메뉴 건너뛰기




Volumn , Issue , 2010, Pages 273-290

Drug Interactions with St. John's Wort

Author keywords

Drug interactions drug interactions with St. John's Wort; Hyperforin role in CYP3A induction by SJW studies, showing CYP3A induction, influenced by hyperforin content; St. John's Wort in treating depression

Indexed keywords


EID: 84886008895     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470910108.ch12     Document Type: Chapter
Times cited : (1)

References (125)
  • 1
    • 0031833102 scopus 로고    scopus 로고
    • Phytochemical characterization of various St. John's wort extracts
    • Kurth H, Spreemann R. Phytochemical characterization of various St. John's wort extracts. Adv Ther 1998; 15: 117-28.
    • (1998) Adv Ther , vol.15 , pp. 117-128
    • Kurth, H.1    Spreemann, R.2
  • 3
    • 0031730282 scopus 로고    scopus 로고
    • Scientifi c and regulatory aspects of nutraceutical products in the United States
    • Kottke MK. Scientifi c and regulatory aspects of nutraceutical products in the United States. Drug Dev Ind Pharm 1998; 24: 1177-95.
    • (1998) Drug Dev Ind Pharm , vol.24 , pp. 1177-1195
    • Kottke, M.K.1
  • 4
    • 0034707701 scopus 로고    scopus 로고
    • St John's wort for depression: a systematic review
    • Gaster B, Holroyd J. St John's wort for depression: a systematic review. Arch Intern Med 2000; 160: 152-6.
    • (2000) Arch Intern Med , vol.160 , pp. 152-156
    • Gaster, B.1    Holroyd, J.2
  • 6
    • 0035899915 scopus 로고    scopus 로고
    • Herbal medicines today and the roots of modern pharmacology
    • Goldman P. Herbal medicines today and the roots of modern pharmacology. Ann Intern Med 2001; 135: 594-600.
    • (2001) Ann Intern Med , vol.135 , pp. 594-600
    • Goldman, P.1
  • 8
    • 84872773879 scopus 로고    scopus 로고
    • Complementary and alternative medicine use among adults and children: United States, 2007
    • Barnes PM, Bloom B, Nahin RL. Complementary and alternative medicine use among adults and children: United States, 2007. Natl Health Stat Report (CDC) 2008; 12: 1-24.
    • (2008) Natl Health Stat Report (CDC) , vol.12 , pp. 1-24
    • Barnes, P.M.1    Bloom, B.2    Nahin, R.L.3
  • 10
    • 0032824062 scopus 로고    scopus 로고
    • The experimental and clinical pharmacology of St John's wort (Hypericum perforatum L.)
    • Nathan P. The experimental and clinical pharmacology of St John's wort (Hypericum perforatum L.). Mol Psychiatry 1999; 4: 333-8.
    • (1999) Mol Psychiatry , vol.4 , pp. 333-338
    • Nathan, P.1
  • 11
    • 26644462876 scopus 로고    scopus 로고
    • SNRIs: their pharmacology, clinical effi cacy, and tolerability in comparison with other classes of antidepressants
    • Stahl SM, Grady MM, Moret C, Briley M. SNRIs: their pharmacology, clinical effi cacy, and tolerability in comparison with other classes of antidepressants. CNS Spectr 2005; 10: 732-47.
    • (2005) CNS Spectr , vol.10 , pp. 732-747
    • Stahl, S.M.1    Grady, M.M.2    Moret, C.3    Briley, M.4
  • 13
    • 14644387614 scopus 로고    scopus 로고
    • Usefulness of studies on the molecular mechanism of action of herbals/botanicals: the case of St. John's wort
    • Choudhuri S, Valerio LG, Jr. Usefulness of studies on the molecular mechanism of action of herbals/botanicals: the case of St. John's wort. J Biochem Mol Toxicol 2005; 19: 1-11.
    • (2005) J Biochem Mol Toxicol , vol.19 , pp. 1-11
    • Choudhuri, S.1    Valerio Jr., L.G.2
  • 14
    • 0000006828 scopus 로고    scopus 로고
    • Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum)
    • Johne A, Brockmoller J, Bauer S, Maurer A, Langheinrich M, Roots I. Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum). Clin Pharmacol Ther 1999; 66: 338-45.
    • (1999) Clin Pharmacol Ther , vol.66 , pp. 338-345
    • Johne, A.1    Brockmoller, J.2    Bauer, S.3    Maurer, A.4    Langheinrich, M.5    Roots, I.6
  • 17
    • 0034720558 scopus 로고    scopus 로고
    • Profound drop of cyclosporin A whole blood trough levels caused by St. John's wort (Hypericum perforatum)
    • Breidenbach T, Kliem V, Burg M, Radermacher J, Hoffmann MW, Klempnauer J. Profound drop of cyclosporin A whole blood trough levels caused by St. John's wort (Hypericum perforatum). Transplantation 2000. 69: 2229-30.
    • (2000) Transplantation , vol.69 , pp. 2229-2230
    • Breidenbach, T.1    Kliem, V.2    Burg, M.3    Radermacher, J.4    Hoffmann, M.W.5    Klempnauer, J.6
  • 19
    • 0034638002 scopus 로고    scopus 로고
    • St John's wort interaction with digoxin
    • Cheng TO. St John's wort interaction with digoxin. Arch Intern Med 2000; 160: 2548.
    • (2000) Arch Intern Med , vol.160 , pp. 2548
    • Cheng, T.O.1
  • 20
    • 0033763121 scopus 로고    scopus 로고
    • Interaction of Hypericum perforatum (St. John's wort) with cyclosporin A metabolism in a patient after liver transplantation
    • Karliova M, Treichel U, Malago M, Frilling A, Gerken G, Broelsch CE. Interaction of Hypericum perforatum (St. John's wort) with cyclosporin A metabolism in a patient after liver transplantation. J Hepatol 2000; 33: 853-5.
    • (2000) J Hepatol , vol.33 , pp. 853-855
    • Karliova, M.1    Treichel, U.2    Malago, M.3    Frilling, A.4    Gerken, G.5    Broelsch, C.E.6
  • 21
    • 0033787159 scopus 로고    scopus 로고
    • Hazardous pharmacokinetic interaction of Saint John's wort (Hypericum perforatum) with the immunosuppressant cyclosporin
    • Mai I, Kruger H, Budde K, Johne A, Brockmoller J, Neumayer HH, Roots I. Hazardous pharmacokinetic interaction of Saint John's wort (Hypericum perforatum) with the immunosuppressant cyclosporin. Int J Clin Pharmacol Ther 2000; 38: 500-2.
    • (2000) Int J Clin Pharmacol Ther , vol.38 , pp. 500-502
    • Mai, I.1    Kruger, H.2    Budde, K.3    Johne, A.4    Brockmoller, J.5    Neumayer, H.H.6    Roots, I.7
  • 25
    • 0034935316 scopus 로고    scopus 로고
    • Low cyclosporin-A level due to Saint John's wort in heart transplant patients
    • Ahmed SM, Banner NR, Dubrey SW. Low cyclosporin-A level due to Saint John's wort in heart transplant patients. J Heart Lung Transplant 2001; 20: 795.
    • (2001) J Heart Lung Transplant , vol.20 , pp. 795
    • Ahmed, S.M.1    Banner, N.R.2    Dubrey, S.W.3
  • 26
    • 0034749903 scopus 로고    scopus 로고
    • Interaction between cyclosporine and Hypericum perforatum (St. John's wort) after organ transplantation
    • Moschella C, Jaber BL. Interaction between cyclosporine and Hypericum perforatum (St. John's wort) after organ transplantation. Am J Kidney Dis 2001; 38: 1105-7.
    • (2001) Am J Kidney Dis , vol.38 , pp. 1105-1107
    • Moschella, C.1    Jaber, B.L.2
  • 27
    • 0029584276 scopus 로고
    • Substrates of human hepatic cytochrome P450 3A4
    • Li AP, Kaminski DL, Rasmussen A. Substrates of human hepatic cytochrome P450 3A4. Toxicology 1995; 104: 1-8.
    • (1995) Toxicology , vol.104 , pp. 1-8
    • Li, A.P.1    Kaminski, D.L.2    Rasmussen, A.3
  • 29
    • 0014897392 scopus 로고
    • Resistance to various pesticides induced by catatoxic steroids
    • Selye H. Resistance to various pesticides induced by catatoxic steroids. Arch Environ Health 1970; 21: 706-10.
    • (1970) Arch Environ Health , vol.21 , pp. 706-710
    • Selye, H.1
  • 30
    • 84986674938 scopus 로고
    • Hormones and resistance
    • Selye H. Hormones and resistance. J Pharm Sci 1971; 60: 1-28.
    • (1971) J Pharm Sci , vol.60 , pp. 1-28
    • Selye, H.1
  • 31
    • 0016186707 scopus 로고
    • Comparative studies on the effect of adrenocorticotrophic hormone (ACTH) and pregnenolone-16alpha-carbonitrile (PCN) upon drug response and distribution in rats
    • Szabo S, Selye H, Kourounakis P, Tache Y. Comparative studies on the effect of adrenocorticotrophic hormone (ACTH) and pregnenolone-16alpha-carbonitrile (PCN) upon drug response and distribution in rats. Biochem Pharmacol 1974; 23: 2083-94.
    • (1974) Biochem Pharmacol , vol.23 , pp. 2083-2094
    • Szabo, S.1    Selye, H.2    Kourounakis, P.3    Tache, Y.4
  • 32
    • 50549210104 scopus 로고
    • Factors Affecting hepatic microsomal enzyme systems involved in drug metabolism
    • Fouts JR. Factors Affecting hepatic microsomal enzyme systems involved in drug metabolism. Adv Enzyme Regul 1963; 1: 225-33.
    • (1963) Adv Enzyme Regul , vol.1 , pp. 225-233
    • Fouts, J.R.1
  • 33
    • 0015502470 scopus 로고
    • Unplanned pregnancy in an epileptic
    • Kenyon IE. Unplanned pregnancy in an epileptic. Br Med J 1972; 1: 686-7.
    • (1972) Br Med J , vol.1 , pp. 686-687
    • Kenyon, I.E.1
  • 34
    • 0017186603 scopus 로고
    • Letter: oral contraceptive failure due to drug interaction
    • Dommisse J. Letter: oral contraceptive failure due to drug interaction. S Afr Med J 1976; 50: 796.
    • (1976) S Afr Med J , vol.50 , pp. 796
    • Dommisse, J.1
  • 36
    • 0017601139 scopus 로고
    • Interaction of rifampicin treatment with pharmacokinetics and metabolism of ethinyloestradiol in man
    • Bolt HM, Bolt M, Kappus H. Interaction of rifampicin treatment with pharmacokinetics and metabolism of ethinyloestradiol in man. Acta Endocrinol (Copenh) 1977; 85: 189-97.
    • (1977) Acta Endocrinol (Copenh) , vol.85 , pp. 189-197
    • Bolt, H.M.1    Bolt, M.2    Kappus, H.3
  • 37
    • 0017792816 scopus 로고
    • Drug interaction with oral contraceptives
    • Hillier K. Drug interaction with oral contraceptives. Fertil Contracept 1978; 2: 5-8.
    • (1978) Fertil Contracept , vol.2 , pp. 5-8
    • Hillier, K.1
  • 41
    • 0021941863 scopus 로고
    • Acute rejection and massive cyclosporine requirements in heart transplant recipients treated with rifampin
    • Modry DL, Stinson EB, Oyer PE, Jamieson SW, Baldwin JC, Shumway NE. Acute rejection and massive cyclosporine requirements in heart transplant recipients treated with rifampin. Transplantation 1985; 39: 313-4.
    • (1985) Transplantation , vol.39 , pp. 313-314
    • Modry, D.L.1    Stinson, E.B.2    Oyer, P.E.3    Jamieson, S.W.4    Baldwin, J.C.5    Shumway, N.E.6
  • 42
    • 0022642140 scopus 로고
    • Effect of phenobarbital and cimetidine on experimental cyclosporine nephrotoxicity: preliminary observations
    • Schwass DE, Sasaki AW, Houghton DC, Benner KE, Bennett WM. Effect of phenobarbital and cimetidine on experimental cyclosporine nephrotoxicity: preliminary observations. Clin Nephrol 1986; 25 (Suppl 1): S117-20.
    • (1986) Clin Nephrol , vol.25 , Issue.SUPPL. 1
    • Schwass, D.E.1    Sasaki, A.W.2    Houghton, D.C.3    Benner, K.E.4    Bennett, W.M.5
  • 44
    • 0027320543 scopus 로고
    • The multidrug resistance P-glycoprotein
    • Higgins CF. The multidrug resistance P-glycoprotein. Curr Opin Cell Biol 1993; 5: 684-7.
    • (1993) Curr Opin Cell Biol , vol.5 , pp. 684-687
    • Higgins, C.F.1
  • 45
    • 0036229852 scopus 로고    scopus 로고
    • Drugs as P-glycoprotein substrates, inhibitors, and inducers
    • Kim RB. Drugs as P-glycoprotein substrates, inhibitors, and inducers. Drug Metab Rev 2002; 34: 47-54.
    • (2002) Drug Metab Rev , vol.34 , pp. 47-54
    • Kim, R.B.1
  • 46
    • 0029028792 scopus 로고
    • Overlapping substrate specifi cities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implication for drug delivery and activity in cancer chemotherapy
    • Wacher VJ, Wu CY, Benet LZ. Overlapping substrate specifi cities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implication for drug delivery and activity in cancer chemotherapy. Mol Carcinog 1995; 13: 129-34.
    • (1995) Mol Carcinog , vol.13 , pp. 129-134
    • Wacher, V.J.1    Wu, C.Y.2    Benet, L.Z.3
  • 47
    • 0037303706 scopus 로고    scopus 로고
    • A nuclear receptor-mediated xenobiotic response and its implication in drug metabolism and host protection
    • Sonoda J, Rosenfeld JM, Xu L, Evans RM, Xie W. A nuclear receptor-mediated xenobiotic response and its implication in drug metabolism and host protection. Curr Drug Metab 2003; 4: 59-72.
    • (2003) Curr Drug Metab , vol.4 , pp. 59-72
    • Sonoda, J.1    Rosenfeld, J.M.2    Xu, L.3    Evans, R.M.4    Xie, W.5
  • 48
    • 0035805536 scopus 로고    scopus 로고
    • Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin
    • Geick A, Eichelbaum M, Burk O. Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin. J Biol Chem 2001; 276: 14581-7.
    • (2001) J Biol Chem , vol.276 , pp. 14581-7
    • Geick, A.1    Eichelbaum, M.2    Burk, O.3
  • 49
    • 6344250770 scopus 로고    scopus 로고
    • 57 Varieties: the human cytochromes P450
    • Lewis DF. 57 Varieties: the human cytochromes P450. Pharmacogenomics 2004; 5: 305-18.
    • (2004) Pharmacogenomics , vol.5 , pp. 305-318
    • Lewis, D.F.1
  • 50
    • 13944274619 scopus 로고    scopus 로고
    • Clinical and toxicological relevance of CYP2C9: drug-drug interactions and pharmacogenetics
    • Rettie AE, Jones JP. Clinical and toxicological relevance of CYP2C9: drug-drug interactions and pharmacogenetics. Annu Rev Pharmacol Toxicol 2005; 45: 477-94.
    • (2005) Annu Rev Pharmacol Toxicol , vol.45 , pp. 477-494
    • Rettie, A.E.1    Jones, J.P.2
  • 51
    • 0032613125 scopus 로고    scopus 로고
    • Cytochrome P450 CYP2D6
    • Wolf CR, Smith G. Cytochrome P450 CYP2D6. IARC Sci Publ 1999; 148: 209-29.
    • (1999) IARC Sci Publ , vol.148 , pp. 209-229
    • Wolf, C.R.1    Smith, G.2
  • 52
    • 10644271665 scopus 로고    scopus 로고
    • Induction of cytochromes P450
    • Dickins M. Induction of cytochromes P450. Curr Top Med Chem 2004; 4: 1745-66.
    • (2004) Curr Top Med Chem , vol.4 , pp. 1745-1766
    • Dickins, M.1
  • 53
    • 0037181419 scopus 로고    scopus 로고
    • Tacrolimus-induced nephrotoxicity unmasked by induction of the CYP3A4 system with St John's wort
    • Bolley R, Zulke C, Kammerl M, Fischereder M, Kramer BK. Tacrolimus-induced nephrotoxicity unmasked by induction of the CYP3A4 system with St John's wort. Transplantation 2002; 73: 1009.
    • (2002) Transplantation , vol.73 , pp. 1009
    • Bolley, R.1    Zulke, C.2    Kammerl, M.3    Fischereder, M.4    Kramer, B.K.5
  • 54
    • 0042950000 scopus 로고    scopus 로고
    • Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects
    • Dresser GK, Schwarz UI, Wilkinson GR, Kim RB. Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects. Clin Pharmacol Ther 2003; 73: 41-50.
    • (2003) Clin Pharmacol Ther , vol.73 , pp. 41-50
    • Dresser, G.K.1    Schwarz, U.I.2    Wilkinson, G.R.3    Kim, R.B.4
  • 56
    • 0034695608 scopus 로고    scopus 로고
    • Effect of John's wort (Hypericum perforatum) on cytochrome P-450 2D6 and 3A4 activity in healthy volunteers
    • Markowitz JS, DeVane CL, Boulton DW, Carson SW, Nahas Z, Risch SC. Effect of St. John's wort (Hypericum perforatum) on cytochrome P-450 2D6 and 3A4 activity in healthy volunteers. Life Sci 2000; 66: PL133-9.
    • (2000) Life Sci , vol.66
    • Markowitz, J.S.1    DeVane, C.L.2    Boulton, D.W.3    Carson, S.W.4    Nahas, Z.5    Risch, S.C.6
  • 58
    • 30844472028 scopus 로고    scopus 로고
    • The extent of induction of CYP3A by St. John's wort varies among products and is linked to hyperforin dose
    • Mueller SC, Majcher-Peszynska J, Uehleke B, et al. The extent of induction of CYP3A by St. John's wort varies among products and is linked to hyperforin dose. Eur J Clin Pharmacol 2006; 62: 29-36.
    • (2006) Eur J Clin Pharmacol , vol.62 , pp. 29-36
    • Mueller, S.C.1    Majcher-Peszynska, J.2    Uehleke, B.3
  • 59
    • 33644891064 scopus 로고    scopus 로고
    • MDR-and CYP3A4-mediated drug-herbal interactions
    • Pal D, Mitra AK. MDR-and CYP3A4-mediated drug-herbal interactions. Life Sci 2006; 78: 2131-45.
    • (2006) Life Sci , vol.78 , pp. 2131-2145
    • Pal, D.1    Mitra, A.K.2
  • 61
    • 12144289727 scopus 로고    scopus 로고
    • St John's wort induces both cytochrome P450 3A4-catalyzed sulfoxidation and 2C19-dependent hydroxylation of omeprazole
    • Wang LS, Zhou G, Zhu B, et al. St John's wort induces both cytochrome P450 3A4-catalyzed sulfoxidation and 2C19-dependent hydroxylation of omeprazole. Clin Pharmacol Ther 2004; 75: 191-7.
    • (2004) Clin Pharmacol Ther , vol.75 , pp. 191-197
    • Wang, L.S.1    Zhou, G.2    Zhu, B.3
  • 62
    • 1942423663 scopus 로고    scopus 로고
    • Effect of St John's wort on the activities of CYP1A2, CYP3A4, CYP2D6, N-acetyltransferase 2, and xanthine oxidase in healthy males and females
    • Wenk M, Todesco L, Krahenbuhl S. Effect of St John's wort on the activities of CYP1A2, CYP3A4, CYP2D6, N-acetyltransferase 2, and xanthine oxidase in healthy males and females. Br J Clin Pharmacol 2004; 57: 495-9.
    • (2004) Br J Clin Pharmacol , vol.57 , pp. 495-499
    • Wenk, M.1    Todesco, L.2    Krahenbuhl, S.3
  • 63
    • 0034790753 scopus 로고    scopus 로고
    • St. John's wort: effect on CYP2D6 activity using dextromethorphan-dextrorphan ratios
    • Roby CA, Dryer DA, Burstein AH. St. John's wort: effect on CYP2D6 activity using dextromethorphan-dextrorphan ratios. J Clin Psychopharmacol 2001; 21: 530-2.
    • (2001) J Clin Psychopharmacol , vol.21 , pp. 530-532
    • Roby, C.A.1    Dryer, D.A.2    Burstein, A.H.3
  • 64
    • 0037383772 scopus 로고    scopus 로고
    • Impact of St John's wort treatment on the pharmacokinetics of tacrolimus and mycophenolic acid in renal transplant patients
    • Mai I, Stormer E, Bauer S, Kruger H, Budde K, Roots I. Impact of St John's wort treatment on the pharmacokinetics of tacrolimus and mycophenolic acid in renal transplant patients. Nephrol Dial Transplant 2003; 18: 819-22.
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 819-822
    • Mai, I.1    Stormer, E.2    Bauer, S.3    Kruger, H.4    Budde, K.5    Roots, I.6
  • 66
    • 11144355476 scopus 로고    scopus 로고
    • Induction and inhibition of cytochromes P450 by the St. John's wort constituent hyperforin in human hepatocyte cultures
    • Komoroski BJ, Zhang S, Cai H, et al. Induction and inhibition of cytochromes P450 by the St. John's wort constituent hyperforin in human hepatocyte cultures. Drug Metab Dispos 2004; 32: 512-8.
    • (2004) Drug Metab Dispos , vol.32 , pp. 512-518
    • Komoroski, B.J.1    Zhang, S.2    Cai, H.3
  • 68
    • 2442654207 scopus 로고    scopus 로고
    • The infl uence of St John's wort on CYP2C19 activity with respect to genotype
    • Wang LS, Zhu B, Abd El-Aty AM, et al. The infl uence of St John's wort on CYP2C19 activity with respect to genotype. J Clin Pharmacol 2004; 44: 577-81.
    • (2004) J Clin Pharmacol , vol.44 , pp. 577-581
    • Wang, L.S.1    Zhu, B.2    Abd El-Aty, A.M.3
  • 70
    • 67651208865 scopus 로고    scopus 로고
    • Trade herbal products and induction of CYP2C19 and CYP2E1 in cultured human hepatocytes
    • Hellum BH, Hu Z, Nilsen OG. Trade herbal products and induction of CYP2C19 and CYP2E1 in cultured human hepatocytes. Basic Clin Pharmacol Toxicol 2009; 105: 58-63.
    • (2009) Basic Clin Pharmacol Toxicol , vol.105 , pp. 58-63
    • Hellum, B.H.1    Hu, Z.2    Nilsen, O.G.3
  • 77
    • 0032498303 scopus 로고    scopus 로고
    • An orphan nuclear receptor activated by pregnanes defi nes a novel steroid signaling pathway
    • Kliewer SA, Moore JT, Wade L, et al. An orphan nuclear receptor activated by pregnanes defi nes a novel steroid signaling pathway. Cell 1998; 92: 73-82.
    • (1998) Cell , vol.92 , pp. 73-82
    • Kliewer, S.A.1    Moore, J.T.2    Wade, L.3
  • 78
    • 0032169485 scopus 로고    scopus 로고
    • The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions
    • Lehmann JM, McKee DD, Watson MA, Willson TM, Moore JT, Kliewer SA. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. J Clin Invest 1998; 102: 1016-23.
    • (1998) J Clin Invest , vol.102 , pp. 1016-1023
    • Lehmann, J.M.1    McKee, D.D.2    Watson, M.A.3    Willson, T.M.4    Moore, J.T.5    Kliewer, S.A.6
  • 79
    • 0029440036 scopus 로고
    • Transcription factors 3: nuclear receptors
    • Gronemeyer H, Laudet V. Transcription factors 3: nuclear receptors. Protein Profi le 1995; 2: 1173-308.
    • (1995) Protein Profi le , vol.2 , pp. 1173-1308
    • Gronemeyer, H.1    Laudet, V.2
  • 80
    • 0038000046 scopus 로고    scopus 로고
    • The nuclear pregnane X receptor regulates xenobiotic detoxifi cation
    • Kliewer SA. The nuclear pregnane X receptor regulates xenobiotic detoxifi cation. J Nutr 2003; 133: 2444S-7S.
    • (2003) J Nutr , vol.133
    • Kliewer, S.A.1
  • 81
    • 0036799870 scopus 로고    scopus 로고
    • The nuclear pregnane X receptor regulates xenobiotic detoxifi cation
    • Kliewer SA, Goodwin B, Willson TM. The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism. Endocr Rev 2002; 23: 687-702.
    • (2003) J Nutr , vol.133 , pp. 687-702
    • Kliewer, S.A.1
  • 86
    • 57849117383 scopus 로고    scopus 로고
    • No clinically relevant CYP3A induction after St. John's wort with low hyperforin content in healthy volunteers
    • Mueller SC, Majcher-Peszynska J, Mundkowski RG, et al. No clinically relevant CYP3A induction after St. John's wort with low hyperforin content in healthy volunteers. Eur J Clin Pharmacol 2009; 65: 81-87.
    • (2009) Eur J Clin Pharmacol , vol.65 , pp. 81-87
    • Mueller, S.C.1    Majcher-Peszynska, J.2    Mundkowski, R.G.3
  • 88
    • 60549099725 scopus 로고    scopus 로고
    • St John's wort extract (Ze 117) does not alter the pharmacokinetics of a low-dose oral contraceptive
    • Will-Shahab L, Bauer S, Kunter U, Roots I, Brattstrom A. St John's wort extract (Ze 117) does not alter the pharmacokinetics of a low-dose oral contraceptive. Eur J Clin Pharmacol 2009; 65: 287-94.
    • (2009) Eur J Clin Pharmacol , vol.65 , pp. 287-294
    • Will-Shahab, L.1    Bauer, S.2    Kunter, U.3    Roots, I.4    Brattstrom, A.5
  • 89
    • 22444444798 scopus 로고    scopus 로고
    • Evolution of the pregnane X receptor: adaptation to cross-species differences in biliary bile salts
    • Krasowski MD, Yasuda K, Hagey LR, Schuetz EG. Evolution of the pregnane X receptor: adaptation to cross-species differences in biliary bile salts. Mol Endocrinol 2005; 19: 1720-39.
    • (2005) Mol Endocrinol , vol.19 , pp. 1720-1739
    • Krasowski, M.D.1    Yasuda, K.2    Hagey, L.R.3    Schuetz, E.G.4
  • 90
    • 27344451707 scopus 로고    scopus 로고
    • Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors)
    • Krasowski MD, Yasuda K, Hagey LR, Schuetz EG. Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors). Nucl Recept 2005; 3: 2.
    • (2005) Nucl Recept , vol.3 , pp. 2
    • Krasowski, M.D.1    Yasuda, K.2    Hagey, L.R.3    Schuetz, E.G.4
  • 91
    • 0036256351 scopus 로고    scopus 로고
    • Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) defi ne three pharmacologically distinct classes of nuclear receptors
    • Moore LB, Maglich JM, McKee DD, Wisely B, Willson TM, Kliewer SA, Lambert MH, Moore JT. Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) defi ne three pharmacologically distinct classes of nuclear receptors. Mol Endocrinol 2002; 16: 977-86.
    • (2002) Mol Endocrinol , vol.16 , pp. 977-986
    • Moore, L.B.1    Maglich, J.M.2    McKee, D.D.3    Wisely, B.4    Willson, T.M.5    Kliewer, S.A.6    Lambert, M.H.7    Moore, J.T.8
  • 93
    • 33646513294 scopus 로고    scopus 로고
    • Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds
    • Reschly EJ, Krasowski MD. Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds. Curr Drug Metab 2006; 7: 349-65.
    • (2006) Curr Drug Metab , vol.7 , pp. 349-365
    • Reschly, E.J.1    Krasowski, M.D.2
  • 98
    • 0014209615 scopus 로고
    • Effect of phenobarbital on jaundice
    • Schwartz GR. Effect of phenobarbital on jaundice. N Engl J Med 1967; 277: 375.
    • (1967) N Engl J Med , vol.277 , pp. 375
    • Schwartz, G.R.1
  • 99
    • 0014031478 scopus 로고
    • Enhancement of glucuronide-conjugating capacity in a hyperbilirubinemic infant due to apparent enzyme induction by phenobarbital
    • Yaffe SJ, Levy G, Matsuzawa T, Baliah T. Enhancement of glucuronide-conjugating capacity in a hyperbilirubinemic infant due to apparent enzyme induction by phenobarbital. N Engl J Med 1966; 275: 1461-6.
    • (1966) N Engl J Med , vol.275 , pp. 1461-1466
    • Yaffe, S.J.1    Levy, G.2    Matsuzawa, T.3    Baliah, T.4
  • 100
    • 0014214809 scopus 로고
    • Treatment of chronic intrahepatic cholestasis with phenobarbitone
    • Thompson RP, Williams R. Treatment of chronic intrahepatic cholestasis with phenobarbitone. Lancet 1967; 2: 646-8.
    • (1967) Lancet , vol.2 , pp. 646-648
    • Thompson, R.P.1    Williams, R.2
  • 101
    • 34247473771 scopus 로고    scopus 로고
    • Phenobarbital suppresses vitamin D3 25-hydroxylase expression: a potential new mechanism for drug-induced osteomalacia
    • Hosseinpour F, Ellfolk M, Norlin M, Wikvall K. Phenobarbital suppresses vitamin D3 25-hydroxylase expression: a potential new mechanism for drug-induced osteomalacia. Biochem Biophys Res Commun 2007; 357: 603-7.
    • (2007) Biochem Biophys Res Commun , vol.357 , pp. 603-607
    • Hosseinpour, F.1    Ellfolk, M.2    Norlin, M.3    Wikvall, K.4
  • 102
    • 85047693782 scopus 로고    scopus 로고
    • Possible involvement of pregnane X receptor-enhanced CYP24 expression in drug-induced osteomalacia
    • Pascussi JM, Robert A, Nguyen M, et al. Possible involvement of pregnane X receptor-enhanced CYP24 expression in drug-induced osteomalacia. J Clin Invest 2005; 115: 177-86.
    • (2005) J Clin Invest , vol.115 , pp. 177-186
    • Pascussi, J.M.1    Robert, A.2    Nguyen, M.3
  • 104
    • 33846054889 scopus 로고    scopus 로고
    • Drug-induced musculoskeletal disorders
    • Bannwarth B. Drug-induced musculoskeletal disorders. Drug Saf 2007; 30: 27-46.
    • (2007) Drug Saf , vol.30 , pp. 27-46
    • Bannwarth, B.1
  • 105
    • 0036936388 scopus 로고    scopus 로고
    • Drug-induced metabolic bone disorders
    • Lawson J. Drug-induced metabolic bone disorders. Semin Musculoskelet Radiol 2002; 6: 285-297.
    • (2002) Semin Musculoskelet Radiol , vol.6 , pp. 285-297
    • Lawson, J.1
  • 106
    • 0034840412 scopus 로고    scopus 로고
    • Adverse effects of antiepileptic drugs on bone structure: epidemiology, mechanisms and therapeutic implications
    • Pack AM, Morrell MJ. Adverse effects of antiepileptic drugs on bone structure: epidemiology, mechanisms and therapeutic implications. CNS Drugs 2001; 15: 633-42.
    • (2001) CNS Drugs , vol.15 , pp. 633-642
    • Pack, A.M.1    Morrell, M.J.2
  • 107
    • 33845970888 scopus 로고    scopus 로고
    • Activation of pregnane X receptor disrupts glucocorticoid and mineralocorticoid homeostasis
    • Zhai Y, Pai HV, Zhou J, Amico JA, Vollmer RR, Xie W. Activation of pregnane X receptor disrupts glucocorticoid and mineralocorticoid homeostasis. Mol Endocrinol 2007; 21: 138-47.
    • (2007) Mol Endocrinol , vol.21 , pp. 138-147
    • Zhai, Y.1    Pai, H.V.2    Zhou, J.3    Amico, J.A.4    Vollmer, R.R.5    Xie, W.6
  • 108
    • 61549104490 scopus 로고    scopus 로고
    • PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics
    • Zhang B, Xie W, Krasowski MD. PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics. Pharmacogenomics 2008; 9: 1695-709.
    • (2008) Pharmacogenomics , vol.9 , pp. 1695-1709
    • Zhang, B.1    Xie, W.2    Krasowski, M.D.3
  • 109
    • 66549096969 scopus 로고    scopus 로고
    • Associations of herbal and specialty supplements with lung and colorectal cancer risk in the VITamins and Lifestyle study
    • Satia JA, Littman A, Slatore CG, Galanko JA, White E. Associations of herbal and specialty supplements with lung and colorectal cancer risk in the VITamins and Lifestyle study. Cancer Epidemiol Biomarkers Prev 2009; 18: 1419-28.
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , pp. 1419-1428
    • Satia, J.A.1    Littman, A.2    Slatore, C.G.3    Galanko, J.A.4    White, E.5
  • 111
    • 10744232730 scopus 로고    scopus 로고
    • Alterations in cyclosporin A pharmacokinetics and metabolism during treatment with St John's wort in renal transplant patients
    • Bauer S, Stormer E, Johne A, Kruger H, Budde K, Neumayer HH, Roots I, Mai I. Alterations in cyclosporin A pharmacokinetics and metabolism during treatment with St John's wort in renal transplant patients. Br J Clin Pharmacol 2003; 55: 203-11.
    • (2003) Br J Clin Pharmacol , vol.55 , pp. 203-211
    • Bauer, S.1    Stormer, E.2    Johne, A.3    Kruger, H.4    Budde, K.5    Neumayer, H.H.6    Roots, I.7    Mai, I.8
  • 113
    • 0344081240 scopus 로고    scopus 로고
    • Interaction of St John's wort with low-dose oral contraceptive therapy: a randomized controlled trial
    • Pfrunder A, Schiesser M, Gerber S, Haschke M, Bitzer J, Drewe J. Interaction of St John's wort with low-dose oral contraceptive therapy: a randomized controlled trial. Br J Clin Pharmacol 2003; 56: 683-90.
    • (2003) Br J Clin Pharmacol , vol.56 , pp. 683-690
    • Pfrunder, A.1    Schiesser, M.2    Gerber, S.3    Haschke, M.4    Bitzer, J.5    Drewe, J.6
  • 114
    • 0037241016 scopus 로고    scopus 로고
    • Unwanted pregnancy on self-medication with St John's wort despite hormonal contraception
    • Schwarz UI, Büschel B, Kirch W. Unwanted pregnancy on self-medication with St John's wort despite hormonal contraception. Br J Clin Pharmacol 2003; 55: 112-3.
    • (2003) Br J Clin Pharmacol , vol.55 , pp. 112-113
    • Schwarz, U.I.1    Büschel, B.2    Kirch, W.3
  • 116
    • 33750316890 scopus 로고    scopus 로고
    • Interactions between natural health products and antiretroviral drugs: pharmacokinetic and pharmacodynamic effects
    • Lee LS, Andrade AS, Flexner C. Interactions between natural health products and antiretroviral drugs: pharmacokinetic and pharmacodynamic effects. Clin Infect Dis 2006; 43: 1052-9.
    • (2006) Clin Infect Dis , vol.43 , pp. 1052-1059
    • Lee, L.S.1    Andrade, A.S.2    Flexner, C.3
  • 117
    • 5444251235 scopus 로고    scopus 로고
    • In vitro interaction of the HIV protease inhibitor ritonavir with herbal constituents: changes in P-gp and CYP3A4 activity
    • Patel J, Buddha B, Dey S, Pal D, Mitra AK. In vitro interaction of the HIV protease inhibitor ritonavir with herbal constituents: changes in P-gp and CYP3A4 activity. Am J Ther 2004; 11: 262-77.
    • (2004) Am J Ther , vol.11 , pp. 262-277
    • Patel, J.1    Buddha, B.2    Dey, S.3    Pal, D.4    Mitra, A.K.5
  • 121
    • 34548609183 scopus 로고    scopus 로고
    • Effects of treatment with a commercially available St John's wort product (Movina) on cholesterol levels in patients with hypercholesterolemia treated with simvastatin
    • Eggertsen R, Andreasson A, Andren L. Effects of treatment with a commercially available St John's wort product (Movina) on cholesterol levels in patients with hypercholesterolemia treated with simvastatin. Scand J Prim Health Care 2007; 25: 154-9.
    • (2007) Scand J Prim Health Care , vol.25 , pp. 154-159
    • Eggertsen, R.1    Andreasson, A.2    Andren, L.3
  • 122
    • 0035652201 scopus 로고    scopus 로고
    • Different effects of St John's wort on the pharmacokinetics of simvastatin and pravastatin
    • Sugimoto K, Ohmori M, Tsuruoka S, et al. Different effects of St John's wort on the pharmacokinetics of simvastatin and pravastatin. Clin Pharmacol Ther 2001; 70: 518-24.
    • (2001) Clin Pharmacol Ther , vol.70 , pp. 518-524
    • Sugimoto, K.1    Ohmori, M.2    Tsuruoka, S.3
  • 123
    • 0346994708 scopus 로고    scopus 로고
    • Effects of St. John's wort (Hypericum perforatum) on tacrolimus pharmacokinetics in healthy volunteers
    • Hebert MF, Park JM, Chen YL, Akhtar S, Larson AM. Effects of St. John's wort (Hypericum perforatum) on tacrolimus pharmacokinetics in healthy volunteers. J Clin Pharmacol 2004; 44: 89-94.
    • (2004) J Clin Pharmacol , vol.44 , pp. 89-94
    • Hebert, M.F.1    Park, J.M.2    Chen, Y.L.3    Akhtar, S.4    Larson, A.M.5
  • 124
    • 0346364812 scopus 로고    scopus 로고
    • Effect of St. John's wort on the pharmacokinetics of theophylline in healthy volunteers
    • Morimoto T, Kotegawa T, Tsutsumi K, Ohtani Y, Imai H, Nakano S. Effect of St. John's wort on the pharmacokinetics of theophylline in healthy volunteers. J Clin Pharmacol 2004; 44: 95-101.
    • (2004) J Clin Pharmacol , vol.44 , pp. 95-101
    • Morimoto, T.1    Kotegawa, T.2    Tsutsumi, K.3    Ohtani, Y.4    Imai, H.5    Nakano, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.