Effects of HO-/MeO-PBDEs on androgen receptor: In vitro investigation and helix 12-involved MD simulation

Environmental Science and Technology

Volumn 47, Issue 20, 2013, Pages 11802-11809

  Wang, Xiaoxiang ^a   Yang, Huaiyu ^b   Hu, Xinxin ^a   Zhang, Xiaowei ^a   Zhang, Qiansen ^b   Jiang, Hualiang ^b   Shi, Wei ^a   Yu, Hongxia ^a  

^a NANJING UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGENIC ACTIVITY; COMPUTATIONAL SIMULATION; CONFORMATIONAL TRANSITIONS; ENDOCRINE DISRUPTING ACTIVITY; ENVIRONMENTAL DISTRIBUTION; ENVIRONMENTAL POLLUTANTS; METHOXYLATED POLYBROMINATED DIPHENYL ETHERSS; MOLECULAR DYNAMICS SIMULATIONS;

CELL CULTURE; METABOLITES; MOLECULAR DYNAMICS; ORGANIC POLLUTANTS;

LIGANDS;

ANDROGEN RECEPTOR; DIPHENYL ETHER DERIVATIVE;

ANDROGEN; BIOASSAY; COMPUTER SIMULATION; ENDOCRINE DISRUPTOR; ETHER; LIGAND; MOLECULAR ANALYSIS; NUMERICAL MODEL; PBDE;

ARTICLE; BROMINATION; CONFORMATIONAL TRANSITION; HYDROXYLATION; MOLECULAR DYNAMICS; SIMULATION;

ANDROGEN RECEPTOR ANTAGONISTS; CELL LINE; FLUTAMIDE; GENES, REPORTER; HALOGENATED DIPHENYL ETHERS; HUMANS; HYDROXYLATION; LIGANDS; MOLECULAR DYNAMICS SIMULATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ANDROGEN; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS;

EID: 84886896376     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es4029364     Document Type: Article

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