In vitro profiling of endocrine disrupting potency of 2,2′,4,4′-tetrabromodiphenyl ether (BDE47) and related hydroxylated analogs (HO-PBDEs)

Marine Pollution Bulletin

Volumn 63, Issue 5-12, 2011, Pages 287-296

  Liu, Hongling ^a   Hu, Wei ^a   Sun, Hong ^b   Shen, Ouxi ^b   Wang, Xinru ^b   Lam, Michael H W ^c   Giesy, John P ^a,c,d,e   Zhang, Xiaowei ^a   Yu, Hongxia ^a  

^a NANJING UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c CITY UNIVERSITY OF HONG KONG   (Hong Kong)

^d UNIVERSITY OF SASKATCHEWAN   (Canada)

^e MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

BDE47; Endocrine disruption; Metabolite; Receptor reporter gene assay

Indexed keywords

ANTI-ANDROGENIC; ANTI-ESTROGENIC; BDE47; ENDOCRINE DISRUPTION; IN-VITRO; REPORTER GENE ASSAYS; TRANSCRIPTIONAL ACTIVITY;

ASSAYS; ETHERS; GENES; HYDROXYLATION;

ORGANIC COMPOUNDS;

2,2',4,4' TETRABROMODIPHENYLETHER; ANDROGEN RECEPTOR; ENDOCRINE DISRUPTOR; ESTROGEN RECEPTOR; POLYBROMINATED DIPHENYL ETHER; THYROID HORMONE RECEPTOR; UNCLASSIFIED DRUG;

BIOASSAY; ENDOCRINE DISRUPTOR; ESTROGENIC COMPOUND; GENE EXPRESSION; HYDROXYL RADICAL; METABOLITE; OBSERVATIONAL METHOD;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENETIC TRANSFECTION; HORMONE RESPONSE; HYDROXYLATION; IC 50; IN VITRO STUDY; NONHUMAN; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; ANTITHYROID AGENTS; CELL LINE; CELL SURVIVAL; ENDOCRINE DISRUPTORS; HALOGENATED DIPHENYL ETHERS; HAPLORHINI; HYDROXYLATION; WATER POLLUTANTS, CHEMICAL;

EID: 79960381371     PISSN: 0025326X     EISSN: 18793363     Source Type: Journal    
DOI: 10.1016/j.marpolbul.2011.04.019     Document Type: Article

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