Drug-induced musculoskeletal disorders

Drug Safety

Volumn 30, Issue 1, 2007, Pages 27-46

  Bannwarth, Bernard ^a,b  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b HÔPITAL PELLEGRIN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ANTICONVULSIVE AGENT; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; ANTIULCER AGENT; BISPHOSPHONIC ACID DERIVATIVE; CHLOROQUINE; CIPROFLOXACIN; COLCHICINE; CORTICOSTEROID; CYCLOSPORIN A; DICLOFENAC; DIPHTHERIA TETANUS VACCINE; DIURETIC AGENT; HEPARIN; HEPATITIS B VACCINE; HISTAMINE H2 RECEPTOR ANTAGONIST; HYALURONIC ACID; LOW MOLECULAR WEIGHT HEPARIN; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT; OMEPRAZOLE; PREDNISONE; PYRAZINAMIDE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SALICYLIC ACID; TACROLIMUS; TRIAMCINOLONE ACETONIDE; UNINDEXED DRUG; ZIDOVUDINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTHRALGIA; ARTHRITIS; ARTHROPATHY; BACTERIAL ARTHRITIS; BONE DISEASE; BONE NECROSIS; CHONDROPATHY; CLINICAL TRIAL; CONNECTIVE TISSUE DISEASE; CONTROLLED CLINICAL TRIAL; CREATINE KINASE BLOOD LEVEL; DERMATOMYOSITIS; DOSE RESPONSE; DRUG INDUCED DISEASE; DRUG MEGADOSE; DRUG POTENTIATION; DRUG WITHDRAWAL; ENTHESOPATHY; FROZEN SHOULDER; GOUT; GRAFT REJECTION; HIP OSTEOARTHRITIS; HUMAN; HYPERURICEMIA; INFECTION; INJECTION SITE INFLAMMATION; INJECTION SITE REACTION; JOINT INJURY; KNEE OSTEOARTHRITIS; LOW DRUG DOSE; MITOCHONDRIAL MYOPATHY; MONARTHRITIS; MULTIPLE CYCLE TREATMENT; MUSCULOSKELETAL DISEASE; MYOPATHY; NEUROMUSCULAR DISEASE; NEUROPATHIC JOINT DISEASE; NONHUMAN; OSTEOARTHRITIS; OSTEOMALACIA; OSTEOPOROSIS; POLYARTHRITIS; POLYMYOSITIS; POLYNEUROPATHY; PRIORITY JOURNAL; PSEUDOGOUT; RANDOMIZED CONTROLLED TRIAL; REVIEW; RHABDOMYOLYSIS; RHEUMATIC POLYMYALGIA; RHEUMATOID ARTHRITIS; RICKETS; SCLERODERMA; SIDE EFFECT; SYNOVITIS; SYSTEMIC LUPUS ERYTHEMATOSUS; TENDINITIS; TUBERCULOSIS; VASCULITIS; VITAMIN D DEFICIENCY;

EID: 33846054889     PISSN: 01145916     EISSN: None     Source Type: Journal    
DOI: 10.2165/00002018-200730010-00004     Document Type: Review

References (136)

1. Bannwarth B. Drug-induced rheumatic disorders. Rev Rhum Engl Ed 1996; 63: 639-47
2. Cohen MG, Prowse MV. Drug-induced rheumatic syndromes. Diagnosis, clinical features and management. Med Toxicol Adverse Drug Exp 1989; 4: 199-218
3. Vergne P, Bertin P, Bonnet C, et al. Drug-induced rheumatic disorders: incidence, prevention and management. Drug Saf 2000 Oct; 23 (4): 279-93
4. Bannwarth B. Drug-induced myopathies. Expert Opin Drug Saf 2002; 1: 65-70
5. Stahlmann R, Förster C, Van Sickle D. Quinolones in children. Are concerns over arthropathy justified? Drug Saf 1993; 9: 397-403
6. Hampel B, Hullmann R, Schmidt H. Ciprofloxacin in pediatrics: worldwide clinical experience based on compassionate use. Safety report. Pediatr Infect Dis J 1997 Jan; 16 (1): 127-9
7. Camp KA, Miyagi SL, Schroeder DJ. Potential quinolone-induced cartilage toxicity in children. Ann Pharmacother 1994; 28: 336-8
8. Doherty M, Jones A. Indomethacin hastens large joint osteoarthritis in humans. How strong is the evidence? J Rheumatol 1995; 22: 2013-6
9. Reijman M, Bierma-Zeinstra SMA, Pols HAP, et al. Is there an association between the use of different types of nonsteroidal antiinflammatory drugs and radiologic progression of osteoarthritis? The Rotterdam study. Arthritis Rheum 2005 Oct; 52 (10): 3137-42
10. Hunter JA, Blyth TH. A risk-benefit assessment of intra-articular corticosteroids in rheumatic disorders. Drug Saf 1999 Nov; 21 (5): 353-65
11. Roberts WN, Babcock EA, Breitbach SA, et al. Corticosteroid injection in rheumatoid arthritis does not increase rate of total joint arthroplasty. J Rheumatol 1999; 23: 1001-4
12. Raynaud JP, Buckland-Wright C, Ward R, et al. Safety and efficacy of long-term intra-articular steroid injections in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2003 Feb; 48 (2): 370-7
13. Mikuls TR, Farrar JT, Bilker WB, et al. Gout epidemiology: results from the UK general practice database, 1990-1999. Ann Rheum Dis 2005; 64: 267-72
14. Terkeltaub RA. Gout. N Engl J Med 2003; 349: 1647-55
15. Schlesinger N. Management of acute and chronic gouty arthritis. Present state-of-the art. Drugs 2004; 64: 2399-416
16. Borstad GC, Bryant LR, Abel MP, et al. Colchicine for prophylaxis of acute flares when initiating allopurinol for chronic gouty arthritis. J Rheumatol 2004 Dec; 31 (12): 2429-32
17. Gerster JC, Dudler M, Halkic N, et al. Gout in liver transplant patients receiving tacrolimus. Ann Rheum Dis 2004; 63: 894-5
18. Abbott KC, Kimmel PL, Dharnidharka V, et al. New-onset gout after kidney transplantation: incidence, risk factors and implications. Transplantation 2005; 80: 1383-91
19. Mazzali M. Uric acid and transplantations. Semin Nephrol 2005 Jan; 25 (1): 50-5
20. Meier CR, Jick H. Omeprazole, other anticulcer drugs and newly diagnosed gout. Br J Clin Pharmacol 1997; 44: 175-8
21. Young-Min SA, Herbert L, Dick M, et al. Weekly alendronate-induced acute pseudogout. Rheumatology 2005; 44: 131-2
22. Arrich J, Piribauer F, Mad P, et al. Intra-articular hyaluronic acid for the treatment of osteoarthritis of the knee: systematic review and meta-analysis. CMAJ 2005; 172: 1039-43
23. Adams ME, Lussier AJ, Peyron JG. A risk-benefit assessment of injections of hyaluronan and its derivatives in the treatment of osteoarthritis of the knee. Drug Saf 2000 Aug; 23 (2): 115-30
24. Pullman-Mooar S, Mooar P, Sieck M, et al. Are there distinctive inflammatory flares after hylan G-F 20 intraarticular injections? J Rheumatol 2002; 29: 2611-4
25. Brandt KD, Smith GN, Simon LS. Intraarticular injection of hyaluronan as treatment for knee osteoarthritis. Arthritis Rheum 2000 Jun; 43 (6): 1132-203
26. Leopold SS, Warme WJ, Pettis PD, et al. Increased frequency of acute local reaction to intra-articular Hylan GF-20 (Synvisc) in patients receiving more than one course of treatment. J Bone Joint Surg Am 2002 Sept; 84A (9): 1619-23
27. Harrison BJ, Thomson W, Pepper L, et al. Patients who develop inflammatory polyarthitis (IP) after immunization are clinically indistinguishable from other patients with IP. Br J Rheumatol 1997; 36: 366-9
28. Symmons DPM, Chakravarty K. Can immunisation trigger rheumatoid arthritis? Ann Rheum Dis 1993; 5: 843-4
29. Geier DA, Geier MR. A case-control study of serious autoimmune adverse events following hepatitis B immunization. Autoimmunity 2005 Jun; 28 (4): 295-301
30. Sibilia J, Maillefert JF. Vaccination and rheumatoid arthritis. Ann Rheum Dis 2002; 61: 575-6
31. Geier MR, Geier DA, Zahalsky AC. A review of hepatitis B vaccination. Expert Opin Drug Saf 2003 Mar; 2 (2): 113-20
32. Elkayam O, Yaron M, Caspi D. Safety and efficacy of vaccination against hepatitis B in patients with rheumatoid arthritis. Ann Rheum Dis 2002; 61: 623-5
33. Pope JE, Stevens A, Howson W, et al. The development of rheumatoid arthritis after recombination hepatitis B vaccination. J Rheumatol 1998; 25: 1687-93
34. Tingle AJ, Mitchell LA, Grace M, et al. Randomised double-blind placebo controlled study on adverse effects of rubella immunisation in seronegative women. Lancet 1997; 349: 1277-81
35. Geier DA, Geier MR. A one year followup of chronic arthritis following rubella and hepatitis B vaccination upon analysis of the Vaccine Adverse Events Reporting System (VAERS) database. Clin Exp Rheumatol 2002; 20: 767-71
36. Ray P, Black S, Shinefield H, et al. Risk of chronic arthropathy among women after rubella vaccination. JAMA 1997; 278: 551-6
37. Tingle AJ, Allen M, Petty RE, et al. Rubella-associated arthritis. I. Comparative study of joint manifestations associated with natural rubella infection and RA 27/3 rubella immunisation. Ann Rheum Dis 1986; 45: 110-4
38. Slater PE. Chronic arthropathy after rubella vaccination in women. False alarm? JAMA 1997; 278: 594-5
39. Buchs N, Chevrel G, Miossec P. Bacillus Calmette-Guérin induced aseptic arthritis: an experimental model of reactive arthritis. J Rheumatol 1998; 25: 1662-5
40. Miossec P. Cytokine-induced autoimmune disorders. Drug Saf 1997 Aug; 17 (2): 93-104
41. Ioannou Y, Isenberg DA. Current evidence for the induction of autoimmune rheumatic manifestations by cytokine therapy. Arthritis Rheum 2000 Jul; 43 (7): 1431-42
42. Nesher G, Ruchlemer R. Alpha-interferon-induced arthritis: clinical presentation, treatment, and prevention. Semin Arthritis Rheum 1998; 27: 360-5
43. Nissen MJ, Fontanges E, Allam Y, et al. Rheumatological manifestations of hepatitis C: incidence in a rheumatology and non-rheumatology setting and the effect of methotrexate and interferon. Rheumatology 2005; 44: 1016-20
44. Tsukadaira A, Takashi S, Kubo K, et al. Repeated arthralgia associated with granulocyte colony stimulating factor administration. Ann Rheum Dis 2002; 61: 850-1
45. ten Holder SM, Joy MS, Falk RJ. Cutaneous and systemic manifestations of drug-induced vasculitis. Ann Pharmacother 2002; 36: 130-47
46. Cohen MG, Kevat S, Prowse MV, et al. Two distinct quinidine-induced rheumatic syndromes. Ann Intern Med 1988; 108: 369-71
47. Dakik HA, Salti I, Haidar R, et al. Ticlopidine associated with acute arthritis. BMJ 2002; 324: 27
48. Boulman N, Rozenbaum M, Slobodin G, et al. Acute polyarthritis associated with clopidogrel treatment. Isr Med Assoc J 2005; 7: 670-1
49. Jolliet P, Veyrac G, Bourin M. First report of mirtazapine-induced arthralgia. Eur Psychiatry 2001 Dec; 16 (8): 503-5
50. Ornetti P, Disson-Dautriche A, Muller G, et al. Joint symptoms in patients on bupropion therapy. Joint Bone Spine 2004; 71: 583-5
51. Gamarra RM, McGraw SD, Drelichman VS, et al. Serum sickness-like reactions in patients receiving intravenous infliximab. J Emerg Med 2006; 30: 41-4
52. Adami S, Zamberlan N. Adverse effects of bisphosphonates. A comparative review. Drug Saf 1996 Mar; 14 (3): 158-70
53. Gerster JC, Nicole F. Acute polyarthritis related to once-weekly alendronate in a women with osteoporosis. J Rheumatol 2004; 31: 829-30
54. Wysowski DK, Chang JT. Alendronate and risedronate: reports of severe bone, joint, and muscle pain. Arch Intern Med 2005; 165: 346-7
55. Berkovitch M, Laxer RM, Inman R, et al. Arthropathy in thalassaemia patients receiving deferiprone. Lancet 1994; 343: 1471-2
56. Kontoghiorghes GJ, Neocleous K, Kolnagou A. Benefits and risks of deferiprone in iron overload in thalassaemia and other conditions. Drug Saf 2003; 26: 553-84
57. Price EJ, Venables PJW. Drug-induced lupus. Drug Saf 1995; 12: 283-90
58. Sarzi-Puttini P, Atzeni F, Capsoni F, et al. Drug-induced lupus erythematosus. Autoimmunity 2005 Nov; 38 (7): 507-18
59. Brogan BL, Olsen NJ. Drug-induced rheumatic syndromes. Curr Opin Rheumatol 2003; 15: 76-80
60. Khanna D, McMahon M, Furst DE. Safety of tumour necrosis factor-α antagonists. Drug Saf 2004; 27: 307-24
61. Day R. Adverse reactions to TNF-α inhibitors in rheumatoid arthritis. Lancet 2002; 359: 540-1
62. Hyrich KL, Silman AJ, Watson KD, et al. Anti-tumour necrosis factor α therapy in rheumatoid arthritis: an update on safety. Ann Rheum Dis 2004; 63: 1538-43
63. De Bandt M, Sibilia J, Le Loët X, et al. Systemic lupus erythematosus induced by anti-tumour necrosis factor alpha therapy: a French national survey. Arthritis Res Ther 2005; 7: R545-51
64. Haustein UF, Haupt B. Drug-induced scleroderma and sclerodermiform conditions. Clin Dermatol 1998; 16: 353-66
65. Khaliq Y, Zhanel GG. Fluoroquinolone-associated tendinopathy: a critical review of the literature. Clin Infect Dis 2003; 36: 1404-10
66. Van der Linden PD, Sturkenboom MCJM, Herings RMC, et al. Fluoroquinolone and risk of Achilles tendon disorders: case-control study. BMJ 2002; 324: 1306-7
67. Van der Linden PD, Sturkenboom MCJM, Herings RMC, et al. Increased risk of Achilles tendon rupture with quinolone antibacterial use, especially in elderly patients taking oral corticosteroids. Arch Intern Med 2003; 163: 1801-7
68. Leone R, Venegoni M, Motola D, et al. Adverse drug reactions related to the use of fluoroquinolone antimicrobials: an analysis of spontaneous reports and fluoroquinolone consumption data from three Italian regions. Drug Saf 2003; 26: 109-20
69. Sendzik J, Shakibaei M, Schafer-Korting M, et al. Fluoroquinolones cause changes in extracellular matrix, signalling proteins, metalloproteinases and capsase-3 in cultured human tendon cells. Toxicology 2005; 212: 24-36
70. Blanco I, Krähenbühl S, Schlienger RG. Corticosteroid- associated tendinopathies. An analysis of the published literature and spontaneous pharmacovigilance data. Drug Saf 2005; 28: 633-43
71. Chazerain P, Hayem G, Hamza S, et al. Four cases of tendinopathy in patients on statin therapy. Joint Bone Spine 2001; 68: 430-3
72. Hernandez Rodriguez I, Allegue F. Achilles and suprapatellar tendinitis due to isotretinoin. J Rheumatol 1995; 22: 2009-10
73. Nesher G, Zuckner J. Rheumatologic complications of vitamin A and retinoids. Semin Arthritis Rheum 1995 Feb; 24 (4): 291-6
74. Vincent V, Zabraniecki L, Loustau O, et al. Acitretin-induced enthesitis in a patient with psoriatic arthritis. Joint Bone Spine 2005; 72: 326-9
75. Gerster JC, Fallet GH. Periarticular hand hydroxyapatite deposition after corticosteroid. J Rheumatol 1987; 14: 1156-9
76. Khot A, Bowditch M, Powell J, et al. The use of intradiscal steroid therapy for lumbar spinal discogenic pain. A randomized controlled trial. Spine 2004; 29: 833-7
77. Dias R, Cutts S, Massoud S. Frozen shoulder. BMJ 2005; 331: 1453-6
78. Muller LP, Muller LA, Happ J, et al. Frozen shoulder: a sympathetic dystrophy? Arch Orthop Trauma Surg 2000; 120: 84-7
79. Florence E, Schrooten W, Verdonck K, et al. Rheumatological complications associated with the use of indinavir and other protease inhibitors. Ann Rheum Dis 2002; 61: 82-4
80. Friess S, Lecocq J, Isner ME, et al. Frozen shoulder and fluoroquinolones. Two case reports. Joint Bone Spine 2000; 67: 245-9
81. Falasca GF, Toly TM, Teginato AJ, et al. Reflex sympathetic dystrophy associated with antiepileptic drugs. Epilepsia 1994; 35: 394-9
82. Villaverde V, Cantalejo M, Balsa A, et al. Leg bone pain syndrome in a kidney transplant patient with tacrolimus (FK506). Ann Rheum Dis 1999; 58: 653-4
83. Adachi JD, Papaioannou A. Corticosteroid-induced osteoporosis. Detection and management. Drug Saf 2001; 24: 607-24
84. Patschan D, Loddenkemper K, Buttgereit F. Molecular mechanisms of glucocorticoid-induced osteoporosis. Bone 2001; 29: 498-505
85. Naganathan V, Jones G, Nash P, et al. Vertebral fracture risk with long-term corticosteroid therapy. Prevalence and relation to age, bone density, and corticosteroid use. Arch Intern Med 2000; 160: 2917-22
86. Van Staa TP, Laan RF, Barton IP, et al. Bone density threshold and other predictors of vertebral fracture in patients receiving oral glucocorticoid therapy. Arthritis Rheum 2003 Nov; 48 (11): 3224-9
87. Kanis JA, Johansson H, Oden A, et al. A meta-analysis of prior corticosteroid use and fracture risk. J Bone Miner Res 2004; 19: 893-9
88. Baltzan MA, Suissa S, Bauer DC, et al. Hip fractures attributable to corticosteroid use. Lancet 1999; 353: 1327
89. Verstergaard P, Olsen ML, Johnsen SP, et al. Corticosteroid use and risk of hip fracture: a population-based case-control study in Denmark. J Intern Med 2003; 254: 486-93
90. Van Staa TP, Leufkens HGM, Abenhaim L, et al. Oral corticosteroids and fracture risk: relationship to daily and cumulative doses. Rheumatology 2000; 39: 1383-9
91. Sharma PK, Malhotia S, Pandhi P, et al. Effect of inhaled steroids on bone mineral density: a meta-analysis. J Clin Pharmacol 2003; 43: 193-7
92. Lau E, Mamdani M, Tu K. Inhaled or systemic corticosteroids and the risk of hospitalization for hip fracture among elderly women. Am J Med 2003; 114: 142-5
93. Sambrook PN. How to prevent steroid induced osteoporosis. Ann Rheum Dis 2005; 64: 176-8
94. Adler RA, Hochberg MC. Suggested guidelines for evaluation and treatment of glucocorticoid-induced osteoporosis for the department of Veterans Affairs. Arch Intern Med 2003; 163: 2619-24
95. Summey BT, Yosipovitch G. Prevention of osteoporosis associated with chronic glucocorticoid therapy. Arch Dermatol 2006; 142: 82-90
96. Hawkins D, Evans J. Minimising the risk of heparin-induced osteoporosis during pregnancy. Expert Opin Drug Saf 2005; 4: 583-90
97. Jones G, Sambrook PN. Drug-induced disorders of bone metabolism. Drug Saf 1994; 10: 480-9
98. Gage BF, Birman-Deych E, Radford MJ, et al. Risk of osteoporotic fracture in elderly patients taking warfarin: results from the National Registry of Atrial Fibrillation 2. Arch Intern Med 2006; 166: 241-6
99. Jamal SA, Browner WS, Bauer DC, et al. Warfarin use and risk for osteoporosis in elderly women. Ann Intern Med 1998; 128: 829-32
100. Wawrzynska L, Tomkowoki WZ, Przedlacki J, et al. Changes in bone density during long-term administration of low-molecular-weight heparins or acenocoumarol for secondary prophylaxis of venous thromboembolism. Pathophysiol Haemost Thromb 2003; 33: 64-7
101. Holmes-Walker DJ, Woo H, Gurney H, et al. Maintaining bone health in patients with prostate cancer. Med J Aust 2006; 184: 176-9
102. Dowsett M, Folkert E, Doody D, et al. The biology of steroid hormones and endocrine treatment of breast cancer. Breast 2005; 14: 452-7
103. Howell A, Cuzick J, Baum M, et al. Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years adjuvant treatment of breast cancer. Lancet 2005; 365: 60-2
104. Wermers RA, Hurley DL, Kearns AE. Osteoporosis associated with megestrol acetate. Mayo Clin Proc 2004; 79: 1557-61
105. Mazzantini M, Di Munno O. Methotrexate and bone mass. Clin Exp Rheumatol 2000; 18 Suppl. 21: S87-92
106. Rozin AP. Is methotrexate osteopathy a form of bone idiosyncrasy? [letter]. Ann Rheum Dis 2003; 62: 1123
107. Cummings RG. Epidemiology of medication-related falls and fractures in the elderly. Drugs Aging 1998; 12: 43-53
108. Kinjo M, Setoguchi S, Schneeweiss S, et al. Bone mineral density in subjects using central nervous system active medication. Am J Med 2005; 118: 1414.e7-1414.e12
109. Bannwarth B. Risk-benefit assessment of opioids in chronic noncancer pain. Drug Saf 1999 Oct; 21 (4): 283-96
110. Grimley Evans J. Drugs and falls in later life. Lancet 2003; 361: 448
111. Lawlor DA, Patel R, Ebrahim S. Association between falls in elderly women and chronic diseases and drug use: cross sectional study. BMJ 2003; 327: 712-5
112. O'Keane V, Meaney AM. Antipsychotic drugs: a new risk factor for osteoporosis in young women with schizophreina? J Clin Psychopharmacol 2005; 25: 26-31
113. Howes OD, Wheeler MJ, Meaney AM, et al. Bone mineral density and its relationship to prolactin levels in patients taking antpsychotic treatment. J Clin Psychopharmacol 2005; 25: 259-61
114. Jackson HA, Sheehan AH. Effect of vitamin A on fracture risk. Ann Pharmacother 2005 Dec; 39 (12): 2086-90
115. Pack AM, Morrell MJ. Adverse effects of antiepileptic drugs on bone structure. Epidemiology, mechanisms and therapeutic implications. CNS Drugs 2001; 15: 633-42
116. Andress DL, Ozuna J, Tirschwell D, et al. Antiepileptic drug-induced bone loss in young male patients who have seizures. Arch Neurol 2002; 59: 781-6
117. Pack AM, Gidal B, Vasquez B. Bone disease associated with antiepileptic drugs. Cleve Clin J Med 2004; 71 Suppl. 2: S42-8
118. Ensrud KE, Walczak TS, Blackwell T, et al. Antiepileptic drug increases rates of bone loss in older women: a prospective study. Neurology 2004; 62: 2051-7
119. Jones LC, Hungerford DS. Osteonecrosis: etiology, diagnosis, and treatment. Curr Opin Rheumatol 2004; 16: 443-9
120. McKey MD, Waddel JP, Kudo PA, et al. Osteonecrosis of the femoral head in men following short-course corticosteroid therapy: a report of 15 cases. CMAJ 2001; 164: 205-6
121. Oinuma K, Harada Y, Nawata Y, et al. Osteonecrosis in patients with systemic lupus erythematosus develops very early after starting high dose corticosteroid treatment. Ann Rheum Dis 2001; 60: 1145-8
122. Zabinski SJ, Sculo TP, Dicarlo EF, et al. Osteonecrosis in the rheumatoid femoral head. J Rheumatol 1998; 25: 1674-80
123. Marx RE. Parmidronate (Aredia) and zoledronic acid (Zometa) induced avascular necrosis of the jaws: a growing epidemic. J Oral Maxillofac Surg 2003; 61: 1115-7
124. Marx RE, Sawatari Y, Fortin M, et al. Bisphophonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment. J Oral Maxillofac Surg 2005; 63: 1567-75
125. Durie BGM, Katz M, Crowley J. Osteonecrosis of the jaw and bisphosphonates. N Engl J Med 2005; 353: 99-100
126. Wortmann RL. Lipid-lowering agents and myopathy. Curr Opin Rheumatol 2002; 14: 643-7
127. Thompson PD, Clarkson P, Karas RH. Statin-associated myopathy. JAMA 2003; 289: 1681-90
128. Ballantyne CM, Corsini A, Davidson MH, et al. Risk for myopathy with statin therapy in high risk patients. Arch Intern Med 2003; 163: 553-64
129. Graham DJ, Staffa JA, Shatin D, et al. Incidence of hospitalized rhabdomyolysis in patients treated with lipid lowering drugs. JAMA 2004; 292: 2585-90
130. Hansen KE, Hildenbrand JP, Ferguson EE, et al. Outcomes in 45 patients with statin associated myopathy. Arch Intern Med 2005; 165: 2671-6
131. Gabriel SE, Sunku J, Salvaranic C, et al. Adverse outcomes of antiinflammatory therapy among patients with polymyalgia rheumatica. Arthritis Rheum 1997; 40: 1873-8
132. Saag KG, Koehnke R, Caldwell JR, et al. Low dose long-term corticosteroid therapy in rheumatoid arthritis: an analysis of serious adverse events. Am J Med 1994; 96: 115-23
133. Casado E, Gratacos J, Tolosa C, et al. Antimalarial myopathy: an underdiagnosed complication? Prospective longitudinal study of 119 patients. Ann Rheum Dis 2006; 65: 385-90
134. Avina-Zubieta JA, Johnson ES, Suarez-Almazor ME, et al. Incidence of myopathy in patients treated with antimalarials. Report of three cases and a review of the literature. Br J Rheumatol 1995; 34: 166-70
135. Phanish MK, Krishnamurty S, Bloodworth LLO. Colchicine-induced rhabdomyolysis. Am J Med 2003; 114: 166-7
136. Ogedegbe AE, Thomas DL, Diehl AM. Hyperlactataemia syndromes associated with HIV therapy. Lancet Infect Dis 2003; 3: 329-37