4    Sher, A.5
  • 18
    • 0026529405 scopus 로고
    • IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages
    • Gazzinelli, R. T., I. P. Oswald, S. L, James, and A. Sher. 1992. IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages. J. Immunol. 148:1792-1796.
    • (1992) J. Immunol. , vol.148 , pp. 1792-1796
    • Gazzinelli, R.T.1    Oswald, I.P.2    James, S.L.3    Sher, A.4
  • 19
    • 0026165320 scopus 로고
    • Trypanosoma cruzi: Cytokine effects on macrophage trypanocidal activity
    • Golden, J. M., and R. L. Tarleton. 1991. Trypanosoma cruzi: cytokine effects on macrophage trypanocidal activity. Exp. Parasitol. 72:391-402.
    • (1991) Exp. Parasitol. , vol.72 , pp. 391-402
    • Golden, J.M.1    Tarleton, R.L.2
  • 20
    • 0027336689 scopus 로고
    • Development of T(H)1 CD4(+) T cells through IL-12 produced by Listeria-induced macrophages
    • Hsieh, C. S., S. E. Macatonia, C. S. Tripp, S. F. Wolf, A. O'Garra, and K. M. Murphy. 1993. Development of T(H)1 CD4(+) T cells through IL-12 produced by Listeria-induced macrophages. Science 260:547-549.
    • (1993) Science , vol.260 , pp. 547-549
    • Hsieh, C.S.1    Macatonia, S.E.2    Tripp, C.S.3    Wolf, S.F.4    O'Garra, A.5    Murphy, K.M.6
  • 26
    • 0008953208 scopus 로고    scopus 로고
    • Evidence for a protective role of tumor necrosis factor in the acute phase of Trypanosoma cruzi infection in mice
    • Lima, E. C. S., I. Garcia, M.-H. Vicentelli, P. Vassalli, and P. Minoprio. 1997. Evidence for a protective role of tumor necrosis factor in the acute phase of Trypanosoma cruzi infection in mice. Infect. Immun. 65:457-465.
    • (1997) Infect. Immun. , vol.65 , pp. 457-465
    • Lima, E.C.S.1    Garcia, I.2    Vicentelli, M.-H.3    Vassalli, P.4    Minoprio, P.5
  • 27
    • 0028324939 scopus 로고
    • Trypanosoma cruzi-induced immunosuppression: Blockade of costimulatory T-cell responses in infected hosts due to defective T-cell receptor-CD3 functioning
    • Lopes, M. F., and G. A. Dos Reis. 1994. Trypanosoma cruzi-induced immunosuppression: blockade of costimulatory T-cell responses in infected hosts due to defective T-cell receptor-CD3 functioning. Infect. Immun. 62:1484-1488.
    • (1994) Infect. Immun. , vol.62 , pp. 1484-1488
    • Lopes, M.F.1    Dos Reis, G.A.2
  • 29
    • 0025759064 scopus 로고
    • Endogenous interferon-gamma, macrophage activation, and murine host defense against acute infection with Trypanosoma cruzi
    • McCabe, R. E., S. G. Meagher, and B. T. Mullins. 1991. Endogenous interferon-gamma, macrophage activation, and murine host defense against acute infection with Trypanosoma cruzi. J. Infect. Dis. 163:912-915.
    • (1991) J. Infect. Dis. , vol.163 , pp. 912-915
    • McCabe, R.E.1    Meagher, S.G.2    Mullins, B.T.3
  • 30
    • 0025858885 scopus 로고
    • Differential control of IFN-gamma and IL-2 production during Trypanosoma cruzi infection
    • Nabors, G. S., and R. L. Tarleton. 1991. Differential control of IFN-gamma and IL-2 production during Trypanosoma cruzi infection. J. Immunol. 146: 3591-3598.
    • (1991) J. Immunol. , vol.146 , pp. 3591-3598
    • Nabors, G.S.1    Tarleton, R.L.2
  • 31
    • 0028286134 scopus 로고
    • Release of nitric oxide during the experimental infection with Trypanosoma cruzi
    • Petray, P., M. E. Rottenberg, S. Grinstein, and A. Orn. 1994. Release of nitric oxide during the experimental infection with Trypanosoma cruzi. Parasite Immunol. 16:193-199.
    • (1994) Parasite Immunol. , vol.16 , pp. 193-199
    • Petray, P.1    Rottenberg, M.E.2    Grinstein, S.3    Orn, A.4
  • 32
    • 0025874048 scopus 로고
    • Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of Superoxide and nitric oxide
    • Radi, R., J. S. Beckman, K. M. Bush, and B. A. Freeman. 1991. Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of Superoxide and nitric oxide. Arch. Biochem. Biophys. 288:481-487.
    • (1991) Arch. Biochem. Biophys. , vol.288 , pp. 481-487
    • Radi, R.1    Beckman, J.S.2    Bush, K.M.3    Freeman, B.A.4
  • 33
    • 0023770735 scopus 로고
    • In vivo administration of recombinant IFN-gamma induces macrophage activation and prevents acute disease, immune suppression, and death in experimental Trypanosoma cruzi infections
    • Reed, S. G. 1988. In vivo administration of recombinant IFN-gamma induces macrophage activation and prevents acute disease, immune suppression, and death in experimental Trypanosoma cruzi infections. J. Immunol. 140:4342-4347.
    • (1988) J. Immunol. , vol.140 , pp. 4342-4347
    • Reed, S.G.1
  • 34
    • 0024521586 scopus 로고
    • Immune deficiency in chronic Trypanosoma cruzi infection. Recombinant IL-1 restores Th function for antibody production
    • Reed, S. G., D. L. Pihl, and K. H. Grabstein. 1989. Immune deficiency in chronic Trypanosoma cruzi infection. Recombinant IL-1 restores Th function for antibody production. J. Immunol. 142:2067-2071.
    • (1989) J. Immunol. , vol.142 , pp. 2067-2071
    • Reed, S.G.1    Pihl, D.L.2    Grabstein, K.H.3
  • 35
    • 0028341384 scopus 로고
    • Tumor necrosis factor and interleukin-1 synergy in the context of malaria pathology
    • Rockett, K. A., M. M. Awburn, E. J. Rockett, and I. A. Clark. 1994. Tumor necrosis factor and interleukin-1 synergy in the context of malaria pathology. Am. J. Trop. Med. Hyg. 50:735-742.
    • (1994) Am. J. Trop. Med. Hyg. , vol.50 , pp. 735-742
    • Rockett, K.A.1    Awburn, M.M.2    Rockett, E.J.3    Clark, I.A.4
  • 36
    • 0024406861 scopus 로고
    • Modulation of both interleukin 2 receptor expression and interleukin 2 production during experimental murine Trypanosoma cruzi infection
    • Rottenberg, M., C. Lindqvist, A. Koman, E. L. Segura, and A. Orn. 1989. Modulation of both interleukin 2 receptor expression and interleukin 2 production during experimental murine Trypanosoma cruzi infection. Scand. J. Immunol. 30:65-72.
    • (1989) Scand. J. Immunol. , vol.30 , pp. 65-72
    • Rottenberg, M.1    Lindqvist, C.2    Koman, A.3    Segura, E.L.4    Orn, A.5
  • 37
    • 0029820843 scopus 로고    scopus 로고
    • Intracellular co-localization of Trypanosoma cruzi and inducible nitric oxide synthase (iNOS): Evidence for dual pathway of iNOS induction
    • Rottenberg, M. E., E, Castanos-Velez, R. de Mesquita, O. G. Laguardia, P. Biberfeld, and A. Orn. 1996. Intracellular co-localization of Trypanosoma cruzi and inducible nitric oxide synthase (iNOS): evidence for dual pathway of iNOS induction. Eur. J. Immunol. 26:3203-3213.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 3203-3213
    • Rottenberg, M.E.1    Castanos-Velez, E.2    De Mesquita, R.3    Laguardia, O.G.4    Biberfeld, P.5    Orn, A.6
  • 38
    • 0023938675 scopus 로고
    • Parasitic load increases and myocardial inflammation decreases in Trypanosoma cruzi-infected mice after inactivation of helper T cells
    • Russo, M., N. Starobinas, P. Minoprio, A. Coutinho, and M. Hontebeyrie-Joskowicz. 1988. Parasitic load increases and myocardial inflammation decreases in Trypanosoma cruzi-infected mice after inactivation of helper T cells. Ann. Inst. Pasteur Immunol. 139:225-236.
    • (1988) Ann. Inst. Pasteur Immunol. , vol.139 , pp. 225-236
    • Russo, M.1    Starobinas, N.2    Minoprio, P.3    Coutinho, A.4    Hontebeyrie-Joskowicz, M.5
  • 39
    • 0030294163 scopus 로고    scopus 로고
    • In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection
    • Scharton, K. T., T. A. Wynn, E. Y. Denkers, S. Bala, E. Grunvald, S. Hieny, R. T. Gazzinelli, and A. Sher. 1996. In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection. J. Immunol. 157:4045-4054.
    • (1996) J. Immunol. , vol.157 , pp. 4045-4054
    • Scharton, K.T.1    Wynn, T.A.2    Denkers, E.Y.3    Bala, S.4    Grunvald, E.5    Hieny, S.6    Gazzinelli, R.T.7    Sher, A.8
  • 40
    • 0030970867 scopus 로고    scopus 로고
    • Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii
    • Scharton-Kersten, T. M., G. Yap, J. Magram, and A. Sher. 1997. Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii. J. Exp. Med. 185:1261-1273.
    • (1997) J. Exp. Med. , vol.185 , pp. 1261-1273
    • Scharton-Kersten, T.M.1    Yap, G.2    Magram, J.3    Sher, A.4
  • 41
    • 0023197097 scopus 로고
    • Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production
    • Snapper, C. M., and W. E. Paul. 1987. Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production. Science 236:944-947.
    • (1987) Science , vol.236 , pp. 944-947
    • Snapper, C.M.1    Paul, W.E.2
  • 42
    • 0029976423 scopus 로고    scopus 로고
    • Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase
    • Stenger, S., N. Donhauser, H. Thuring, M. Rollinghoff, and C. Bogdan. 1996. Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase. J. Exp. Med. 183:1501-1514.
    • (1996) J. Exp. Med. , vol.183 , pp. 1501-1514
    • Stenger, S.1    Donhauser, N.2    Thuring, H.3    Rollinghoff, M.4    Bogdan, C.5
  • 43
    • 0025117462 scopus 로고
    • Depletion of CD8+ T cells increases susceptibility and reverses vaccine-induced immunity in mice infected with Trypanosoma cruzi
    • Tarleton, R. L. 1990. Depletion of CD8+ T cells increases susceptibility and reverses vaccine-induced immunity in mice infected with Trypanosoma cruzi. J. Immunol. 144:717-724.
    • (1990) J. Immunol. , vol.144 , pp. 717-724
    • Tarleton, R.L.1
  • 45
    • 0025829971 scopus 로고
    • Endogenous IFN-gamma is required for resistance to acute Trypanosoma cruzi infection in mice
    • Torrico, F., H. Heremans, M. T. Rivera, E. Van Marck, A. Billiau, and Y. Carlier. 1991. Endogenous IFN-gamma is required for resistance to acute Trypanosoma cruzi infection in mice. J. Immunol. 146:3626-3632.
    • (1991) J. Immunol. , vol.146 , pp. 3626-3632
    • Torrico, F.1    Heremans, H.2    Rivera, M.T.3    Van Marck, E.4    Billiau, A.5    Carlier, Y.6
  • 47
    • 0028051548 scopus 로고
    • Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro
    • Vespa, G. N., F. Q. Cunha, and J. S. Silva. 1994. Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro. Infect. Immun. 62:5177-5182.
    • (1994) Infect. Immun. , vol.62 , pp. 5177-5182
    • Vespa, G.N.1    Cunha, F.Q.2    Silva, J.S.3
  • 49
    • 0029128121 scopus 로고
    • Dissection of strain difference in acquired protective immunity against Mycobacterium bovis Calmette-Guerin bacillus (BCG). Macrophages regulate the susceptibility through cytokine network and the induction of nitric oxide synthase
    • Yoshida, A., Y. Koide, M. Uchijima, and T. O. Yoshida. 1995. Dissection of strain difference in acquired protective immunity against Mycobacterium bovis Calmette-Guerin bacillus (BCG). Macrophages regulate the susceptibility through cytokine network and the induction of nitric oxide synthase. J. Immunol. 155:2057-2066.
    • (1995) J. Immunol. , vol.155 , pp. 2057-2066
    • Yoshida, A.1    Koide, Y.2    Uchijima, M.3    Yoshida, T.O.4


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