OSIRIS, a quest for proof of principle for integrated testing strategies of chemicals for four human health endpoints

Regulatory Toxicology and Pharmacology

Volumn 67, Issue 2, 2013, Pages 136-145

  Vermeire, Theo ^a   Aldenberg, Tom ^a   Buist, Harrie ^b   Escher, Sylvia ^c   Mangelsdorf, Inge ^c   Pauné, Eduard ^d   Rorije, Emiel ^a   Kroese, Dinant ^b  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b TNO   (Netherlands)

^c FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

^d SIMPPLE   (Spain)

Author keywords

3R; Data quality; Exposure Based Waiving; Integrated testing strategy; ITS; REACH; Weight of Evidence

Indexed keywords

ARTICLE; CARCINOGENICITY; EUROPEAN UNION; EXPOSURE; INFORMATION PROCESSING; INTEGRATED TESTING STRATEGIES; LAW; MUTAGENICITY; PRIORITY JOURNAL; QUALITY CONTROL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RISK ASSESSMENT; SKIN SENSITIZATION; TOXICITY TESTING; VALIDITY;

ANIMALIA;

3R; DATA QUALITY; EXPOSURE-BASED WAIVING; INTEGRATED TESTING STRATEGY; ITS; REACH; WEIGHT OF EVIDENCE;

ANIMAL TESTING ALTERNATIVES; ANIMALS; HAZARDOUS SUBSTANCES; HUMANS; RISK ASSESSMENT; TOXICITY TESTS;

EID: 84886598976     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2013.01.007     Document Type: Article

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