Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells

Environmental Health Perspectives

Volumn 117, Issue 8, 2009, Pages 1210-1218

  Kojima, Hiroyuki ^a   Takeuchi, Shinji ^a   Uramaru, Naoto ^b,c   Sugihara, Kazumi ^b   Yoshida, Takahiko ^d   Kitamura, Shigeyuki ^c  

^a HOKKAIDO INSTITUTE OF PUBLIC HEALTH   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c NIHON PHARMACEUTICAL UNIVERSITY   (Japan)

^d ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

Androgen receptor; Brominated diphenyl ether; Chinese hamster ovary cells; Estrogen receptor; Glucocorticoid receptor; Reporter gene assay; Thyroid hormone receptor

Indexed keywords

ANDROGEN RECEPTOR; ENDOCRINE DISRUPTOR; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GLUCOCORTICOID RECEPTOR; HORMONE RECEPTOR; POLYBROMINATED DIPHENYL ETHER; THYROID HORMONE RECEPTOR ALPHA; THYROID HORMONE RECEPTOR BETA;

ANIMAL CELL; ARTICLE; CHEMICAL STRUCTURE; CHO CELL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ESTROGEN ACTIVITY; FEMALE; GENETIC TRANSCRIPTION; HYDROXYLATION; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BLOCKING; REPORTER GENE; TRANSACTIVATION;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; HALOGENATED DIPHENYL ETHERS; HUMANS; MOLECULAR STRUCTURE; RECEPTORS, ANDROGEN; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, GLUCOCORTICOID; THYROID HORMONE RECEPTORS ALPHA; THYROID HORMONE RECEPTORS BETA;

CRICETULUS GRISEUS;

EID: 69249109660     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.0900753     Document Type: Article

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