The OSIRIS Weight of Evidence approach: ITS for skin sensitisation

Regulatory Toxicology and Pharmacology

Volumn 67, Issue 2, 2013, Pages 146-156

  Rorije, Emiel ^a   Aldenberg, Tom ^a   Buist, Harrie ^b   Kroese, Dinant ^b   Schüürmann, Gerrit ^c,d  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b TNO   (Netherlands)

^c HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

^d TU BERGAKADEMIE FREIBERG   (Germany)

Author keywords

Bayesian inference; Integrated Testing Strategy; ITS; REACH; Weight of Evidence; WoE

Indexed keywords

ANALYTIC METHOD; ARTICLE; BAYES THEOREM; CARCINOGENICITY; COMPUTER PROGRAM; HUMAN; LAW; MUTAGENICITY; OSIRIS; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RELIABILITY; REPRODUCIBILITY; RISK ASSESSMENT; SKIN SENSITIZATION; TOXICOLOGY;

ANIMALIA;

BAYESIAN INFERENCE; INTEGRATED TESTING STRATEGY; ITS; REACH; WEIGHT-OF-EVIDENCE; WOE;

ANIMAL TESTING ALTERNATIVES; BAYES THEOREM; DERMATITIS, CONTACT; HAZARDOUS SUBSTANCES; MODELS, STATISTICAL; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RISK ASSESSMENT; SKIN IRRITANCY TESTS;

EID: 84886582869     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2013.06.003     Document Type: Article

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