Prediction of skin sensitization potency of chemicals by human Cell Line Activation Test (h-CLAT) and an attempt at classifying skin sensitization potency

Toxicology in Vitro

Volumn 26, Issue 7, 2012, Pages 1150-1160

  Nukada, Yuko ^a   Ashikaga, Takao ^b   Miyazawa, Masaaki ^a   Hirota, Morihiko ^b   Sakaguchi, Hitoshi ^a   Sasa, Hitoshi ^b   Nishiyama, Naohiro ^a  

^a KAO CORPORATION   (Japan)

^b SHISEIDO RESEARCH CENTER   (Japan)

Author keywords

Alternative; h CLAT; MIT; Potency categorization; Risk assessment; Skin sensitization

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 1 NAPHTHOL; 1,4 BENZOQUINONE; 2 AMINOPHENOL; 2 BROMO 2 BROMOMETHYLGLUTARONITRILE; 2 MERCAPTOBENZOTHIAZOLE; 3 AMINOPHENOL; BENZOYL PEROXIDE; BENZYL BROMIDE; BENZYLIDENEACETONE; CD86 ANTIGEN; CINNAMALDEHYDE; COBALT CHLORIDE; DICHROMATE POTASSIUM; DIETHYL SULFATE; DIPHENCYPRONE; DODECYL GALLATE; ETHYLENEDIAMINE; FORMALDEHYDE; GALLIC ACID PROPYL ESTER; GLUTARALDEHYDE; GLYOXAL; INTERCELLULAR ADHESION MOLECULE 1; ISOEUGENOL; MALEIC ANHYDRIDE; OXAZOLONE; PHENYLENEDIAMINE; PHTHALIC ANHYDRIDE; TOSYLCHLORAMIDE SODIUM;

ANALYTICAL PARAMETERS; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CORRELATION ANALYSIS; DATA ANALYSIS; DIAGNOSTIC ACCURACY; DIFFERENTIAL DIAGNOSIS; HUMAN; HUMAN CELL; HUMAN CELL LINE ACTIVATION TEST; IN VITRO STUDY; LABORATORY TEST; LOCAL LYMPH NODE ASSAY; MATHEMATICAL COMPUTING; MINIMUM INDUCTION THRESHOLD; MULTIPLE CHEMICAL SENSITIVITY; PREDICTIVE VALUE; PROTEIN EXPRESSION; RISK ASSESSMENT; SKIN ALLERGY; SKIN SENSITIZATION;

ALLERGENS; ANIMAL TESTING ALTERNATIVES; CELL LINE, TUMOR; CELL SURVIVAL; DERMATITIS, CONTACT; HUMANS; HYPERSENSITIVITY; LOCAL LYMPH NODE ASSAY; MONOCYTES; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; SKIN IRRITANCY TESTS;

EID: 84866053372     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2012.07.001     Document Type: Article

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